Found 237 hits with Last Name = 'coruzzi' and Initial = 'g' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50150945
(CHEBI:81390 | Immepip)Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50475340
(Methimepip)Show InChI InChI=1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12) | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22564
(2-arylbenzimidazole derivative, 10 | 2-{2-chloro-4...)Show SMILES CN1CCCN(CCCOc2ccc(-c3nc4c(C)cc(C)cc4[nH]3)c(Cl)c2)CC1 Show InChI InChI=1S/C24H31ClN4O/c1-17-14-18(2)23-22(15-17)26-24(27-23)20-7-6-19(16-21(20)25)30-13-5-10-29-9-4-8-28(3)11-12-29/h6-7,14-16H,4-5,8-13H2,1-3H3,(H,26,27) | PDB
Reactome pathway
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GoogleScholar
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| PC cid
PC sid
UniChem
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| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50361015
(CHEMBL592379)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C21H25ClN6O2S/c1-27-10-12-28(13-11-27)21-24-19-8-7-16(22)15-18(19)20(25-21)23-9-14-31(29,30)26-17-5-3-2-4-6-17/h2-8,15,26H,9-14H2,1H3,(H,23,24,25) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Binding affinity to rat histamine H4 receptor |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
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| Article
PubMed
| 4.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415482
(CHEMBL591011)Show SMILES CNS(=O)(=O)CCNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C16H23ClN6O2S/c1-18-26(24,25)10-5-19-15-13-11-12(17)3-4-14(13)20-16(21-15)23-8-6-22(2)7-9-23/h3-4,11,18H,5-10H2,1-2H3,(H,19,20,21) | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
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PubMed
| 4.27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415489
(CHEMBL591969)Show SMILES CN1CCN(CC1)c1nc(NCCS(N)(=O)=O)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C15H21ClN6O2S/c1-21-5-7-22(8-6-21)15-19-13-3-2-11(16)10-12(13)14(20-15)18-4-9-25(17,23)24/h2-3,10H,4-9H2,1H3,(H2,17,23,24)(H,18,19,20) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 4.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50361015
(CHEMBL592379)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C21H25ClN6O2S/c1-27-10-12-28(13-11-27)21-24-19-8-7-16(22)15-18(19)20(25-21)23-9-14-31(29,30)26-17-5-3-2-4-6-17/h2-8,15,26H,9-14H2,1H3,(H,23,24,25) | PDB
Reactome pathway
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415486
(CHEMBL592663)Show SMILES CN(c1ccccc1)S(=O)(=O)CCNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C22H27ClN6O2S/c1-27-11-13-29(14-12-27)22-25-20-9-8-17(23)16-19(20)21(26-22)24-10-15-32(30,31)28(2)18-6-4-3-5-7-18/h3-9,16H,10-15H2,1-2H3,(H,24,25,26) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 5.37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50361014
(CHEMBL260549 | VUF-10214)Show InChI InChI=1S/C13H14Cl2N4O/c1-18-2-4-19(5-3-18)12-13(20)17-11-7-9(15)8(14)6-10(11)16-12/h6-7H,2-5H2,1H3,(H,17,20) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 51: 2457-67 (2008)
Article DOI: 10.1021/jm7014217
BindingDB Entry DOI: 10.7270/Q22V2JWW |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50361014
(CHEMBL260549 | VUF-10214)Show InChI InChI=1S/C13H14Cl2N4O/c1-18-2-4-19(5-3-18)12-13(20)17-11-7-9(15)8(14)6-10(11)16-12/h6-7H,2-5H2,1H3,(H,17,20) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 5.62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415494
(CHEMBL592434)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2cc(I)ccc2n1 Show InChI InChI=1S/C21H25IN6O2S/c1-27-10-12-28(13-11-27)21-24-19-8-7-16(22)15-18(19)20(25-21)23-9-14-31(29,30)26-17-5-3-2-4-6-17/h2-8,15,26H,9-14H2,1H3,(H,23,24,25) | PDB
Reactome pathway
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50475338
(CHEMBL179302)Show SMILES CN1CCC(CC1)=Cc1c[nH]cn1 |(4.77,1,;3.23,.97,;2.48,-.36,;.94,-.38,;.15,.95,;.89,2.26,;2.46,2.3,;-1.39,.97,;-2.19,-.33,;-3.68,-.63,;-3.87,-2.17,;-2.49,-2.81,;-1.44,-1.69,)| Show InChI InChI=1S/C10H15N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h6-8H,2-5H2,1H3,(H,11,12) | PDB
Reactome pathway
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50474425
