Found 669 hits with Last Name = 'conner' and Initial = 'se' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217410
(CHEMBL105762)Show SMILES C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H26N2O/c1-17-4-5-18(2)24(17)14-3-15-25-22-12-10-21(11-13-22)20-8-6-19(16-23)7-9-20/h6-13,17-18H,3-5,14-15H2,1-2H3/t17-,18-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.676 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119704
(CHEMBL104809 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES Fc1cccc(c1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27FN2O4S/c24-19-3-1-4-22(15-19)31(28,29)25-20-11-13-26(16-20)12-2-14-30-21-9-7-18(8-10-21)23(27)17-5-6-17/h1,3-4,7-10,15,17,20,25H,2,5-6,11-14,16H2/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217412
(CHEMBL322873)Show InChI InChI=1S/C22H26N2O/c1-18-4-2-13-24(17-18)14-3-15-25-22-11-9-21(10-12-22)20-7-5-19(16-23)6-8-20/h5-12,18H,2-4,13-15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119707
(4-[3-(4-Hexanoyl-phenoxy)-propyl]-piperazine-1-car...)Show InChI InChI=1S/C22H34N2O4/c1-3-5-6-8-21(25)19-9-11-20(12-10-19)28-18-7-13-23-14-16-24(17-15-23)22(26)27-4-2/h9-12H,3-8,13-18H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards rats Histamine type 3 (H3) receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217416
(CHEMBL105515)Show InChI InChI=1S/C23H28N2O/c1-18-5-3-6-19(2)25(18)15-4-16-26-23-13-11-22(12-14-23)21-9-7-20(17-24)8-10-21/h7-14,18-19H,3-6,15-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119721
(CHEMBL103027 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES Cc1cccc(c1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C24H30N2O4S/c1-18-4-2-5-23(16-18)31(28,29)25-21-12-14-26(17-21)13-3-15-30-22-10-8-20(9-11-22)24(27)19-6-7-19/h2,4-5,8-11,16,19,21,25H,3,6-7,12-15,17H2,1H3/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119710
(CHEMBL104618 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES Fc1ccccc1S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27FN2O4S/c24-21-4-1-2-5-22(21)31(28,29)25-19-12-14-26(16-19)13-3-15-30-20-10-8-18(9-11-20)23(27)17-6-7-17/h1-2,4-5,8-11,17,19,25H,3,6-7,12-16H2/t19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119735
(3-Cyano-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenox...)Show SMILES O=C(C1CC1)c1ccc(OCCCN2CC[C@@H](C2)NS(=O)(=O)c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C24H27N3O4S/c25-16-18-3-1-4-23(15-18)32(29,30)26-21-11-13-27(17-21)12-2-14-31-22-9-7-20(8-10-22)24(28)19-5-6-19/h1,3-4,7-10,15,19,21,26H,2,5-6,11-14,17H2/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50240709
((R)-4'-(3-(3-(dimethylamino)pyrrolidin-1-yl)propox...)Show SMILES CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 |r| Show InChI InChI=1S/C22H27N3O/c1-24(2)21-12-14-25(17-21)13-3-15-26-22-10-8-20(9-11-22)19-6-4-18(16-23)5-7-19/h4-11,21H,3,12-15,17H2,1-2H3/t21-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119722
(CHEMBL107162 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES COc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C24H30N2O5S/c1-30-21-9-11-23(12-10-21)32(28,29)25-20-13-15-26(17-20)14-2-16-31-22-7-5-19(6-8-22)24(27)18-3-4-18/h5-12,18,20,25H,2-4,13-17H2,1H3/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119705
(CHEMBL101691 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES O=C(C1CC1)c1ccc(OCCCN2CC[C@@H](C2)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C23H28N2O4S/c26-23(18-7-8-18)19-9-11-21(12-10-19)29-16-4-14-25-15-13-20(17-25)24-30(27,28)22-5-2-1-3-6-22/h1-3,5-6,9-12,18,20,24H,4,7-8,13-17H2/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119712
