Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50029090 (CHEMBL3343301) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029090 (CHEMBL3343301) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 0.0960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029091 (CHEMBL3343299) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188534 ((H-Dmt-Tic-Glu-NH-(CH(2))(5)-CO-Dap(6DMN)-NH(2) | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029095 (CHEMBL3343300) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029091 (CHEMBL3343299) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029090 (CHEMBL3343301) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188537 (CHEMBL208916 | H-Dmt-Tic-Glu-Dap(6DMN)-NH(2)) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029091 (CHEMBL3343299) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188534 ((H-Dmt-Tic-Glu-NH-(CH(2))(5)-CO-Dap(6DMN)-NH(2) | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 41.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029090 (CHEMBL3343301) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029095 (CHEMBL3343300) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188533 (CHEMBL411335 | H-Tyr-Pro-Phe-Phe-NH-(CH2)5-(C=O)-D...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188535 (CHEMBL219407 | H-Tyr-Pro-Phe-Phe-NH-(CH2)5-NH-(C=S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188535 (CHEMBL219407 | H-Tyr-Pro-Phe-Phe-NH-(CH2)5-NH-(C=S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 668 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188536 (CHEMBL207661 | H-Tyr-Pro-Dap(6DMN)-Phe-NH2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 839 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188536 (CHEMBL207661 | H-Tyr-Pro-Dap(6DMN)-Phe-NH2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188533 (CHEMBL411335 | H-Tyr-Pro-Phe-Phe-NH-(CH2)5-(C=O)-D...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029092 (CHEMBL3343304) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50188537 (CHEMBL208916 | H-Dmt-Tic-Glu-Dap(6DMN)-NH(2)) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from rat mu opioid receptor in brain P2 synaptosomes | J Med Chem 49: 3653-8 (2006) Article DOI: 10.1021/jm060343t BindingDB Entry DOI: 10.7270/Q25M65B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029091 (CHEMBL3343299) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029094 (CHEMBL3343302) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50029093 (CHEMBL3343303) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029093 (CHEMBL3343303) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029094 (CHEMBL3343302) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50029092 (CHEMBL3343304) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche Curated by ChEMBL | Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis | J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1B adrenergic receptor (Rattus norvegicus (rat)) | BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from adrenergic alpha1B receptor in Wistar rat liver membrane after 60 mins | J Med Chem 52: 7397-409 (2009) Article DOI: 10.1021/jm900458r BindingDB Entry DOI: 10.7270/Q2MG7PJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.254 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from adrenergic alpha1A receptor in Wistar rat submaxillary gland after 60 mins | J Med Chem 52: 7397-409 (2009) Article DOI: 10.1021/jm900458r BindingDB Entry DOI: 10.7270/Q2MG7PJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156158 (CHEMBL3781244) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM206344 (US9260410, 2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156162 (CHEMBL3781245) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156160 (CHEMBL3780667) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156129 (CHEMBL3782036) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50203564 ((1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5,7,8,1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.67 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]MK9112 from human recombinant adrenergic alpha2A receptor expressed in insect Sf9 cells after 60 mins | J Med Chem 52: 7397-409 (2009) Article DOI: 10.1021/jm900458r BindingDB Entry DOI: 10.7270/Q2MG7PJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142597 (US8933228, Ref 1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156135 (CHEMBL3781413) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156144 (CHEMBL3781687) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156133 (CHEMBL3782009) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50376383 (CHEMBL259972) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 141: 404-416 (2017) Article DOI: 10.1016/j.ejmech.2017.09.066 BindingDB Entry DOI: 10.7270/Q2NS0XFF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156128 (CHEMBL3780488) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156163 (CHEMBL3780832) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156157 (CHEMBL3781473) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156126 (CHEMBL3780111) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156127 (CHEMBL3781430) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14860 (1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156136 (CHEMBL3781532) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14840 (1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50156137 (CHEMBL3780714) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM13533 (1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM14862 (1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Sygnature Discovery Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi... | J Med Chem 59: 1727-46 (2016) Article DOI: 10.1021/acs.jmedchem.5b01029 BindingDB Entry DOI: 10.7270/Q2319XRB | |||||||||||
More data for this Ligand-Target Pair |
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