Compile Data Set for Download or QSAR

Found 434 hits with Last Name = 'denis' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM194 ((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxy-...) Show SMILES COc1cc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccccc3)N(Cc3ccc(O)c(OC)c3)C2=O)ccc1O |r| Show InChI InChI=1S/C34H37N3O6/c1-42-32-18-26(13-15-29(32)38)21-36-28(17-24-9-5-3-6-10-24)31(40)23-35(20-25-11-7-4-8-12-25)37(34(36)41)22-27-14-16-30(39)33(19-27)43-2/h3-16,18-19,28,31,38-40H,17,20-23H2,1-2H3/t28-,31-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.00500	-65.6	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM195 ((5R,6R)-1,5-dibenzyl-2-(cyclopropylmethyl)-6-hydro...) Show SMILES COc1cc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccccc3)N(CC3CC3)C2=O)ccc1O |r| Show InChI InChI=1S/C30H35N3O4/c1-37-29-17-25(14-15-27(29)34)19-32-26(16-22-8-4-2-5-9-22)28(35)21-31(18-23-10-6-3-7-11-23)33(30(32)36)20-24-12-13-24/h2-11,14-15,17,24,26,28,34-35H,12-13,16,18-21H2,1H3/t26-,28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0620	-59.2	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM192 ((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxyp...) Show SMILES O[C@@H]1CN(Cc2ccccc2)N(Cc2ccc(O)cc2)C(=O)N(Cc2ccc(O)cc2)[C@@H]1Cc1ccccc1 |r| Show InChI InChI=1S/C32H33N3O4/c36-28-15-11-26(12-16-28)21-34-30(19-24-7-3-1-4-8-24)31(38)23-33(20-25-9-5-2-6-10-25)35(32(34)39)22-27-13-17-29(37)18-14-27/h1-18,30-31,36-38H,19-23H2/t30-,31-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0700	-58.9	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062051 (1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-3-[4-(2-me...) Show SMILES COC(=O)c1cc(cc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C34H28FN5O4/c1-20-37-28-17-36-14-13-29(28)39(20)18-21-5-7-23(8-6-21)32(41)27-19-40(34(43)38(2)3)30-16-24(22-9-11-25(35)12-10-22)15-26(31(27)30)33(42)44-4/h5-17,19H,18H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062066 (3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-b...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)S(=O)(=O)C(C)C Show InChI InChI=1S/C28H26N4O5S/c1-17(2)38(35,36)32-16-22(26-21(28(34)37-4)6-5-7-25(26)32)27(33)20-10-8-19(9-11-20)15-31-18(3)30-23-14-29-13-12-24(23)31/h5-14,16-17H,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM193 ((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(3-methoxyp...) Show SMILES COc1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccccc3)N(Cc3cccc(OC)c3)C2=O)c1 |r| Show InChI InChI=1S/C34H37N3O4/c1-40-30-17-9-15-28(19-30)23-36-32(21-26-11-5-3-6-12-26)33(38)25-35(22-27-13-7-4-8-14-27)37(34(36)39)24-29-16-10-18-31(20-29)41-2/h3-20,32-33,38H,21-25H2,1-2H3/t32-,33-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.220	-56.0	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM189 ((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis({[4-(hydrox...) Show SMILES OCc1ccc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccccc3)N(Cc3ccc(CO)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C34H37N3O4/c38-24-30-15-11-28(12-16-30)21-36-32(19-26-7-3-1-4-8-26)33(40)23-35(20-27-9-5-2-6-10-27)37(34(36)41)22-29-13-17-31(25-39)18-14-29/h1-18,32-33,38-40H,19-25H2/t32-,33-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.220	