Found 114 hits with Last Name = 'dibrino' and Initial = 'jn' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50120502
(2-Amino-N-[(R)-2-(3a-benzyl-2-tert-butyl-3-oxo-2,3...)Show SMILES CC(C)(C)N1N=C2CCN(CC2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccc(F)c(F)c1)NC(=O)C(C)(C)N |t:5| Show InChI InChI=1S/C31H39F2N5O4/c1-29(2,3)38-28(41)31(16-20-9-7-6-8-10-20)19-37(14-13-25(31)36-38)26(39)24(35-27(40)30(4,5)34)18-42-17-21-11-12-22(32)23(33)15-21/h6-12,15,24H,13-14,16-19,34H2,1-5H3,(H,35,40)/t24-,31?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development
Curated by ChEMBL
| Assay Description
In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ... |
Bioorg Med Chem Lett 12: 3279-82 (2002)
BindingDB Entry DOI: 10.7270/Q23F4NZZ |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50120504
(2-Amino-N-[(R)-2-[3a-benzyl-3-oxo-2-(2,2,2-trifluo...)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccc(F)c(F)c1)C(=O)N1CCC2=NN(CC(F)(F)F)C(=O)C2(Cc2ccccc2)C1 |t:25| Show InChI InChI=1S/C29H32F5N5O4/c1-27(2,35)25(41)36-22(15-43-14-19-8-9-20(30)21(31)12-19)24(40)38-11-10-23-28(16-38,13-18-6-4-3-5-7-18)26(42)39(37-23)17-29(32,33)34/h3-9,12,22H,10-11,13-17,35H2,1-2H3,(H,36,41)/t22-,28?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| PubMed
| 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development
Curated by ChEMBL
| Assay Description
In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ... |
Bioorg Med Chem Lett 12: 3279-82 (2002)
BindingDB Entry DOI: 10.7270/Q23F4NZZ |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50120505
(2-Amino-N-{(R)-1-(2,4-difluoro-benzyloxymethyl)-2-...)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccc(F)cc1F)C(=O)N1CCC2=NN(CC(F)(F)F)C(=O)[C@]2(Cc2ccccn2)C1 |t:25| Show InChI InChI=1S/C28H31F5N6O4/c1-26(2,34)24(41)36-21(14-43-13-17-6-7-18(29)11-20(17)30)23(40)38-10-8-22-27(15-38,12-19-5-3-4-9-35-19)25(42)39(37-22)16-28(31,32)33/h3-7,9,11,21H,8,10,12-16,34H2,1-2H3,(H,36,41)/t21-,27-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
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| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development
Curated by ChEMBL
| Assay Description
In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ... |
Bioorg Med Chem Lett 12: 3279-82 (2002)
BindingDB Entry DOI: 10.7270/Q23F4NZZ |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50083974
(2-Amino-N-[(R)-2-((R)-3a-benzyl-2-methyl-3-oxo-2,3...)Show SMILES CN1N=C2CCN(C[C@@]2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |t:2| Show InChI InChI=1S/C28H35N5O4/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20/h4-13,22H,14-19,29H2,1-3H3,(H,30,35)/t22-,28-/m1/s1 | PDB
Reactome pathway
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PC cid
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| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development
Curated by ChEMBL
| Assay Description
In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ... |
Bioorg Med Chem Lett 12: 3279-82 (2002)
BindingDB Entry DOI: 10.7270/Q23F4NZZ |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50120503
(2-Amino-N-[(R)-2-(3a-benzyl-2-methyl-3-oxo-2,3,3a,...)Show SMILES CN1N=C2CCN(CC2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccc(F)c(F)c1)NC(=O)C(C)(C)N |t:2| Show InChI InChI=1S/C28H33F2N5O4/c1-27(2,31)25(37)32-22(16-39-15-19-9-10-20(29)21(30)13-19)24(36)35-12-11-23-28(17-35,26(38)34(3)33-23)14-18-7-5-4-6-8-18/h4-10,13,22H,11-12,14-17,31H2,1-3H3,(H,32,37)/t22-,28?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development
Curated by ChEMBL
| Assay Description
In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ... |
Bioorg Med Chem Lett 12: 3279-82 (2002)
BindingDB Entry DOI: 10.7270/Q23F4NZZ |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215854
(CHEMBL301829)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
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MCE
PC cid
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| PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215854
(CHEMBL301829)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
PC sid
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| PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215854
(CHEMBL301829)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
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| PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215738
(CHEMBL52675)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215740
(CHEMBL48906)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C29H23FO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215740
(CHEMBL48906)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C29H23FO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215738
(CHEMBL52675)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215855
(CHEMBL51467)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)cc(F)c1C(O)=O Show InChI InChI=1S/C23H18F2O4/c24-16-10-18(21(23(27)28)19(25)11-16)14-6-7-17-20(9-14)29-12-15(22(17)26)8-13-4-2-1-3-5-13/h1-7,9-11,15,22,26H,8,12H2,(H,27,28)/t15-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215738