(3-Chloro-N-{(S)-1-[3-(4-cyclopropanecarbonyl-pheno...)Show SMILES Clc1cccc(c1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27ClN2O4S/c24-19-3-1-4-22(15-19)31(28,29)25-20-11-13-26(16-20)12-2-14-30-21-9-7-18(8-10-21)23(27)17-5-6-17/h1,3-4,7-10,15,17,20,25H,2,5-6,11-14,16H2/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119701
(CHEMBL104808 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES Fc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27FN2O4S/c24-19-6-10-22(11-7-19)31(28,29)25-20-12-14-26(16-20)13-1-15-30-21-8-4-18(5-9-21)23(27)17-2-3-17/h4-11,17,20,25H,1-3,12-16H2/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119711
(2-Chloro-N-{(S)-1-[3-(4-cyclopropanecarbonyl-pheno...)Show SMILES Clc1ccccc1S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27ClN2O4S/c24-21-4-1-2-5-22(21)31(28,29)25-19-12-14-26(16-19)13-3-15-30-20-10-8-18(9-11-20)23(27)17-6-7-17/h1-2,4-5,8-11,17,19,25H,3,6-7,12-16H2/t19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119728
(4-Chloro-N-{(S)-1-[3-(4-cyclopropanecarbonyl-pheno...)Show SMILES Clc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27ClN2O4S/c24-19-6-10-22(11-7-19)31(28,29)25-20-12-14-26(16-20)13-1-15-30-21-8-4-18(5-9-21)23(27)17-2-3-17/h4-11,17,20,25H,1-3,12-16H2/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50404001
(CHEMBL2112451)Show SMILES O=C(C1CC1)c1ccc(OCCCN2CC[C@@H](C2)NS(=O)(=O)c2ccc(cc2)C#N)cc1 |r| Show InChI InChI=1S/C24H27N3O4S/c25-16-18-2-10-23(11-3-18)32(29,30)26-21-12-14-27(17-21)13-1-15-31-22-8-6-20(7-9-22)24(28)19-4-5-19/h2-3,6-11,19,21,26H,1,4-5,12-15,17H2/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217413
(CHEMBL2112461)Show SMILES C[C@@]1(O)CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C21H24N2O2/c1-21(24)11-13-23(16-21)12-2-14-25-20-9-7-19(8-10-20)18-5-3-17(15-22)4-6-18/h3-10,24H,2,11-14,16H2,1H3/t21-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119720
(CHEMBL107293 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C24H30N2O4S/c1-18-3-11-23(12-4-18)31(28,29)25-21-13-15-26(17-21)14-2-16-30-22-9-7-20(8-10-22)24(27)19-5-6-19/h3-4,7-12,19,21,25H,2,5-6,13-17H2,1H3/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119702
(CHEMBL102925 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C25H32N2O4S/c1-2-19-4-12-24(13-5-19)32(29,30)26-22-14-16-27(18-22)15-3-17-31-23-10-8-21(9-11-23)25(28)20-6-7-20/h4-5,8-13,20,22,26H,2-3,6-7,14-18H2,1H3/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119736
(4-Bromo-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenox...)Show SMILES Brc1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C23H27BrN2O4S/c24-19-6-10-22(11-7-19)31(28,29)25-20-12-14-26(16-20)13-1-15-30-21-8-4-18(5-9-21)23(27)17-2-3-17/h4-11,17,20,25H,1-3,12-16H2/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119725
(4-tert-Butyl-N-{(S)-1-[3-(4-cyclopropanecarbonyl-p...)Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C27H36N2O4S/c1-27(2,3)22-9-13-25(14-10-22)34(31,32)28-23-15-17-29(19-23)16-4-18-33-24-11-7-21(8-12-24)26(30)20-5-6-20/h7-14,20,23,28H,4-6,15-19H2,1-3H3/t23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119733
(CHEMBL102840 | N-{(S)-1-[3-(4-Acetyl-phenoxy)-prop...)Show SMILES CC(=O)c1ccc(OCCCN2CC[C@@H](C2)NS(=O)(=O)c2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C22H25N3O4S/c1-17(26)19-5-7-21(8-6-19)29-14-2-12-25-13-11-20(16-25)24-30(27,28)22-9-3-18(15-23)4-10-22/h3-10,20,24H,2,11-14,16H2,1H3/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217096
(CHEMBL105267)Show SMILES N[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C20H23N3O/c21-14-16-2-4-17(5-3-16)18-6-8-20(9-7-18)24-13-1-11-23-12-10-19(22)15-23/h2-9,19H,1,10-13,15,22H2/t19-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine 3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217410
