Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150413 (CHEMBL413049 | N-[2-(4-Fluoro-phenyl)-ethyl]-N''-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150408 (CHEMBL182937 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150407 (CHEMBL180086 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150412 (CHEMBL183862 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150410 (CHEMBL182174 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150417 (CHEMBL182322 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150405 (CHEMBL182797 | N-(2-Phenoxy-ethyl)-N''-(1-phenyl-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150421 (CHEMBL183462 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150406 (CHEMBL182418 | N-[(S)-1-(4-Fluoro-phenyl)-ethyl]-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50150407 (CHEMBL180086 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 2C receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150420 (6-Fluoro-N-(2-phenoxy-ethyl)-N''-((S)-1-phenyl-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM16452 ((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50150413 (CHEMBL413049 | N-[2-(4-Fluoro-phenyl)-ethyl]-N''-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 2C receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150414 (CHEMBL182840 | N,N-Dimethyl-N''-(2-phenoxy-ethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150411 (CHEMBL180946 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150409 (6-Methyl-N-(2-phenoxy-ethyl)-N''-((S)-1-phenyl-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150416 (CHEMBL182121 | N-(1-Phenyl-ethyl)-N''-(3-phenyl-pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50150406 (CHEMBL182418 | N-[(S)-1-(4-Fluoro-phenyl)-ethyl]-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 2C receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50150413 (CHEMBL413049 | N-[2-(4-Fluoro-phenyl)-ethyl]-N''-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 172 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 6 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50150407 (CHEMBL180086 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 6 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150415 (CHEMBL360374 | N-(2-Phenoxy-ethyl)-N''-((R)-1-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50150406 (CHEMBL182418 | N-[(S)-1-(4-Fluoro-phenyl)-ethyl]-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 6 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150419 (CHEMBL185560 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50150410 (CHEMBL182174 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 6 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50150410 (CHEMBL182174 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 2C receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50150408 (CHEMBL182937 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 6 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50150408 (CHEMBL182937 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 2C receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50150418 (CHEMBL183347 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against 5-Hydroxy tryptamine 7 receptor | Bioorg Med Chem Lett 14: 4245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.008 BindingDB Entry DOI: 10.7270/Q2GM86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50485806 (CHEMBL2164125) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D Curated by ChEMBL | Assay Description Inhibition of human gamma-secretase expressed in IMR32 cell membranes using MBPC-125 Swedish as substrate assessed as inhibition of amyloid beta40 pr... | Bioorg Med Chem Lett 22: 6828-31 (2012) Article DOI: 10.1016/j.bmcl.2012.09.057 BindingDB Entry DOI: 10.7270/Q2RJ4NBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009806 (CHEMBL20207 | [3-(7-Chloro-benzothiazol-2-ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM16452 ((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM16452 ((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Compound was tested for the rate of reduction of glyceraldehyde by human placental aldose reductase. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009763 (CHEMBL20024 | [3-(4-Fluoro-benzothiazol-2-ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM16452 ((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Compound was tested for the inhibition of the rat lens aldose reductase using the substrate as glucose. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM16452 ((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta | J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009781 (CHEMBL20169 | [3-(5-Bromo-benzothiazol-2-ylmethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50008471 (CHEMBL143234 | [3-(5,7-Difluoro-benzooxazol-2-ylme...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta | J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009828 (CHEMBL20015 | [3-(4-Chloro-benzothiazol-2-ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009784 (CHEMBL278991 | [3-(5,7-Dichloro-benzothiazol-2-ylm...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477715 (CHEMBL248647) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D Curated by ChEMBL | Assay Description Inhibition of gamma-secretase in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta40 production after 19 hrs | Bioorg Med Chem Lett 22: 6828-31 (2012) Article DOI: 10.1016/j.bmcl.2012.09.057 BindingDB Entry DOI: 10.7270/Q2RJ4NBT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009759 (CHEMBL20518 | [3-(5-Chloro-7-fluoro-benzothiazol-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009750 (CHEMBL282689 | [3-(4,7-Difluoro-benzothiazol-2-ylm...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009774 (CHEMBL20161 | [3-(5,7-Dimethyl-benzothiazol-2-ylme...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009749 (CHEMBL416001 | [3-(7-Chloro-5-fluoro-benzothiazol-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009757 (CHEMBL20637 | [3-(5,7-Difluoro-benzothiazol-2-ylme...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50008441 (CHEMBL422647 | [4-Oxo-3-(3-o-tolyl-[1,2,4]oxadiazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta | J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50008480 (CHEMBL341864 | {3-[3-(2-Bromo-phenyl)-[1,2,4]oxadi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta | J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009804 (CHEMBL283996 | [3-(5-Fluoro-benzothiazol-2-ylmethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50009829 (CHEMBL20197 | [3-(5-Chloro-benzothiazol-2-ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta. | J Med Chem 34: 108-22 (1991) BindingDB Entry DOI: 10.7270/Q2513X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50230363 (CHEMBL422476) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta | J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1 | |||||||||||
More data for this Ligand-Target Pair |
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