-56.0	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50048485 ((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...) Show SMILES CCOC(=O)[C@H](CC(C)C)N(C)S(=O)(=O)c1ccc(Cn2c(C)nc3cnccc23)cc1 Show InChI InChI=1S/C23H30N4O4S/c1-6-31-23(28)22(13-16(2)3)26(5)32(29,30)19-9-7-18(8-10-19)15-27-17(4)25-20-14-24-12-11-21(20)27/h7-12,14,16,22H,6,13,15H2,1-5H3/t22-/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The compound was evaluated for its binding affinity against PAF receptor in rabbit platelet				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50048485 ((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...) Show SMILES CCOC(=O)[C@H](CC(C)C)N(C)S(=O)(=O)c1ccc(Cn2c(C)nc3cnccc23)cc1 Show InChI InChI=1S/C23H30N4O4S/c1-6-31-23(28)22(13-16(2)3)26(5)32(29,30)19-9-7-18(8-10-19)15-27-17(4)25-20-14-24-12-11-21(20)27/h7-12,14,16,22H,6,13,15H2,1-5H3/t22-/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The compound was evaluated for its binding affinity against PAF receptor in rabbit platelet				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM190 ((5R,6R)-2,4-Bis[4-(hydroxymethyl)benzyl]-1-(3-fura...) Show SMILES OCc1ccc(CN2[C@H](Cc3ccccc3)[C@H](O)CN(Cc3ccoc3)N(Cc3ccc(CO)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C32H35N3O5/c36-21-27-10-6-25(7-11-27)18-34-30(16-24-4-2-1-3-5-24)31(38)20-33(17-29-14-15-40-23-29)35(32(34)39)19-26-8-12-28(22-37)13-9-26/h1-15,23,30-31,36-38H,16-22H2/t30-,31-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.490	-54.0	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062069 (4-Methoxy-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...) Show SMILES COC(=O)c1[nH]c2cccc(OC)c2c1C(=O)c1ccc(Cn2c(C)nc3cnccc23)cc1 Show InChI InChI=1S/C26H22N4O4/c1-15-28-19-13-27-12-11-20(19)30(15)14-16-7-9-17(10-8-16)25(31)23-22-18(5-4-6-21(22)33-2)29-24(23)26(32)34-3/h4-13,29H,14H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062056 (1-Dimethylcarbamoyl-3-{2-[4-(2-methyl-imidazo[4,5-...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)Cc3ccc(cc3)-n3c(C)nc4cnccc34)c12)C(=O)N(C)C Show InChI InChI=1S/C28H25N5O4/c1-17-30-22-15-29-13-12-23(22)33(17)19-10-8-18(9-11-19)14-25(34)21-16-32(28(36)31(2)3)24-7-5-6-20(26(21)24)27(35)37-4/h5-13,15-16H,14H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062101 (4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...) Show SMILES CNC(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c2c(cccc12)C#C Show InChI InChI=1S/C27H20FN5O2/c1-4-17-6-5-7-24-25(17)20(15-33(24)27(35)29-3)26(34)18-8-9-19(21(28)12-18)14-32-16(2)31-22-13-30-11-10-23(22)32/h1,5-13,15H,14H2,2-3H3,(H,29,35)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062061 (1-(3,3-Dimethyl-2-oxo-butyl)-3-[4-(2-methyl-imidaz...) Show SMILES COC(=O)c1cccc2n(CC(=O)C(C)(C)C)cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12 Show InChI InChI=1S/C31H30N4O4/c1-19-33-24-15-32-14-13-25(24)35(19)16-20-9-11-21(12-10-20)29(37)23-17-34(18-27(36)31(2,3)4)26-8-6-7-22(28(23)26)30(38)39-5/h6-15,17H,16,18H2,1-5H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062045 (6-Benzofuran-2-yl-1-dimethylcarbamoyl-3-[4-(2-meth...) Show SMILES COC(=O)c1cc(cc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C)-c1cc2ccccc2o1 