Compile Data Set for Download or QSAR

Found 480 hits with Last Name = 'dominguez' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494356 (CHEMBL3088070) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-5-1-13(2-6-17)14-4-8-19(22-26-28-29-27-22)21(11-14)32-18-7-3-15-12-25-20(23(30)31)10-16(15)9-18;/h1-2,4-6,8,11,15-16,18,20,25H,3,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494356 (CHEMBL3088070) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-5-1-13(2-6-17)14-4-8-19(22-26-28-29-27-22)21(11-14)32-18-7-3-15-12-25-20(23(30)31)10-16(15)9-18;/h1-2,4-6,8,11,15-16,18,20,25H,3,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494342 (CHEMBL3088072) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1cccs1 |r| Show InChI InChI=1S/C21H23N5O3S.ClH/c27-21(28)17-9-14-8-15(5-3-13(14)11-22-17)29-18-10-12(19-2-1-7-30-19)4-6-16(18)20-23-25-26-24-20;/h1-2,4,6-7,10,13-15,17,22H,3,5,8-9,11H2,(H,27,28)(H,23,24,25,26);1H/t13-,14+,15-,17-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494350 (CHEMBL3088064) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C23H25N5O3.ClH/c29-23(30)20-11-17-10-18(8-6-16(17)13-24-20)31-21-12-15(14-4-2-1-3-5-14)7-9-19(21)22-25-27-28-26-22;/h1-5,7,9,12,16-18,20,24H,6,8,10-11,13H2,(H,29,30)(H,25,26,27,28);1H/t16-,17+,18-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494365 (CHEMBL3085837) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(Cc2ccccc2)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C24H27N5O3.ClH/c30-24(31)21-13-18-12-19(8-7-17(18)14-25-21)32-22-11-16(10-15-4-2-1-3-5-15)6-9-20(22)23-26-28-29-27-23;/h1-6,9,11,17-19,21,25H,7-8,10,12-14H2,(H,30,31)(H,26,27,28,29);1H/t17-,18+,19-,21-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494355 (CHEMBL3085836) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(OCc2ccccc2)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C24H27N5O4.ClH/c30-24(31)21-11-17-10-19(7-6-16(17)13-25-21)33-22-12-18(32-14-15-4-2-1-3-5-15)8-9-20(22)23-26-28-29-27-23;/h1-5,8-9,12,16-17,19,21,25H,6-7,10-11,13-14H2,(H,30,31)(H,26,27,28,29);1H/t16-,17+,19-,21-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494364 (CHEMBL3088054) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cccc(Cl)c1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H20ClN5O3.ClH/c18-12-2-1-3-14(15(12)16-20-22-23-21-16)26-11-5-4-9-8-19-13(17(24)25)7-10(9)6-11;/h1-3,9-11,13,19H,4-8H2,(H,24,25)(H,20,21,22,23);1H/t9-,10+,11-,13-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494358 (CHEMBL3088058) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1cccc(Cl)c1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H21ClN6O2/c18-12-2-1-3-13(15(12)16-21-23-24-22-16)20-11-5-4-9-8-19-14(17(25)26)7-10(9)6-11/h1-3,9-11,14,19-20H,4-8H2,(H,25,26)(H,21,22,23,24)/t9-,10+,11-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly Curated by ChEMBL					Assay Description Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells				J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494351 (CHEMBL3088060) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1ccc(Cl)cc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H20ClN5O3.ClH/c18-11-2-4-15(13(7-11)16-20-22-23-21-16)26-12-3-1-9-8-19-14(17(24)25)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,24,25)(H,20,21,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494351 (CHEMBL3088060) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1ccc(Cl)cc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H20ClN5O3.ClH/c18-11-2-4-15(13(7-11)16-20-22-23-21-16)26-12-3-1-9-8-19-14(17(24)25)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,24,25)(H,20,21,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494055 (CHEMBL2440699) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1C(O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C23H25NO5.ClH/c25-22(26)19-9-7-15(14-4-2-1-3-5-14)12-21(19)29-18-8-6-16-13-24-20(23(27)28)11-17(16)10-18;/h1-5,7,9,12,16-18,20,24H,6,8,10-11,13H2,(H,25,26)(H,27,28);1H/t16-,17+,18-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 