Compile Data Set for Download or QSAR

Found 55 hits with Last Name = 'derrick' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50248793 (17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50287928 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(Cl)cc1 |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(34)31-21-11-12-29(35)23-15-19-6-9-22(33)26-25(19)28(29,27(21)36-26)13-14-32(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,31,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50287927 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31N3O6/c33-22-9-6-19-15-23-29(35)12-11-21(30-24(34)10-5-17-3-7-20(8-4-17)32(36)37)27-28(29,25(19)26(22)38-27)13-14-31(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,30,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287928 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(Cl)cc1 |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(34)31-21-11-12-29(35)23-15-19-6-9-22(33)26-25(19)28(29,27(21)36-26)13-14-32(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,31,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50248793 (17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398951 (CHEMBL2179258) Show SMILES COC(=O)\C=C\C(=O)O[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O |r| Show InChI InChI=1S/C25H27NO7/c1-31-19(29)6-7-20(30)33-25-9-8-17(28)23-24(25)10-11-26(13-14-2-3-14)18(25)12-15-4-5-16(27)22(32-23)21(15)24/h4-7,14,18,23,27H,2-3,8-13H2,1H3/b7-6+/t18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50287929 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Cc1ccc(\C=C\C(=O)N[C@@H]2CC[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H]2C3(CCN4CC2CC2)c56)cc1 |TLB:29:28:13:33.17.16| Show InChI InChI=1S/C30H34N2O4/c1-18-2-4-19(5-3-18)8-11-25(34)31-22-12-13-30(35)24-16-21-9-10-23(33)27-26(21)29(30,28(22)36-27)14-15-32(24)17-20-6-7-20/h2-5,8-11,20,22,24,28,33,35H,6-7,12-17H2,1H3,(H,31,34)/b11-8+/t22-,24-,28+,29?,30-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398952 (CHEMBL2179264) Show SMILES COC(=O)\C=C\C(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O |r| Show InChI InChI=1S/C25H28N2O6/c1-32-20(31)7-6-19(30)26-25-9-8-17(29)23-24(25)10-11-27(13-14-2-3-14)18(25)12-15-4-5-16(28)22(33-23)21(15)24/h4-7,14,18,23,28H,2-3,8-13H2,1H3,(H,26,30)/b7-6+/t18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50247803 (Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...) Show SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50247803 (Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...) Show SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50091405 (1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(Cl)cc1)ccc3OC |r| Show InChI InChI=1S/C30H31ClN2O4/c1-36-23-10-7-20-16-24-30(32-25(35)11-6-18-4-8-21(31)9-5-18)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-19-2-3-19/h4-11,19,24,28H,2-3,12-17H2,1H3,(H,32,35)/b11-6+/t24?,28?,29-,30?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranes				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50091405 (1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(Cl)cc1)ccc3OC |r| Show InChI InChI=1S/C30H31ClN2O4/c1-36-23-10-7-20-16-24-30(32-25(35)11-6-18-4-8-21(31)9-5-18)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-19-2-3-19/h4-11,19,24,28H,2-3,12-17H2,1H3,(H,32,35)/b11-6+/t24?,28?,29-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranes				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398950 (CHEMBL2179259) Show SMILES COC(=O)CCC(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(31)7-6-19(30)26-25-9-8-17(29)23-24(25)10-11-27(13-14-2-3-14)18(25)12-15-4-5-16(28)22(33-23)21(15)24/h4-5,14,18,23,28H,2-3,6-13H2,1H3,(H,26,30)/t18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398952 (CHEMBL2179264) Show SMILES COC(=O)\C=C\C(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O |r| Show InChI InChI=1S/C25H28N2O6/c1-32-20(31)7-6-19(30)26-25-9-8-17(29)23-24(25)10-11-27(13-14-2-3-14)18(25)12-15-4-5-16(28)22(33-23)21(15)24/h4-7,14,18,23,28H,2-3,8-13H2,1H3,(H,26,30)/b7-6+/t18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50091404 (1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...) Show SMILES Clc1ccc(\C=C\C(=O)NC23CCC(=O)C4Oc5cccc6CC2N(CC2CC2)CC[C@@]34c56)cc1 |THB:17:32:10:24.30.29,20:21:10:24.30.29| Show InChI InChI=1S/C29H29ClN2O3/c30-21-9-6-18(7-10-21)8-11-25(34)31-29-13-12-22(33)27-28(29)14-15-32(17-19-4-5-19)24(29)16-20-2-1-3-23(35-27)26(20)28/h1-3,6-11,19,24,27H,4-5,12-17H2,(H,31,34)/b11-8+/t24?,27?,28-,29?