(CHEMBL356666)Show SMILES C1CC(CCN1)=Cc1c[nH]cn1 |(1.48,1.21,;-.04,1.44,;-.6,2.89,;.37,4.08,;1.9,3.85,;2.46,2.41,;-2.12,3.13,;-3.09,1.91,;-4.62,1.98,;-5.16,.53,;-3.97,-.4,;-2.68,.46,)| Show InChI InChI=1S/C9H13N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h5-7,10H,1-4H2,(H,11,12) | PDB
Reactome pathway
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412494
(CHEMBL452847 | VUF-10497)Show InChI InChI=1S/C18H20ClN5S/c1-23-6-8-24(9-7-23)18-21-16-5-4-13(19)11-15(16)17(22-18)20-12-14-3-2-10-25-14/h2-5,10-11H,6-9,12H2,1H3,(H,20,21,22) | PDB
Reactome pathway
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AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415480
(CHEMBL591500)Show SMILES CCN(CC)S(=O)(=O)CCNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C19H29ClN6O2S/c1-4-26(5-2)29(27,28)13-8-21-18-16-14-15(20)6-7-17(16)22-19(23-18)25-11-9-24(3)10-12-25/h6-7,14H,4-5,8-13H2,1-3H3,(H,21,22,23) | PDB
Reactome pathway
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412494
(CHEMBL452847 | VUF-10497)Show InChI InChI=1S/C18H20ClN5S/c1-23-6-8-24(9-7-23)18-21-16-5-4-13(19)11-15(16)17(22-18)20-12-14-3-2-10-25-14/h2-5,10-11H,6-9,12H2,1H3,(H,20,21,22) | PDB
Reactome pathway
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GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50191289
(7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)Show SMILES CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Oc2ccccc12 |t:8| Show InChI InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-12-13(19)6-7-15(17)20-18/h2-7,12H,8-11H2,1H3 | PDB
Reactome pathway
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Binding affinity to histamine H1 receptor |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415500
(CHEMBL591496)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2c(cccc2n1)C(F)(F)F Show InChI InChI=1S/C22H25F3N6O2S/c1-30-11-13-31(14-12-30)21-27-18-9-5-8-17(22(23,24)25)19(18)20(28-21)26-10-15-34(32,33)29-16-6-3-2-4-7-16/h2-9,29H,10-15H2,1H3,(H,26,27,28) | PDB
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 8.13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415485
(CHEMBL591250)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)N2CCOCC2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C19H27ClN6O3S/c1-24-5-7-25(8-6-24)19-22-17-3-2-15(20)14-16(17)18(23-19)21-4-13-30(27,28)26-9-11-29-12-10-26/h2-3,14H,4-13H2,1H3,(H,21,22,23) | PDB
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415484
(CHEMBL591249)Show SMILES CC1CCCCN1S(=O)(=O)CCNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C21H31ClN6O2S/c1-16-5-3-4-9-28(16)31(29,30)14-8-23-20-18-15-17(22)6-7-19(18)24-21(25-20)27-12-10-26(2)11-13-27/h6-7,15-16H,3-5,8-14H2,1-2H3,(H,23,24,25) | PDB
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| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50475348
(CHEMBL179873)Show InChI InChI=1S/C17H23N3/c1-2-4-15(5-3-1)6-9-20-10-7-16(8-11-20)12-17-13-18-14-19-17/h1-5,13-14,16H,6-12H2,(H,18,19) | PDB
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| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415499
(CHEMBL589746)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2cc(Cl)cc(Cl)c2n1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-28-8-10-29(11-9-28)21-25-19-17(13-15(22)14-18(19)23)20(26-21)24-7-12-32(30,31)27-16-5-3-2-4-6-16/h2-6,13-14,27H,7-12H2,1H3,(H,24,25,26) | PDB
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| 11.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50478300
(CHEMBL262859)Show InChI InChI=1S/C13H15ClN4O/c1-17-4-6-18(7-5-17)12-13(19)16-10-3-2-9(14)8-11(10)15-12/h2-3,8H,4-7H2,1H3,(H,16,19) | PDB
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| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 51: 2457-67 (2008)
Article DOI: 10.1021/jm7014217
BindingDB Entry DOI: 10.7270/Q22V2JWW |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50121205
(CHEBI:18295 | Histamine)Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) | PDB
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Article
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| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 51: 2457-67 (2008)
Article DOI: 10.1021/jm7014217
BindingDB Entry DOI: 10.7270/Q22V2JWW |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM7966
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) | PDB