(CHEMBL52675)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50037218
(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O Show InChI InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
MCE
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| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215853
(CHEMBL417364)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C30H23F3O4/c31-30(32,33)23-11-13-24(29(35)36)26(16-23)21-10-12-25-27(15-21)37-17-22(28(25)34)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,34H,14,17H2,(H,35,36)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215853
(CHEMBL417364)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C30H23F3O4/c31-30(32,33)23-11-13-24(29(35)36)26(16-23)21-10-12-25-27(15-21)37-17-22(28(25)34)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,34H,14,17H2,(H,35,36)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50037218
(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O Show InChI InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
MCE
PC cid
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| n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Compound was evaluated for its ability to inhibit [3H]LTB4 binding to LTB4 receptors on guinea pig spleen membranes |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215854
(CHEMBL301829)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1 | PDB
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| n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215737
(CHEMBL50425)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1 | PDB
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| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215737
(CHEMBL50425)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1 | PDB
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| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50037218
(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O Show InChI InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1 | PDB
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| n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215739
(CHEMBL52374)Show SMILES OCc1ccc(cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1)C(F)(F)F Show InChI InChI=1S/C24H21F3O3/c25-24(26,27)19-8-6-17(13-28)21(12-19)16-7-9-20-22(11-16)30-14-18(23(20)29)10-15-4-2-1-3-5-15/h1-9,11-12,18,23,28-29H,10,13-14H2/t18-,23+/m0/s1 | PDB
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| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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GoogleScholar
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| CHEMBL
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| PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215738
(CHEMBL52675)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215738
(CHEMBL52675)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
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| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215741
(CHEMBL418264)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C23H19ClO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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GoogleScholar
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| CHEMBL
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PC sid
UniChem
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215868
(CHEMBL51535)Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1 Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1 | PDB
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antibodypedia
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| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215859
(CHEMBL51775)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1-c1nn[nH]n1 Show InChI InChI=1S/C23H19FN4O2/c24-17-7-9-18(23-25-27-28-26-23)20(12-17)15-6-8-19-21(11-15)30-13-16(22(19)29)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,29H,10,13H2,(H,25,26,27,28)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
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UniChem
Patents
| PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215743
(CHEMBL51219)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1ccc(F)cc1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-17-7-9-18(20(12-17)23(26)27)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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GoogleScholar
AffyNet
| CHEMBL
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PC sid
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Similars
| PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215744
(CHEMBL299150)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(c1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)19-8-4-7-17(21(19)23(29)30)15-9-10-18-20(12-15)31-13-16(22(18)28)11-14-5-2-1-3-6-14/h1-10,12,16,22,28H,11,13H2,(H,29,30)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