4				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494367 (CHEMBL3087685) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Sc1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H21N5O2S.ClH/c23-17(24)14-8-11-7-12(6-5-10(11)9-18-14)25-15-4-2-1-3-13(15)16-19-21-22-20-16;/h1-4,10-12,14,18H,5-9H2,(H,23,24)(H,19,20,21,22);1H/t10-,11+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494348 (CHEMBL3088069) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-3-1-2-13(8-17)14-5-7-19(22-26-28-29-27-22)21(11-14)32-18-6-4-15-12-25-20(23(30)31)10-16(15)9-18;/h1-3,5,7-8,11,15-16,18,20,25H,4,6,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494068 (CHEMBL2440688) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Sc1ccccc1C(O)=O |r| Show InChI InChI=1S/C17H21NO4S/c19-16(20)13-3-1-2-4-15(13)23-12-6-5-10-9-18-14(17(21)22)8-11(10)7-12/h1-4,10-12,14,18H,5-9H2,(H,19,20)(H,21,22)/t10-,11+,12-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50168964 ((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C17H22N6O2/c24-17(25)15-8-11-7-12(6-5-10(11)9-18-15)19-14-4-2-1-3-13(14)16-20-22-23-21-16/h1-4,10-12,15,18-19H,5-9H2,(H,24,25)(H,20,21,22,23)/t10-,11+,12-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494346 (CHEMBL3088074) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(OC(C)C)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C20H27N5O4.ClH/c1-11(2)28-15-5-6-16(19-22-24-25-23-19)18(9-15)29-14-4-3-12-10-21-17(20(26)27)8-13(12)7-14;/h5-6,9,11-14,17,21H,3-4,7-8,10H2,1-2H3,(H,26,27)(H,22,23,24,25);1H/t12-,13+,14-,17-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494347 (CHEMBL3088071) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1nccs1 |r| Show InChI InChI=1S/C20H22N6O3S.ClH/c27-20(28)16-8-13-7-14(3-1-12(13)10-22-16)29-17-9-11(19-21-5-6-30-19)2-4-15(17)18-23-25-26-24-18;/h2,4-6,9,12-14,16,22H,1,3,7-8,10H2,(H,27,28)(H,23,24,25,26);1H/t12-,13+,14-,16-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494352 (CHEMBL3088059) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1ccc(F)cc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H20FN5O3.ClH/c18-11-2-4-15(13(7-11)16-20-22-23-21-16)26-12-3-1-9-8-19-14(17(24)25)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,24,25)(H,20,21,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494061 (CHEMBL2440689) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1ccccc1C(O)=O |r| Show InChI InChI=1S/C17H22N2O4/c20-16(21)13-3-1-2-4-14(13)19-12-6-5-10-9-18-15(17(22)23)8-11(10)7-12/h1-4,10-12,15,18-19H,5-9H2,(H,20,21)(H,22,23)/t10-,11+,12-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor 3 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 3				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494366 (CHEMBL3088068) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccccc1Cl |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-19-4-2-1-3-17(19)13-6-8-18(22-26-28-29-27-22)21(11-13)32-16-7-5-14-12-25-20(23(30)31)10-15(14)9-16;/h1-4,6,8,11,14-16,20,25H,5,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t14-,15+,16-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494349 (CHEMBL3088066) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1cc(ccc1-c1nnn[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C23H26N6O2/c30-23(31)21-12-17-10-18(8-6-16(17)13-24-21)25-20-11-15(14-4-2-1-3-5-14)7-9-19(20)22-26-28-29-27-22/h1-5,7,9,11,16-18,21,24-25H,6,8,10,12-13H2,(H,30,31)(H,26,27,28,29)/t16-,17+,18-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494359 (CHEMBL3088055) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cccc(OC)c1-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H23N5O4.ClH/c1-26-14-3-2-4-15(16(14)17-20-22-23-21-17)27-12-6-5-10-9-19-13(18(24)25)8-11(10)7-12;/h2-4,10-13,19H,5-9H2,1H3,(H,24,25)(H,20,21,22,23);1H/t10-,11+,12-,13-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494361 (CHEMBL3088062) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(C)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H23N5O3.ClH/c1-10-2-5-14(17-20-22-23-21-17)16(6-10)26-13-4-3-11-9-19-15(18(24)25)8-12(11)7-13;/h2,5-6,11-13,15,19H,3-4,7-9H2,1H3,(H,24,25)(H,20,21,22,23);1H/t11-,12+,13-,15-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50168965 ((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C17H21N5O3/c23-17(24)14-8-11-7-12(6-5-10(11)9-18-14)25-15-4-2-1-3-13(15)16-19-21-22-20-16/h1-4,10-12,14,18H,5-9H2,(H,23,24)(H,19,20,21,22)/t10-,11+,12-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494051 (CHEMBL2440702) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Sc1cc(Cl)ccc1C(O)=O |r| Show InChI InChI=1S/C17H20ClNO4S.ClH/c18-11-2-4-13(16(20)21)15(7-11)24-12-3-1-9-8-19-14(17(22)23)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,20,21)(H,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494362 (CHEMBL3088063) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(OC)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H23N5O4.ClH/c1-26-12-4-5-14(17-20-22-23-21-17)16(8-12)27-13-3-2-10-9-19-15(18(24)25)7-11(10)6-13;/h4-5,8,10-11,13,15,19H,2-3,6-7,9H2,1H3,(H,24,25)(H,20,21,22,23);1H/t10-,11+,13-,15-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494059 (CHEMBL2440685) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1ccc(Cl)cc1C(O)=O |r| Show InChI InChI=1S/C17H20ClNO5.ClH/c18-11-2-4-15(13(7-11)16(20)21)24-12-3-1-9-8-19-14(17(22)23)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,20,21)(H,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50168964 ((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C17H22N6O2/c24-17(25)15-8-11-7-12(6-5-10(11)9-18-15)19-14-4-2-1-3-13(14)16-20-22-23-21-16/h1-4,10-12,15,18-19H,5-9H2,(H,24,25)(H,20,21,22,23)/t10-,11+,12-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly Curated by ChEMBL					Assay Description Inhibition of [3H]-KA binding to iontropic glutamate receptor 5				J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50168965 ((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C17H21N5O3/c23-17(24)14-8-11-7-12(6-5-10(11)9-18-14)25-15-4-2-1-3-13(15)16-19-21-22-20-16/h1-4,10-12,14,18H,5-9H2,(H,23,24)(H,19,20,21,22)/t10-,11+,12-,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly Curated by ChEMBL					Assay Description Inhibition of [3H]-KA binding to iontropic glutamate receptor 5				J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494360 (CHEMBL3085838) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(CCc2ccccc2)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C25H29N5O3.ClH/c31-25(32)22-14-19-13-20(10-9-18(19)15-26-22)33-23-12-17(7-6-16-4-2-1-3-5-16)8-11-21(23)24-27-29-30-28-24;/h1-5,8,11-12,18-20,22,26H,6-7,9-10,13-15H2,(H,31,32)(H,27,28,29,30);1H/t18-,19+,20-,22-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494348 (CHEMBL3088069) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-3-1-2-13(8-17)14-5-7-19(22-26-28-29-27-22)21(11-14)32-18-6-4-15-12-25-20(23(30)31)10-16(15)9-18;/h1-3,5,7-8,11,15-16,18,20,25H,4,6,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494362 (CHEMBL3088063) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(OC)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H23N5O4.ClH/c1-26-12-4-5-14(17-20-22-23-21-17)16(8-12)27-13-3-2-10-9-19-15(18(24)25)7-11(10)6-13;/h4-5,8,10-11,13,15,19H,2-3,6-7,9H2,1H3,(H,24,25)(H,20,21,22,23);1H/t10-,11+,13-,15-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494057 (CHEMBL2440703) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(Cl)ccc1C(O)=O |r| Show InChI InChI=1S/C17H20ClNO5.ClH/c18-11-2-4-13(16(20)21)15(7-11)24-12-3-1-9-8-19-14(17(22)23)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,20,21)(H,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494347 (CHEMBL3088071) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1nccs1 |r| Show InChI InChI=1S/C20H22N6O3S.ClH/c27-20(28)16-8-13-7-14(3-1-12(13)10-22-16)29-17-9-11(19-21-5-6-30-19)2-4-15(17)18-23-25-26-24-18;/h2,4-6,9,12-14,16,22H,1,3,7-8,10H2,(H,27,28)(H,23,24,25,26);1H/t12-,13+,14-,16-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86751 (CHEMBL14935 | LY 293558 | LY-293558) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](CCc3nnn[nH]3)CC[C@H]2CN1 Show InChI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly Curated by ChEMBL					Assay Description Inhibition of [3H]-AMPA binding to human Ionontropic glutamate receptor 2				J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494350 (CHEMBL3088064) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C23H25N5O3.ClH/c29-23(30)20-11-17-10-18(8-6-16(17)13-24-20)31-21-12-15(14-4-2-1-3-5-14)7-9-19(21)22-25-27-28-26-22;/h1-5,7,9,12,16-18,20,24H,6,8,10-11,13H2,(H,29,30)(H,25,26,27,28);1H/t16-,17+,18-,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494060 (CHEMBL2440687) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1ccccc1C(O)=O |r| Show InChI InChI=1S/C17H21NO5.ClH/c19-16(20)13-3-1-2-4-15(13)23-12-6-5-10-9-18-14(17(21)22)8-11(10)7-12;/h1-4,10-12,14,18H,5-9H2,(H,19,20)(H,21,22);1H/t10-,11+,12-,14-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluK1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494352 (CHEMBL3088059) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1ccc(F)cc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C17H20FN5O3.ClH/c18-11-2-4-15(13(7-11)16-20-22-23-21-16)26-12-3-1-9-8-19-14(17(24)25)6-10(9)5-12;/h2,4,7,9-10,12,14,19H,1,3,5-6,8H2,(H,24,25)(H,20,21,22,23);1H/t9-,10+,12-,14-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494340 (CHEMBL3088065) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1cc(C)ccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H24N6O2/c1-10-2-5-14(17-21-23-24-22-17)15(6-10)20-13-4-3-11-9-19-16(18(25)26)8-12(11)7-13/h2,5-6,11-13,16,19-20H,3-4,7-9H2,1H3,(H,25,26)(H,21,22,23,24)/t11-,12+,13-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494341 (LY-293,558 | LY-293558 | NGX-424 | TEZAMPANEL) Show SMILES [H][C@@]12CC[C@H](CCc3nn[nH]n3)C[C@]1([H])C[C@H](NC2)C(O)=O Show InChI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494344 (CHEMBL3087684) Show SMILES Cl.[H][C@@]12CC[C@H](Cc3ccccc3-c3nnn[nH]3)C[C@]1([H])C[C@H](NC2)C(O)=O |r| Show InChI InChI=1S/C18H23N5O2.ClH/c24-18(25)16-9-14-8-11(5-6-13(14)10-19-16)7-12-3-1-2-4-15(12)17-20-22-23-21-17;/h1-4,11,13-14,16,19H,5-10H2,(H,24,25)(H,20,21,22,23);1H/t11-,13+,14-,16+;/m1./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494354 (CHEMBL3088056) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1cccc(C)c1-c1nnn[nH]1 |r| Show InChI InChI=1S/C18H24N6O2/c1-10-3-2-4-14(16(10)17-21-23-24-22-17)20-13-6-5-11-9-19-15(18(25)26)8-12(11)7-13/h2-4,11-13,15,19-20H,5-9H2,1H3,(H,25,26)(H,21,22,23,24)/t11-,12+,13-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86751 (CHEMBL14935 | LY 293558 | LY-293558) Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](CCc3nnn[nH]3)CC[C@H]2CN1 Show InChI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494067 (CHEMBL2440517) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1ccc(Cl)cc1C(O)=O |r| Show InChI InChI=1S/C17H21ClN2O4/c18-11-2-4-14(13(7-11)16(21)22)20-12-3-1-9-8-19-15(17(23)24)6-10(9)5-12/h2,4,7,9-10,12,15,19-20H,1,3,5-6,8H2,(H,21,22)(H,23,24)/t9-,10+,12-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494349 (CHEMBL3088066) Show SMILES [H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Nc1cc(ccc1-c1nnn[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C23H26N6O2/c30-23(31)21-12-17-10-18(8-6-16(17)13-24-21)25-20-11-15(14-4-2-1-3-5-14)7-9-19(20)22-26-28-29-27-22/h1-5,7,9,11,16-18,21,24-25H,6,8,10,12-13H2,(H,30,31)(H,26,27,28,29)/t16-,17+,18-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair

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