Found 44 hits with Last Name = 'feinstein' and Initial = 'rd' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50034128
(CHEMBL441396 | Neuropeptide Y(NPY) | Tyr-Pro-Ser-L...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C190H286N54O58/c1-16-94(9)149(179(294)233-128(81-141(194)254)168(283)225-123(74-93(7)8)171(286)239-150(95(10)17-2)180(295)240-151(100(15)247)181(296)221-116(32-23-67-208-190(202)203)155(270)220-118(57-60-140(193)253)160(275)218-115(31-22-66-207-189(200)201)158(273)235-133(186(301)302)79-105-45-55-111(252)56-46-105)238-172(287)126(78-104-43-53-110(251)54-44-104)228-167(282)127(80-106-86-204-90-210-106)229-157(272)114(30-21-65-206-188(198)199)219-164(279)122(73-92(5)6)223-154(269)97(12)212-173(288)134(88-245)236-166(281)125(77-103-41-51-109(250)52-42-103)227-165(280)124(76-102-39-49-108(249)50-40-102)226-156(271)113(29-20-64-205-187(196)197)216-152(267)96(11)211-162(277)121(72-91(3)4)224-169(284)130(84-147(263)264)231-161(276)119(59-62-145(259)260)217-153(268)98(13)213-176(291)137-34-25-68-241(137)182(297)99(14)214-163(278)129(83-146(261)262)230-159(274)117(58-61-144(257)258)215-143(256)87-209-175(290)136-33-24-70-243(136)185(300)132(82-142(195)255)234-170(285)131(85-148(265)266)232-177(292)139-36-27-71-244(139)184(299)120(28-18-19-63-191)222-174(289)135(89-246)237-178(293)138-35-26-69-242(138)183(298)112(192)75-101-37-47-107(248)48-38-101/h37-56,86,90-100,112-139,149-151,245-252H,16-36,57-85,87-89,191-192H2,1-15H3,(H2,193,253)(H2,194,254)(H2,195,255)(H,204,210)(H,209,290)(H,211,277)(H,212,288)(H,213,291)(H,214,278)(H,215,256)(H,216,267)(H,217,268)(H,218,275)(H,219,279)(H,220,270)(H,221,296)(H,222,289)(H,223,269)(H,224,284)(H,225,283)(H,226,271)(H,227,280)(H,228,282)(H,229,272)(H,230,274)(H,231,276)(H,232,292)(H,233,294)(H,234,285)(H,235,273)(H,236,281)(H,237,293)(H,238,287)(H,239,286)(H,240,295)(H,257,258)(H,259,260)(H,261,262)(H,263,264)(H,265,266)(H,301,302)(H4,196,197,205)(H4,198,199,206)(H4,200,201,207)(H4,202,203,208)/t94-,95-,96-,97-,98-,99-,100+,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,149-,150-,151-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046551
(CHEMBL2370625 | Tyr-c(Glu-Ser-Lys-Pro-Gly-Arg-His-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:95.97,63.65,23.148,79.81,133.135,34.35,113.115,96.100,55.57,88.91,1.0,wD:29.62,87.89,71.73,102.104,122.124,148.152,17.18,8.9,44.46,64.67,(-6.45,-17.84,;-5.3,-16.37,;-6.84,-16.6,;-7.58,-15.24,;-6.5,-14.15,;-5.1,-14.84,;-4.54,-13.41,;-5.91,-12.67,;-3.66,-12.16,;-4.82,-11.12,;-6.3,-11.6,;-7.46,-10.55,;-8.92,-11.03,;-10.11,-10,;-2.52,-11.15,;-1.16,-10.43,;-1.73,-8.99,;.35,-10.04,;.11,-8.5,;-1.34,-7.93,;1.9,-10,;3.42,-10.32,;3.89,-8.86,;4.83,-11,;6.05,-11.94,;7.03,-13.16,;7.7,-14.58,;9.16,-14.1,;8.02,-16.08,;7.99,-17.62,;7.6,-19.1,;6.88,-20.46,;5.85,-21.59,;6.89,-22.77,;4.58,-22.47,;5.32,-23.84,;6.89,-23.89,;7.82,-22.67,;9.29,-23.21,;9.26,-24.76,;7.77,-25.17,;3.15,-23.02,;1.62,-23.24,;1.68,-24.78,;.07,-23.1,;-.23,-24.6,;.94,-25.64,;.63,-27.14,;1.8,-28.17,;1.51,-29.69,;.04,-30.15,;2.67,-30.72,;-1.41,-22.6,;-2.75,-21.79,;-3.68,-22.99,;-3.85,-20.68,;-5.05,-21.63,;-4.68,-19.36,;-5.16,-17.9,;-6.68,-18.19,;9.53,-17.85,;10.2,-16.52,;10.71,-18.99,;12.08,-18.47,;12.34,-16.93,;13.73,-16.4,;11.23,-15.92,;11.49,-14.4,;13.19,-19.46,;12.94,-20.98,;14.58,-18.93,;15.69,-19.93,;15.43,-21.46,;16.54,-22.45,;17.91,-21.91,;16.28,-23.99,;17.06,-19.39,;17.33,-17.85,;18.18,-20.38,;19.56,-19.86,;19.81,-18.33,;21.18,-17.81,;21.46,-16.25,;22.28,-18.78,;20.66,-20.84,;20.4,-22.39,;22.05,-20.31,;23.16,-21.32,;22.88,-22.84,;24.01,-23.85,;21.52,-23.39,;21.25,-24.9,;24.53,-20.78,;24.8,-19.24,;25.64,-21.77,;27.03,-21.23,;27.28,-19.7,;26.18,-18.7,;28.65,-19.19,;28.14,-22.23,;27.87,-23.76,;29.5,-21.71,;30.63,-22.7,;30.35,-24.24,;31.46,-25.23,;31.21,-26.77,;32.31,-27.77,;32.06,-29.29,;33.17,-30.3,;30.68,-29.83,;32,-22.17,;32.26,-20.64,;33.11,-23.16,;34.49,-22.63,;34.76,-21.09,;36.12,-20.57,;36.4,-19.04,;35.29,-18.02,;37.77,-18.51,;35.61,-23.62,;35.34,-25.15,;36.97,-23.1,;38.08,-24.1,;37.83,-25.63,;38.92,-26.65,;38.68,-28.16,;39.79,-29.16,;39.53,-30.68,;40.64,-31.69,;38.16,-31.22,;39.46,-23.56,;39.73,-22.03,;40.58,-24.56,;41.96,-24.02,;42.23,-22.48,;43.59,-21.96,;44.72,-22.96,;46.09,-22.43,;46.35,-20.89,;47.74,-20.35,;45.24,-19.9,;43.85,-20.44,;43.08,-25.01,;44.45,-24.49,;42.8,-26.55,;5.64,-9.67,;7.19,-9.75,;7.94,-11.09,;7.99,-8.44,;9.55,-8.5,;7.24,-7.07,;7.31,-5.55,;8.11,-4.24,;7.37,-2.88,;5.81,-2.82,;5.27,-1.42,;4.98,-4.13,;5.75,-5.49,)| Show InChI InChI=1S/C98H157N33O26/c1-9-49(5)75(91(152)125-67(43-73(102)137)86(147)123-65(39-48(3)4)87(148)128-76(50(6)10-2)92(153)130-77(52(8)133)93(154)121-61(20-15-37-112-98(107)108)81(142)120-62(30-32-72(101)136)84(145)119-60(19-14-36-111-97(105)106)83(144)126-68(95(156)157)41-54-24-28-57(135)29-25-54)129-88(149)69-45-113-80(141)66(42-55-44-109-47-114-55)124-82(143)59(18-13-35-110-96(103)104)117-78(139)51(7)115-90(151)71-21-16-38-131(71)94(155)64(17-11-12-34-99)122-89(150)70(46-132)127-85(146)63(31-33-74(138)116-69)118-79(140)58(100)40-53-22-26-56(134)27-23-53/h22-29,44,47-52,58-71,75-77,132-135H,9-21,30-43,45-46,99-100H2,1-8H3,(H2,101,136)(H2,102,137)(H,109,114)(H,113,141)(H,115,151)(H,116,138)(H,117,139)(H,118,140)(H,119,145)(H,120,142)(H,121,154)(H,122,150)(H,123,147)(H,124,143)(H,125,152)(H,126,144)(H,127,146)(H,128,148)(H,129,149)(H,130,153)(H,156,157)(H4,103,104,110)(H4,105,106,111)(H4,107,108,112)/t49-,50-,51+,52+,58-,59-,60-,61-,62-,63-,64-,65-,66+,67-,68-,69-,70-,71-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046552
(CHEMBL2370635 | Tyr-c(Glu-Ser-Lys-Pro-(D-Ala)-Arg-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@]([H])(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)CC)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:29.62,90.93,34.35,105.108,125.128,82.85,151.156,17.18,8.9,44.46,wD:73.105,23.152,136.139,63.65,116.119,55.57,98.102,77.80,1.0,(-1.39,-13.1,;-.48,-14.73,;-1.94,-14.26,;-2.86,-15.49,;-1.94,-16.74,;-.48,-16.27,;-.12,-17.75,;-1.57,-18.28,;.57,-19.12,;-.71,-19.97,;-2.1,-19.28,;-3.39,-20.11,;-4.77,-19.44,;-6.06,-20.27,;1.56,-20.31,;2.81,-21.22,;2.02,-22.54,;4.22,-21.83,;3.77,-23.3,;2.28,-23.64,;5.74,-22.09,;7.27,-21.99,;7.56,-23.51,;8.76,-21.56,;10.11,-20.79,;11.23,-19.75,;12.08,-18.46,;13.44,-19.15,;12.61,-17.01,;12.78,-15.49,;12.61,-13.97,;12.08,-12.52,;11.23,-11.23,;12.41,-10.26,;10.11,-10.2,;11.03,-8.95,;12.55,-9.14,;13.31,-10.47,;14.83,-10.18,;15.02,-8.66,;13.61,-8.02,;8.76,-9.44,;7.27,-8.99,;7.56,-7.47,;5.74,-8.91,;5.65,-7.37,;6.94,-6.51,;6.86,-4.99,;8.15,-4.16,;8.06,-2.62,;9.35,-1.78,;6.68,-1.93,;4.22,-9.17,;2.81,-9.78,;2.02,-8.45,;1.56,-10.69,;.51,-9.57,;.57,-11.86,;-.12,-13.23,;-1.57,-12.72,;14.32,-15.49,;15.09,-16.81,;15.09,-14.17,;16.64,-14.17,;16.88,-15.69,;17.53,-17.06,;18.59,-18.18,;19.93,-18.95,;21.43,-19.31,;22.98,-19.19,;23.31,-20.67,;24.42,-18.62,;25.62,-17.67,;26.48,-16.4,;26.94,-14.93,;26.94,-13.4,;28.48,-13.18,;26.48,-11.92,;26.97,-10.12,;25.62,-10.67,;24.42,-9.71,;25.19,-8.38,;22.98,-9.15,;23.31,-7.66,;24.62,-6.58,;25.52,-7,;25.15,-5.71,;21.43,-9.04,;19.93,-9.38,;19.37,-7.95,;18.59,-10.14,;17.63,-8.94,;17.6,-7.49,;18.92,-6.74,;16.38,-6.74,;17.53,-11.26,;16.88,-12.65,;15.39,-12.19,;27.89,-11.26,;29.15,-12.12,;28,-9.74,;29.38,-9.08,;27.89,-17.06,;29.15,-16.2,;28,-18.59,;29.38,-19.25,;30.67,-18.39,;32.06,-19.05,;33.34,-18.19,;34.73,-18.86,;36,-18,;37.4,-18.66,;35.88,-16.47,;29.51,-20.79,;28.23,-21.66,;30.9,-21.46,;31.02,-22.98,;29.75,-23.84,;29.84,-25.38,;28.58,-26.25,;27.17,-25.58,;28.69,-27.77,;32.41,-23.64,;33.67,-22.78,;32.52,-25.18,;33.9,-25.84,;35.19,-24.98,;36.58,-25.65,;37.86,-24.78,;39.25,-25.46,;40.53,-24.59,;41.92,-25.25,;40.41,-23.05,;34.04,-27.37,;32.75,-28.23,;35.42,-28.03,;35.54,-29.57,;34.26,-30.44,;34.37,-31.96,;33.1,-32.81,;33.21,-34.35,;34.6,-35.03,;34.73,-36.54,;35.88,-34.16,;35.77,-32.62,;36.93,-30.24,;37.04,-31.76,;38.19,-29.37,;9.37,-22.97,;10.9,-23.15,;11.83,-21.92,;11.53,-24.55,;13.05,-24.73,;10.6,-25.79,;10.34,-27.14,;9.05,-26.37,;7.67,-27.07,;7.6,-28.56,;6.25,-29.24,;8.91,-29.31,;10.27,-28.61,)| Show InChI InChI=1S/C99H156N34O26/c1-6-51(4)78-94(156)125-65(87(149)121-61(18-12-38-113-98(106)107)82(144)124-63(29-32-74(102)137)86(148)122-62(19-13-39-114-99(108)109)85(147)130-70(96(158)159)43-54-23-27-57(136)28-24-54)30-33-76(139)111-36-10-8-15-59(83(145)129-69(45-75(103)138)89(151)127-67(41-50(2)3)90(152)132-78)123-91(153)71-47-115-81(143)68(44-55-46-110-49-116-55)128-84(146)60(17-11-37-112-97(104)105)119-79(141)52(5)117-93(155)73-20-14-40-133(73)95(157)66(16-7-9-35-100)126-92(154)72(48-134)131-88(150)64(31-34-77(140)118-71)120-80(142)58(101)42-53-21-25-56(135)26-22-53/h21-28,46,49-52,58-73,78,134-136H,6-20,29-45,47-48,100-101H2,1-5H3,(H2,102,137)(H2,103,138)(H,110,116)(H,111,139)(H,115,143)(H,117,155)(H,118,140)(H,119,141)(H,120,142)(H,121,149)(H,122,148)(H,123,153)(H,124,144)(H,125,156)(H,126,154)(H,127,151)(H,128,146)(H,129,145)(H,130,147)(H,131,150)(H,132,152)(H,158,159)(H4,104,105,112)(H4,106,107,113)(H4,108,109,114)/t51-,52+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,78-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046551