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranes range; Value ranges from (0.32-0.91)				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287929 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Cc1ccc(\C=C\C(=O)N[C@@H]2CC[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H]2C3(CCN4CC2CC2)c56)cc1 |TLB:29:28:13:33.17.16| Show InChI InChI=1S/C30H34N2O4/c1-18-2-4-19(5-3-18)8-11-25(34)31-22-12-13-30(35)24-16-21-9-10-23(33)27-26(21)29(30,28(22)36-27)14-15-32(24)17-20-6-7-20/h2-5,8-11,20,22,24,28,33,35H,6-7,12-17H2,1H3,(H,31,34)/b11-8+/t22-,24-,28+,29?,30-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398950 (CHEMBL2179259) Show SMILES COC(=O)CCC(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(31)7-6-19(30)26-25-9-8-17(29)23-24(25)10-11-27(13-14-2-3-14)18(25)12-15-4-5-16(28)22(33-23)21(15)24/h4-5,14,18,23,28H,2-3,6-13H2,1H3,(H,26,30)/t18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398946 (CHEMBL2179263) Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1CNC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,THB:8:7:30.29:3.4| Show InChI InChI=1S/C33H38N2O4/c1-38-33-14-13-31(18-24(33)19-34-27(37)12-9-21-5-3-2-4-6-21)26-17-23-10-11-25(36)29-28(23)32(31,30(33)39-29)15-16-35(26)20-22-7-8-22/h2-6,9-12,22,24,26,30,36H,7-8,13-20H2,1H3,(H,34,37)/b12-9+/t24-,26-,30-,31-,32+,33-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287927 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31N3O6/c33-22-9-6-19-15-23-29(35)12-11-21(30-24(34)10-5-17-3-7-20(8-4-17)32(36)37)27-28(29,25(19)26(22)38-27)13-14-31(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,30,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398951 (CHEMBL2179258) Show SMILES COC(=O)\C=C\C(=O)O[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O |r| Show InChI InChI=1S/C25H27NO7/c1-31-19(29)6-7-20(30)33-25-9-8-17(28)23-24(25)10-11-26(13-14-2-3-14)18(25)12-15-4-5-16(27)22(32-23)21(15)24/h4-7,14,18,23,27H,2-3,8-13H2,1H3/b7-6+/t18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398948 (CHEMBL2179261) Show SMILES COC(=O)\C=C\C(=O)NC[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O |r,THB:9:10:32.18:14.13| Show InChI InChI=1S/C29H36N2O6/c1-35-23(34)8-7-22(33)30-15-19-14-27-9-10-29(19,36-2)26-28(27)11-12-31(16-17-3-4-17)21(27)13-18-5-6-20(32)25(37-26)24(18)28/h5-8,17,19,21,26,32H,3-4,9-16H2,1-2H3,(H,30,33)/b8-7+/t19-,21-,26-,27-,28+,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398947 (CHEMBL2179262) Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1NC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,THB:8:7:29.28:3.4| Show InChI InChI=1S/C32H36N2O4/c1-37-32-14-13-30(18-24(32)33-26(36)12-9-20-5-3-2-4-6-20)25-17-22-10-11-23(35)28-27(22)31(30,29(32)38-28)15-16-34(25)19-21-7-8-21/h2-6,9-12,21,24-25,29,35H,7-8,13-19H2,1H3,(H,33,36)/b12-9+/t24-,25+,29+,30+,31-,32+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50247803 (Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...) Show SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50247803 (Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...) Show SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50354578 (BUPRENORPHINE | US10752592, Compound buprenorphine...) Show SMILES CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r| Show InChI InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398947 (CHEMBL2179262) Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1NC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,THB:8:7:29.28:3.4| Show InChI InChI=1S/C32H36N2O4/c1-37-32-14-13-30(18-24(32)33-26(36)12-9-20-5-3-2-4-6-20)25-17-22-10-11-23(35)28-27(22)31(30,29(32)38-28)15-16-34(25)19-21-7-8-21/h2-6,9-12,21,24-25,29,35H,7-8,13-19H2,1H3,(H,33,36)/b12-9+/t24-,25+,29+,30+,31-,32+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50354578 (BUPRENORPHINE | US10752592, Compound buprenorphine...) Show SMILES CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r| Show InChI InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50066535 ((2E)-3-(4-chlorophenyl)-N-[(1R,13R,17S)-4-(cyclopr...