Found 91 hits with Last Name = 'dhanani' and Initial = 's' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296974
(4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...)Show InChI InChI=1S/C16H13IN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 65.1 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50188097
(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)Show InChI InChI=1S/C10H9ClN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of aromatase |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296973
(4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...)Show InChI InChI=1S/C16H13BrN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70.4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296970
(4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...)Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C16H13N3O5S/c20-19(21)14-3-7-16(8-4-14)25(22,23)24-15-5-1-13(2-6-15)11-18-10-9-17-12-18/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296972
(4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...)Show InChI InChI=1S/C16H13ClN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98.7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296975
(4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...)Show InChI InChI=1S/C17H16N2O4S/c1-22-15-6-8-17(9-7-15)24(20,21)23-16-4-2-14(3-5-16)12-19-11-10-18-13-19/h2-11,13H,12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50188093
(1-(4-Nitro-benzyl)-1H-imidazole | 1-(4-nitrobenzyl...)Show InChI InChI=1S/C10H9N3O2/c14-13(15)10-3-1-9(2-4-10)7-12-6-5-11-8-12/h1-6,8H,7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of aromatase |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296971
(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)Show InChI InChI=1S/C16H13FN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296969
(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)Show InChI InChI=1S/C17H16N2O3S/c1-14-2-8-17(9-3-14)23(20,21)22-16-6-4-15(5-7-16)12-19-11-10-18-13-19/h2-11,13H,12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296976
(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)14-3-7-16(8-4-14)26(23,24)25-15-5-1-13(2-6-15)11-22-10-9-21-12-22/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 291 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191795
(CHEMBL386256 | N-3-(4-bromophenyl)propyl imidazole)Show InChI InChI=1S/C12H13BrN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191792
(1-(3-(4-chlorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13ClN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50188085
(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)Show InChI InChI=1S/C10H9FN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of aromatase |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50008733
(1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...)Show InChI InChI=1S/C11H9N3/c12-7-10-1-3-11(4-2-10)8-14-6-5-13-9-14/h1-6,9H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of aromatase |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188092
(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)Show InChI InChI=1S/C10H9IN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188092
(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)Show InChI InChI=1S/C10H9IN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191794
(1-(3-(4-fluorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13FN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188095
(1-(3,4-Dichloro-benzyl)-1H-imidazole | 1-(3,4-dich...)Show InChI InChI=1S/C10H8Cl2N2/c11-9-2-1-8(5-10(9)12)6-14-4-3-13-7-14/h1-5,7H,6H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188097
(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)Show InChI InChI=1S/C10H9ClN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188088
(1-(4-bromobenzyl)-1H-imidazole | CHEMBL211207)Show InChI InChI=1S/C10H9BrN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50189963
(1-(4-hydroxyphenyl)nonan-1-one | CHEMBL213237)Show InChI InChI=1S/C15H22O2/c1-2-3-4-5-6-7-8-15(17)13-9-11-14(16)12-10-13/h9-12,16H,2-8H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 4519-22 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.029 BindingDB Entry DOI: 10.7270/Q2D21X7Q |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191795
(CHEMBL386256 | N-3-(4-bromophenyl)propyl imidazole)Show InChI InChI=1S/C12H13BrN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188091
(1-(3,5-dibromobenzyl)-1H-imidazole | CHEMBL211276)Show InChI InChI=1S/C10H8Br2N2/c11-9-3-8(4-10(12)5-9)6-14-2-1-13-7-14/h1-5,7H,6H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188094
(1-(3,5-dichlorobenzyl)-1H-imidazole | CHEMBL210125)Show InChI InChI=1S/C10H8Cl2N2/c11-9-3-8(4-10(12)5-9)6-14-2-1-13-7-14/h1-5,7H,6H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296973