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PC sid
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Similars
| PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215737
(CHEMBL50425)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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GoogleScholar
AffyNet
| CHEMBL
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PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215737
(CHEMBL50425)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C29H23ClO4/c30-23-11-13-24(29(32)33)26(16-23)21-10-12-25-27(15-21)34-17-22(28(25)31)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,31H,14,17H2,(H,32,33)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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GoogleScholar
AffyNet
| CHEMBL
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PC sid
UniChem
Similars
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| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215741
(CHEMBL418264)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C23H19ClO4/c24-17-7-9-18(23(26)27)20(12-17)15-6-8-19-21(11-15)28-13-16(22(19)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215742
(CHEMBL51492)Show SMILES O[C@@H]1[C@@H](CCc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C24H21FO4/c25-18-9-11-19(24(27)28)21(13-18)16-8-10-20-22(12-16)29-14-17(23(20)26)7-6-15-4-2-1-3-5-15/h1-5,8-13,17,23,26H,6-7,14H2,(H,27,28)/t17-,23+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
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| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215742
(CHEMBL51492)Show SMILES O[C@@H]1[C@@H](CCc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O Show InChI InChI=1S/C24H21FO4/c25-18-9-11-19(24(27)28)21(13-18)16-8-10-20-22(12-16)29-14-17(23(20)26)7-6-15-4-2-1-3-5-15/h1-5,8-13,17,23,26H,6-7,14H2,(H,27,28)/t17-,23+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
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UniChem
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| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215868
(CHEMBL51535)Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1 Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
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| CHEMBL
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| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215853
(CHEMBL417364)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C30H23F3O4/c31-30(32,33)23-11-13-24(29(35)36)26(16-23)21-10-12-25-27(15-21)37-17-22(28(25)34)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,34H,14,17H2,(H,35,36)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215853
(CHEMBL417364)Show SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F Show InChI InChI=1S/C30H23F3O4/c31-30(32,33)23-11-13-24(29(35)36)26(16-23)21-10-12-25-27(15-21)37-17-22(28(25)34)14-18-6-8-20(9-7-18)19-4-2-1-3-5-19/h1-13,15-16,22,28,34H,14,17H2,(H,35,36)/t22-,28+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215855
(CHEMBL51467)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)cc(F)c1C(O)=O Show InChI InChI=1S/C23H18F2O4/c24-16-10-18(21(23(27)28)19(25)11-16)14-6-7-17-20(9-14)29-12-15(22(17)26)8-13-4-2-1-3-5-13/h1-7,9-11,15,22,26H,8,12H2,(H,27,28)/t15-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215863
(CHEMBL52449)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/C23H19F4NO4S/c24-17-7-9-20(28-33(30,31)23(25,26)27)19(12-17)15-6-8-18-21(11-15)32-13-16(22(18)29)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28-29H,10,13H2/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215863
(CHEMBL52449)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/C23H19F4NO4S/c24-17-7-9-20(28-33(30,31)23(25,26)27)19(12-17)15-6-8-18-21(11-15)32-13-16(22(18)29)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28-29H,10,13H2/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215744
(CHEMBL299150)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(c1C(O)=O)C(F)(F)F Show InChI InChI=1S/C24H19F3O4/c25-24(26,27)19-8-4-7-17(21(19)23(29)30)15-9-10-18-20(12-15)31-13-16(22(18)28)11-14-5-2-1-3-6-14/h1-10,12,16,22,28H,11,13H2,(H,29,30)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215863
(CHEMBL52449)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/C23H19F4NO4S/c24-17-7-9-20(28-33(30,31)23(25,26)27)19(12-17)15-6-8-18-21(11-15)32-13-16(22(18)29)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28-29H,10,13H2/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215863
(CHEMBL52449)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/C23H19F4NO4S/c24-17-7-9-20(28-33(30,31)23(25,26)27)19(12-17)15-6-8-18-21(11-15)32-13-16(22(18)29)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28-29H,10,13H2/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
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