Found 228 hits with Last Name = 'dekeyne' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.159 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2B adrenergic receptor
(Homo sapiens (Human)) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]
(Rattus norvegicus (rat)) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473587
(CHEMBL410530)Show SMILES O[C@H]1[C@@H](Cc2ccc(cc12)[N+]([O-])=O)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H24N2O5/c25-21-18-13-16(24(26)27)5-4-15(18)12-19(21)23-8-6-14(7-9-23)17-2-1-3-20-22(17)29-11-10-28-20/h1-5,13-14,19,21,25H,6-12H2/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.288 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473612
(CHEMBL45966)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(CC1)c1cccc2CCCOc12 Show InChI InChI=1S/C23H26FNO2/c24-18-6-7-19-17(13-18)14-21(22(19)26)25-10-8-15(9-11-25)20-5-1-3-16-4-2-12-27-23(16)20/h1,3,5-7,13,15,21-22,26H,2,4,8-12,14H2/t21-,22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.302 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.346 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50396146
(CHEMBL51457)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H24FNO3/c23-16-4-5-17-15(12-16)13-19(21(17)25)24-8-6-14(7-9-24)18-2-1-3-20-22(18)27-11-10-26-20/h1-5,12,14,19,21,25H,6-11,13H2/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.437 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473603
(CHEMBL298096)Show SMILES COc1ccc2C[C@H]([C@H](O)c2c1)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H26N2O4/c1-26-16-6-5-15-13-19(21(25)17(15)14-16)24-9-7-23(8-10-24)18-3-2-4-20-22(18)28-12-11-27-20/h2-6,14,19,21,25H,7-13H2,1H3/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.447 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM85595
(CAS_105182-45-4 | Fluparoxan | NSC_72036)Show InChI InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM86708
(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473604
(CHEMBL48767)Show SMILES O[C@H]1[C@@H](Cc2cc3OCOc3cc12)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H25NO5/c25-22-17-12-21-20(28-13-29-21)11-15(17)10-18(22)24-6-4-14(5-7-24)16-2-1-3-19-23(16)27-9-8-26-19/h1-3,11-12,14,18,22,25H,4-10,13H2/t18-,22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.525 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473592
(CHEMBL301806)Show SMILES Cc1ccc2C[C@H]([C@H](O)c2c1)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H27NO3/c1-15-5-6-17-14-20(22(25)19(17)13-15)24-9-7-16(8-10-24)18-3-2-4-21-23(18)27-12-11-26-21/h2-6,13,16,20,22,25H,7-12,14H2,1H3/t20-,22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.562 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM35256
((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50396145
(CHEMBL300100)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H23FN2O3/c22-15-4-5-16-14(12-15)13-18(20(16)25)24-8-6-23(7-9-24)17-2-1-3-19-21(17)27-11-10-26-19/h1-5,12,18,20,25H,6-11,13H2/t18-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM85709
(S18616)Show InChI InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50396145
(CHEMBL300100)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H23FN2O3/c22-15-4-5-16-14(12-15)13-18(20(16)25)24-8-6-23(7-9-24)17-2-1-3-19-21(17)27-11-10-26-19/h1-5,12,18,20,25H,6-11,13H2/t18-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473607
(CHEMBL50119)Show SMILES O[C@H]1[C@@H](Cc2ccccc12)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H25NO3/c24-21-17-5-2-1-4-16(17)14-19(21)23-10-8-15(9-11-23)18-6-3-7-20-22(18)26-13-12-25-20/h1-7,15,19,21,24H,8-14H2/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473588
(CHEMBL298363)Show SMILES O[C@H]1[C@@H](Cc2ccc(cc12)[N+]([O-])=O)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H23N3O5/c25-20-16-13-15(24(26)27)5-4-14(16)12-18(20)23-8-6-22(7-9-23)17-2-1-3-19-21(17)29-11-10-28-19/h1-5,13,18,20,25H,6-12H2/t18-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.741 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473601
(CHEMBL47433)Show SMILES O[C@H]1[C@@H](Cc2ccc(F)cc12)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H24FNO3/c23-16-5-4-15-12-19(21(25)18(15)13-16)24-8-6-14(7-9-24)17-2-1-3-20-22(17)27-11-10-26-20/h1-5,13-14,19,21,25H,6-12H2/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM82564
(CAS_132787 | NSC_132787 | S 15535)Show InChI InChI=1S/C21H24N2O2/c1-2-5-17-15-18(14-16(17)4-1)22-8-10-23(11-9-22)19-6-3-7-20-21(19)25-13-12-24-20/h1-7,18H,8-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
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| Article PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473594
(CHEMBL49497)Show SMILES O[C@H]1[C@@H](Cc2ccccc12)N1CCC(=CC1)c1cccc2OCCOc12 |c:15| Show InChI InChI=1S/C22H23NO3/c24-21-17-5-2-1-4-16(17)14-19(21)23-10-8-15(9-11-23)18-6-3-7-20-22(18)26-13-12-25-20/h1-8,19,21,24H,9-14H2/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.832 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50396143
(CHEMBL300739)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(=CC1)c1cccc2OCCOc12 |c:16| Show InChI InChI=1S/C22H22FNO3/c23-16-4-5-17-15(12-16)13-19(21(17)25)24-8-6-14(7-9-24)18-2-1-3-20-22(18)27-11-10-26-20/h1-6,12,19,21,25H,7-11,13H2/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.851 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