(CHEMBL2370625 | Tyr-c(Glu-Ser-Lys-Pro-Gly-Arg-His-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:95.97,63.65,23.148,79.81,133.135,34.35,113.115,96.100,55.57,88.91,1.0,wD:29.62,87.89,71.73,102.104,122.124,148.152,17.18,8.9,44.46,64.67,(-6.45,-17.84,;-5.3,-16.37,;-6.84,-16.6,;-7.58,-15.24,;-6.5,-14.15,;-5.1,-14.84,;-4.54,-13.41,;-5.91,-12.67,;-3.66,-12.16,;-4.82,-11.12,;-6.3,-11.6,;-7.46,-10.55,;-8.92,-11.03,;-10.11,-10,;-2.52,-11.15,;-1.16,-10.43,;-1.73,-8.99,;.35,-10.04,;.11,-8.5,;-1.34,-7.93,;1.9,-10,;3.42,-10.32,;3.89,-8.86,;4.83,-11,;6.05,-11.94,;7.03,-13.16,;7.7,-14.58,;9.16,-14.1,;8.02,-16.08,;7.99,-17.62,;7.6,-19.1,;6.88,-20.46,;5.85,-21.59,;6.89,-22.77,;4.58,-22.47,;5.32,-23.84,;6.89,-23.89,;7.82,-22.67,;9.29,-23.21,;9.26,-24.76,;7.77,-25.17,;3.15,-23.02,;1.62,-23.24,;1.68,-24.78,;.07,-23.1,;-.23,-24.6,;.94,-25.64,;.63,-27.14,;1.8,-28.17,;1.51,-29.69,;.04,-30.15,;2.67,-30.72,;-1.41,-22.6,;-2.75,-21.79,;-3.68,-22.99,;-3.85,-20.68,;-5.05,-21.63,;-4.68,-19.36,;-5.16,-17.9,;-6.68,-18.19,;9.53,-17.85,;10.2,-16.52,;10.71,-18.99,;12.08,-18.47,;12.34,-16.93,;13.73,-16.4,;11.23,-15.92,;11.49,-14.4,;13.19,-19.46,;12.94,-20.98,;14.58,-18.93,;15.69,-19.93,;15.43,-21.46,;16.54,-22.45,;17.91,-21.91,;16.28,-23.99,;17.06,-19.39,;17.33,-17.85,;18.18,-20.38,;19.56,-19.86,;19.81,-18.33,;21.18,-17.81,;21.46,-16.25,;22.28,-18.78,;20.66,-20.84,;20.4,-22.39,;22.05,-20.31,;23.16,-21.32,;22.88,-22.84,;24.01,-23.85,;21.52,-23.39,;21.25,-24.9,;24.53,-20.78,;24.8,-19.24,;25.64,-21.77,;27.03,-21.23,;27.28,-19.7,;26.18,-18.7,;28.65,-19.19,;28.14,-22.23,;27.87,-23.76,;29.5,-21.71,;30.63,-22.7,;30.35,-24.24,;31.46,-25.23,;31.21,-26.77,;32.31,-27.77,;32.06,-29.29,;33.17,-30.3,;30.68,-29.83,;32,-22.17,;32.26,-20.64,;33.11,-23.16,;34.49,-22.63,;34.76,-21.09,;36.12,-20.57,;36.4,-19.04,;35.29,-18.02,;37.77,-18.51,;35.61,-23.62,;35.34,-25.15,;36.97,-23.1,;38.08,-24.1,;37.83,-25.63,;38.92,-26.65,;38.68,-28.16,;39.79,-29.16,;39.53,-30.68,;40.64,-31.69,;38.16,-31.22,;39.46,-23.56,;39.73,-22.03,;40.58,-24.56,;41.96,-24.02,;42.23,-22.48,;43.59,-21.96,;44.72,-22.96,;46.09,-22.43,;46.35,-20.89,;47.74,-20.35,;45.24,-19.9,;43.85,-20.44,;43.08,-25.01,;44.45,-24.49,;42.8,-26.55,;5.64,-9.67,;7.19,-9.75,;7.94,-11.09,;7.99,-8.44,;9.55,-8.5,;7.24,-7.07,;7.31,-5.55,;8.11,-4.24,;7.37,-2.88,;5.81,-2.82,;5.27,-1.42,;4.98,-4.13,;5.75,-5.49,)| Show InChI InChI=1S/C98H157N33O26/c1-9-49(5)75(91(152)125-67(43-73(102)137)86(147)123-65(39-48(3)4)87(148)128-76(50(6)10-2)92(153)130-77(52(8)133)93(154)121-61(20-15-37-112-98(107)108)81(142)120-62(30-32-72(101)136)84(145)119-60(19-14-36-111-97(105)106)83(144)126-68(95(156)157)41-54-24-28-57(135)29-25-54)129-88(149)69-45-113-80(141)66(42-55-44-109-47-114-55)124-82(143)59(18-13-35-110-96(103)104)117-78(139)51(7)115-90(151)71-21-16-38-131(71)94(155)64(17-11-12-34-99)122-89(150)70(46-132)127-85(146)63(31-33-74(138)116-69)118-79(140)58(100)40-53-22-26-56(134)27-23-53/h22-29,44,47-52,58-71,75-77,132-135H,9-21,30-43,45-46,99-100H2,1-8H3,(H2,101,136)(H2,102,137)(H,109,114)(H,113,141)(H,115,151)(H,116,138)(H,117,139)(H,118,140)(H,119,145)(H,120,142)(H,121,154)(H,122,150)(H,123,147)(H,124,143)(H,125,152)(H,126,144)(H,127,146)(H,128,148)(H,129,149)(H,130,153)(H,156,157)(H4,103,104,110)(H4,105,106,111)(H4,107,108,112)/t49-,50-,51+,52+,58-,59-,60-,61-,62-,63-,64-,65-,66+,67-,68-,69-,70-,71-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046549
(CHEMBL410007 | Tyr-Pro-Ser-Lys-c(Glu-Asp-Asn-Pro-(...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N2CCC[C@@H]2C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@H](C)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C153H230N46O42/c1-10-77(5)120(144(235)190-107(69-116(157)209)136(227)184-102(62-76(3)4)138(229)196-121(78(6)11-2)145(236)197-122(81(9)202)146(237)183-99(27-19-59-172-153(165)166)127(218)181-100(50-52-115(156)208)131(222)179-98(26-18-58-171-152(163)164)130(221)192-110(149(240)241)67-86-38-48-92(207)49-39-86)195-139(230)105(66-85-36-46-91(206)47-37-85)187-135(226)106(68-87-72-167-75-173-87)188-129(220)97(25-17-57-170-151(161)162)178-125(216)94-23-13-15-55-168-118(211)53-51-101(182-126(217)95(22-12-14-54-154)180-141(232)112(74-201)194-143(234)114-29-20-60-198(114)147(238)93(155)63-82-30-40-88(203)41-31-82)132(223)189-108(71-119(212)213)137(228)191-109(70-117(158)210)148(239)199-61-21-28-113(199)142(233)175-80(8)124(215)177-96(24-16-56-169-150(159)160)128(219)185-103(64-83-32-42-89(204)43-33-83)133(224)186-104(65-84-34-44-90(205)45-35-84)134(225)193-111(73-200)140(231)174-79(7)123(214)176-94/h30-49,72,75-81,93-114,120-122,200-207H,10-29,50-71,73-74,154-155H2,1-9H3,(H2,156,208)(H2,157,209)(H2,158,210)(H,167,173)(H,168,211)(H,174,231)(H,175,233)(H,176,214)(H,177,215)(H,178,216)(H,179,222)(H,180,232)(H,181,218)(H,182,217)(H,183,237)(H,184,227)(H,185,219)(H,186,224)(H,187,226)(H,188,220)(H,189,223)(H,190,235)(H,191,228)(H,192,221)(H,193,225)(H,194,234)(H,195,230)(H,196,229)(H,197,236)(H,212,213)(H,240,241)(H4,159,160,169)(H4,161,162,170)(H4,163,164,171)(H4,165,166,172)/t77-,78-,79+,80+,81+,93-,94-,95-,96+,97-,98-,99-,100-,101+,102-,103-,104+,105-,106-,107-,108+,109-,110-,111-,112+,113+,114+,120-,121-,122-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046559
(CHEMBL427974 | Tyr-c(Asp-Ser-Lys-Pro-(D-Ala)-Arg-H...)Show SMILES CC[C@@H](C)[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](NC(=O)[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@H](CCCCN)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2cnc[nH]2)C(=O)N1)[C@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C100H161N33O26/c1-9-51(5)77(93(154)127-69(45-75(104)139)88(149)125-67(41-50(3)4)90(151)131-78(52(6)10-2)94(155)132-79(54(8)135)95(156)122-64(23-17-39-115-100(109)110)82(143)121-65(33-34-74(103)138)85(146)119-63(22-16-38-114-99(107)108)84(145)128-71(97(158)159)43-56-27-31-59(137)32-28-56)130-86(147)61-19-12-14-36-112-76(140)46-70(124-81(142)60(102)42-55-25-29-58(136)30-26-55)89(150)129-72(48-134)91(152)123-66(20-11-13-35-101)96(157)133-40-18-24-73(133)92(153)117-53(7)80(141)118-62(21-15-37-113-98(105)106)83(144)126-68(87(148)120-61)44-57-47-111-49-116-57/h25-32,47,49-54,60-73,77-79,134-137H,9-24,33-46,48,101-102H2,1-8H3,(H2,103,138)(H2,104,139)(H,111,116)(H,112,140)(H,117,153)(H,118,141)(H,119,146)(H,120,148)(H,121,143)(H,122,156)(H,123,152)(H,124,142)(H,125,149)(H,126,144)(H,127,154)(H,128,145)(H,129,150)(H,130,147)(H,131,151)(H,132,155)(H,158,159)(H4,105,106,113)(H4,107,108,114)(H4,109,110,115)/t51-,52-,53+,54+,60+,61+,62+,63-,64-,65-,66-,67-,68-,69-,70+,71-,72+,73+,77-,78-,79-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046553
(CHEMBL437421 | Tyr-Pro-Ser-Lys-Pro-(D-Ala)-Arg-His...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCNC(=O)CC[C@H](NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C105H161N33O26/c1-6-56(4)84-99(160)128-71(91(152)124-68(19-12-42-119-104(112)113)86(147)127-70(35-37-81(108)143)90(151)125-69(20-13-43-120-105(114)115)89(150)134-77(102(163)164)49-60-27-33-64(142)34-28-60)36-38-83(145)117-40-10-8-16-66(87(148)133-76(51-82(109)144)94(155)130-73(46-55(2)3)95(156)136-84)126-92(153)74(48-59-25-31-63(141)32-26-59)131-93(154)75(50-61-52-116-54-121-61)132-88(149)67(18-11-41-118-103(110)111)123-85(146)57(5)122-97(158)79-21-15-45-138(79)101(162)72(17-7-9-39-106)129-96(157)78(53-139)135-98(159)80-22-14-44-137(80)100(161)65(107)47-58-23-29-62(140)30-24-58/h23-34,52,54-57,65-80,84,139-142H,6-22,35-51,53,106-107H2,1-5H3,(H2,108,143)(H2,109,144)(H,116,121)(H,117,145)(H,122,158)(H,123,146)(H,124,152)(H,125,151)(H,126,153)(H,127,147)(H,128,160)(H,129,157)(H,130,155)(H,131,154)(H,132,149)(H,133,148)(H,134,150)(H,135,159)(H,136,156)(H,163,164)(H4,110,111,118)(H4,112,113,119)(H4,114,115,120)/t56-,57+,65+,66-,67-,68-,69-,70-,71-,72-,73+,74-,75-,76-,77-,78-,79+,80-,84-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046555
(CHEMBL429159 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-P...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)123(211)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)179-127(215)100(63-84-66-161-72-167-84)180-122(210)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(24-16-50-162-145(153)154)121(209)178-98(126(214)186-106)60-81-33-41-86(198)42-34-81)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,209)(H,179,215)(H,180,210)(H,181,224)(H,182,226)(H,183,211)(H,184,222)(H,185,225)(H,186,214)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76+,77+,78-,79+,89+,90-,91-,92-,93-,94-,95+,96-,97-,98+,99-,100-,101-,102-,103-,104-,105-,106-,107-,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50034125