Show InChI InChI=1S/C36H29N5O5/c1-21-38-28-18-37-14-13-29(28)40(21)19-22-9-11-23(12-10-22)34(42)27-20-41(36(44)39(2)3)30-16-25(15-26(33(27)30)35(43)45-4)32-17-24-7-5-6-8-31(24)46-32/h5-18,20H,19H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062082 (4-Methyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(C)cccc12 Show InChI InChI=1S/C27H25N5O2/c1-17-6-5-7-24-25(17)21(16-32(24)27(34)30(3)4)26(33)20-10-8-19(9-11-20)15-31-18(2)29-22-14-28-13-12-23(22)31/h5-14,16H,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062113 (1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C28H25N5O4/c1-17-30-22-14-29-13-12-23(22)32(17)15-18-8-10-19(11-9-18)26(34)21-16-33(28(36)31(2)3)24-7-5-6-20(25(21)24)27(35)37-4/h5-14,16H,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062064 (1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OCc1ccccc1 Show InChI InChI=1S/C34H29N5O4/c1-22-36-28-18-35-17-16-29(28)38(22)19-23-12-14-25(15-13-23)32(40)27-20-39(34(42)37(2)3)30-11-7-10-26(31(27)30)33(41)43-21-24-8-5-4-6-9-24/h4-18,20H,19,21H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062092 ((4,7-Dimethyl-1H-indol-3-yl)-[4-(2-methyl-imidazo[...) Show SMILES Cc1nc2cnccc2n1Cc1ccc(cc1)C(=O)c1c[nH]c2c(C)ccc(C)c12 Show InChI InChI=1S/C25H22N4O/c1-15-4-5-16(2)24-23(15)20(12-27-24)25(30)19-8-6-18(7-9-19)14-29-17(3)28-21-13-26-11-10-22(21)29/h4-13,27H,14H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062106 (4-Chloro-3-[4-(2-methyl-imidazo[4,5-b]pyridin-1-yl...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4ncccc34)cc2)c2c(Cl)cccc12 Show InChI InChI=1S/C26H22ClN5O2/c1-16-29-25-22(8-5-13-28-25)31(16)14-17-9-11-18(12-10-17)24(33)19-15-32(26(34)30(2)3)21-7-4-6-20(27)23(19)21/h4-13,15H,14H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062118 (4-Ethyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylm...) Show SMILES CCc1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C28H27N5O2/c1-5-20-7-6-8-25-26(20)22(17-33(25)28(35)31(3)4)27(34)21-11-9-19(10-12-21)16-32-18(2)30-23-15-29-14-13-24(23)32/h6-15,17H,5,16H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062048 (1-Dimethylcarbamoyl-3-[4-(2-methyl-benzoimidazol-1...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5ccccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C29H26N4O4/c1-18-30-23-9-5-6-10-24(23)32(18)16-19-12-14-20(15-13-19)27(34)22-17-33(29(36)31(2)3)25-11-7-8-21(26(22)25)28(35)37-4/h5-15,17H,16H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062098 (1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES COC(=O)c1cc(cc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C)C#Cc1ccccc1 Show InChI InChI=1S/C36H29N5O4/c1-23-38-30-20-37-17-16-31(30)40(23)21-25-12-14-27(15-13-25)34(42)29-22-41(36(44)39(2)3)32-19-26(11-10-24-8-6-5-7-9-24)18-28(33(29)32)35(43)45-4/h5-9,12-20,22H,21H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062054 (4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c2c(cccc12)C#C Show InChI InChI=1S/C28H22FN5O2/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33/h1,6-14,16H,15H2,2-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062054 (4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c2c(cccc12)C#C Show InChI