Compile Data Set for Download or QSAR

Found 372 hits with Last Name = 'endo' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554205 (CHEMBL4757242) Show SMILES CCCCCN(C)Cc1cc(ccc1NC(=O)c1cc2cc(F)cc(NC)c2[nH]c1=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554208 (CHEMBL4784687) Show SMILES OC(=O)C(F)(F)F.CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3CNC3CCCCC3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554207 (CHEMBL4758336) Show SMILES Cl.CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3CN(CCO)C3CCCCC3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305129 (6-(2-aminoethoxy)-2-(4-phenoxyphenyl)-9,10-dihydro...) Show SMILES NCCOc1ccc2CCn3nc(c(C(N)=O)c3Nc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H25N5O3/c27-13-15-33-21-11-6-17-12-14-31-26(29-22(17)16-21)23(25(28)32)24(30-31)18-7-9-20(10-8-18)34-19-4-2-1-3-5-19/h1-11,16,29H,12-15,27H2,(H2,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554204 (CHEMBL4743844) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3CN3CCCCC3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554200 (CHEMBL4764566) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305140 (7-(2-aminoethoxy)-2-(4-phenoxyphenyl)-9,10-dihydro...) Show SMILES NCCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H25N5O3/c27-13-15-33-21-10-11-22-18(16-21)12-14-31-26(29-22)23(25(28)32)24(30-31)17-6-8-20(9-7-17)34-19-4-2-1-3-5-19/h1-11,16,29H,12-15,27H2,(H2,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554197 (CHEMBL4776319) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3)C(=O)NS(=O)(=O)N(C)C)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305119 (7-(2-(dimethylamino)ethoxy)-2-(4-hydroxyphenyl)-9,...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(O)cc1 Show InChI InChI=1S/C22H25N5O3/c1-26(2)11-12-30-17-7-8-18-15(13-17)9-10-27-22(24-18)19(21(23)29)20(25-27)14-3-5-16(28)6-4-14/h3-8,13,24,28H,9-12H2,1-2H3,(H2,23,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50549700 (CHEMBL4740126) Show SMILES OC(=O)c1cc(ncn1)-c1ccc(Cl)c(OC2CC2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of KMO (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127753 BindingDB Entry DOI: 10.7270/Q2XK8K55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305131 (6-(3-(dimethylamino)propoxy)-2-(4-phenoxyphenyl)-9...) Show SMILES CN(C)CCCOc1ccc2CCn3nc(c(C(N)=O)c3Nc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H31N5O3/c1-33(2)16-6-18-36-24-14-9-20-15-17-34-29(31-25(20)19-24)26(28(30)35)27(32-34)21-10-12-23(13-11-21)37-22-7-4-3-5-8-22/h3-5,7-14,19,31H,6,15-18H2,1-2H3,(H2,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554219 (CHEMBL4798551) Show SMILES OC=O.CNc1cc(F)cc2c(NCCCN)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554203 (CHEMBL4779288) Show SMILES Cl.CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3CN(C)C3CCCCC3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305139 (6-(2-(4-methylpiperazin-1-yl)ethoxy)-2-(4-phenoxyp...) Show SMILES CN1CCN(CCOc2ccc3CCn4nc(c(C(N)=O)c4Nc3c2)-c2ccc(Oc3ccccc3)cc2)CC1 Show InChI InChI=1S/C31H34N6O3/c1-35-15-17-36(18-16-35)19-20-39-26-12-7-22-13-14-37-31(33-27(22)21-26)28(30(32)38)29(34-37)23-8-10-25(11-9-23)40-24-5-3-2-4-6-24/h2-12,21,33H,13-20H2,1H3,(H2,32,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305117 (7-(2-morpholinoethoxy)-2-(4-phenoxyphenyl)-9,10-di...) Show SMILES NC(=O)c1c2Nc3ccc(OCCN4CCOCC4)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C30H31N5O4/c31-29(36)27-28(21-6-8-24(9-7-21)39-23-4-2-1-3-5-23)33-35-13-12-22-20-25(10-11-26(22)32-30(27)35)38-19-16-34-14-17-37-18-15-34/h1-11,20,32H,12-19H2,(H2,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554210 (CHEMBL4757030) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3CN(CC(O)=O)C3CCCCC3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50305126 (7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H29N5O3/c1-32(2)16-17-35-23-12-13-24-20(18-23)14-15-33-28(30-24)25(27(29)34)26(31-33)19-8-10-22(11-9-19)36-21-6-4-3-5-7-21/h3-13,18,30H,14-17H2,1-2H3,(H2,29,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554202 (CHEMBL4762067) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(cc3CN(C)C3CC3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554220 (CHEMBL4764515) Show SMILES