Compile Data Set for Download or QSAR

Found 253 hits with Last Name = 'dhanoa' and Initial = 'ds'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187394 (CHEMBL207220 | N-(3-{4-[4-(cyclohexylmethanesulfon...) Show SMILES CN(CCCCN1CCN(CC1)c1cccc(NC(C)=O)c1)S(=O)(=O)CC1CCCCC1 Show InChI InChI=1S/C24H40N4O3S/c1-21(29)25-23-11-8-12-24(19-23)28-17-15-27(16-18-28)14-7-6-13-26(2)32(30,31)20-22-9-4-3-5-10-22/h8,11-12,19,22H,3-7,9-10,13-18,20H2,1-2H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187377 (CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50005127 (1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187387 (CHEMBL210537 | N-(3-(4-(4-(4-methylphenylsulfonami...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H32N4O3S/c1-19-8-10-23(11-9-19)31(29,30)24-12-3-4-13-26-14-16-27(17-15-26)22-7-5-6-21(18-22)25-20(2)28/h5-11,18,24H,3-4,12-17H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187389 (CHEMBL377697 | cyclopropanecarboxylic acid {3-[4-(...) Show SMILES O=C(Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1)C1CC1 Show InChI InChI=1S/C25H40N4O3S/c30-25(22-11-12-22)27-23-9-6-10-24(19-23)29-17-15-28(16-18-29)14-5-4-13-26-33(31,32)20-21-7-2-1-3-8-21/h6,9-10,19,21-22,26H,1-5,7-8,11-18,20H2,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187379 (CHEMBL379984 | N-(3-{4-[4-(2-methyl-propane-1-sulf...) Show SMILES CC(C)CS(=O)(=O)NCCCCN1CCN(CC1)c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C20H34N4O3S/c1-17(2)16-28(26,27)21-9-4-5-10-23-11-13-24(14-12-23)20-8-6-7-19(15-20)22-18(3)25/h6-8,15,17,21H,4-5,9-14,16H2,1-3H3,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187383 (CHEMBL207478 | N-[3-(4-{4-[methyl-(2-methyl-propan...) Show SMILES CC(C)CS(=O)(=O)N(C)CCCCN1CCN(CC1)c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C21H36N4O3S/c1-18(2)17-29(27,28)23(4)10-5-6-11-24-12-14-25(15-13-24)21-9-7-8-20(16-21)22-19(3)26/h7-9,16,18H,5-6,10-15,17H2,1-4H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187385 (CHEMBL211012 | N-{3-[4-(1-Cyclohexylmethanesulfony...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CC2CCN(CC2)S(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C25H40N4O3S/c1-21(30)26-24-8-5-9-25(18-24)28-16-14-27(15-17-28)19-22-10-12-29(13-11-22)33(31,32)20-23-6-3-2-4-7-23/h5,8-9,18,22-23H,2-4,6-7,10-17,19-20H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465] (Rattus norvegicus (rat))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]RX 821002 from Adrenergic alpha-2a receptor in rat cerebral cortex cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to D2 receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187376 (CHEMBL210874 | N-(3-(4-((1-(4-fluorophenylsulfonyl...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CC2CCN(CC2)S(=O)(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C24H31FN4O3S/c1-19(30)26-22-3-2-4-23(17-22)28-15-13-27(14-16-28)18-20-9-11-29(12-10-20)33(31,32)24-7-5-21(25)6-8-24/h2-8,17,20H,9-16,18H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C1 Show InChI InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50187377 (CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat cerebral cortex by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187393 (CHEMBL210795 | N-(3-{4-[4-(4-fluoro-benzenesulfony...