Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240938 (CHEMBL4071862) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240954 (CHEMBL4101576) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240970 (CHEMBL4092640) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240967 (CHEMBL4090181) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240955 (CHEMBL4083571) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240958 (CHEMBL4065350) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048691 (CHEMBL3315139) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50320463 (CHEMBL218994 | D[CFWKYC]V | H-Asp-Cys-Phe-Trp-Lys-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240947 (CHEMBL4086783) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240971 (CHEMBL4096973) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048696 (CHEMBL3315142) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467] (Homo sapiens (Human)) | BDBM25877 (CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee | Assay Description The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o... | Bioorg Med Chem 16: 8853-62 (2008) Article DOI: 10.1016/j.bmc.2008.08.072 BindingDB Entry DOI: 10.7270/Q2GX48WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM25877 (CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha3-beta3-gamma2 subunits expressed in L(tk-)cells | Bioorg Med Chem Lett 14: 1465-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.018 BindingDB Entry DOI: 10.7270/Q2W958M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240939 (CHEMBL4063231) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048695 (CHEMBL3315141) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.724 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048701 (CHEMBL3315148) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50413784 (UROTENSIN-II) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048700 (CHEMBL3315147) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048699 (CHEMBL3315146) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517327 (CHEMBL4472928) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048697 (CHEMBL3315144) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517320 (CHEMBL4568153) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048703 (CHEMBL3315150) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048705 (CHEMBL3315152) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240965 (CHEMBL4084291) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048692 (CHEMBL3315140) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240949 (CHEMBL4073963) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048702 (CHEMBL3315149) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517312 (CHEMBL4526244) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240941 (CHEMBL4078954) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517325 (CHEMBL4590360) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240950 (CHEMBL4094512) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240968 (CHEMBL4093848) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517316 (CHEMBL4462940) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517315 (CHEMBL4454498) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240966 (CHEMBL4069115) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240942 (CHEMBL4103205) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50320463 (CHEMBL218994 | D[CFWKYC]V | H-Asp-Cys-Phe-Trp-Lys-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50411333 (URANTIDE) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467] (Homo sapiens (Human)) | BDBM25877 (CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee | Assay Description The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o... | Bioorg Med Chem 16: 8853-62 (2008) Article DOI: 10.1016/j.bmc.2008.08.072 BindingDB Entry DOI: 10.7270/Q2GX48WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467] (Homo sapiens (Human)) | BDBM25880 (5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee | Assay Description The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o... | Bioorg Med Chem 16: 8853-62 (2008) Article DOI: 10.1016/j.bmc.2008.08.072 BindingDB Entry DOI: 10.7270/Q2GX48WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50445383 (CHEMBL3104471) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048690 (CHEMBL3315143) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467] (Homo sapiens (Human)) | BDBM25885 (3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 7.40 | -43.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Wisconsin-Milwaukee | Assay Description The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o... | Bioorg Med Chem 16: 8853-62 (2008) Article DOI: 10.1016/j.bmc.2008.08.072 BindingDB Entry DOI: 10.7270/Q2GX48WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50517314 (Urotensin-II) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples "Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti... | J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50240940 (CHEMBL4084881) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting method | J Med Chem 60: 7579-7590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00981 BindingDB Entry DOI: 10.7270/Q21C202C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048704 (CHEMBL3315151) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urotensin-2 receptor (Homo sapiens (Human)) | BDBM50048698 (CHEMBL3315145) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples"Federico II" Curated by ChEMBL | Assay Description Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting method | J Med Chem 57: 5965-74 (2014) Article DOI: 10.1021/jm500218x BindingDB Entry DOI: 10.7270/Q2MC91NB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467] (Homo sapiens (Human)) | BDBM25883 (ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 13.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee | Assay Description The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o... | Bioorg Med Chem 16: 8853-62 (2008) Article DOI: 10.1016/j.bmc.2008.08.072 BindingDB Entry DOI: 10.7270/Q2GX48WR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM25879 (3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Milwaukee Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha1-beta3-gamma2 subunits expressed in L(tk-)cells | Bioorg Med Chem Lett 14: 1465-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.018 BindingDB Entry DOI: 10.7270/Q2W958M2 | |||||||||||
More data for this Ligand-Target Pair |
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