Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478473 (CHEBI:49 | FANCHININ | NSC-77037 | Tetrandrine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 692 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478473 (CHEBI:49 | FANCHININ | NSC-77037 | Tetrandrine) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 741 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478458 (CHEBI:18417 | COCLAURINE) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478471 (7-O-benzyl-2-O-methyI-N-methylcocIaurine | CHEMBL5...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478470 (7,12-O,O''-dibenzyl-N-ethylcoclaurine | CHEMBL4530...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478469 (7,12-O,O''dibenzyl-N-methylcoclaurine | CHEMBL4527...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478471 (7-O-benzyl-2-O-methyI-N-methylcocIaurine | CHEMBL5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478464 (7-O-benzyl-N-methylcoclaurine | CHEMBL455620) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478466 (12-O-Benzylcoclaurine | CHEMBL451988) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478459 (DL-N-methylcoclaurine | METHYL COCLAURINE) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478472 (7-O-benzylcoclaurine | CHEMBL510364) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478466 (12-O-Benzylcoclaurine | CHEMBL451988) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478464 (7-O-benzyl-N-methylcoclaurine | CHEMBL455620) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478472 (7-O-benzylcoclaurine | CHEMBL510364) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478462 (7,12-O,O''-dimethyl-N-methylcoclaurine | CHEMBL452...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478465 (7-O-benzyl-12-O-methylcoclaurine | CHEMBL507843) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478468 (12-O-methyl-N''-methylcoclaurine | CHEMBL451987) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478460 (CHEMBL453293 | N-ethylcoclaurine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50013286 (CHEMBL510363 | DL-N-Norarmepavine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478474 (CHEMBL451722 | D,L-Armepavine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 7.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478469 (7,12-O,O''dibenzyl-N-methylcoclaurine | CHEMBL4527...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478462 (7,12-O,O''-dimethyl-N-methylcoclaurine | CHEMBL452...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478467 (CHEMBL114853) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478470 (7,12-O,O''-dibenzyl-N-ethylcoclaurine | CHEMBL4530...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478463 (7,12-O,O''-dibenzylcoclaurine | CHEMBL452762) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 9.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478474 (CHEMBL451722 | D,L-Armepavine) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 9.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50478461 (12-O-methylcoclaurine | CHEMBL451723) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from alpha1 adrenergic receptor in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478468 (12-O-methyl-N''-methylcoclaurine | CHEMBL451987) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478460 (CHEMBL453293 | N-ethylcoclaurine) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478459 (DL-N-methylcoclaurine | METHYL COCLAURINE) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478463 (7,12-O,O''-dibenzylcoclaurine | CHEMBL452762) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478467 (CHEMBL114853) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50478461 (12-O-methylcoclaurine | CHEMBL451723) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Chile Curated by ChEMBL | Assay Description Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane | J Nat Prod 66: 954-7 (2003) Article DOI: 10.1021/np030022+ BindingDB Entry DOI: 10.7270/Q2QZ2DRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human PDGFRbeta by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human CDK1 by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human Src kinase by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human AurA kinase by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human Akt1 by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human ROCK1 by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5447 (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human MEK1 by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human FAK by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human RAF1 by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 3 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human ERK1 by kinase inhibition assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50126847 (CHEMBL3628537) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50126846 (CHEMBL481789) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50126850 (CHEMBL3628818) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50126851 (CHEMBL3628536) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4810 ((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50126845 (CHEMBL3628814) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay | Eur J Med Chem 103: 29-43 (2015) Article DOI: 10.1016/j.ejmech.2015.08.027 BindingDB Entry DOI: 10.7270/Q2G162MG | |||||||||||
More data for this Ligand-Target Pair |
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