(CHEMBL105762)Show SMILES C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H26N2O/c1-17-4-5-18(2)24(17)14-3-15-25-22-12-10-21(11-13-22)20-8-6-19(16-23)7-9-20/h6-13,17-18H,3-5,14-15H2,1-2H3/t17-,18-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217149
(CHEMBL102984)Show InChI InChI=1S/C22H26N2O/c1-18-5-2-3-14-24(18)15-4-16-25-22-12-10-21(11-13-22)20-8-6-19(17-23)7-9-20/h6-13,18H,2-5,14-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217101
(CHEMBL25688)Show InChI InChI=1S/C20H22N2O/c21-16-17-4-6-18(7-5-17)19-8-10-20(11-9-19)23-15-3-14-22-12-1-2-13-22/h4-11H,1-3,12-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine 3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217103
(CHEMBL104669)Show SMILES O[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C20H22N2O2/c21-14-16-2-4-17(5-3-16)18-6-8-20(9-7-18)24-13-1-11-22-12-10-19(23)15-22/h2-9,19,23H,1,10-13,15H2/t19-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine 3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217150
(CHEMBL105967)Show InChI InChI=1S/C21H25N3O/c22-17-18-3-5-19(6-4-18)20-7-9-21(10-8-20)25-16-2-14-24-13-1-11-23-12-15-24/h3-10,23H,1-2,11-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217408
(CHEMBL106545)Show SMILES CN[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C21H25N3O/c1-23-20-11-13-24(16-20)12-2-14-25-21-9-7-19(8-10-21)18-5-3-17(15-22)4-6-18/h3-10,20,23H,2,11-14,16H2,1H3/t20-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217411
(CHEMBL323562)Show InChI InChI=1S/C22H26N2O/c1-18-11-14-24(15-12-18)13-2-16-25-22-9-7-21(8-10-22)20-5-3-19(17-23)4-6-20/h3-10,18H,2,11-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119698
(1-Methyl-1H-imidazole-4-sulfonic acid {(S)-1-[3-(4...)Show SMILES Cn1cnc(c1)S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C21H28N4O4S/c1-24-14-20(22-15-24)30(27,28)23-18-9-11-25(13-18)10-2-12-29-19-7-5-17(6-8-19)21(26)16-3-4-16/h5-8,14-16,18,23H,2-4,9-13H2,1H3/t18-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119730
(CHEMBL102929 | N-{(S)-1-[3-(4-Cyclopropanecarbonyl...)Show SMILES Cc1ccccc1S(=O)(=O)N[C@H]1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)C1 Show InChI InChI=1S/C24H30N2O4S/c1-18-5-2-3-6-23(18)31(28,29)25-21-13-15-26(17-21)14-4-16-30-22-11-9-20(10-12-22)24(27)19-7-8-19/h2-3,5-6,9-12,19,21,25H,4,7-8,13-17H2,1H3/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119708
(2-Cyano-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenox...)Show SMILES O=C(C1CC1)c1ccc(OCCCN2CC[C@@H](C2)NS(=O)(=O)c2ccccc2C#N)cc1 Show InChI InChI=1S/C24H27N3O4S/c25-16-20-4-1-2-5-23(20)32(29,30)26-21-12-14-27(17-21)13-3-15-31-22-10-8-19(9-11-22)24(28)18-6-7-18/h1-2,4-5,8-11,18,21,26H,3,6-7,12-15,17H2/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50240709
((R)-4'-(3-(3-(dimethylamino)pyrrolidin-1-yl)propox...)Show SMILES CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 |r| Show InChI InChI=1S/C22H27N3O/c1-24(2)21-12-14-25(17-21)13-3-15-26-22-10-8-20(9-11-22)19-6-4-18(16-23)5-7-19/h4-11,21H,3,12-15,17H2,1-2H3/t21-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217150
(CHEMBL105967)Show InChI InChI=1S/C21H25N3O/c22-17-18-3-5-19(6-4-18)20-7-9-21(10-8-20)25-16-2-14-24-13-1-11-23-12-15-24/h3-10,23H,1-2,11-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217411
(CHEMBL323562)Show InChI InChI=1S/C22H26N2O/c1-18-11-14-24(15-12-18)13-2-16-25-22-9-7-21(8-10-22)20-5-3-19(17-23)4-6-20/h3-10,18H,2,11-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217418
(CHEMBL421026)Show InChI InChI=1S/C22H25N3O/c23-12-17-2-4-18(5-3-17)19-6-8-22(9-7-19)26-11-1-10-25-15-20-13-24-14-21(20)16-25/h2-9,20-21,24H,1,10-11,13-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217413