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(Cl)cc1)ccc3O |r,THB:10:9:17:6.5.4| Show InChI InChI=1S/C29H29ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(35)31-29-12-11-22(34)27-28(29)13-14-32(16-18-1-2-18)23(29)15-19-6-9-21(33)26(36-27)25(19)28/h3-10,18,23,27,33H,1-2,11-16H2,(H,31,35)/b10-5+/t23?,27-,28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranes				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50066535 ((2E)-3-(4-chlorophenyl)-N-[(1R,13R,17S)-4-(cyclopr...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(Cl)cc1)ccc3O |r,THB:10:9:17:6.5.4| Show InChI InChI=1S/C29H29ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(35)31-29-12-11-22(34)27-28(29)13-14-32(16-18-1-2-18)23(29)15-19-6-9-21(33)26(36-27)25(19)28/h3-10,18,23,27,33H,1-2,11-16H2,(H,31,35)/b10-5+/t23?,27-,28-,29+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranes				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50066535 ((2E)-3-(4-chlorophenyl)-N-[(1R,13R,17S)-4-(cyclopr...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(Cl)cc1)ccc3O |r,THB:10:9:17:6.5.4| Show InChI InChI=1S/C29H29ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(35)31-29-12-11-22(34)27-28(29)13-14-32(16-18-1-2-18)23(29)15-19-6-9-21(33)26(36-27)25(19)28/h3-10,18,23,27,33H,1-2,11-16H2,(H,31,35)/b10-5+/t23?,27-,28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranes				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398949 (CHEMBL2179260) Show SMILES COC(=O)\C=C\C(=O)N[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O |r,THB:8:9:31.17:13.12| Show InChI InChI=1S/C28H34N2O6/c1-34-22(33)8-7-21(32)29-19-14-26-9-10-28(19,35-2)25-27(26)11-12-30(15-16-3-4-16)20(26)13-17-5-6-18(31)24(36-25)23(17)27/h5-8,16,19-20,25,31H,3-4,9-15H2,1-2H3,(H,29,32)/b8-7+/t19-,20+,25+,26+,27-,28+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398946 (CHEMBL2179263) Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1CNC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,THB:8:7:30.29:3.4| Show InChI InChI=1S/C33H38N2O4/c1-38-33-14-13-31(18-24(33)19-34-27(37)12-9-21-5-3-2-4-6-21)26-17-23-10-11-25(36)29-28(23)32(31,30(33)39-29)15-16-35(26)20-22-7-8-22/h2-6,9-12,22,24,26,30,36H,7-8,13-20H2,1H3,(H,34,37)/b12-9+/t24-,26-,30-,31-,32+,33-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50398948 (CHEMBL2179261) Show SMILES COC(=O)\C=C\C(=O)NC[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O |r,THB:9:10:32.18:14.13| Show InChI InChI=1S/C29H36N2O6/c1-35-23(34)8-7-22(33)30-15-19-14-27-9-10-29(19,36-2)26-28(27)11-12-31(16-17-3-4-17)21(27)13-18-5-6-20(32)25(37-26)24(18)28/h5-8,17,19,21,26,32H,3-4,9-16H2,1-2H3,(H,30,33)/b8-7+/t19-,21-,26-,27-,28+,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from KOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50398949 (CHEMBL2179260) Show SMILES COC(=O)\C=C\C(=O)N[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O |r,THB:8:9:31.17:13.12| Show InChI InChI=1S/C28H34N2O6/c1-34-22(33)8-7-21(32)29-19-14-26-9-10-28(19,35-2)25-27(26)11-12-30(15-16-3-4-16)20(26)13-17-5-6-18(31)24(36-25)23(17)27/h5-8,16,19-20,25,31H,3-4,9-15H2,1-2H3,(H,29,32)/b8-7+/t19-,20+,25+,26+,27-,28+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from MOR in guinea pig brain membrane				J Med Chem 55: 9868-74 (2012) Article DOI: 10.1021/jm301096s BindingDB Entry DOI: 10.7270/Q2M909TS
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50248793 (17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50091405 (1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)NC(=O)\C=C\c1ccc(Cl)cc1)ccc3OC |r| Show InChI InChI=1S/C30H31ClN2O4/c1-36-23-10-7-20-16-24-30(32-25(35)11-6-18-4-8-21(31)9-5-18)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-19-2-3-19/h4-11,19,24,28H,2-3,12-17H2,1H3,(H,32,35)/b11-6+/t24?,28?,29-,30?