(CHEMBL265849 | Neuropeptide Y(NPY)(13-36) | Pro-Al...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C135H208N40O37/c1-15-68(9)105(128(208)170-97(60-102(137)183)123(203)164-92(54-67(7)8)125(205)174-106(69(10)16-2)129(209)175-107(73(14)177)130(210)161-87(26-21-51-151-135(144)145)112(192)160-88(43-45-101(136)182)116(196)158-86(25-20-50-150-134(142)143)115(195)171-99(131(211)212)58-77-33-41-82(181)42-34-77)173-126(206)95(57-76-31-39-81(180)40-32-76)167-122(202)96(59-78-62-146-64-152-78)168-114(194)85(24-19-49-149-133(140)141)159-119(199)91(53-66(5)6)162-110(190)72(13)155-127(207)100(63-176)172-121(201)94(56-75-29-37-80(179)38-30-75)166-120(200)93(55-74-27-35-79(178)36-28-74)165-113(193)84(23-18-48-148-132(138)139)156-108(188)71(12)154-118(198)90(52-65(3)4)163-124(204)98(61-104(186)187)169-117(197)89(44-46-103(184)185)157-109(189)70(11)153-111(191)83-22-17-47-147-83/h27-42,62,64-73,83-100,105-107,147,176-181H,15-26,43-61,63H2,1-14H3,(H2,136,182)(H2,137,183)(H,146,152)(H,153,191)(H,154,198)(H,155,207)(H,156,188)(H,157,189)(H,158,196)(H,159,199)(H,160,192)(H,161,210)(H,162,190)(H,163,204)(H,164,203)(H,165,193)(H,166,200)(H,167,202)(H,168,194)(H,169,197)(H,170,208)(H,171,195)(H,172,201)(H,173,206)(H,174,205)(H,175,209)(H,184,185)(H,186,187)(H,211,212)(H4,138,139,148)(H4,140,141,149)(H4,142,143,150)(H4,144,145,151)/t68-,69-,70-,71-,72-,73+,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,105-,106-,107-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046546
(CHEMBL414051 | Tyr-Pro-Ser-Lys-Pro-(D-Ala)-Arg-His...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C104H162N32O26/c1-9-54(5)81(96(156)129-74(49-80(108)143)90(150)126-71(44-53(3)4)91(151)133-82(55(6)10-2)97(157)134-83(57(8)138)98(158)124-68(21-15-41-118-104(113)114)85(145)123-69(36-37-79(107)142)88(148)122-67(20-14-40-117-103(111)112)87(147)130-75(101(161)162)47-60-28-34-64(141)35-29-60)132-92(152)72(46-59-26-32-63(140)33-27-59)127-89(149)73(48-61-50-115-52-119-61)128-86(146)66(19-13-39-116-102(109)110)121-84(144)56(7)120-94(154)77-22-17-43-136(77)100(160)70(18-11-12-38-105)125-93(153)76(51-137)131-95(155)78-23-16-42-135(78)99(159)65(106)45-58-24-30-62(139)31-25-58/h24-35,50,52-57,65-78,81-83,137-141H,9-23,36-49,51,105-106H2,1-8H3,(H2,107,142)(H2,108,143)(H,115,119)(H,120,154)(H,121,144)(H,122,148)(H,123,145)(H,124,158)(H,125,153)(H,126,150)(H,127,149)(H,128,146)(H,129,156)(H,130,147)(H,131,155)(H,132,152)(H,133,151)(H,134,157)(H,161,162)(H4,109,110,116)(H4,111,112,117)(H4,113,114,118)/t54-,55-,56+,57+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046550
(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C102H161N31O25/c1-8-55(5)81(95(153)127-74(50-79(106)140)90(148)124-71(45-54(3)4)91(149)131-82(56(6)9-2)96(154)132-83(57(7)135)97(155)123-69(22-17-43-117-102(111)112)86(144)122-70(37-38-78(105)139)88(146)121-68(21-16-42-116-101(109)110)87(145)128-75(99(157)158)48-60-29-35-64(138)36-30-60)130-92(150)72(47-59-27-33-63(137)34-28-59)125-89(147)73(49-61-51-113-53-118-61)126-85(143)67(20-15-41-115-100(107)108)119-80(141)24-11-10-14-40-114-84(142)66(19-12-13-39-103)120-93(151)76(52-134)129-94(152)77-23-18-44-133(77)98(156)65(104)46-58-25-31-62(136)32-26-58/h25-36,51,53-57,65-77,81-83,134-138H,8-24,37-50,52,103-104H2,1-7H3,(H2,105,139)(H2,106,140)(H,113,118)(H,114,142)(H,119,141)(H,120,151)(H,121,146)(H,122,144)(H,123,155)(H,124,148)(H,125,147)(H,126,143)(H,127,153)(H,128,145)(H,129,152)(H,130,150)(H,131,149)(H,132,154)(H,157,158)(H4,107,108,115)(H4,109,110,116)(H4,111,112,117)/t55-,56-,57+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046543
(CHEMBL2370632 | Tyr-c((D-Glu)-Ser-Lys-Pro-(D-Ala)-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:28.61,86.88,70.72,33.34,101.103,121.123,147.151,17.18,8.9,43.45,63.66,wD:94.96,23.147,62.64,78.80,132.134,112.114,95.99,54.56,87.90,1.0,(-7.53,-.27,;-7.57,-2.13,;-8.61,-.98,;-10.04,-1.58,;-9.92,-3.08,;-8.39,-3.44,;-8.85,-4.89,;-10.39,-4.59,;-8.94,-6.4,;-10.5,-6.51,;-11.36,-5.23,;-12.91,-5.31,;-13.77,-4.04,;-15.32,-4.13,;-8.66,-7.9,;-8.01,-9.27,;-9.35,-10.06,;-7.05,-10.48,;-8.15,-11.54,;-9.66,-11.17,;-5.82,-11.41,;-4.4,-12.03,;-4.88,-13.5,;-2.86,-12.3,;-1.31,-12.22,;.18,-11.77,;.83,-13.13,;1.53,-10.98,;2.62,-9.92,;3.42,-8.61,;3.87,-7.16,;3.97,-5.65,;5.52,-5.55,;3.68,-4.14,;5.18,-3.7,;6.31,-4.73,;6.14,-6.24,;7.55,-6.86,;8.62,-5.75,;7.85,-4.42,;3.04,-2.75,;2.08,-1.56,;3.17,-.49,;.84,-.63,;1.66,.65,;3.2,.64,;4.03,1.92,;5.58,1.89,;6.38,3.2,;7.93,3.19,;5.62,4.53,;-.57,-.01,;-2.12,.26,;-2.02,1.78,;-3.67,.16,;-3.95,1.68,;-5.15,-.25,;-6.5,-1.04,;-7.44,.14,;3.86,-10.84,;3.63,-12.34,;5.3,-10.27,;6.52,-11.2,;6.3,-12.72,;7.54,-13.64,;4.87,-13.29,;4.65,-14.78,;7.96,-10.65,;8.17,-9.16,;9.2,-11.6,;10.64,-11.02,;10.86,-9.51,;12.3,-8.95,;13.53,-9.89,;12.51,-7.45,;11.88,-11.96,;11.65,-13.46,;13.32,-11.37,;14.54,-12.34,;14.33,-13.84,;15.56,-14.77,;17.02,-14.2,;15.33,-16.26,;15.99,-11.77,;16.19,-10.26,;17.23,-12.7,;18.66,-12.13,;18.88,-10.62,;20.32,-10.06,;17.64,-9.69,;17.84,-8.19,;19.88,-13.08,;19.67,-14.57,;21.32,-12.51,;22.56,-13.43,;22.36,-14.95,;20.91,-15.5,;23.58,-15.88,;24.01,-12.88,;24.21,-11.37,;25.24,-13.81,;26.68,-13.25,;26.9,-11.72,;28.35,-11.17,;28.57,-9.69,;30,-9.1,;30.23,-7.59,;31.67,-7.03,;28.97,-6.66,;27.9,-14.18,;27.69,-15.68,;29.34,-13.61,;30.58,-14.54,;30.38,-16.05,;31.6,-16.98,;31.38,-18.5,;29.95,-19.07,;32.61,-19.45,;32.03,-13.99,;32.24,-12.47,;33.26,-14.92,;34.71,-14.37,;34.92,-12.85,;36.37,-12.27,;36.6,-10.78,;38.02,-10.23,;38.25,-8.71,;39.69,-8.14,;37.02,-7.76,;35.92,-15.3,;35.71,-16.8,;37.39,-14.73,;38.6,-15.68,;38.4,-17.16,;39.63,-18.11,;39.4,-19.6,;40.64,-20.53,;42.08,-19.98,;43.31,-20.91,;42.29,-18.46,;41.07,-17.54,;40.05,-15.11,;41.28,-16.04,;40.26,-13.6,;-2.95,-13.82,;-1.64,-14.67,;-.26,-13.99,;-1.74,-16.18,;-.44,-17.02,;-3.13,-16.85,;-3.99,-18.19,;-5.57,-18.25,;-6.36,-19.53,;-5.61,-20.79,;-6.43,-22.07,;-4.06,-20.74,;-3.24,-19.52,)| Show InChI InChI=1S/C97H155N33O26/c1-9-48(5)74(90(151)124-65(41-72(101)136)84(145)122-63(37-47(3)4)86(147)127-75(49(6)10-2)91(152)129-76(51(8)132)92(153)119-60(20-15-35-111-97(106)107)80(141)118-61(30-31-71(100)135)83(144)117-59(19-14-34-110-96(104)105)82(143)125-67(94(155)156)39-53-24-28-56(134)29-25-53)128-87(148)68-44-112-79(140)64(40-54-43-108-46-113-54)123-81(142)58(18-13-33-109-95(102)103)116-77(138)50(7)114-89(150)70-21-16-36-130(70)93(154)62(17-11-12-32-98)120-88(149)69(45-131)126-85(146)66(42-73(137)115-68)121-78(139)57(99)38-52-22-26-55(133)27-23-52/h22-29,43,46-51,57-70,74-76,131-134H,9-21,30-42,44-45,98-99H2,1-8H3,(H2,100,135)(H2,101,136)(H,108,113)(H,112,140)(H,114,150)(H,115,137)(H,116,138)(H,117,144)(H,118,141)(H,119,153)(H,120,149)(H,121,139)(H,122,145)(H,123,142)(H,124,151)(H,125,143)(H,126,146)(H,127,147)(H,128,148)(H,129,152)(H,155,156)(H4,102,103,109)(H4,104,105,110)(H4,106,107,111)/t48-,49-,50+,51+,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,74-,75-,76-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046554
(CHEMBL437656 | Tyr-Pro-Ser-Lys-Pro-Asp-c(Cys-Pro-G...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)123(211)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)179-127(215)100(63-84-66-161-72-167-84)180-122(210)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(24-16-50-162-145(153)154)121(209)178-98(126(214)186-106)60-81-33-41-86(198)42-34-81)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,209)(H,179,215)(H,180,210)(H,181,224)(H,182,226)(H,183,211)(H,184,222)(H,185,225)(H,186,214)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76+,77+,78-,79+,89+,90-,91-,92-,93-,94-,95+,96-,97-,98+,99-,100-,101-,102-,103-,104-,105-,106+,107+,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046545
(CHEMBL263848 | Tyr-Pro-Ser-Lys-Pro-Asp-c(Cys-Pro-G...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)122(210)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)178-127(215)100(63-84-66-161-72-167-84)180-121(209)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-126(214)98(60-81-33-41-86(198)42-34-81)179-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(123(211)186-106)24-16-50-162-145(153)154)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,215)(H,179,222)(H,180,209)(H,181,224)(H,182,226)(H,183,210)(H,184,214)(H,185,225)(H,186,211)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76-,77+,78-,79+,89+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107+,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50034128
