Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50060964 ((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by PDSP Ki Database | J Pharmacol Exp Ther 300: 478-86 (2002) Article DOI: 10.1124/jpet.300.2.478 BindingDB Entry DOI: 10.7270/Q2HX1B77 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319536 ((R)-2-(4-methylpiperidin-1-yl)-6-(2-(2-methylpyrro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174619 (CHEMBL197747 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Homo sapiens (Human)) | BDBM50060964 ((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 0.0560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by PDSP Ki Database | J Pharmacol Exp Ther 300: 478-86 (2002) Article DOI: 10.1124/jpet.300.2.478 BindingDB Entry DOI: 10.7270/Q2HX1B77 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158590 (1-(3-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50074627 (4-[2-(5,5-Dimethyl-hex-1-ynyl)-cyclopropyl]-1H-imi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing rat histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50319536 ((R)-2-(4-methylpiperidin-1-yl)-6-(2-(2-methylpyrro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174627 (CHEMBL199245 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine receptor H3 (Dog) | BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by PDSP Ki Database | J Pharmacol Exp Ther 305: 887-96 (2003) Article DOI: 10.1124/jpet.102.047183 BindingDB Entry DOI: 10.7270/Q22J69FK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158588 ((3,5-Difluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158596 ((3-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319552 ((R)-6-methyl-5-(6-(2-(2-methylpyrrolidin-1-yl)ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319549 ((R)-5-methyl-4-(6-(2-(2-methylpyrrolidin-1-yl)ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319509 ((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyridi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319517 ((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyrazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174621 (CHEMBL196467 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50174619 (CHEMBL197747 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for rat histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hrh3 protein (RAT) | BDBM50074629 (4-[(1R,2R)-2-(5,5-Dimethyl-hex-1-ynyl)-cyclopropyl...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by PDSP Ki Database | J Pharmacol Exp Ther 313: 165-75 (2005) Article DOI: 10.1124/jpet.104.078303 BindingDB Entry DOI: 10.7270/Q2SN07JC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319538 ((R)-1-(4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50200642 ((S)-4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphtha...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells | Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319554 ((R)-2-(2-methylimidazo[1,2-a]pyridin-3-yl)-6-(2-(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174613 (4-({2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174637 (CHEMBL196294 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319512 ((R)-2-(6-methylpyridin-3-yl)-6-(2-(2-methylpyrroli...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319547 ((R)-3-(4-chlorophenyl)-5-methyl-4-(6-(2-(2-methylp...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319528 ((R)-2-(1,5-dimethyl-1H-pyrazol-4-yl)-6-(2-(2-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50099325 (3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro functional activity at Alpha-1B adrenergic receptor in rat spleen | Bioorg Med Chem Lett 11: 1119-21 (2001) BindingDB Entry DOI: 10.7270/Q20V8DBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50200641 (4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)naphthalen-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells | Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hrh3 protein (RAT) | BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by PDSP Ki Database | J Pharmacol Exp Ther 305: 887-96 (2003) Article DOI: 10.1124/jpet.102.047183 BindingDB Entry DOI: 10.7270/Q22J69FK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (CALF) | BDBM50099320 (3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 0.181 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards bovine Alpha-1A adrenergic receptor | Bioorg Med Chem Lett 11: 1119-21 (2001) BindingDB Entry DOI: 10.7270/Q20V8DBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158609 ((4-Chloro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158607 ((3-Chloro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319566 ((R)-N,N-dimethyl-6-(5-methyl-4-(6-(2-(2-methylpyrr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50224191 ((R)-2-(1-(6-ethoxypyridazin-3-yl)-5-methyl-1H-pyra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174615 (CHEMBL424842 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319533 ((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyrimi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50224191 ((R)-2-(1-(6-ethoxypyridazin-3-yl)-5-methyl-1H-pyra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha methyl histamine from human H3 receptor expressed in C6 cells | J Med Chem 50: 5439-48 (2007) Article DOI: 10.1021/jm0705051 BindingDB Entry DOI: 10.7270/Q25M65G0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319508 ((R)-2,4-dimethyl-5-(6-(2-(2-methylpyrrolidin-1-yl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50222968 (Cipralisant | GT-2331) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 0.195 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards rat cortical H3 receptor | Bioorg Med Chem Lett 13: 1325-8 (2003) BindingDB Entry DOI: 10.7270/Q2HM59NM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319527 ((R)-2-(3-methyl-1H-pyrazol-4-yl)-6-(2-(2-methylpyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158599 (CHEMBL369502 | Cyclopropyl-(3-{2-[2-((R)-2-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158592 (CHEMBL368699 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM27210 ((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.210 | -55.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories | Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... | J Med Chem 51: 5423-30 (2008) Article DOI: 10.1021/jm8003625 BindingDB Entry DOI: 10.7270/Q21G0JK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158603 ((4-Fluoro-3-methyl-phenyl)-{2-[2-((R)-2-methyl-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM27210 ((2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cells | J Med Chem 52: 4640-9 (2009) Article DOI: 10.1021/jm900480x BindingDB Entry DOI: 10.7270/Q2Z31ZNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50099322 (3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.213 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards rat Alpha-1D adrenergic receptor | Bioorg Med Chem Lett 11: 1119-21 (2001) BindingDB Entry DOI: 10.7270/Q20V8DBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158605 (CHEMBL362662 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing human histamine H3 receptor | J Med Chem 48: 38-55 (2005) Article DOI: 10.1021/jm040118g BindingDB Entry DOI: 10.7270/Q2571CST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50319510 ((R)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)-2-(pyridi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor | Bioorg Med Chem Lett 20: 3295-300 (2010) Article DOI: 10.1016/j.bmcl.2010.04.045 BindingDB Entry DOI: 10.7270/Q2XW4JZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50200646 (4'-[3-((R)-2-methyl-pyrrolidin-1-yl)-propoxy]-biph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cells | Bioorg Med Chem Lett 17: 1443-6 (2007) Article DOI: 10.1016/j.bmcl.2006.11.073 BindingDB Entry DOI: 10.7270/Q2416WR3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50174620 (CHEMBL371258 | {2-[2-((R)-2-Methyl-pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human histamine H3 receptor using [3H]-N-alpha-methylhistamine | J Med Chem 48: 6482-90 (2005) Article DOI: 10.1021/jm0504398 BindingDB Entry DOI: 10.7270/Q25D8RDT | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 2228 total ) | Next | Last >> |