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranes				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50287928 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(Cl)cc1 |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(34)31-21-11-12-29(35)23-15-19-6-9-22(33)26-25(19)28(29,27(21)36-26)13-14-32(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,31,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50287927 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31N3O6/c33-22-9-6-19-15-23-29(35)12-11-21(30-24(34)10-5-17-3-7-20(8-4-17)32(36)37)27-28(29,25(19)26(22)38-27)13-14-31(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,30,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50287929 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Cc1ccc(\C=C\C(=O)N[C@@H]2CC[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H]2C3(CCN4CC2CC2)c56)cc1 |TLB:29:28:13:33.17.16| Show InChI InChI=1S/C30H34N2O4/c1-18-2-4-19(5-3-18)8-11-25(34)31-22-12-13-30(35)24-16-21-9-10-23(33)27-26(21)29(30,28(22)36-27)14-15-32(24)17-20-6-7-20/h2-5,8-11,20,22,24,28,33,35H,6-7,12-17H2,1H3,(H,31,34)/b11-8+/t22-,24-,28+,29?,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50091404 (1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...) Show SMILES Clc1ccc(\C=C\C(=O)NC23CCC(=O)C4Oc5cccc6CC2N(CC2CC2)CC[C@@]34c56)cc1 |THB:17:32:10:24.30.29,20:21:10:24.30.29| Show InChI InChI=1S/C29H29ClN2O3/c30-21-9-6-18(7-10-21)8-11-25(34)31-29-13-12-22(33)27-28(29)14-15-32(17-19-4-5-19)24(29)16-20-2-1-3-23(35-27)26(20)28/h1-3,6-11,19,24,27H,4-5,12-17H2,(H,31,34)/b11-8+/t24?,27?,28-,29?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranes range; Value ranges from (9.7-14.2)				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50248793 (17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileum				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50247803 (Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...) Show SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287927 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31N3O6/c33-22-9-6-19-15-23-29(35)12-11-21(30-24(34)10-5-17-3-7-20(8-4-17)32(36)37)27-28(29,25(19)26(22)38-27)13-14-31(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,30,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50091404 (1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...) Show SMILES Clc1ccc(\C=C\C(=O)NC23CCC(=O)C4Oc5cccc6CC2N(CC2CC2)CC[C@@]34c56)cc1 |THB:17:32:10:24.30.29,20:21:10:24.30.29| Show InChI InChI=1S/C29H29ClN2O3/c30-21-9-6-18(7-10-21)8-11-25(34)31-29-13-12-22(33)27-28(29)14-15-32(17-19-4-5-19)24(29)16-20-2-1-3-23(35-27)26(20)28/h1-3,6-11,19,24,27H,4-5,12-17H2,(H,31,34)/b11-8+/t24?,27?,28-,29?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranes range; Value ranges from (34.0-43.2)				J Med Chem 43: 3348-50 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66R0
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287928 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(Cl)cc1 |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(34)31-21-11-12-29(35)23-15-19-6-9-22(33)26-25(19)28(29,27(21)36-26)13-14-32(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,31,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50247803 (Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...) Show SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 |r| Show InChI InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileum				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287929 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Cc1ccc(\C=C\C(=O)N[C@@H]2CC[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H]2C3(CCN4CC2CC2)c56)cc1 |TLB:29:28:13:33.17.16| Show InChI InChI=1S/C30H34N2O4/c1-18-2-4-19(5-3-18)8-11-25(34)31-22-12-13-30(35)24-16-21-9-10-23(33)27-26(21)29(30,28(22)36-27)14-15-32(24)17-20-6-7-20/h2-5,8-11,20,22,24,28,33,35H,6-7,12-17H2,1H3,(H,31,34)/b11-8+/t22-,24-,28+,29?,30-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	171	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50248793 (17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileum				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50287928 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(Cl)cc1 |THB:8:7:22:18.4.5| Show InChI InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(34)31-21-11-12-29(35)23-15-19-6-9-22(33)26-25(19)28(29,27(21)36-26)13-14-32(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,31,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Mus musculus (Mouse))	BDBM50248793 (17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for kappa opioid receptor mediated agonistic effect in mouse vas deferens(MVD) preparations				Bioorg Med Chem Lett 6: 167-172 (1996) Article DOI: 10.1016/0960-894X(95)00583-F BindingDB Entry DOI: 10.7270/Q2QJ7H83
					More data for this Ligand-Target Pair

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