(CHEMBL441396 | Neuropeptide Y(NPY) | Tyr-Pro-Ser-L...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C190H286N54O58/c1-16-94(9)149(179(294)233-128(81-141(194)254)168(283)225-123(74-93(7)8)171(286)239-150(95(10)17-2)180(295)240-151(100(15)247)181(296)221-116(32-23-67-208-190(202)203)155(270)220-118(57-60-140(193)253)160(275)218-115(31-22-66-207-189(200)201)158(273)235-133(186(301)302)79-105-45-55-111(252)56-46-105)238-172(287)126(78-104-43-53-110(251)54-44-104)228-167(282)127(80-106-86-204-90-210-106)229-157(272)114(30-21-65-206-188(198)199)219-164(279)122(73-92(5)6)223-154(269)97(12)212-173(288)134(88-245)236-166(281)125(77-103-41-51-109(250)52-42-103)227-165(280)124(76-102-39-49-108(249)50-40-102)226-156(271)113(29-20-64-205-187(196)197)216-152(267)96(11)211-162(277)121(72-91(3)4)224-169(284)130(84-147(263)264)231-161(276)119(59-62-145(259)260)217-153(268)98(13)213-176(291)137-34-25-68-241(137)182(297)99(14)214-163(278)129(83-146(261)262)230-159(274)117(58-61-144(257)258)215-143(256)87-209-175(290)136-33-24-70-243(136)185(300)132(82-142(195)255)234-170(285)131(85-148(265)266)232-177(292)139-36-27-71-244(139)184(299)120(28-18-19-63-191)222-174(289)135(89-246)237-178(293)138-35-26-69-242(138)183(298)112(192)75-101-37-47-107(248)48-38-101/h37-56,86,90-100,112-139,149-151,245-252H,16-36,57-85,87-89,191-192H2,1-15H3,(H2,193,253)(H2,194,254)(H2,195,255)(H,204,210)(H,209,290)(H,211,277)(H,212,288)(H,213,291)(H,214,278)(H,215,256)(H,216,267)(H,217,268)(H,218,275)(H,219,279)(H,220,270)(H,221,296)(H,222,289)(H,223,269)(H,224,284)(H,225,283)(H,226,271)(H,227,280)(H,228,282)(H,229,272)(H,230,274)(H,231,276)(H,232,292)(H,233,294)(H,234,285)(H,235,273)(H,236,281)(H,237,293)(H,238,287)(H,239,286)(H,240,295)(H,257,258)(H,259,260)(H,261,262)(H,263,264)(H,265,266)(H,301,302)(H4,196,197,205)(H4,198,199,206)(H4,200,201,207)(H4,202,203,208)/t94-,95-,96-,97-,98-,99-,100+,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,149-,150-,151-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046542
(CHEMBL411979 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-P...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)123(211)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)179-127(215)100(63-84-66-161-72-167-84)180-122(210)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(24-16-50-162-145(153)154)121(209)178-98(126(214)186-106)60-81-33-41-86(198)42-34-81)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,209)(H,179,215)(H,180,210)(H,181,224)(H,182,226)(H,183,211)(H,184,222)(H,185,225)(H,186,214)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76+,77+,78-,79+,89+,90-,91-,92-,93-,94-,95+,96-,97-,98+,99-,100-,101-,102-,103-,104-,105-,106+,107-,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046544
(CHEMBL409634 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C146H227N43O38S2/c1-11-77(7)115(137(221)179-102(67-112(150)198)128(212)174-98(61-76(5)6)130(214)186-116(78(8)12-2)138(222)187-117(80(10)192)139(223)171-94(30-23-57-164-146(157)158)121(205)170-95(50-51-111(149)197)124(208)168-93(29-22-56-163-145(155)156)123(207)180-104(142(226)227)65-84-40-48-89(196)49-41-84)185-131(215)100(64-83-38-46-88(195)47-39-83)175-127(211)101(66-85-69-159-74-165-85)177-122(206)92(28-21-55-162-144(153)154)169-125(209)97(60-75(3)4)173-118(202)79(9)166-132(216)105(70-190)181-126(210)99(63-82-36-44-87(194)45-37-82)176-134(218)108-73-229-228-72-107(119(203)160-53-19-15-13-14-16-33-113(199)167-91(120(204)184-108)27-20-54-161-143(151)152)183-129(213)103(68-114(200)201)178-135(219)110-32-25-59-189(110)141(225)96(26-17-18-52-147)172-133(217)106(71-191)182-136(220)109-31-24-58-188(109)140(224)90(148)62-81-34-42-86(193)43-35-81/h34-49,69,74-80,90-110,115-117,190-196H,11-33,50-68,70-73,147-148H2,1-10H3,(H2,149,197)(H2,150,198)(H,159,165)(H,160,203)(H,166,216)(H,167,199)(H,168,208)(H,169,209)(H,170,205)(H,171,223)(H,172,217)(H,173,202)(H,174,212)(H,175,211)(H,176,218)(H,177,206)(H,178,219)(H,179,221)(H,180,207)(H,181,210)(H,182,220)(H,183,213)(H,184,204)(H,185,215)(H,186,214)(H,187,222)(H,200,201)(H,226,227)(H4,151,152,161)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)/t77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96+,97-,98-,99-,100-,101+,102-,103-,104-,105-,106+,107-,108+,109+,110-,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046558
(CHEMBL266730 | Tyr-Pro-Ser-Lys-Pro-Gly-Arg-His-Tyr...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C103H160N32O26/c1-8-54(5)81(95(155)128-73(48-79(107)142)89(149)125-70(43-53(3)4)90(150)132-82(55(6)9-2)96(156)133-83(56(7)137)97(157)123-67(20-14-40-117-103(112)113)85(145)122-68(35-36-78(106)141)87(147)121-66(19-13-39-116-102(110)111)86(146)129-74(100(160)161)46-59-27-33-63(140)34-28-59)131-91(151)71(45-58-25-31-62(139)32-26-58)126-88(148)72(47-60-49-114-52-119-60)127-84(144)65(18-12-38-115-101(108)109)120-80(143)50-118-93(153)76-21-15-42-135(76)99(159)69(17-10-11-37-104)124-92(152)75(51-136)130-94(154)77-22-16-41-134(77)98(158)64(105)44-57-23-29-61(138)30-24-57/h23-34,49,52-56,64-77,81-83,136-140H,8-22,35-48,50-51,104-105H2,1-7H3,(H2,106,141)(H2,107,142)(H,114,119)(H,118,153)(H,120,143)(H,121,147)(H,122,145)(H,123,157)(H,124,152)(H,125,149)(H,126,148)(H,127,144)(H,128,155)(H,129,146)(H,130,154)(H,131,151)(H,132,150)(H,133,156)(H,160,161)(H4,108,109,115)(H4,110,111,116)(H4,112,113,117)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046541
(CHEMBL427966 | Tyr-Pro-Ser-Lys-Pro-Asp-c(Glu-Pro-(...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C151H233N45O40/c1-12-78(7)118(141(229)187-106(70-115(155)205)132(220)182-102(64-77(5)6)134(222)192-119(79(8)13-2)142(230)193-120(82(11)199)143(231)178-97(30-21-59-169-151(162)163)124(212)177-98(50-52-114(154)204)128(216)175-96(29-20-58-168-150(160)161)127(215)188-108(147(235)236)68-86-40-48-91(203)49-41-86)191-135(223)104(67-85-38-46-90(202)47-39-85)184-131(219)105(69-87-72-164-75-170-87)185-126(214)95(28-19-57-167-149(158)159)176-129(217)101(63-76(3)4)181-122(210)80(9)171-136(224)109(73-197)189-130(218)103(66-84-36-44-89(201)45-37-84)183-125(213)93-25-15-17-55-165-116(206)53-51-100(146(234)195-61-23-31-111(195)138(226)172-81(10)121(209)173-94(123(211)174-93)27-18-56-166-148(156)157)180-133(221)107(71-117(207)208)186-139(227)113-33-24-62-196(113)145(233)99(26-14-16-54-152)179-137(225)110(74-198)190-140(228)112-32-22-60-194(112)144(232)92(153)65-83-34-42-88(200)43-35-83/h34-49,72,75-82,92-113,118-120,197-203H,12-33,50-71,73-74,152-153H2,1-11H3,(H2,154,204)(H2,155,205)(H,164,170)(H,165,206)(H,171,224)(H,172,226)(H,173,209)(H,174,211)(H,175,216)(H,176,217)(H,177,212)(H,178,231)(H,179,225)(H,180,221)(H,181,210)(H,182,220)(H,183,213)(H,184,219)(H,185,214)(H,186,227)(H,187,229)(H,188,215)(H,189,218)(H,190,228)(H,191,223)(H,192,222)(H,193,230)(H,207,208)(H,235,236)(H4,156,157,166)(H4,158,159,167)(H4,160,161,168)(H4,162,163,169)/t78-,79-,80-,81+,82+,92-,93-,94+,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111+,112-,113+,118-,119-,120-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046554
(CHEMBL437656 | Tyr-Pro-Ser-Lys-Pro-Asp-c(Cys-Pro-G...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H]1CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)123(211)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)179-127(215)100(63-84-66-161-72-167-84)180-122(210)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(24-16-50-162-145(153)154)121(209)178-98(126(214)186-106)60-81-33-41-86(198)42-34-81)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,209)(H,179,215)(H,180,210)(H,181,224)(H,182,226)(H,183,211)(H,184,222)(H,185,225)(H,186,214)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76+,77+,78-,79+,89+,90-,91-,92-,93-,94-,95+,96-,97-,98+,99-,100-,101-,102-,103-,104-,105-,106+,107+,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046540
(CHEMBL437671 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C146H227N43O38S2/c1-11-77(7)115(137(221)179-102(67-112(150)198)128(212)174-98(61-76(5)6)130(214)186-116(78(8)12-2)138(222)187-117(80(10)192)139(223)171-94(30-23-57-164-146(157)158)121(205)170-95(50-51-111(149)197)124(208)168-93(29-22-56-163-145(155)156)123(207)180-104(142(226)227)65-84-40-48-89(196)49-41-84)185-131(215)100(64-83-38-46-88(195)47-39-83)176-127(211)101(66-85-69-159-74-165-85)177-122(206)92(28-21-55-162-144(153)154)169-125(209)97(60-75(3)4)173-118(202)79(9)166-132(216)105(70-190)181-134(218)108-73-229-228-72-107(119(203)160-53-19-15-13-14-16-33-113(199)167-91(27-20-54-161-143(151)152)120(204)175-99(126(210)184-108)63-82-36-44-87(194)45-37-82)183-129(213)103(68-114(200)201)178-135(219)110-32-25-59-189(110)141(225)96(26-17-18-52-147)172-133(217)106(71-191)182-136(220)109-31-24-58-188(109)140(224)90(148)62-81-34-42-86(193)43-35-81/h34-49,69,74-80,90-110,115-117,190-196H,11-33,50-68,70-73,147-148H2,1-10H3,(H2,149,197)(H2,150,198)(H,159,165)(H,160,203)(H,166,216)(H,167,199)(H,168,208)(H,169,209)(H,170,205)(H,171,223)(H,172,217)(H,173,202)(H,174,212)(H,175,204)(H,176,211)(H,177,206)(H,178,219)(H,179,221)(H,180,207)(H,181,218)(H,182,220)(H,183,213)(H,184,210)(H,185,215)(H,186,214)(H,187,222)(H,200,201)(H,226,227)(H4,151,152,161)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)/t77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99+,100-,101-,102-,103+,104-,105-,106-,107-,108+,109+,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046547