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Article
PubMed
| 12.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415481
(CHEMBL592188)Show SMILES CN(C)S(=O)(=O)CCNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C17H25ClN6O2S/c1-22(2)27(25,26)11-6-19-16-14-12-13(18)4-5-15(14)20-17(21-16)24-9-7-23(3)8-10-24/h4-5,12H,6-11H2,1-3H3,(H,19,20,21) | PDB
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| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415498
(CHEMBL589782)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2cc(Br)c(Cl)cc2n1 Show InChI InChI=1S/C21H24BrClN6O2S/c1-28-8-10-29(11-9-28)21-25-19-14-18(23)17(22)13-16(19)20(26-21)24-7-12-32(30,31)27-15-5-3-2-4-6-15/h2-6,13-14,27H,7-12H2,1H3,(H,24,25,26) | PDB
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| 15.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50412494
(CHEMBL452847 | VUF-10497)Show InChI InChI=1S/C18H20ClN5S/c1-23-6-8-24(9-7-23)18-21-16-5-4-13(19)11-15(16)17(22-18)20-12-14-3-2-10-25-14/h2-5,10-11H,6-9,12H2,1H3,(H,20,21,22) | KEGG
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| 15.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Binding affinity to rat histamine H4 receptor |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 51: 2457-67 (2008)
Article DOI: 10.1021/jm7014217
BindingDB Entry DOI: 10.7270/Q22V2JWW |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50475354
(CHEMBL176269)Show InChI InChI=1S/C11H19N3/c1-2-14-5-3-10(4-6-14)7-11-8-12-9-13-11/h8-10H,2-7H2,1H3,(H,12,13) | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50475350
(CHEMBL176178)Show InChI InChI=1S/C15H25N3/c1-2-4-15(5-3-1)18-8-6-13(7-9-18)10-14-11-16-12-17-14/h11-13,15H,1-10H2,(H,16,17) | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415483
(CHEMBL591248)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)N2CCCC2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C19H27ClN6O2S/c1-24-9-11-25(12-10-24)19-22-17-5-4-15(20)14-16(17)18(23-19)21-6-13-29(27,28)26-7-2-3-8-26/h4-5,14H,2-3,6-13H2,1H3,(H,21,22,23) | PDB
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| 17.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415497
(CHEMBL590995)Show SMILES CN1CCN(CC1)c1nc(NCCS(=O)(=O)Nc2ccccc2)c2cc(Cl)c(Cl)cc2n1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-28-8-10-29(11-9-28)21-25-19-14-18(23)17(22)13-16(19)20(26-21)24-7-12-32(30,31)27-15-5-3-2-4-6-15/h2-6,13-14,27H,7-12H2,1H3,(H,24,25,26) | PDB
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| 19.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50412494
(CHEMBL452847 | VUF-10497)Show InChI InChI=1S/C18H20ClN5S/c1-23-6-8-24(9-7-23)18-21-16-5-4-13(19)11-15(16)17(22-18)20-12-14-3-2-10-25-14/h2-5,10-11H,6-9,12H2,1H3,(H,20,21,22) | PDB
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| 19.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]mepyramine from human histamine H1 receptor expressed in NIH3T3 cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50150945
(CHEBI:81390 | Immepip)Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12) | PDB
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| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine binding to SK-N-MC cell membranes expressing human histamine H4 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50409216
(CHEMBL150701)Show InChI InChI=1S/C10H17N3/c1(2-10-7-12-8-13-10)9-3-5-11-6-4-9/h7-9,11H,1-6H2,(H,12,13) | PDB
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| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM50397292
(CHEMBL454890 | VUF-10499)Show InChI InChI=1S/C18H20ClN5O/c1-23-5-7-24(8-6-23)18-21-16-3-2-14(19)10-15(16)17(22-18)20-11-13-4-9-25-12-13/h2-4,9-10,12H,5-8,11H2,1H3,(H,20,21,22) | KEGG
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| 24.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Binding affinity to rat histamine H4 receptor |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50191289
(7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)Show SMILES CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Oc2ccccc12 |t:8| Show InChI InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-12-13(19)6-7-15(17)20-18/h2-7,12H,8-11H2,1H3 | PDB