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| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM50241196
((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...)Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 295: 1192-205 (2000)
BindingDB Entry DOI: 10.7270/Q28P5Z2C |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473590
(CHEMBL298855)Show SMILES COc1ccc2C[C@H]([C@H](O)c2c1)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H27NO4/c1-26-17-6-5-16-13-20(22(25)19(16)14-17)24-9-7-15(8-10-24)18-3-2-4-21-23(18)28-12-11-27-21/h2-6,14-15,20,22,25H,7-13H2,1H3/t20-,22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473610
(CHEMBL51882)Show SMILES Cc1ccc2[C@@H](O)[C@@H](Cc2c1)N1CCC(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H27NO3/c1-15-5-6-18-17(13-15)14-20(22(18)25)24-9-7-16(8-10-24)19-3-2-4-21-23(19)27-12-11-26-21/h2-6,13,16,20,22,25H,7-12,14H2,1H3/t20-,22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
Alpha-2B adrenergic receptor
(Homo sapiens (Human)) | BDBM85595
(CAS_105182-45-4 | Fluparoxan | NSC_72036)Show InChI InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2 | PDB
UniProtKB/SwissProt
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PC cid PC sid UniChem
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| Article PubMed
| 1.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]
(Rattus norvegicus (rat)) | BDBM85595
(CAS_105182-45-4 | Fluparoxan | NSC_72036)Show InChI InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid UniChem
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| Article PubMed
| 1.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473608
(CHEMBL298279)Show SMILES COc1ccc2[C@@H](O)[C@@H](Cc2c1)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H26N2O4/c1-26-16-5-6-17-15(13-16)14-19(21(17)25)24-9-7-23(8-10-24)18-3-2-4-20-22(18)28-12-11-27-20/h2-6,13,19,21,25H,7-12,14H2,1H3/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473608
(CHEMBL298279)Show SMILES COc1ccc2[C@@H](O)[C@@H](Cc2c1)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H26N2O4/c1-26-16-5-6-17-15(13-16)14-19(21(17)25)24-9-7-23(8-10-24)18-3-2-4-20-22(18)28-12-11-27-20/h2-6,13,19,21,25H,7-12,14H2,1H3/t19-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473597
(CHEMBL299817)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCN(CC1)c1cccc2CCCOc12 Show InChI InChI=1S/C22H25FN2O2/c23-17-6-7-18-16(13-17)14-20(21(18)26)25-10-8-24(9-11-25)19-5-1-3-15-4-2-12-27-22(15)19/h1,3,5-7,13,20-21,26H,2,4,8-12,14H2/t20-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473595
(CHEMBL49206)Show SMILES O[C@H]1[C@@H](Cc2ccc(F)cc12)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H23FN2O3/c22-15-5-4-14-12-18(20(25)16(14)13-15)24-8-6-23(7-9-24)17-2-1-3-19-21(17)27-11-10-26-19/h1-5,13,18,20,25H,6-12H2/t18-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473599
(CHEMBL297925)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCN(CC1)c1cc(Cl)cc2OCCOc12 Show InChI InChI=1S/C21H22ClFN2O3/c22-14-11-18(21-19(12-14)27-7-8-28-21)25-5-3-24(4-6-25)17-10-13-9-15(23)1-2-16(13)20(17)26/h1-2,9,11-12,17,20,26H,3-8,10H2/t17-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473598
(CHEMBL48713)Show SMILES O[C@H]1[C@@H](Cc2cc(F)ccc12)N1CCC(CC1)c1cccc2CCOc12 Show InChI InChI=1S/C22H24FNO2/c23-17-4-5-18-16(12-17)13-20(21(18)25)24-9-6-14(7-10-24)19-3-1-2-15-8-11-26-22(15)19/h1-5,12,14,20-21,25H,6-11,13H2/t20-,21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50020222
((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 1.58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)Show InChI InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
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DrugBank MCE PC cid PC sid UniChem
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| Article PubMed
| 1.58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM35256
((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| 1.58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM85595
(CAS_105182-45-4 | Fluparoxan | NSC_72036)Show InChI InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50473591
(CHEMBL299405)Show SMILES O[C@H]1[C@@H](Cc2ccccc12)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H24N2O3/c24-20-16-5-2-1-4-15(16)14-18(20)23-10-8-22(9-11-23)17-6-3-7-19-21(17)26-13-12-25-19/h1-7,18,20,24H,8-14H2/t18-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by ChEMBL
| Assay Description Binding affinity at human 5-hydroxytryptamine 1A receptor by inhibition of [3H]8-OH-DPAT binding in Chinese hamster ovary cell line |
J Med Chem 45: 165-76 (2002)
Article DOI: 10.1021/jm010975+ BindingDB Entry DOI: 10.7270/Q25D8VK9 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50005835
((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
| DrugBank Article PubMed
| 1.99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |
Alpha-2B adrenergic receptor
(Homo sapiens (Human)) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
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Similars
| Article PubMed
| 1.99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier, Centre de Recherches de Croissy
Curated by PDSP Ki Database
| |
Synapse 35: 79-95 (2000)
Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N |
More data for this Ligand-Target Pair | |