Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50345813 (3-((S)-1-(dimethylamino)ethyl)phenylmethyl((S)-1-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50345812 (3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 302 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50345813 (3-((S)-1-(dimethylamino)ethyl)phenylmethyl((S)-1-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 334 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50345810 (3-((S)-1-(dimethylamino)ethyl)phenyl(R)-1-phenylpr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 404 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50345810 (3-((S)-1-(dimethylamino)ethyl)phenyl(R)-1-phenylpr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 416 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50345811 (3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 508 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 2.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50345811 (3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Homo sapiens (Human)) | BDBM50345812 (3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sention Inc. Curated by ChEMBL | Assay Description Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's method | Bioorg Med Chem Lett 19: 3243-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.089 BindingDB Entry DOI: 10.7270/Q2VQ3300 | |||||||||||
More data for this Ligand-Target Pair |