Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50010932 ((10-DA, 10-Deazaminopterin)2-{4-[2-(2,4-Diamino-pt...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50025009 (2-{4-[2-(2,4-Diamino-pteridin-6-yl)-1-methyl-ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50016460 ((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | 0.00600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells. | J Med Chem 35: 320-4 (1992) BindingDB Entry DOI: 10.7270/Q2WQ02RM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50008287 (2-{4-[2-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.00700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells. | J Med Chem 35: 320-4 (1992) BindingDB Entry DOI: 10.7270/Q2WQ02RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50044421 (2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-butyl]-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.00900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50008285 (2-{4-[1-(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylme...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells. | J Med Chem 35: 320-4 (1992) BindingDB Entry DOI: 10.7270/Q2WQ02RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50008286 (2-[4-(1,3-Diamino-7,8,9,10-tetrahydro-pyrimido[4,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of the dihydrofolate reductase enzyme(DHFR) derived from L1210 murine leukemia cells. | J Med Chem 35: 320-4 (1992) BindingDB Entry DOI: 10.7270/Q2WQ02RM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50044420 (2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-but-3-yn...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50044419 (2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-hexyl]-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibition of Dihydrofolate reductase (DHFR) enzyme derived from L1210 cells expressed as Ki (pM) | J Med Chem 36: 2228-31 (1993) BindingDB Entry DOI: 10.7270/Q23N22FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR)derived from Lactobacillus casei | J Med Chem 29: 1786-9 (1986) BindingDB Entry DOI: 10.7270/Q27H1HMM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022240 (2-[4-(7,9-Diamino-1,2,3,3a,4,5-hexahydro-6,8,9b-tr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR)derived from Lactobacillus casei | J Med Chem 29: 1786-9 (1986) BindingDB Entry DOI: 10.7270/Q27H1HMM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022239 (2-[4-(7,9-Diamino-1-oxo-1,2,3,3a,4,5-hexahydro-6,8...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR)derived from Lactobacillus casei | J Med Chem 29: 1786-9 (1986) BindingDB Entry DOI: 10.7270/Q27H1HMM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Escherichia coli) | BDBM50022390 (2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pter...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against thymidylate synthase of Escherichia coli | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM50022388 (2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against AICAR formyltransferase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022388 (2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM50022388 (2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against thymidylate synthase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against AICAR formyltransferase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM50022386 (2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against AICAR formyltransferase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trifunctional purine biosynthetic protein adenosine-3 (Homo sapiens (Human)) | BDBM50022388 (2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against GAR transformylase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trifunctional purine biosynthetic protein adenosine-3 (Homo sapiens (Human)) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against GAR transformylase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM50022387 (2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against AICAR formyltransferase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trifunctional purine biosynthetic protein adenosine-3 (Homo sapiens (Human)) | BDBM50022387 (2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against GAR transformylase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trifunctional purine biosynthetic protein adenosine-3 (Homo sapiens (Human)) | BDBM50022386 (2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against GAR transformylase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM50022385 (2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against AICAR formyltransferase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trifunctional purine biosynthetic protein adenosine-3 (Homo sapiens (Human)) | BDBM50022385 (2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against GAR transformylase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022387 (2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM50022387 (2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against thymidylate synthase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against thymidylate synthase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of thymidylate synthase (TS) derived from Lactobacillus casei | J Med Chem 29: 1786-9 (1986) BindingDB Entry DOI: 10.7270/Q27H1HMM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM50022385 (2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against thymidylate synthase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM50022239 (2-[4-(7,9-Diamino-1-oxo-1,2,3,3a,4,5-hexahydro-6,8...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of thymidylate synthase (TS) derived from Lactobacillus casei | J Med Chem 29: 1786-9 (1986) BindingDB Entry DOI: 10.7270/Q27H1HMM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022385 (2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022386 (2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM50022386 (2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against thymidylate synthase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Lactobacillus casei) | BDBM50022240 (2-[4-(7,9-Diamino-1,2,3,3a,4,5-hexahydro-6,8,9b-tr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of thymidylate synthase (TS) derived from Lactobacillus casei | J Med Chem 29: 1786-9 (1986) BindingDB Entry DOI: 10.7270/Q27H1HMM | |||||||||||
More data for this Ligand-Target Pair |