InChI=1S/C28H22FN5O2/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33/h1,6-14,16H,15H2,2-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062091 (1-(2-Ethoxy-ethyl)-3-[4-(2-methyl-imidazo[4,5-c]py...) Show SMILES CCOCCn1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OC Show InChI InChI=1S/C29H28N4O4/c1-4-37-15-14-32-18-23(27-22(29(35)36-3)6-5-7-26(27)32)28(34)21-10-8-20(9-11-21)17-33-19(2)31-24-16-30-13-12-25(24)33/h5-13,16,18H,4,14-15,17H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062058 (6-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(c2ccc(cc12)-c1ccc(F)cc1)S(=O)(=O)N1CCN(Cn2c(C)nc3cnccc23)CC1 Show InChI InChI=1S/C29H30FN7O3S/c1-20-32-25-17-31-11-10-26(25)37(20)19-34-12-14-35(15-13-34)41(39,40)28-18-36(29(38)33(2)3)27-16-22(6-9-24(27)28)21-4-7-23(30)8-5-21/h4-11,16-18H,12-15,19H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062084 (4-Ethynyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C#C Show InChI InChI=1S/C28H23N5O2/c1-5-20-7-6-8-25-26(20)22(17-33(25)28(35)31(3)4)27(34)21-11-9-19(10-12-21)16-32-18(2)30-23-15-29-14-13-24(23)32/h1,6-15,17H,16H2,2-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062049 (CHEMBL367964 | [7-(4-Fluoro-phenyl)-1H-indol-3-yl]...) Show SMILES Cc1nc2cnccc2n1Cc1ccc(cc1)C(=O)c1c[nH]c2c(cccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C29H21FN4O/c1-18-33-26-16-31-14-13-27(26)34(18)17-19-5-7-21(8-6-19)29(35)25-15-32-28-23(3-2-4-24(25)28)20-9-11-22(30)12-10-20/h2-16,32H,17H2,1H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062110 (1-Isopropyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(C)C Show InChI InChI=1S/C28H26N4O3/c1-17(2)31-16-22(26-21(28(34)35-4)6-5-7-25(26)31)27(33)20-10-8-19(9-11-20)15-32-18(3)30-23-14-29-13-12-24(23)32/h5-14,16-17H,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062128 (6-Bromo-1-dimethylcarbamoyl-3-[4-(2-methyl-imidazo...) Show SMILES COC(=O)c1cc(Br)cc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C28H24BrN5O4/c1-16-31-22-13-30-10-9-23(22)33(16)14-17-5-7-18(8-6-17)26(35)21-15-34(28(37)32(2)3)24-12-19(29)11-20(25(21)24)27(36)38-4/h5-13,15H,14H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062126 (1-Carbamoyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(N)=O Show InChI InChI=1S/C26H21N5O4/c1-15-29-20-12-28-11-10-21(20)30(15)13-16-6-8-17(9-7-16)24(32)19-14-31(26(27)34)22-5-3-4-18(23(19)22)25(33)35-2/h3-12,14H,13H2,1-2H3,(H2,27,34)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062108 (4-Ethynyl-3-{[3-fluoro-4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c2c(cccc12)C#C Show InChI InChI=1S/C28H24FN5O2/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33/h1,6-14,16,27,35H,15H2,2-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062107 (1-Methylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]pyr...) Show SMILES CNC(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(=O)OC Show InChI InChI=1S/C27H23N5O4/c1-16-30-21-13-29-12-11-22(21)31(16)14-17-7-9-18(10-8-17)25(33)20-15-32(27(35)28-2)23-6-4-5-19(24(20)23)26(34)36-3/h4-13,15H,14H2,1-3H3,(H,28,35)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062081 (3-[4-(2-Methyl-benzoimidazol-1-ylmethyl)-benzoyl]-...