(4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...)Show InChI InChI=1S/C16H13BrN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188097
(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)Show InChI InChI=1S/C10H9ClN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50189961
(1-(4-hydroxyphenyl)decan-1-one | CHEMBL214141)Show InChI InChI=1S/C16H24O2/c1-2-3-4-5-6-7-8-9-16(18)14-10-12-15(17)13-11-14/h10-13,17H,2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 4519-22 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.029 BindingDB Entry DOI: 10.7270/Q2D21X7Q |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191792
(1-(3-(4-chlorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13ClN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 5.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296975
(4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...)Show InChI InChI=1S/C17H16N2O4S/c1-22-15-6-8-17(9-7-15)24(20,21)23-16-4-2-14(3-5-16)12-19-11-10-18-13-19/h2-11,13H,12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191796
(1-(3-phenylpropyl)-1H-imidazole | CHEMBL380271)Show InChI InChI=1S/C12H14N2/c1-2-5-12(6-3-1)7-4-9-14-10-8-13-11-14/h1-3,5-6,8,10-11H,4,7,9H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50189956
(1-(4-hydroxyphenyl)octan-1-one | CHEMBL213038)Show InChI InChI=1S/C14H20O2/c1-2-3-4-5-6-7-14(16)12-8-10-13(15)11-9-12/h8-11,15H,2-7H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 4519-22 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.029 BindingDB Entry DOI: 10.7270/Q2D21X7Q |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188088
(1-(4-bromobenzyl)-1H-imidazole | CHEMBL211207)Show InChI InChI=1S/C10H9BrN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296972
(4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...)Show InChI InChI=1S/C16H13ClN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296970
(4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...)Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Oc1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C16H13N3O5S/c20-19(21)14-3-7-16(8-4-14)25(22,23)24-15-5-1-13(2-6-15)11-18-10-9-17-12-18/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188093
(1-(4-Nitro-benzyl)-1H-imidazole | 1-(4-nitrobenzyl...)Show InChI InChI=1S/C10H9N3O2/c14-13(15)10-3-1-9(2-4-10)7-12-6-5-11-8-12/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50189962
(1-(4-hydroxyphenyl)dodecan-1-one | CHEMBL214017)Show InChI InChI=1S/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-18(20)16-12-14-17(19)15-13-16/h12-15,19H,2-11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 4519-22 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.029 BindingDB Entry DOI: 10.7270/Q2D21X7Q |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50008733
(1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...)Show InChI InChI=1S/C11H9N3/c12-7-10-1-3-11(4-2-10)8-14-6-5-13-9-14/h1-6,9H,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50189958
(1-(4-hydroxyphenyl)heptan-1-one | CHEMBL213954)Show InChI InChI=1S/C13H18O2/c1-2-3-4-5-6-13(15)11-7-9-12(14)10-8-11/h7-10,14H,2-6H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 4519-22 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.029 BindingDB Entry DOI: 10.7270/Q2D21X7Q |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188086
(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)Show InChI InChI=1S/C10H10N2O/c13-10-3-1-9(2-4-10)7-12-6-5-11-8-12/h1-6,8,13H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188087
(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)Show InChI InChI=1S/C11H12N2/c1-10-2-4-11(5-3-10)8-13-7-6-12-9-13/h2-7,9H,8H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188090
(1-(3,4-difluorobenzyl)-1H-imidazole | CHEMBL373588)Show InChI InChI=1S/C10H8F2N2/c11-9-2-1-8(5-10(9)12)6-14-4-3-13-7-14/h1-5,7H,6H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50296974
(4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...)Show InChI InChI=1S/C16H13IN2O3S/c17-14-3-7-16(8-4-14)23(20,21)22-15-5-1-13(2-6-15)11-19-10-9-18-12-19/h1-10,12H,11H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188092
(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)Show InChI InChI=1S/C10H9IN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland
Curated by ChEMBL
| Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha |
Bioorg Med Chem Lett 19: 4698-701 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188092
(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)Show InChI InChI=1S/C10H9IN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4011-5 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 |
More data for this Ligand-Target Pair | |