(CHEMBL440824 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C146H227N43O38S2/c1-11-77(7)115(137(221)179-102(67-112(150)198)128(212)174-98(61-76(5)6)130(214)186-116(78(8)12-2)138(222)187-117(80(10)192)139(223)171-94(30-23-57-164-146(157)158)121(205)170-95(50-51-111(149)197)124(208)168-93(29-22-56-163-145(155)156)123(207)180-104(142(226)227)65-84-40-48-89(196)49-41-84)185-131(215)100(64-83-38-46-88(195)47-39-83)176-127(211)101(66-85-69-159-74-165-85)177-122(206)92(28-21-55-162-144(153)154)169-125(209)97(60-75(3)4)173-118(202)79(9)166-132(216)105(70-190)181-134(218)108-73-229-228-72-107(119(203)160-53-19-15-13-14-16-33-113(199)167-91(27-20-54-161-143(151)152)120(204)175-99(126(210)184-108)63-82-36-44-87(194)45-37-82)183-129(213)103(68-114(200)201)178-135(219)110-32-25-59-189(110)141(225)96(26-17-18-52-147)172-133(217)106(71-191)182-136(220)109-31-24-58-188(109)140(224)90(148)62-81-34-42-86(193)43-35-81/h34-49,69,74-80,90-110,115-117,190-196H,11-33,50-68,70-73,147-148H2,1-10H3,(H2,149,197)(H2,150,198)(H,159,165)(H,160,203)(H,166,216)(H,167,199)(H,168,208)(H,169,209)(H,170,205)(H,171,223)(H,172,217)(H,173,202)(H,174,212)(H,175,204)(H,176,211)(H,177,206)(H,178,219)(H,179,221)(H,180,207)(H,181,218)(H,182,220)(H,183,213)(H,184,210)(H,185,215)(H,186,214)(H,187,222)(H,200,201)(H,226,227)(H4,151,152,161)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)/t77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99+,100-,101-,102-,103+,104-,105-,106-,107-,108-,109+,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046544
(CHEMBL409634 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C146H227N43O38S2/c1-11-77(7)115(137(221)179-102(67-112(150)198)128(212)174-98(61-76(5)6)130(214)186-116(78(8)12-2)138(222)187-117(80(10)192)139(223)171-94(30-23-57-164-146(157)158)121(205)170-95(50-51-111(149)197)124(208)168-93(29-22-56-163-145(155)156)123(207)180-104(142(226)227)65-84-40-48-89(196)49-41-84)185-131(215)100(64-83-38-46-88(195)47-39-83)175-127(211)101(66-85-69-159-74-165-85)177-122(206)92(28-21-55-162-144(153)154)169-125(209)97(60-75(3)4)173-118(202)79(9)166-132(216)105(70-190)181-126(210)99(63-82-36-44-87(194)45-37-82)176-134(218)108-73-229-228-72-107(119(203)160-53-19-15-13-14-16-33-113(199)167-91(120(204)184-108)27-20-54-161-143(151)152)183-129(213)103(68-114(200)201)178-135(219)110-32-25-59-189(110)141(225)96(26-17-18-52-147)172-133(217)106(71-191)182-136(220)109-31-24-58-188(109)140(224)90(148)62-81-34-42-86(193)43-35-81/h34-49,69,74-80,90-110,115-117,190-196H,11-33,50-68,70-73,147-148H2,1-10H3,(H2,149,197)(H2,150,198)(H,159,165)(H,160,203)(H,166,216)(H,167,199)(H,168,208)(H,169,209)(H,170,205)(H,171,223)(H,172,217)(H,173,202)(H,174,212)(H,175,211)(H,176,218)(H,177,206)(H,178,219)(H,179,221)(H,180,207)(H,181,210)(H,182,220)(H,183,213)(H,184,204)(H,185,215)(H,186,214)(H,187,222)(H,200,201)(H,226,227)(H4,151,152,161)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)/t77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96+,97-,98-,99-,100-,101+,102-,103-,104-,105-,106+,107-,108+,109+,110-,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046547
(CHEMBL440824 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C146H227N43O38S2/c1-11-77(7)115(137(221)179-102(67-112(150)198)128(212)174-98(61-76(5)6)130(214)186-116(78(8)12-2)138(222)187-117(80(10)192)139(223)171-94(30-23-57-164-146(157)158)121(205)170-95(50-51-111(149)197)124(208)168-93(29-22-56-163-145(155)156)123(207)180-104(142(226)227)65-84-40-48-89(196)49-41-84)185-131(215)100(64-83-38-46-88(195)47-39-83)176-127(211)101(66-85-69-159-74-165-85)177-122(206)92(28-21-55-162-144(153)154)169-125(209)97(60-75(3)4)173-118(202)79(9)166-132(216)105(70-190)181-134(218)108-73-229-228-72-107(119(203)160-53-19-15-13-14-16-33-113(199)167-91(27-20-54-161-143(151)152)120(204)175-99(126(210)184-108)63-82-36-44-87(194)45-37-82)183-129(213)103(68-114(200)201)178-135(219)110-32-25-59-189(110)141(225)96(26-17-18-52-147)172-133(217)106(71-191)182-136(220)109-31-24-58-188(109)140(224)90(148)62-81-34-42-86(193)43-35-81/h34-49,69,74-80,90-110,115-117,190-196H,11-33,50-68,70-73,147-148H2,1-10H3,(H2,149,197)(H2,150,198)(H,159,165)(H,160,203)(H,166,216)(H,167,199)(H,168,208)(H,169,209)(H,170,205)(H,171,223)(H,172,217)(H,173,202)(H,174,212)(H,175,204)(H,176,211)(H,177,206)(H,178,219)(H,179,221)(H,180,207)(H,181,218)(H,182,220)(H,183,213)(H,184,210)(H,185,215)(H,186,214)(H,187,222)(H,200,201)(H,226,227)(H4,151,152,161)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)/t77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99+,100-,101-,102-,103+,104-,105-,106-,107-,108-,109+,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046545
(CHEMBL263848 | Tyr-Pro-Ser-Lys-Pro-Asp-c(Cys-Pro-G...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)122(210)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)178-127(215)100(63-84-66-161-72-167-84)180-121(209)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-126(214)98(60-81-33-41-86(198)42-34-81)179-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(123(211)186-106)24-16-50-162-145(153)154)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,215)(H,179,222)(H,180,209)(H,181,224)(H,182,226)(H,183,210)(H,184,214)(H,185,225)(H,186,211)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76-,77+,78-,79+,89+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107+,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046555
(CHEMBL429159 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-P...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)123(211)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)179-127(215)100(63-84-66-161-72-167-84)180-122(210)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(24-16-50-162-145(153)154)121(209)178-98(126(214)186-106)60-81-33-41-86(198)42-34-81)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,209)(H,179,215)(H,180,210)(H,181,224)(H,182,226)(H,183,211)(H,184,222)(H,185,225)(H,186,214)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76+,77+,78-,79+,89+,90-,91-,92-,93-,94-,95+,96-,97-,98+,99-,100-,101-,102-,103-,104-,105-,106-,107-,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046540
(CHEMBL437671 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-A...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C146H227N43O38S2/c1-11-77(7)115(137(221)179-102(67-112(150)198)128(212)174-98(61-76(5)6)130(214)186-116(78(8)12-2)138(222)187-117(80(10)192)139(223)171-94(30-23-57-164-146(157)158)121(205)170-95(50-51-111(149)197)124(208)168-93(29-22-56-163-145(155)156)123(207)180-104(142(226)227)65-84-40-48-89(196)49-41-84)185-131(215)100(64-83-38-46-88(195)47-39-83)176-127(211)101(66-85-69-159-74-165-85)177-122(206)92(28-21-55-162-144(153)154)169-125(209)97(60-75(3)4)173-118(202)79(9)166-132(216)105(70-190)181-134(218)108-73-229-228-72-107(119(203)160-53-19-15-13-14-16-33-113(199)167-91(27-20-54-161-143(151)152)120(204)175-99(126(210)184-108)63-82-36-44-87(194)45-37-82)183-129(213)103(68-114(200)201)178-135(219)110-32-25-59-189(110)141(225)96(26-17-18-52-147)172-133(217)106(71-191)182-136(220)109-31-24-58-188(109)140(224)90(148)62-81-34-42-86(193)43-35-81/h34-49,69,74-80,90-110,115-117,190-196H,11-33,50-68,70-73,147-148H2,1-10H3,(H2,149,197)(H2,150,198)(H,159,165)(H,160,203)(H,166,216)(H,167,199)(H,168,208)(H,169,209)(H,170,205)(H,171,223)(H,172,217)(H,173,202)(H,174,212)(H,175,204)(H,176,211)(H,177,206)(H,178,219)(H,179,221)(H,180,207)(H,181,218)(H,182,220)(H,183,213)(H,184,210)(H,185,215)(H,186,214)(H,187,222)(H,200,201)(H,226,227)(H4,151,152,161)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)/t77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99+,100-,101-,102-,103+,104-,105-,106-,107-,108+,109+,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 87 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046541
(CHEMBL427966 | Tyr-Pro-Ser-Lys-Pro-Asp-c(Glu-Pro-(...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C151H233N45O40/c1-12-78(7)118(141(229)187-106(70-115(155)205)132(220)182-102(64-77(5)6)134(222)192-119(79(8)13-2)142(230)193-120(82(11)199)143(231)178-97(30-21-59-169-151(162)163)124(212)177-98(50-52-114(154)204)128(216)175-96(29-20-58-168-150(160)161)127(215)188-108(147(235)236)68-86-40-48-91(203)49-41-86)191-135(223)104(67-85-38-46-90(202)47-39-85)184-131(219)105(69-87-72-164-75-170-87)185-126(214)95(28-19-57-167-149(158)159)176-129(217)101(63-76(3)4)181-122(210)80(9)171-136(224)109(73-197)189-130(218)103(66-84-36-44-89(201)45-37-84)183-125(213)93-25-15-17-55-165-116(206)53-51-100(146(234)195-61-23-31-111(195)138(226)172-81(10)121(209)173-94(123(211)174-93)27-18-56-166-148(156)157)180-133(221)107(71-117(207)208)186-139(227)113-33-24-62-196(113)145(233)99(26-14-16-54-152)179-137(225)110(74-198)190-140(228)112-32-22-60-194(112)144(232)92(153)65-83-34-42-88(200)43-35-83/h34-49,72,75-82,92-113,118-120,197-203H,12-33,50-71,73-74,152-153H2,1-11H3,(H2,154,204)(H2,155,205)(H,164,170)(H,165,206)(H,171,224)(H,172,226)(H,173,209)(H,174,211)(H,175,216)(H,176,217)(H,177,212)(H,178,231)(H,179,225)(H,180,221)(H,181,210)(H,182,220)(H,183,213)(H,184,219)(H,185,214)(H,186,227)(H,187,229)(H,188,215)(H,189,218)(H,190,228)(H,191,223)(H,192,222)(H,193,230)(H,207,208)(H,235,236)(H4,156,157,166)(H4,158,159,167)(H4,160,161,168)(H4,162,163,169)/t78-,79-,80-,81+,82+,92-,93-,94+,95-,96-,97-,98-,99-,100+,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111+,112-,113+,118-,119-,120-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046556