OC=O.CNc1cc(F)cc2c(NCC3CNC3)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305126 (7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H29N5O3/c1-32(2)16-17-35-23-12-13-24-20(18-23)14-15-33-28(30-24)25(27(29)34)26(31-33)19-8-10-22(11-9-19)36-21-6-4-3-5-7-21/h3-13,18,30H,14-17H2,1-2H3,(H2,29,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305142 (7-(2-hydroxyethoxy)-2-(4-phenoxyphenyl)-9,10-dihyd...) Show SMILES NC(=O)c1c2Nc3ccc(OCCO)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H24N4O4/c27-25(32)23-24(17-6-8-20(9-7-17)34-19-4-2-1-3-5-19)29-30-13-12-18-16-21(33-15-14-31)10-11-22(18)28-26(23)30/h1-11,16,28,31H,12-15H2,(H2,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305138 (6-(2-morpholinoethoxy)-2-(4-phenoxyphenyl)-9,10-di...) Show SMILES NC(=O)c1c2Nc3cc(OCCN4CCOCC4)ccc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C30H31N5O4/c31-29(36)27-28(22-7-9-24(10-8-22)39-23-4-2-1-3-5-23)33-35-13-12-21-6-11-25(20-26(21)32-30(27)35)38-19-16-34-14-17-37-18-15-34/h1-11,20,32H,12-19H2,(H2,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554206 (CHEMBL4798088) Show SMILES CCCCCN(CCCCC)Cc1cc(ccc1NC(=O)c1cc2cc(F)cc(NC)c2[nH]c1=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305121 (7-(2-(dimethylamino)ethoxy)-2-(4-(phenylamino)phen...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Nc2ccccc2)cc1 Show InChI InChI=1S/C28H30N6O2/c1-33(2)16-17-36-23-12-13-24-20(18-23)14-15-34-28(31-24)25(27(29)35)26(32-34)19-8-10-22(11-9-19)30-21-6-4-3-5-7-21/h3-13,18,30-31H,14-17H2,1-2H3,(H2,29,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554217 (CHEMBL4776836) Show SMILES OC=O.CNc1cc(F)cc2c(NCCN)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305125 (2-(4-(3-(2,6-dichlorophenyl)ureido)phenyl)-7-(2-(d...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(NC(=O)Nc2c(Cl)cccc2Cl)cc1 Show InChI InChI=1S/C29H29Cl2N7O3/c1-37(2)14-15-41-20-10-11-23-18(16-20)12-13-38-28(34-23)24(27(32)39)25(36-38)17-6-8-19(9-7-17)33-29(40)35-26-21(30)4-3-5-22(26)31/h3-11,16,34H,12-15H2,1-2H3,(H2,32,39)(H2,33,35,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554199 (CHEMBL4763869) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3cnc(nc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305141 (7-(3-(dimethylamino)propoxy)-2-(4-phenoxyphenyl)-9...) Show SMILES CN(C)CCCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C29H31N5O3/c1-33(2)16-6-18-36-24-13-14-25-21(19-24)15-17-34-29(31-25)26(28(30)35)27(32-34)20-9-11-23(12-10-20)37-22-7-4-3-5-8-22/h3-5,7-14,19,31H,6,15-18H2,1-2H3,(H2,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305135 (2-(3-carbamoyl-2-(4-phenoxyphenyl)-9,10-dihydro-4H...) Show SMILES NC(=O)c1c2Nc3cc(OCC(O)=O)ccc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H22N4O5/c27-25(33)23-24(17-7-9-19(10-8-17)35-18-4-2-1-3-5-18)29-30-13-12-16-6-11-20(34-15-22(31)32)14-21(16)28-26(23)30/h1-11,14,28H,12-13,15H2,(H2,27,33)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305122 (2-(4-(2,6-dichlorobenzylamino)phenyl)-7-(2-(dimeth...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(NCc2c(Cl)cccc2Cl)cc1 Show InChI InChI=1S/C29H30Cl2N6O2/c1-36(2)14-15-39-21-10-11-25-19(16-21)12-13-37-29(34-25)26(28(32)38)27(35-37)18-6-8-20(9-7-18)33-17-22-23(30)4-3-5-24(22)31/h3-11,16,33-34H,12-15,17H2,1-2H3,(H2,32,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554225 (CHEMBL4744156) Show SMILES CNc1cc(F)cc2c(O)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305118 (7-(2-(4-methylpiperazin-1-yl)ethoxy)-2-(4-phenoxyp...) Show SMILES CN1CCN(CCOc2ccc3Nc4c(C(N)=O)c(nn4CCc3c2)-c2ccc(Oc3ccccc3)cc2)CC1 Show InChI InChI=1S/C31H34N6O3/c1-35-15-17-36(18-16-35)19-20-39-26-11-12-27-23(21-26)13-14-37-31(33-27)28(30(32)38)29(34-37)22-7-9-25(10-8-22)40-24-5-3-2-4-6-24/h2-12,21,33H,13-20H2,1H3,(H2,32,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305130 (6-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...) Show SMILES CN(C)CCOc1ccc2CCn3nc(c(C(N)=O)c3Nc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H29N5O3/c1-32(2)16-17-35-23-13-8-19-14-15-33-28(30-24(19)18-23)25(27(29)34)26(31-33)20-9-11-22(12-10-20)36-21-6-4-3-5-7-21/h3-13,18,30H,14-17H2,1-2H3,(H2,29,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305143 (7-(2-amino-2-oxoethoxy)-2-(4-phenoxyphenyl)-9,10-d...) Show SMILES