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H29FN4O3S/c1-18(28)25-20-5-4-6-21(17-20)27-15-13-26(14-16-27)12-3-2-11-24-31(29,30)22-9-7-19(23)8-10-22/h4-10,17,24H,2-3,11-16H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 2 (Mus musculus)	BDBM50403726 (CHEMBL2112936) Show SMILES N[C@H]1CCCC[C@@H]1NC(=O)c1c2N[C@@H]3CCCC[C@H]3Nc2c2C(=O)c3ccccc3-c3ncnc1c23 Show InChI InChI=1S/C28H30N6O2/c29-16-9-3-4-10-17(16)34-28(36)22-24-20-21(25-26(22)33-19-12-6-5-11-18(19)32-25)27(35)15-8-2-1-7-14(15)23(20)30-13-31-24/h1-2,7-8,13,16-19,32-33H,3-6,9-12,29H2,(H,34,36)/t16-,17-,18+,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 2 beta				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187378 (CHEMBL209459 | cyclopropanecarboxylic acid (3-{4-[...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1cccc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C25H34N4O3S/c1-20-7-11-24(12-8-20)33(31,32)26-13-2-3-14-28-15-17-29(18-16-28)23-6-4-5-22(19-23)27-25(30)21-9-10-21/h4-8,11-12,19,21,26H,2-3,9-10,13-18H2,1H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187388 (CHEMBL209985 | N-(3-{4-[4-(propane-2-sulfonylamino...) Show SMILES CC(C)S(=O)(=O)NCCCCN1CCN(CC1)c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C19H32N4O3S/c1-16(2)27(25,26)20-9-4-5-10-22-11-13-23(14-12-22)19-8-6-7-18(15-19)21-17(3)24/h6-8,15-16,20H,4-5,9-14H2,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to 5HT7 receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50187390 (CHEMBL380369 | Sunepitron) Show SMILES [H][C@@]12CC[C@H](CN3C(=O)CCC3=O)CN1CCN(C2)c1ncccn1 Show InChI InChI=1S/C17H23N5O2/c23-15-4-5-16(24)22(15)11-13-2-3-14-12-21(9-8-20(14)10-13)17-18-6-1-7-19-17/h1,6-7,13-14H,2-5,8-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187397 (CHEMBL266832 | N-(3-(4-(4-(cyclohexylsulfonylamino...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)C2CCCCC2)CC1 Show InChI InChI=1S/C22H36N4O3S/c1-19(27)24-20-8-7-9-21(18-20)26-16-14-25(15-17-26)13-6-5-12-23-30(28,29)22-10-3-2-4-11-22/h7-9,18,22-23H,2-6,10-17H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187380 (4-methyl-N-(4-(4-phenylpiperazin-1-yl)butyl)benzen...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H29N3O2S/c1-19-9-11-21(12-10-19)27(25,26)22-13-5-6-14-23-15-17-24(18-16-23)20-7-3-2-4-8-20/h2-4,7-12,22H,5-6,13-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 2 (Mus musculus)	BDBM50075917 (8N-(2-aminoethyl)-15-oxo-9a,10,11,12,13,13a,14,15-...) Show SMILES NCCNC(=O)c1c2N[C@@H]3CCCC[C@H]3N=c2c2c(O)c3ccccc3c3ncnc1c23 |c:16| Show InChI InChI=1S/C24H24N6O2/c25-9-10-26-24(32)18-20-16-17(21-22(18)30-15-8-4-3-7-14(15)29-21)23(31)13-6-2-1-5-12(13)19(16)27-11-28-20/h1-2,5-6,11,14-15,30-31H,3-4,7-10,25H2,(H,26,32)/t14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 2 beta				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187395 (CHEMBL205550 | N-{4-[4-(3-methanesulfonylamino-phe...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1cccc(NS(C)(=O)=O)c1 Show InChI InChI=1S/C22H32N4O4S2/c1-19-8-10-22(11-9-19)32(29,30)23-12-3-4-13-25-14-16-26(17-15-25)21-7-5-6-20(18-21)24-31(2,27)28/h5-11,18,23-24H,3-4,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187396 (4-methyl-N-(4-{4-[3-(propane-2-sulfonylamino)-phen...) Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H36N4O4S2/c1-20(2)33(29,30)26-22-7-6-8-23(19-22)28-17-15-27(16-18-28)14-5-4-13-25-34(31,32)24-11-9-21(3)10-12-24/h6-12,19-20,25-26H,4-5,13-18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to 5HT2B receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187398 (CHEMBL445928 | N-(3-{4-[4-(toluene-4-sulfonylamino...) Show SMILES CCCC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C25H36N4O3S/c1-3-7-25(30)27-22-8-6-9-23(20-22)29-18-16-28(17-19-29)15-5-4-14-26-33(31,32)24-12-10-21(2)11-13-24/h6,8-13,20,26H,3-5,7,14-19H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C1 Show InChI InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to D2 receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 2 (Mus musculus)	BDBM50403725 (CHEMBL2112326) Show SMILES NCCNC(=O)c1c2N[C@H]3CCCC[C@@H]3Nc2c2C(=O)c3ccccc3-c3ncnc1c23 Show InChI InChI=1S/C24H24N6O2/c25-9-10-26-24(32)18-20-16-17(21-22(18)30-15-8-4-3-7-14(15)29-21)23(31)13-6-2-1-5-12(13)19(16)27-11-28-20/h1-2,5-6,11,14-15,29-30H,3-4,7-10,25H2,(H,26,32)/t14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 2 beta				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187391 (CHEMBL379364 | N-(3-{4-[4-(toluene-4-sulfonylamino...) Show SMILES CC(C)C(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C25H36N4O3S/c1-20(2)25(30)27-22-7-6-8-23(19-22)29-17-15-28(16-18-29)14-5-4-13-26-33(31,32)24-11-9-21(3)10-12-24/h6-12,19-20,26H,4-5,13-18H2,1-3H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 2 (Mus musculus)	BDBM50075918 (8N-[2-amino-(1R,2R)-cyclohexyl]-15-oxo-(9aS,13aS)-...) Show SMILES N[C@@H]1CCCC[C@H]1NC(=O)c1c2N[C@H]3CCCC[C@@H]3N=c2c2c(O)c3ccccc3c3ncnc1c23 |c:21| Show InChI InChI=1S/C28H30N6O2/c29-16-9-3-4-10-17(16)34-28(36)22-24-20-21(25-26(22)33-19-12-6-5-11-18(19)32-25)27(35)15-8-2-1-7-14(15)23(20)30-13-31-24/h1-2,7-8,13,16-19,33,35H,3-6,9-12,29H2,(H,34,36)/t16-,17-,18+,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 2 beta				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187390 (CHEMBL380369 | Sunepitron) Show SMILES [H][C@@]12CC[C@H](CN3C(=O)CCC3=O)CN1CCN(C2)c1ncccn1 Show InChI InChI=1S/C17H23N5O2/c23-15-4-5-16(24)22(15)11-13-2-3-14-12-21(9-8-20(14)10-13)17-18-6-1-7-19-17/h1,6-7,13-14H,2-5,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50187377 (CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to guinea pig sigma receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50005127 (1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to D2 receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50403726 (CHEMBL2112936) Show SMILES N[C@H]1CCCC[C@@H]1NC(=O)c1c2N[C@@H]3CCCC[C@H]3Nc2c2C(=O)c3ccccc3-c3ncnc1c23 Show InChI InChI=1S/C28H30N6O2/c29-16-9-3-4-10-17(16)34-28(36)22-24-20-21(25-26(22)33-19-12-6-5-11-18(19)32-25)27(35)15-8-2-1-7-14(15)23(20)30-13-31-24/h1-2,7-8,13,16-19,32-33H,3-6,9-12,29H2,(H,34,36)/t16-,17-,18+,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187386 (CHEMBL384677 | N-(3-{4-[1-(propane-2-sulfonyl)-pip...) Show SMILES CC(C)S(=O)(=O)N1CCC(CN2CCN(CC2)c2cccc(NC(C)=O)c2)CC1 Show InChI InChI=1S/C21H34N4O3S/c1-17(2)29(27,28)25-9-7-19(8-10-25)16-23-11-13-24(14-12-23)21-6-4-5-20(15-21)22-18(3)26/h4-6,15,17,19H,7-14,16H2,1-3H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187392 (CHEMBL426318 | N-{4-[4-(3-ethanesulfonylamino-phen...) Show SMILES