(CHEMBL2370633 | Tyr-c(Glu-Ser-Lys-Pro-(D-Ala)-Arg-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:94.96,29.61,62.64,78.80,132.134,34.35,112.114,147.151,17.18,95.99,8.9,44.46,87.90,wD:86.88,70.72,23.147,101.103,121.123,63.66,1.0,(-3.99,-11.35,;-2.23,-11.99,;-3.67,-12.59,;-3.55,-14.14,;-2.04,-14.49,;-1.22,-13.16,;.03,-14.06,;-.75,-15.42,;1.46,-14.65,;1.02,-16.14,;-.49,-16.53,;-.93,-18.03,;-2.45,-18.41,;-2.89,-19.91,;2.98,-14.89,;4.54,-14.77,;4.82,-16.3,;6.03,-14.29,;6.66,-15.71,;5.73,-16.97,;7.38,-13.5,;8.51,-12.41,;9.7,-13.39,;9.36,-11.09,;9.89,-9.62,;10.05,-8.08,;9.87,-6.55,;11.38,-6.16,;9.33,-5.1,;8.47,-3.82,;7.34,-2.77,;5.98,-2.02,;4.48,-1.61,;4.75,-.08,;2.94,-1.55,;2.84,,;4.14,.88,;5.59,.36,;6.57,1.59,;5.69,2.87,;4.2,2.43,;1.4,-1.84,;-.02,-2.49,;-.8,-1.15,;-1.26,-3.43,;-2.33,-2.32,;-1.89,-.83,;-2.97,.28,;-2.53,1.77,;-3.61,2.88,;-3.16,4.38,;-5.13,2.5,;-2.26,-4.64,;-2.95,-6.05,;-4.42,-5.54,;-3.31,-7.55,;-3.31,-9.11,;-2.93,-10.61,;-4.4,-11.16,;9.66,-2.79,;9.38,-1.28,;11.64,-2.7,;12.82,-2.16,;12.93,-.63,;14.12,-.1,;11.88,.37,;12.01,1.9,;13.87,-3.16,;13.76,-4.69,;15.06,-2.62,;16.11,-3.63,;15.99,-5.16,;16.81,-6.05,;18.4,-6.28,;16.34,-7.55,;17.3,-3.09,;17.42,-1.57,;18.35,-4.09,;19.54,-3.56,;19.66,-2.03,;20.84,-1.49,;21.9,-2.49,;20.97,.04,;20.59,-4.56,;20.47,-6.08,;21.78,-4.03,;22.83,-5.03,;22.71,-6.55,;23.77,-7.55,;21.53,-7.09,;21.4,-8.62,;24.02,-4.5,;24.15,-2.96,;25.07,-5.49,;26.26,-4.96,;26.38,-3.43,;25.33,-2.43,;27.57,-2.9,;27.32,-5.96,;27.2,-7.5,;28.5,-5.43,;29.56,-6.42,;29.44,-7.96,;30.49,-8.96,;30.37,-10.49,;31.43,-11.48,;31.3,-13.02,;32.37,-14.02,;30.13,-13.55,;30.73,-5.9,;30.87,-4.37,;31.8,-6.89,;32.97,-6.36,;33.11,-4.82,;34.29,-4.3,;34.4,-2.77,;33.35,-1.77,;35.59,-2.23,;34.04,-7.36,;33.91,-8.89,;35.23,-6.83,;36.28,-7.83,;36.15,-9.36,;37.21,-10.36,;37.09,-11.89,;38.15,-12.89,;38.03,-14.42,;39.08,-15.42,;36.84,-14.95,;37.46,-7.29,;37.58,-5.76,;38.52,-8.29,;39.7,-7.76,;39.82,-6.22,;41.01,-5.69,;41.13,-4.16,;42.31,-3.64,;43.37,-4.63,;44.55,-4.1,;43.25,-6.16,;42.06,-6.69,;40.76,-8.76,;41.93,-8.23,;40.63,-10.29,;10.75,-11.77,;12.05,-10.88,;11.95,-9.34,;13.44,-11.56,;14.74,-10.68,;13.54,-13.1,;14.8,-14.29,;14.7,-15.85,;15.96,-16.75,;17.33,-16.09,;18.59,-16.98,;17.43,-14.53,;16.17,-13.63,)| Show InChI InChI=1S/C97H155N33O26/c1-8-49(5)75(90(151)124-66(42-72(101)136)85(146)122-64(38-48(3)4)86(147)127-76(50(6)9-2)91(152)129-77(51(7)132)92(153)120-60(19-14-36-111-97(106)107)81(142)119-61(29-31-71(100)135)83(144)118-59(18-13-35-110-96(104)105)82(143)125-67(94(155)156)40-53-23-27-56(134)28-24-53)128-87(148)68-44-112-79(140)65(41-54-43-108-47-114-54)123-80(141)58(17-12-34-109-95(102)103)115-74(138)45-113-89(150)70-20-15-37-130(70)93(154)63(16-10-11-33-98)121-88(149)69(46-131)126-84(145)62(30-32-73(137)116-68)117-78(139)57(99)39-52-21-25-55(133)26-22-52/h21-28,43,47-51,57-70,75-77,131-134H,8-20,29-42,44-46,98-99H2,1-7H3,(H2,100,135)(H2,101,136)(H,108,114)(H,112,140)(H,113,150)(H,115,138)(H,116,137)(H,117,139)(H,118,144)(H,119,142)(H,120,153)(H,121,149)(H,122,146)(H,123,141)(H,124,151)(H,125,143)(H,126,145)(H,127,147)(H,128,148)(H,129,152)(H,155,156)(H4,102,103,109)(H4,104,105,110)(H4,106,107,111)/t49-,50-,51+,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046558
(CHEMBL266730 | Tyr-Pro-Ser-Lys-Pro-Gly-Arg-His-Tyr...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C103H160N32O26/c1-8-54(5)81(95(155)128-73(48-79(107)142)89(149)125-70(43-53(3)4)90(150)132-82(55(6)9-2)96(156)133-83(56(7)137)97(157)123-67(20-14-40-117-103(112)113)85(145)122-68(35-36-78(106)141)87(147)121-66(19-13-39-116-102(110)111)86(146)129-74(100(160)161)46-59-27-33-63(140)34-28-59)131-91(151)71(45-58-25-31-62(139)32-26-58)126-88(148)72(47-60-49-114-52-119-60)127-84(144)65(18-12-38-115-101(108)109)120-80(143)50-118-93(153)76-21-15-42-135(76)99(159)69(17-10-11-37-104)124-92(152)75(51-136)130-94(154)77-22-16-41-134(77)98(158)64(105)44-57-23-29-61(138)30-24-57/h23-34,49,52-56,64-77,81-83,136-140H,8-22,35-48,50-51,104-105H2,1-7H3,(H2,106,141)(H2,107,142)(H,114,119)(H,118,153)(H,120,143)(H,121,147)(H,122,145)(H,123,157)(H,124,152)(H,125,149)(H,126,148)(H,127,144)(H,128,155)(H,129,146)(H,130,154)(H,131,151)(H,132,150)(H,133,156)(H,160,161)(H4,108,109,115)(H4,110,111,116)(H4,112,113,117)/t54-,55-,56+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046542
(CHEMBL411979 | Tyr-Pro-Ser-Lys-Pro-Asp-c((D-Cys)-P...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C148H227N45O40S2/c1-12-75(7)115(138(226)182-101(64-112(152)202)128(216)177-97(58-74(5)6)130(218)189-116(76(8)13-2)139(227)190-117(79(11)196)140(228)174-93(27-19-53-165-148(159)160)120(208)173-94(47-48-111(151)201)124(212)171-92(26-18-52-164-147(157)158)123(211)183-103(144(232)233)62-83-37-45-88(200)46-38-83)188-131(219)99(61-82-35-43-87(199)44-36-82)179-127(215)100(63-84-66-161-72-167-84)180-122(210)91(25-17-51-163-146(155)156)172-125(213)96(57-73(3)4)176-119(207)78(10)169-132(220)104(68-194)184-134(222)106-70-234-235-71-107(143(231)192-55-20-28-108(192)135(223)166-67-113(203)168-77(9)118(206)170-90(24-16-50-162-145(153)154)121(209)178-98(126(214)186-106)60-81-33-41-86(198)42-34-81)187-129(217)102(65-114(204)205)181-136(224)110-30-22-56-193(110)142(230)95(23-14-15-49-149)175-133(221)105(69-195)185-137(225)109-29-21-54-191(109)141(229)89(150)59-80-31-39-85(197)40-32-80/h31-46,66,72-79,89-110,115-117,194-200H,12-30,47-65,67-71,149-150H2,1-11H3,(H2,151,201)(H2,152,202)(H,161,167)(H,166,223)(H,168,203)(H,169,220)(H,170,206)(H,171,212)(H,172,213)(H,173,208)(H,174,228)(H,175,221)(H,176,207)(H,177,216)(H,178,209)(H,179,215)(H,180,210)(H,181,224)(H,182,226)(H,183,211)(H,184,222)(H,185,225)(H,186,214)(H,187,217)(H,188,219)(H,189,218)(H,190,227)(H,204,205)(H,232,233)(H4,153,154,162)(H4,155,156,163)(H4,157,158,164)(H4,159,160,165)/t75-,76+,77+,78-,79+,89+,90-,91-,92-,93-,94-,95+,96-,97-,98+,99-,100-,101-,102-,103-,104-,105-,106+,107-,108+,109-,110+,115-,116-,117-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046557
(CHEMBL2370624 | Tyr-c(Glu-Ser-Lys-(Aca)-Arg-His-(D...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CNC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |wU:103.105,28.27,24.24,8.12,141.143,33.33,121.123,86.88,71.72,104.108,43.44,62.63,2.2,wD:4.4,16.20,77.84,110.112,130.132,96.99,(21.68,-18.1,;21.68,-16.56,;23.04,-15.83,;24.37,-16.63,;23.04,-14.3,;21.7,-13.51,;20.32,-14.27,;20.34,-15.77,;18.99,-13.47,;18.99,-11.94,;20.35,-11.22,;20.38,-9.68,;21.72,-12.01,;17.63,-14.19,;16.3,-13.41,;16.3,-11.89,;14.93,-14.12,;14.91,-15.66,;16.27,-16.45,;17.62,-15.72,;16.26,-17.95,;13.59,-13.33,;12.22,-14.07,;12.21,-15.59,;10.9,-13.29,;9.25,-14.34,;8.14,-13.26,;8.54,-11.79,;6.64,-13.66,;6.05,-12.22,;5.17,-10.99,;4.02,-9.97,;4.94,-8.74,;2.66,-9.18,;3.27,-7.81,;4.85,-7.63,;5.91,-8.75,;7.34,-8.13,;7.14,-6.6,;5.6,-6.32,;1.15,-8.75,;-.43,-8.64,;-.49,-7.1,;-1.97,-8.86,;-2.39,-7.39,;-1.28,-6.32,;-1.67,-4.85,;-.57,-3.77,;-.99,-2.3,;-2.49,-1.91,;.16,-1.25,;-3.44,-9.42,;-4.75,-10.28,;-5.75,-9.11,;-5.8,-11.39,;-6.59,-12.69,;-7.04,-14.15,;-7.19,-15.66,;-6.95,-17.15,;-6.36,-18.59,;-5.48,-19.84,;-6.66,-20.82,;-4.33,-20.86,;-5.25,-22.07,;-6.83,-21.89,;-7.76,-23.14,;-9.31,-22.96,;-10.27,-24.17,;-2.97,-21.63,;-1.46,-22.07,;-1.74,-23.57,;.11,-22.18,;.18,-23.71,;-1.17,-24.51,;1.65,-21.95,;3.13,-21.39,;3.84,-22.74,;4.42,-20.56,;5.49,-19.42,;6.28,-18.12,;6.75,-16.67,;8.27,-16.95,;6.85,-15.15,;5.46,-21.7,;6.98,-21.42,;7.52,-19.96,;8.03,-22.57,;9.56,-22.29,;7.5,-24,;8.5,-25.15,;10,-24.87,;11.01,-26.01,;10.49,-27.45,;11.47,-28.63,;8.97,-27.73,;7.99,-26.57,;10.89,-11.76,;12.25,-11.01,;9.54,-10.97,;9.54,-9.45,;24.4,-13.59,;24.4,-12.07,;25.75,-14.37,;27.09,-13.66,;27.12,-12.12,;25.76,-11.33,;28.47,-11.4,;28.44,-14.45,;28.44,-15.97,;29.81,-13.69,;31.13,-14.52,;31.13,-16.01,;32.5,-16.81,;32.5,-18.35,;33.82,-19.12,;33.82,-20.64,;35.17,-21.43,;32.46,-21.38,;32.52,-13.76,;32.52,-12.25,;33.86,-14.55,;35.22,-13.82,;35.22,-12.32,;36.57,-11.58,;36.58,-10.08,;35.25,-9.28,;37.96,-9.35,;36.54,-14.62,;36.53,-16.16,;37.93,-13.91,;39.26,-14.7,;39.26,-16.22,;40.59,-16.99,;40.59,-18.52,;41.91,-19.32,;41.91,-20.86,;43.28,-21.63,;40.59,-21.57,;40.63,-13.97,;40.63,-12.44,;41.95,-14.76,;43.31,-14.04,;43.31,-12.5,;44.67,-11.78,;46.03,-12.58,;47.38,-11.83,;47.39,-10.31,;48.74,-9.57,;46.06,-9.53,;44.7,-10.25,;44.66,-14.8,;46.02,-14.09,;44.66,-16.34,)| Show InChI InChI=1S/C96H156N32O25/c1-8-50(5)75(127-88(147)69-46-112-80(139)66(43-55-45-107-48-113-55)122-81(140)60(19-15-37-109-94(101)102)114-73(135)22-11-10-14-36-108-79(138)59(18-12-13-35-97)117-89(148)70(47-129)125-85(144)64(32-34-74(136)115-69)116-78(137)58(98)41-53-23-27-56(131)28-24-53)90(149)123-67(44-72(100)134)86(145)121-65(40-49(3)4)87(146)126-76(51(6)9-2)91(150)128-77(52(7)130)92(151)120-62(21-17-39-111-96(105)106)82(141)119-63(31-33-71(99)133)84(143)118-61(20-16-38-110-95(103)104)83(142)124-68(93(152)153)42-54-25-29-57(132)30-26-54/h23-30,45,48-52,58-70,75-77,129-132H,8-22,31-44,46-47,97-98H2,1-7H3,(H2,99,133)(H2,100,134)(H,107,113)(H,108,138)(H,112,139)(H,114,135)(H,115,136)(H,116,137)(H,117,148)(H,118,143)(H,119,141)(H,120,151)(H,121,145)(H,122,140)(H,123,149)(H,124,142)(H,125,144)(H,126,146)(H,127,147)(H,128,150)(H,152,153)(H4,101,102,109)(H4,103,104,110)(H4,105,106,111)/t50-,51-,52+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046557