NC(=O)COc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H23N5O4/c27-22(32)15-34-20-10-11-21-17(14-20)12-13-31-26(29-21)23(25(28)33)24(30-31)16-6-8-19(9-7-16)35-18-4-2-1-3-5-18/h1-11,14,29H,12-13,15H2,(H2,27,32)(H2,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554223 (CHEMBL4741723) Show SMILES OC=O.CNc1cc(F)cc2c(NCC3CCNCC3)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305132 (6-(2-hydroxyethoxy)-2-(4-phenoxyphenyl)-9,10-dihyd...) Show SMILES NC(=O)c1c2Nc3cc(OCCO)ccc3CCn2nc1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H24N4O4/c27-25(32)23-24(18-7-9-20(10-8-18)34-19-4-2-1-3-5-19)29-30-13-12-17-6-11-21(33-15-14-31)16-22(17)28-26(23)30/h1-11,16,28,31H,12-15H2,(H2,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305134 (6-(2-amino-2-oxoethoxy)-2-(4-phenoxyphenyl)-9,10-d...) Show SMILES NC(=O)COc1ccc2CCn3nc(c(C(N)=O)c3Nc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H23N5O4/c27-22(32)15-34-20-11-6-16-12-13-31-26(29-21(16)14-20)23(25(28)33)24(30-31)17-7-9-19(10-8-17)35-18-4-2-1-3-5-18/h1-11,14,29H,12-13,15H2,(H2,27,32)(H2,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554214 (CHEMBL4755340) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(CO)cc3CN(CCO)C3CCCCC3)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554229 (CHEMBL4776589) Show SMILES CNc1cccc2cc(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kynurenine 3-monooxygenase (Mus musculus)	BDBM50549707 (CHEMBL4781856) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(nn1)-c1ccccc1N1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127753 BindingDB Entry DOI: 10.7270/Q2XK8K55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase CSK (Homo sapiens (Human))	BDBM50305126 (7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H29N5O3/c1-32(2)16-17-35-23-12-13-24-20(18-23)14-15-33-28(30-24)25(27(29)34)26(31-33)19-8-10-22(11-9-19)36-21-6-4-3-5-7-21/h3-13,18,30H,14-17H2,1-2H3,(H2,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of Csk				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50549704 (CHEMBL4764931) Show SMILES CN(C)c1cccc(c1)S(=O)(=O)Nc1ccc(nn1)-c1ccccc1N1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127753 BindingDB Entry DOI: 10.7270/Q2XK8K55
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554213 (CHEMBL4755858) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(CO)cc3CN(C)C3CCCCC3)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Kynurenine 3-monooxygenase (Homo sapiens (Human))	BDBM50549705 (CHEMBL4756311) Show SMILES CN1CCc2cccc(c12)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)nn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127753 BindingDB Entry DOI: 10.7270/Q2XK8K55
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305123 (CHEMBL595625 | benzyl 4-(3-carbamoyl-7-(2-(dimethy...) Show SMILES CN(C)CCOc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C30H32N6O4/c1-35(2)16-17-39-24-12-13-25-22(18-24)14-15-36-29(33-25)26(28(31)37)27(34-36)21-8-10-23(11-9-21)32-30(38)40-19-20-6-4-3-5-7-20/h3-13,18,33H,14-17,19H2,1-2H3,(H2,31,37)(H,32,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554198 (CHEMBL4740347) Show SMILES CNc1cc(F)cc2cc(C(=O)Nc3ccc(C(O)=O)c(O)c3)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554218 (CHEMBL4779138) Show SMILES OC=O.CNCCNc1c(C(=O)Nc2ccc(cc2)C(O)=O)c(=O)[nH]c2c(NC)cc(F)cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Rattus norvegicus)	BDBM50590497 (CHEMBL5182987) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(=O)NCCOCCOCCOCCO)Cc1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50554222 (CHEMBL4792659) Show SMILES OC=O.CNc1cc(F)cc2c(NCC3(N)CCC3)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115776 BindingDB Entry DOI: 10.7270/Q2W66QFJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305128 (7-methoxy-2-(4-phenoxyphenyl)-9,10-dihydro-4H-benz...) Show SMILES COc1ccc2Nc3c(C(N)=O)c(nn3CCc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H22N4O3/c1-31-20-11-12-21-17(15-20)13-14-29-25(27-21)22(24(26)30)23(28-29)16-7-9-19(10-8-16)32-18-5-3-2-4-6-18/h2-12,15,27H,13-14H2,1H3,(H2,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LCK by scintillation counting				Bioorg Med Chem Lett 20: 112-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.013 BindingDB Entry DOI: 10.7270/Q22Z15NV
					More data for this Ligand-Target Pair

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