(CHEMBL2112461)Show SMILES C[C@@]1(O)CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C21H24N2O2/c1-21(24)11-13-23(16-21)12-2-14-25-20-9-7-19(8-10-20)18-5-3-17(15-22)4-6-18/h3-10,24H,2,11-14,16H2,1H3/t21-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217416
(CHEMBL105515)Show InChI InChI=1S/C23H28N2O/c1-18-5-3-6-19(2)25(18)15-4-16-26-23-13-11-22(12-14-23)21-9-7-20(17-24)8-10-21/h7-14,18-19H,3-6,15-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50404002
(CHEMBL2112452)Show SMILES OC(=O)CCNC(=O)N1C[C@@H]2C[C@H]1CN2CCCOc1ccc(cc1)C(=O)C1CC1 Show InChI InChI=1S/C22H29N3O5/c26-20(27)8-9-23-22(29)25-14-17-12-18(25)13-24(17)10-1-11-30-19-6-4-16(5-7-19)21(28)15-2-3-15/h4-7,15,17-18H,1-3,8-14H2,(H,23,29)(H,26,27)/t17-,18-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50119739
(CHEMBL102794 | {4-[3-((1S,4S)-5-Benzenesulfonyl-2,...)Show SMILES O=C(C1CC1)c1ccc(OCCCN2C[C@@H]3C[C@H]2CN3S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C24H28N2O4S/c27-24(18-7-8-18)19-9-11-22(12-10-19)30-14-4-13-25-16-21-15-20(25)17-26(21)31(28,29)23-5-2-1-3-6-23/h1-3,5-6,9-12,18,20-21H,4,7-8,13-17H2/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against rat histamine H3 receptor |
Bioorg Med Chem Lett 12: 3055-8 (2002)
BindingDB Entry DOI: 10.7270/Q2B56J3P |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217102
(CHEMBL318801)Show InChI InChI=1S/C20H22N2O2/c21-14-16-2-4-17(5-3-16)18-6-8-20(9-7-18)24-13-1-11-22-12-10-19(23)15-22/h2-9,19,23H,1,10-13,15H2/t19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine 3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217149
(CHEMBL102984)Show InChI InChI=1S/C22H26N2O/c1-18-5-2-3-14-24(18)15-4-16-25-22-12-10-21(11-13-22)20-8-6-19(17-23)7-9-20/h6-13,18H,2-5,14-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217099
(CHEMBL106483)Show InChI InChI=1S/C20H22N2O2/c21-16-17-2-4-18(5-3-17)19-6-8-20(9-7-19)24-13-1-10-22-11-14-23-15-12-22/h2-9H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217412
(CHEMBL322873)Show InChI InChI=1S/C22H26N2O/c1-18-4-2-13-24(17-18)14-3-15-25-22-11-9-21(10-12-22)20-7-5-19(16-23)6-8-20/h5-12,18H,2-4,13-15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217105
(CHEMBL320178)Show SMILES CCOC(=O)N1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)CC1 Show InChI InChI=1S/C23H27N3O3/c1-2-28-23(27)26-15-13-25(14-16-26)12-3-17-29-22-10-8-21(9-11-22)20-6-4-19(18-24)5-7-20/h4-11H,2-3,12-17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50217415
(CHEMBL105669)Show SMILES CCOC(=O)N1CCN(CCCOc2ccc(cc2)-c2ccc(cc2C)C#N)CC1 Show InChI InChI=1S/C24H29N3O3/c1-3-29-24(28)27-14-12-26(13-15-27)11-4-16-30-22-8-6-21(7-9-22)23-10-5-20(18-25)17-19(23)2/h5-10,17H,3-4,11-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity of human cortical histamine H1 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217408
(CHEMBL106545)Show SMILES CN[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C21H25N3O/c1-23-20-11-13-24(16-20)12-2-14-25-21-9-7-19(8-10-21)18-5-3-17(15-22)4-6-18/h3-10,20,23H,2,11-14,16H2,1H3/t20-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217330
(CHEMBL106596)Show InChI InChI=1S/C21H24N2O2/c22-15-17-4-6-18(7-5-17)19-8-10-21(11-9-19)25-14-2-13-23-12-1-3-20(24)16-23/h4-11,20,24H,1-3,12-14,16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human cloned Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217414
(CHEMBL102416)Show InChI InChI=1S/C21H24N2O2/c22-16-17-2-4-18(5-3-17)19-6-8-21(9-7-19)25-15-1-12-23-13-10-20(24)11-14-23/h2-9,20,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 3077-9 (2002)
BindingDB Entry DOI: 10.7270/Q2ZW1P38 |
More data for this Ligand-Target Pair | |