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| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 51: 2457-67 (2008)
Article DOI: 10.1021/jm7014217
BindingDB Entry DOI: 10.7270/Q22V2JWW |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50478303
(CHEMBL260444)Show InChI InChI=1S/C14H17ClN4O/c1-18-5-7-19(8-6-18)13-14(20-2)17-12-9-10(15)3-4-11(12)16-13/h3-4,9H,5-8H2,1-2H3 | PDB
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| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 51: 2457-67 (2008)
Article DOI: 10.1021/jm7014217
BindingDB Entry DOI: 10.7270/Q22V2JWW |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415488
(CHEMBL601946)Show SMILES CN1CCN(CC1)c1nc(NCCS(C)(=O)=O)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C16H22ClN5O2S/c1-21-6-8-22(9-7-21)16-19-14-4-3-12(17)11-13(14)15(20-16)18-5-10-25(2,23)24/h3-4,11H,5-10H2,1-2H3,(H,18,19,20) | PDB
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| 26.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50397292
(CHEMBL454890 | VUF-10499)Show InChI InChI=1S/C18H20ClN5O/c1-23-5-7-24(8-6-23)18-21-16-3-2-14(19)10-15(16)17(22-18)20-11-13-4-9-25-12-13/h2-4,9-10,12H,5-8,11H2,1H3,(H,20,21,22) | PDB
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| 26.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50191289
(7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)Show SMILES CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Oc2ccccc12 |t:8| Show InChI InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-12-13(19)6-7-15(17)20-18/h2-7,12H,8-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 28.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50475346
(CHEMBL177612)Show SMILES C1CCC(CC1)N1CCC(CC1)=Cc1c[nH]cn1 |(6,.63,;5.26,1.95,;3.72,1.98,;2.95,.68,;3.67,-.66,;5.21,-.7,;1.41,.68,;.61,-.63,;-.9,-.63,;-1.67,.72,;-.88,2.05,;.66,2.02,;-3.23,.75,;-4.03,-.56,;-5.54,-.86,;-5.73,-2.39,;-4.35,-3.04,;-3.29,-1.92,)| Show InChI InChI=1S/C15H23N3/c1-2-4-15(5-3-1)18-8-6-13(7-9-18)10-14-11-16-12-17-14/h10-12,15H,1-9H2,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor |
J Med Chem 48: 2100-7 (2005)
Article DOI: 10.1021/jm049475h
BindingDB Entry DOI: 10.7270/Q28K7CVC |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50415501
(CHEMBL591711)Show SMILES CNS(=O)(=O)CCCNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1 Show InChI InChI=1S/C17H25ClN6O2S/c1-19-27(25,26)11-3-6-20-16-14-12-13(18)4-5-15(14)21-17(22-16)24-9-7-23(2)8-10-24/h4-5,12,19H,3,6-11H2,1-2H3,(H,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 33.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412516
(CHEMBL509852 | VUF-10515)Show InChI InChI=1S/C19H22ClN5S/c1-13-5-10-26-17(13)12-21-18-15-11-14(20)3-4-16(15)22-19(23-18)25-8-6-24(2)7-9-25/h3-5,10-11H,6-9,12H2,1-2H3,(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412516
(CHEMBL509852 | VUF-10515)Show InChI InChI=1S/C19H22ClN5S/c1-13-5-10-26-17(13)12-21-18-15-11-14(20)3-4-16(15)22-19(23-18)25-8-6-24(2)7-9-25/h3-5,10-11H,6-9,12H2,1-2H3,(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412512
(CHEMBL509142 | VUF-10507)Show InChI InChI=1S/C18H20ClN5S/c1-23-5-7-24(8-6-23)18-21-16-3-2-14(19)10-15(16)17(22-18)20-11-13-4-9-25-12-13/h2-4,9-10,12H,5-8,11H2,1H3,(H,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffin Discoveries BV
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells |
J Med Chem 53: 2390-400 (2010)
Article DOI: 10.1021/jm901379s
BindingDB Entry DOI: 10.7270/Q2G44RJ4 |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412512
(CHEMBL509142 | VUF-10507)Show InChI InChI=1S/C18H20ClN5S/c1-23-5-7-24(8-6-23)18-21-16-3-2-14(19)10-15(16)17(22-18)20-11-13-4-9-25-12-13/h2-4,9-10,12H,5-8,11H2,1H3,(H,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50412515
(CHEMBL452869 | VUF-10516)Show SMILES CN1CCN(CC1)c1nc(NCc2cc(C)cs2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C19H22ClN5S/c1-13-9-15(26-12-13)11-21-18-16-10-14(20)3-4-17(16)22-19(23-18)25-7-5-24(2)6-8-25/h3-4,9-10,12H,5-8,11H2,1-2H3,(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 38.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells |
J Med Chem 51: 7855-65 (2008)
Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R |
More data for this
Ligand-Target Pair | |
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