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5ccccc45)cc3)c12)C(=O)N1CCCC1 Show InChI InChI=1S/C31H28N4O4/c1-20-32-25-9-3-4-10-26(25)34(20)18-21-12-14-22(15-13-21)29(36)24-19-35(31(38)33-16-5-6-17-33)27-11-7-8-23(28(24)27)30(37)39-2/h3-4,7-15,19H,5-6,16-18H2,1-2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062121 (3-[4-(4-Chloro-2-methyl-imidazo[4,5-c]pyridin-1-yl...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5c(Cl)nccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C28H24ClN5O4/c1-16-31-24-22(12-13-30-26(24)29)33(16)14-17-8-10-18(11-9-17)25(35)20-15-34(28(37)32(2)3)21-7-5-6-19(23(20)21)27(36)38-4/h5-13,15H,14H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062054 (4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c2c(cccc12)C#C Show InChI InChI=1S/C28H22FN5O2/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33/h1,6-14,16H,15H2,2-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The compound was evaluated for its binding affinity against PAF receptor in rabbit platelet				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062095 (4-Methyl-3-{2-[4-(2-methyl-imidazo[4,5-c]pyridin-1...) Show SMILES CN(C)C(=O)n1cc(C(=O)CN2CCC(CC2)n2c(C)nc3cnccc23)c2c(C)cccc12 Show InChI InChI=1S/C26H30N6O2/c1-17-6-5-7-23-25(17)20(15-31(23)26(34)29(3)4)24(33)16-30-12-9-19(10-13-30)32-18(2)28-21-14-27-11-8-22(21)32/h5-8,11,14-15,19H,9-10,12-13,16H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM191 ((5R,6R)-1,2,4,5-tetrabenzyl-6-hydroxy-1,2,4-triaze...) Show SMILES O[C@@H]1CN(Cc2ccccc2)N(Cc2ccccc2)C(=O)N(Cc2ccccc2)[C@@H]1Cc1ccccc1 |r| Show InChI InChI=1S/C32H33N3O2/c36-31-25-33(22-27-15-7-2-8-16-27)35(24-29-19-11-4-12-20-29)32(37)34(23-28-17-9-3-10-18-28)30(31)21-26-13-5-1-6-14-26/h1-20,30-31,36H,21-25H2/t30-,31-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	-50.5	n/a	n/a	n/a	n/a	n/a	4.7	30
Abbott Laboratories					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...				J Med Chem 39: 392-7 (1996) Article DOI: 10.1021/jm9507183 BindingDB Entry DOI: 10.7270/Q2V40SC6
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062042 (4-Methoxy-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...) Show SMILES COc1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C27H25N5O3/c1-17-29-21-14-28-13-12-22(21)31(17)15-18-8-10-19(11-9-18)26(33)20-16-32(27(34)30(2)3)23-6-5-7-24(35-4)25(20)23/h5-14,16H,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062077 (4-Benzoylamino-3-[4-(2-methyl-imidazo[4,5-c]pyridi...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(NC(=O)c3ccccc3)cccc12 Show InChI InChI=1S/C33H28N6O3/c1-21-35-27-18-34-17-16-28(27)38(21)19-22-12-14-23(15-13-22)31(40)25-20-39(33(42)37(2)3)29-11-7-10-26(30(25)29)36-32(41)24-8-5-4-6-9-24/h4-18,20H,19H2,1-3H3,(H,36,41)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062093 ((4-Ethynyl-1H-indol-3-yl)-[3-fluoro-4-(2-methyl-im...) Show SMILES Cc1nc2cnccc2n1Cc1ccc(cc1F)C(=O)c1c[nH]c2cccc(C#C)c12 Show InChI InChI=1S/C25H17FN4O/c1-3-16-5-4-6-21-24(16)19(12-28-21)25(31)17-7-8-18(20(26)11-17)14-30-15(2)29-22-13-27-10-9-23(22)30/h1,4-13,28H,14H2,2H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062112 (6-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2ccc(cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C32H26FN5O2/c1-20-35-28-17-34-15-14-29(28)37(20)18-21-4-6-23(7-5-21)31(39)27-19-38(32(40)36(2)3)30-16-24(10-13-26(27)30)22-8-11-25(33)12-9-22/h4-17,19H,18H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062071 (1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)C3CCC(Cn4c(C)nc5cnccc45)CC3)c12)C(=O)N(C)C |(5.2,-3.63,;5.2,-5.17,;3.88,-5.94,;2.54,-5.18,;3.88,-7.46,;2.55,-8.26,;2.55,-9.82,;3.88,-10.59,;5.23,-9.82,;6.71,-10.3,;7.63,-9.02,;6.71,-7.76,;7.18,-6.29,;6.41,-4.95,;8.71,-6.13,;9.75,-5.41,;11.56,-5.59,;11.95,-4.1,;12.85,-2.85,;14.38,-2.69,;15.47,-3.77,;15.24,-5.3,;16.83,-3.06,;16.57,-1.55,;17.53,-.36,;16.98,1.06,;15.46,1.3,;14.52,.11,;15.06,-1.31,;10.83,-4.82,;9.11,-4.64,;5.23,-8.26,;7.2,-11.75,;6.42,-13.08,;8.72,-11.91,;9.35,-13.31,;9.63,-10.67,)| Show InChI InChI=1S/C28H31N5O4/c1-17-30-22-14-29-13-12-23(22)32(17)15-18-8-10-19(11-9-18)26(34)21-16-33(28(36)31(2)3)24-7-5-6-20(25(21)24)27(35)37-4/h5-7,12-14,16,18-19H,8-11,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062127 (6-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(=O)N2CCC(Cn3c(C)nc4cnccc34)CC2)c2ccc(cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C31H31FN6O2/c1-20-34-27-17-33-13-10-28(27)37(20)18-21-11-14-36(15-12-21)30(39)26-19-38(31(40)35(2)3)29-16-23(6-9-25(26)29)22-4-7-24(32)8-5-22/h4-10,13,16-17,19,21H,11-12,14-15,18H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062125 (3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-b...) Show SMILES COC(=O)c1ccc(C(=O)OC)c2c(c[nH]c12)C(=O)c1ccc(Cn2c(C)nc3cnccc23)cc1 Show InChI InChI=1S/C27H22N4O5/c1-15-30-21-13-28-11-10-22(21)31(15)14-16-4-6-17(7-5-16)25(32)20-12-29-24-19(27(34)36-3)9-8-18(23(20)24)26(33)35-2/h4-13,29H,14H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062067 (4-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C32H26FN5O2/c1-20-35-27-17-34-16-15-28(27)37(20)18-21-7-9-23(10-8-21)31(39)26-19-38(32(40)36(2)3)29-6-4-5-25(30(26)29)22-11-13-24(33)14-12-22/h4-17,19H,18H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062102 (1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-b]p...) Show SMILES COC(=O)c1cccc2n(cc(C(=O)c3ccc(Cn4c(C)nc5ncccc45)cc3)c12)C(=O)N(C)C Show InChI InChI=1S/C28H25N5O4/c1-17-30-26-23(9-6-14-29-26)32(17)15-18-10-12-19(13-11-18)25(34)21-16-33(28(36)31(2)3)22-8-5-7-20(24(21)22)27(35)37-4/h5-14,16H,15H2,1-4H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062052 (4-(4-Fluoro-phenyl)-3-[6-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(=O)CCCCCn2c(C)nc3cnccc23)c2c(cccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C30H30FN5O2/c1-20-33-25-18-32-16-15-26(25)35(20)17-6-4-5-10-28(37)24-19-36(30(38)34(2)3)27-9-7-8-23(29(24)27)21-11-13-22(31)14-12-21/h7-9,11-16,18-19H,4-6,10,17H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50062090 (6-(4-Fluoro-phenyl)-3-[4-(2-methyl-imidazo[4,5-c]p...) Show SMILES CN(C)C(=O)n1cc(C(=O)N2CCC(CC2)n2c(C)nc3cnccc23)c2ccc(cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C30H29FN6O2/c1-19-33-26-17-32-13-10-27(26)37(19)23-11-14-35(15-12-23)29(38)25-18-36(30(39)34(2)3)28-16-21(6-9-24(25)28)20-4-7-22(31)8-5-20/h4-10,13,16-18,23H,11-12,14-15H2,1-3H3	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes				J Med Chem 41: 74-95 (1998) Article DOI: 10.1021/jm970389+ BindingDB Entry DOI: 10.7270/Q2MC8Z4D
					More data for this Ligand-Target Pair

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