CCS(=O)(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H34N4O4S2/c1-3-32(28,29)25-21-7-6-8-22(19-21)27-17-15-26(16-18-27)14-5-4-13-24-33(30,31)23-11-9-20(2)10-12-23/h6-12,19,24-25H,3-5,13-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50075917 (8N-(2-aminoethyl)-15-oxo-9a,10,11,12,13,13a,14,15-...) Show SMILES NCCNC(=O)c1c2N[C@@H]3CCCC[C@H]3N=c2c2c(O)c3ccccc3c3ncnc1c23 |c:16| Show InChI InChI=1S/C24H24N6O2/c25-9-10-26-24(32)18-20-16-17(21-22(18)30-15-8-4-3-7-14(15)29-21)23(31)13-6-2-1-5-12(13)19(16)27-11-28-20/h1-2,5-6,11,14-15,30-31H,3-4,7-10,25H2,(H,26,32)/t14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50075918 (8N-[2-amino-(1R,2R)-cyclohexyl]-15-oxo-(9aS,13aS)-...) Show SMILES N[C@@H]1CCCC[C@H]1NC(=O)c1c2N[C@H]3CCCC[C@@H]3N=c2c2c(O)c3ccccc3c3ncnc1c23 |c:21| Show InChI InChI=1S/C28H30N6O2/c29-16-9-3-4-10-17(16)34-28(36)22-24-20-21(25-26(22)33-19-12-6-5-11-18(19)32-25)27(35)15-8-2-1-7-14(15)23(20)30-13-31-24/h1-2,7-8,13,16-19,33,35H,3-6,9-12,29H2,(H,34,36)/t16-,17-,18+,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50403725 (CHEMBL2112326) Show SMILES NCCNC(=O)c1c2N[C@H]3CCCC[C@@H]3Nc2c2C(=O)c3ccccc3-c3ncnc1c23 Show InChI InChI=1S/C24H24N6O2/c25-9-10-26-24(32)18-20-16-17(21-22(18)30-15-8-4-3-7-14(15)29-21)23(31)13-6-2-1-5-12(13)19(16)27-11-28-20/h1-2,5-6,11,14-15,29-30H,3-4,7-10,25H2,(H,26,32)/t14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to 5HT transporter by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50005127 (1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50075921 (8N-(2-aminoethyl)-15-oxo-(9aR,13aS)-11,12,13,15-te...) Show SMILES NCCNC(=O)c1c2N[C@@H]3CCCC[C@@H]3N=c2c2c(O)c3ccccc3c3ncnc1c23 |c:16| Show InChI InChI=1S/C24H24N6O2/c25-9-10-26-24(32)18-20-16-17(21-22(18)30-15-8-4-3-7-14(15)29-21)23(31)13-6-2-1-5-12(13)19(16)27-11-28-20/h1-2,5-6,11,14-15,30-31H,3-4,7-10,25H2,(H,26,32)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	367	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187384 (CHEMBL209072 | N-(3-{4-[4-(toluene-4-sulfonylamino...) Show SMILES CCC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H34N4O3S/c1-3-24(29)26-21-7-6-8-22(19-21)28-17-15-27(16-18-28)14-5-4-13-25-32(30,31)23-11-9-20(2)10-12-23/h6-12,19,25H,3-5,13-18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50187381 (CHEMBL209324 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H31N3O3S/c1-19-9-11-20(12-10-19)29(26,27)23-13-5-6-14-24-15-17-25(18-16-24)21-7-3-4-8-22(21)28-2/h3-4,7-12,23H,5-6,13-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 2 (Mus musculus)	BDBM50075924 (13-Oxo-10,11,12,13-tetrahydro-9H-5,7,9,12-tetraaza...) Show SMILES NCCNC(=O)c1c2NCCN=c2c2c(O)c3ccccc3c3ncnc1c23 |c:11| Show InChI InChI=1S/C20H18N6O2/c21-5-6-24-20(28)14-16-12-13(17-18(14)23-8-7-22-17)19(27)11-4-2-1-3-10(11)15(12)25-9-26-16/h1-4,9,23,27H,5-8,21H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A Subsidiary of Agouron Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 2 beta				Bioorg Med Chem Lett 9: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2TD9WJJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50187377 (CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to 5HT7 receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair

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