(CHEMBL2370624 | Tyr-c(Glu-Ser-Lys-(Aca)-Arg-His-(D...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CNC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |wU:103.105,28.27,24.24,8.12,141.143,33.33,121.123,86.88,71.72,104.108,43.44,62.63,2.2,wD:4.4,16.20,77.84,110.112,130.132,96.99,(21.68,-18.1,;21.68,-16.56,;23.04,-15.83,;24.37,-16.63,;23.04,-14.3,;21.7,-13.51,;20.32,-14.27,;20.34,-15.77,;18.99,-13.47,;18.99,-11.94,;20.35,-11.22,;20.38,-9.68,;21.72,-12.01,;17.63,-14.19,;16.3,-13.41,;16.3,-11.89,;14.93,-14.12,;14.91,-15.66,;16.27,-16.45,;17.62,-15.72,;16.26,-17.95,;13.59,-13.33,;12.22,-14.07,;12.21,-15.59,;10.9,-13.29,;9.25,-14.34,;8.14,-13.26,;8.54,-11.79,;6.64,-13.66,;6.05,-12.22,;5.17,-10.99,;4.02,-9.97,;4.94,-8.74,;2.66,-9.18,;3.27,-7.81,;4.85,-7.63,;5.91,-8.75,;7.34,-8.13,;7.14,-6.6,;5.6,-6.32,;1.15,-8.75,;-.43,-8.64,;-.49,-7.1,;-1.97,-8.86,;-2.39,-7.39,;-1.28,-6.32,;-1.67,-4.85,;-.57,-3.77,;-.99,-2.3,;-2.49,-1.91,;.16,-1.25,;-3.44,-9.42,;-4.75,-10.28,;-5.75,-9.11,;-5.8,-11.39,;-6.59,-12.69,;-7.04,-14.15,;-7.19,-15.66,;-6.95,-17.15,;-6.36,-18.59,;-5.48,-19.84,;-6.66,-20.82,;-4.33,-20.86,;-5.25,-22.07,;-6.83,-21.89,;-7.76,-23.14,;-9.31,-22.96,;-10.27,-24.17,;-2.97,-21.63,;-1.46,-22.07,;-1.74,-23.57,;.11,-22.18,;.18,-23.71,;-1.17,-24.51,;1.65,-21.95,;3.13,-21.39,;3.84,-22.74,;4.42,-20.56,;5.49,-19.42,;6.28,-18.12,;6.75,-16.67,;8.27,-16.95,;6.85,-15.15,;5.46,-21.7,;6.98,-21.42,;7.52,-19.96,;8.03,-22.57,;9.56,-22.29,;7.5,-24,;8.5,-25.15,;10,-24.87,;11.01,-26.01,;10.49,-27.45,;11.47,-28.63,;8.97,-27.73,;7.99,-26.57,;10.89,-11.76,;12.25,-11.01,;9.54,-10.97,;9.54,-9.45,;24.4,-13.59,;24.4,-12.07,;25.75,-14.37,;27.09,-13.66,;27.12,-12.12,;25.76,-11.33,;28.47,-11.4,;28.44,-14.45,;28.44,-15.97,;29.81,-13.69,;31.13,-14.52,;31.13,-16.01,;32.5,-16.81,;32.5,-18.35,;33.82,-19.12,;33.82,-20.64,;35.17,-21.43,;32.46,-21.38,;32.52,-13.76,;32.52,-12.25,;33.86,-14.55,;35.22,-13.82,;35.22,-12.32,;36.57,-11.58,;36.58,-10.08,;35.25,-9.28,;37.96,-9.35,;36.54,-14.62,;36.53,-16.16,;37.93,-13.91,;39.26,-14.7,;39.26,-16.22,;40.59,-16.99,;40.59,-18.52,;41.91,-19.32,;41.91,-20.86,;43.28,-21.63,;40.59,-21.57,;40.63,-13.97,;40.63,-12.44,;41.95,-14.76,;43.31,-14.04,;43.31,-12.5,;44.67,-11.78,;46.03,-12.58,;47.38,-11.83,;47.39,-10.31,;48.74,-9.57,;46.06,-9.53,;44.7,-10.25,;44.66,-14.8,;46.02,-14.09,;44.66,-16.34,)| Show InChI InChI=1S/C96H156N32O25/c1-8-50(5)75(127-88(147)69-46-112-80(139)66(43-55-45-107-48-113-55)122-81(140)60(19-15-37-109-94(101)102)114-73(135)22-11-10-14-36-108-79(138)59(18-12-13-35-97)117-89(148)70(47-129)125-85(144)64(32-34-74(136)115-69)116-78(137)58(98)41-53-23-27-56(131)28-24-53)90(149)123-67(44-72(100)134)86(145)121-65(40-49(3)4)87(146)126-76(51(6)9-2)91(150)128-77(52(7)130)92(151)120-62(21-17-39-111-96(105)106)82(141)119-63(31-33-71(99)133)84(143)118-61(20-16-38-110-95(103)104)83(142)124-68(93(152)153)42-54-25-29-57(132)30-26-54/h23-30,45,48-52,58-70,75-77,129-132H,8-22,31-44,46-47,97-98H2,1-7H3,(H2,99,133)(H2,100,134)(H,107,113)(H,108,138)(H,112,139)(H,114,135)(H,115,136)(H,116,137)(H,117,148)(H,118,143)(H,119,141)(H,120,151)(H,121,145)(H,122,140)(H,123,149)(H,124,142)(H,125,144)(H,126,146)(H,127,147)(H,128,150)(H,152,153)(H4,101,102,109)(H4,103,104,110)(H4,105,106,111)/t50-,51-,52+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50046548
(CHEMBL2370634 | Tyr-c(Asp-Ser-Lys-Pro-(D-Ala)-Arg-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:95.97,63.65,23.148,79.81,133.135,113.115,96.100,55.57,88.91,1.0,wD:29.62,87.89,71.73,34.35,102.104,122.124,148.152,17.18,8.9,44.46,64.67,(-9.58,-18.14,;-8.43,-16.67,;-9.98,-16.93,;-10.74,-15.55,;-9.65,-14.46,;-8.23,-15.15,;-7.65,-13.72,;-9.06,-12.97,;-6.76,-12.47,;-7.94,-11.42,;-9.46,-11.92,;-10.64,-10.86,;-12.13,-11.35,;-13.29,-10.3,;-5.6,-11.46,;-4.22,-10.73,;-4.82,-9.3,;-2.7,-10.33,;-2.94,-8.82,;-4.41,-8.22,;-1.12,-10.3,;.41,-10.63,;.89,-9.17,;1.85,-11.29,;3.08,-12.25,;4.07,-13.49,;4.75,-14.89,;6.24,-14.41,;5.08,-16.39,;5.05,-17.94,;4.65,-19.41,;3.9,-20.78,;2.88,-21.91,;3.94,-23.09,;1.59,-22.79,;2.35,-24.15,;3.93,-24.22,;4.88,-22.99,;6.37,-23.53,;6.33,-25.08,;4.83,-25.5,;.14,-23.35,;-1.42,-23.56,;-1.35,-25.11,;-2.99,-23.42,;-3.29,-24.91,;-2.1,-25.96,;-2.41,-27.45,;-1.22,-28.5,;-1.54,-30.01,;-3.02,-30.49,;-.35,-31.05,;-4.49,-22.92,;-5.83,-22.1,;-6.79,-23.3,;-6.96,-20.99,;-8.17,-21.94,;-7.81,-19.69,;-8.3,-18.22,;-9.83,-18.51,;6.61,-18.17,;7.29,-16.83,;7.8,-19.31,;9.2,-18.78,;9.47,-17.25,;10.86,-16.72,;8.34,-16.24,;8.59,-14.72,;10.33,-19.77,;10.06,-21.31,;11.72,-19.24,;12.84,-20.23,;12.58,-21.78,;13.7,-22.77,;15.12,-22.24,;13.44,-24.31,;14.25,-19.7,;14.51,-18.17,;15.38,-20.71,;16.77,-20.16,;17.03,-18.65,;18.42,-18.12,;18.7,-16.57,;19.54,-19.1,;17.89,-21.15,;17.62,-22.7,;19.3,-20.63,;20.43,-21.64,;20.15,-23.17,;21.29,-24.15,;18.75,-23.71,;18.48,-25.23,;21.81,-21.09,;22.1,-19.57,;22.93,-22.1,;24.35,-21.55,;24.61,-20.03,;23.48,-19.01,;25.99,-19.5,;25.47,-22.56,;25.2,-24.09,;26.86,-22.03,;28,-23.02,;27.72,-24.55,;28.84,-25.54,;28.57,-27.09,;29.72,-28.08,;29.45,-29.62,;30.59,-30.62,;28.05,-30.16,;29.39,-22.49,;29.66,-20.96,;30.52,-23.48,;31.91,-22.96,;32.17,-21.42,;33.58,-20.89,;33.85,-19.34,;32.72,-18.35,;35.24,-18.81,;33.05,-23.96,;32.79,-25.47,;34.45,-23.42,;35.57,-24.42,;35.3,-25.94,;36.41,-26.98,;36.16,-28.48,;37.28,-29.49,;37.02,-31.02,;38.16,-32,;35.63,-31.54,;36.95,-23.89,;37.24,-22.34,;38.1,-24.88,;39.49,-24.35,;39.76,-22.8,;41.14,-22.27,;42.28,-23.26,;43.68,-22.74,;43.94,-21.21,;45.35,-20.66,;42.81,-20.22,;41.4,-20.76,;40.61,-25.34,;42.02,-24.81,;40.35,-26.88,;2.67,-9.99,;4.23,-10.06,;4.99,-11.39,;5.05,-8.75,;6.61,-8.81,;4.29,-7.37,;4.35,-5.85,;5.18,-4.55,;4.42,-3.18,;2.81,-3.13,;2.29,-1.73,;2.01,-4.43,;2.77,-5.8,)| Show InChI InChI=1S/C98H157N33O26/c1-9-49(5)75(91(152)125-67(43-73(102)137)86(147)123-65(39-48(3)4)87(148)128-76(50(6)10-2)92(153)130-77(52(8)133)93(154)121-61(20-15-37-112-98(107)108)81(142)120-62(30-32-72(101)136)84(145)119-60(19-14-36-111-97(105)106)83(144)126-68(95(156)157)41-54-24-28-57(135)29-25-54)129-88(149)69-45-113-80(141)66(42-55-44-109-47-114-55)124-82(143)59(18-13-35-110-96(103)104)117-78(139)51(7)115-90(151)71-21-16-38-131(71)94(155)64(17-11-12-34-99)122-89(150)70(46-132)127-85(146)63(31-33-74(138)116-69)118-79(140)58(100)40-53-22-26-56(134)27-23-53/h22-29,44,47-52,58-71,75-77,132-135H,9-21,30-43,45-46,99-100H2,1-8H3,(H2,101,136)(H2,102,137)(H,109,114)(H,113,141)(H,115,151)(H,116,138)(H,117,139)(H,118,140)(H,119,145)(H,120,142)(H,121,154)(H,122,150)(H,123,147)(H,124,143)(H,125,152)(H,126,144)(H,127,146)(H,128,148)(H,129,149)(H,130,153)(H,156,157)(H4,103,104,110)(H4,105,106,111)(H4,107,108,112)/t49-,50-,51+,52+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046543
(CHEMBL2370632 | Tyr-c((D-Glu)-Ser-Lys-Pro-(D-Ala)-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:28.61,86.88,70.72,33.34,101.103,121.123,147.151,17.18,8.9,43.45,63.66,wD:94.96,23.147,62.64,78.80,132.134,112.114,95.99,54.56,87.90,1.0,(-7.53,-.27,;-7.57,-2.13,;-8.61,-.98,;-10.04,-1.58,;-9.92,-3.08,;-8.39,-3.44,;-8.85,-4.89,;-10.39,-4.59,;-8.94,-6.4,;-10.5,-6.51,;-11.36,-5.23,;-12.91,-5.31,;-13.77,-4.04,;-15.32,-4.13,;-8.66,-7.9,;-8.01,-9.27,;-9.35,-10.06,;-7.05,-10.48,;-8.15,-11.54,;-9.66,-11.17,;-5.82,-11.41,;-4.4,-12.03,;-4.88,-13.5,;-2.86,-12.3,;-1.31,-12.22,;.18,-11.77,;.83,-13.13,;1.53,-10.98,;2.62,-9.92,;3.42,-8.61,;3.87,-7.16,;3.97,-5.65,;5.52,-5.55,;3.68,-4.14,;5.18,-3.7,;6.31,-4.73,;6.14,-6.24,;7.55,-6.86,;8.62,-5.75,;7.85,-4.42,;3.04,-2.75,;2.08,-1.56,;3.17,-.49,;.84,-.63,;1.66,.65,;3.2,.64,;4.03,1.92,;5.58,1.89,;6.38,3.2,;7.93,3.19,;5.62,4.53,;-.57,-.01,;-2.12,.26,;-2.02,1.78,;-3.67,.16,;-3.95,1.68,;-5.15,-.25,;-6.5,-1.04,;-7.44,.14,;3.86,-10.84,;3.63,-12.34,;5.3,-10.27,;6.52,-11.2,;6.3,-12.72,;7.54,-13.64,;4.87,-13.29,;4.65,-14.78,;7.96,-10.65,;8.17,-9.16,;9.2,-11.6,;10.64,-11.02,;10.86,-9.51,;12.3,-8.95,;13.53,-9.89,;12.51,-7.45,;11.88,-11.96,;11.65,-13.46,;13.32,-11.37,;14.54,-12.34,;14.33,-13.84,;15.56,-14.77,;17.02,-14.2,;15.33,-16.26,;15.99,-11.77,;16.19,-10.26,;17.23,-12.7,;18.66,-12.13,;18.88,-10.62,;20.32,-10.06,;17.64,-9.69,;17.84,-8.19,;19.88,-13.08,;19.67,-14.57,;21.32,-12.51,;22.56,-13.43,;22.36,-14.95,;20.91,-15.5,;23.58,-15.88,;24.01,-12.88,;24.21,-11.37,;25.24,-13.81,;26.68,-13.25,;26.9,-11.72,;28.35,-11.17,;28.57,-9.69,;30,-9.1,;30.23,-7.59,;31.67,-7.03,;28.97,-6.66,;27.9,-14.18,;27.69,-15.68,;29.34,-13.61,;30.58,-14.54,;30.38,-16.05,;31.6,-16.98,;31.38,-18.5,;29.95,-19.07,;32.61,-19.45,;32.03,-13.99,;32.24,-12.47,;33.26,-14.92,;34.71,-14.37,;34.92,-12.85,;36.37,-12.27,;36.6,-10.78,;38.02,-10.23,;38.25,-8.71,;39.69,-8.14,;37.02,-7.76,;35.92,-15.3,;35.71,-16.8,;37.39,-14.73,;38.6,-15.68,;38.4,-17.16,;39.63,-18.11,;39.4,-19.6,;40.64,-20.53,;42.08,-19.98,;43.31,-20.91,;42.29,-18.46,;41.07,-17.54,;40.05,-15.11,;41.28,-16.04,;40.26,-13.6,;-2.95,-13.82,;-1.64,-14.67,;-.26,-13.99,;-1.74,-16.18,;-.44,-17.02,;-3.13,-16.85,;-3.99,-18.19,;-5.57,-18.25,;-6.36,-19.53,;-5.61,-20.79,;-6.43,-22.07,;-4.06,-20.74,;-3.24,-19.52,)| Show InChI InChI=1S/C97H155N33O26/c1-9-48(5)74(90(151)124-65(41-72(101)136)84(145)122-63(37-47(3)4)86(147)127-75(49(6)10-2)91(152)129-76(51(8)132)92(153)119-60(20-15-35-111-97(106)107)80(141)118-61(30-31-71(100)135)83(144)117-59(19-14-34-110-96(104)105)82(143)125-67(94(155)156)39-53-24-28-56(134)29-25-53)128-87(148)68-44-112-79(140)64(40-54-43-108-46-113-54)123-81(142)58(18-13-33-109-95(102)103)116-77(138)50(7)114-89(150)70-21-16-36-130(70)93(154)62(17-11-12-32-98)120-88(149)69(45-131)126-85(146)66(42-73(137)115-68)121-78(139)57(99)38-52-22-26-55(133)27-23-52/h22-29,43,46-51,57-70,74-76,131-134H,9-21,30-42,44-45,98-99H2,1-8H3,(H2,100,135)(H2,101,136)(H,108,113)(H,112,140)(H,114,150)(H,115,137)(H,116,138)(H,117,144)(H,118,141)(H,119,153)(H,120,149)(H,121,139)(H,122,145)(H,123,142)(H,124,151)(H,125,143)(H,126,146)(H,127,147)(H,128,148)(H,129,152)(H,155,156)(H4,102,103,109)(H4,104,105,110)(H4,106,107,111)/t48-,49-,50+,51+,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,74-,75-,76-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046550
(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C102H161N31O25/c1-8-55(5)81(95(153)127-74(50-79(106)140)90(148)124-71(45-54(3)4)91(149)131-82(56(6)9-2)96(154)132-83(57(7)135)97(155)123-69(22-17-43-117-102(111)112)86(144)122-70(37-38-78(105)139)88(146)121-68(21-16-42-116-101(109)110)87(145)128-75(99(157)158)48-60-29-35-64(138)36-30-60)130-92(150)72(47-59-27-33-63(137)34-28-59)125-89(147)73(49-61-51-113-53-118-61)126-85(143)67(20-15-41-115-100(107)108)119-80(141)24-11-10-14-40-114-84(142)66(19-12-13-39-103)120-93(151)76(52-134)129-94(152)77-23-18-44-133(77)98(156)65(104)46-58-25-31-62(136)32-26-58/h25-36,51,53-57,65-77,81-83,134-138H,8-24,37-50,52,103-104H2,1-7H3,(H2,105,139)(H2,106,140)(H,113,118)(H,114,142)(H,119,141)(H,120,151)(H,121,146)(H,122,144)(H,123,155)(H,124,148)(H,125,147)(H,126,143)(H,127,153)(H,128,145)(H,129,152)(H,130,150)(H,131,149)(H,132,154)(H,157,158)(H4,107,108,115)(H4,109,110,116)(H4,111,112,117)/t55-,56-,57+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 261 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046546
(CHEMBL414051 | Tyr-Pro-Ser-Lys-Pro-(D-Ala)-Arg-His...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C104H162N32O26/c1-9-54(5)81(96(156)129-74(49-80(108)143)90(150)126-71(44-53(3)4)91(151)133-82(55(6)10-2)97(157)134-83(57(8)138)98(158)124-68(21-15-41-118-104(113)114)85(145)123-69(36-37-79(107)142)88(148)122-67(20-14-40-117-103(111)112)87(147)130-75(101(161)162)47-60-28-34-64(141)35-29-60)132-92(152)72(46-59-26-32-63(140)33-27-59)127-89(149)73(48-61-50-115-52-119-61)128-86(146)66(19-13-39-116-102(109)110)121-84(144)56(7)120-94(154)77-22-17-43-136(77)100(160)70(18-11-12-38-105)125-93(153)76(51-137)131-95(155)78-23-16-42-135(78)99(159)65(106)45-58-24-30-62(139)31-25-58/h24-35,50,52-57,65-78,81-83,137-141H,9-23,36-49,51,105-106H2,1-8H3,(H2,107,142)(H2,108,143)(H,115,119)(H,120,154)(H,121,144)(H,122,148)(H,123,145)(H,124,158)(H,125,153)(H,126,150)(H,127,149)(H,128,146)(H,129,156)(H,130,147)(H,131,155)(H,132,152)(H,133,151)(H,134,157)(H,161,162)(H4,109,110,116)(H4,111,112,117)(H4,113,114,118)/t54-,55-,56+,57+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,81-,82-,83-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046549
(CHEMBL410007 | Tyr-Pro-Ser-Lys-c(Glu-Asp-Asn-Pro-(...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N2CCC[C@@H]2C(=O)N[C@H](C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@H](C)C(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C153H230N46O42/c1-10-77(5)120(144(235)190-107(69-116(157)209)136(227)184-102(62-76(3)4)138(229)196-121(78(6)11-2)145(236)197-122(81(9)202)146(237)183-99(27-19-59-172-153(165)166)127(218)181-100(50-52-115(156)208)131(222)179-98(26-18-58-171-152(163)164)130(221)192-110(149(240)241)67-86-38-48-92(207)49-39-86)195-139(230)105(66-85-36-46-91(206)47-37-85)187-135(226)106(68-87-72-167-75-173-87)188-129(220)97(25-17-57-170-151(161)162)178-125(216)94-23-13-15-55-168-118(211)53-51-101(182-126(217)95(22-12-14-54-154)180-141(232)112(74-201)194-143(234)114-29-20-60-198(114)147(238)93(155)63-82-30-40-88(203)41-31-82)132(223)189-108(71-119(212)213)137(228)191-109(70-117(158)210)148(239)199-61-21-28-113(199)142(233)175-80(8)124(215)177-96(24-16-56-169-150(159)160)128(219)185-103(64-83-32-42-89(204)43-33-83)133(224)186-104(65-84-34-44-90(205)45-35-84)134(225)193-111(73-200)140(231)174-79(7)123(214)176-94/h30-49,72,75-81,93-114,120-122,200-207H,10-29,50-71,73-74,154-155H2,1-9H3,(H2,156,208)(H2,157,209)(H2,158,210)(H,167,173)(H,168,211)(H,174,231)(H,175,233)(H,176,214)(H,177,215)(H,178,216)(H,179,222)(H,180,232)(H,181,218)(H,182,217)(H,183,237)(H,184,227)(H,185,219)(H,186,224)(H,187,226)(H,188,220)(H,189,223)(H,190,235)(H,191,228)(H,192,221)(H,193,225)(H,194,234)(H,195,230)(H,196,229)(H,197,236)(H,212,213)(H,240,241)(H4,159,160,169)(H4,161,162,170)(H4,163,164,171)(H4,165,166,172)/t77-,78-,79+,80+,81+,93-,94-,95-,96+,97-,98-,99-,100-,101+,102-,103-,104+,105-,106-,107-,108+,109-,110-,111-,112+,113+,114+,120-,121-,122-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50034125
(CHEMBL265849 | Neuropeptide Y(NPY)(13-36) | Pro-Al...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C135H208N40O37/c1-15-68(9)105(128(208)170-97(60-102(137)183)123(203)164-92(54-67(7)8)125(205)174-106(69(10)16-2)129(209)175-107(73(14)177)130(210)161-87(26-21-51-151-135(144)145)112(192)160-88(43-45-101(136)182)116(196)158-86(25-20-50-150-134(142)143)115(195)171-99(131(211)212)58-77-33-41-82(181)42-34-77)173-126(206)95(57-76-31-39-81(180)40-32-76)167-122(202)96(59-78-62-146-64-152-78)168-114(194)85(24-19-49-149-133(140)141)159-119(199)91(53-66(5)6)162-110(190)72(13)155-127(207)100(63-176)172-121(201)94(56-75-29-37-80(179)38-30-75)166-120(200)93(55-74-27-35-79(178)36-28-74)165-113(193)84(23-18-48-148-132(138)139)156-108(188)71(12)154-118(198)90(52-65(3)4)163-124(204)98(61-104(186)187)169-117(197)89(44-46-103(184)185)157-109(189)70(11)153-111(191)83-22-17-47-147-83/h27-42,62,64-73,83-100,105-107,147,176-181H,15-26,43-61,63H2,1-14H3,(H2,136,182)(H2,137,183)(H,146,152)(H,153,191)(H,154,198)(H,155,207)(H,156,188)(H,157,189)(H,158,196)(H,159,199)(H,160,192)(H,161,210)(H,162,190)(H,163,204)(H,164,203)(H,165,193)(H,166,200)(H,167,202)(H,168,194)(H,169,197)(H,170,208)(H,171,195)(H,172,201)(H,173,206)(H,174,205)(H,175,209)(H,184,185)(H,186,187)(H,211,212)(H4,138,139,148)(H4,140,141,149)(H4,142,143,150)(H4,144,145,151)/t68-,69-,70-,71-,72-,73+,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,105-,106-,107-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046552
(CHEMBL2370635 | Tyr-c(Glu-Ser-Lys-Pro-(D-Ala)-Arg-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@]([H])(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)CC)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:29.62,90.93,34.35,105.108,125.128,82.85,151.156,17.18,8.9,44.46,wD:73.105,23.152,136.139,63.65,116.119,55.57,98.102,77.80,1.0,(-1.39,-13.1,;-.48,-14.73,;-1.94,-14.26,;-2.86,-15.49,;-1.94,-16.74,;-.48,-16.27,;-.12,-17.75,;-1.57,-18.28,;.57,-19.12,;-.71,-19.97,;-2.1,-19.28,;-3.39,-20.11,;-4.77,-19.44,;-6.06,-20.27,;1.56,-20.31,;2.81,-21.22,;2.02,-22.54,;4.22,-21.83,;3.77,-23.3,;2.28,-23.64,;5.74,-22.09,;7.27,-21.99,;7.56,-23.51,;8.76,-21.56,;10.11,-20.79,;11.23,-19.75,;12.08,-18.46,;13.44,-19.15,;12.61,-17.01,;12.78,-15.49,;12.61,-13.97,;12.08,-12.52,;11.23,-11.23,;12.41,-10.26,;10.11,-10.2,;11.03,-8.95,;12.55,-9.14,;13.31,-10.47,;14.83,-10.18,;15.02,-8.66,;13.61,-8.02,;8.76,-9.44,;7.27,-8.99,;7.56,-7.47,;5.74,-8.91,;5.65,-7.37,;6.94,-6.51,;6.86,-4.99,;8.15,-4.16,;8.06,-2.62,;9.35,-1.78,;6.68,-1.93,;4.22,-9.17,;2.81,-9.78,;2.02,-8.45,;1.56,-10.69,;.51,-9.57,;.57,-11.86,;-.12,-13.23,;-1.57,-12.72,;14.32,-15.49,;15.09,-16.81,;15.09,-14.17,;16.64,-14.17,;16.88,-15.69,;17.53,-17.06,;18.59,-18.18,;19.93,-18.95,;21.43,-19.31,;22.98,-19.19,;23.31,-20.67,;24.42,-18.62,;25.62,-17.67,;26.48,-16.4,;26.94,-14.93,;26.94,-13.4,;28.48,-13.18,;26.48,-11.92,;26.97,-10.12,;25.62,-10.67,;24.42,-9.71,;25.19,-8.38,;22.98,-9.15,;23.31,-7.66,;24.62,-6.58,;25.52,-7,;25.15,-5.71,;21.43,-9.04,;19.93,-9.38,;19.37,-7.95,;18.59,-10.14,;17.63,-8.94,;17.6,-7.49,;18.92,-6.74,;16.38,-6.74,;17.53,-11.26,;16.88,-12.65,;15.39,-12.19,;27.89,-11.26,;29.15,-12.12,;28,-9.74,;29.38,-9.08,;27.89,-17.06,;29.15,-16.2,;28,-18.59,;29.38,-19.25,;30.67,-18.39,;32.06,-19.05,;33.34,-18.19,;34.73,-18.86,;36,-18,;37.4,-18.66,;35.88,-16.47,;29.51,-20.79,;28.23,-21.66,;30.9,-21.46,;31.02,-22.98,;29.75,-23.84,;29.84,-25.38,;28.58,-26.25,;27.17,-25.58,;28.69,-27.77,;32.41,-23.64,;33.67,-22.78,;32.52,-25.18,;33.9,-25.84,;35.19,-24.98,;36.58,-25.65,;37.86,-24.78,;39.25,-25.46,;40.53,-24.59,;41.92,-25.25,;40.41,-23.05,;34.04,-27.37,;32.75,-28.23,;35.42,-28.03,;35.54,-29.57,;34.26,-30.44,;34.37,-31.96,;33.1,-32.81,;33.21,-34.35,;34.6,-35.03,;34.73,-36.54,;35.88,-34.16,;35.77,-32.62,;36.93,-30.24,;37.04,-31.76,;38.19,-29.37,;9.37,-22.97,;10.9,-23.15,;11.83,-21.92,;11.53,-24.55,;13.05,-24.73,;10.6,-25.79,;10.34,-27.14,;9.05,-26.37,;7.67,-27.07,;7.6,-28.56,;6.25,-29.24,;8.91,-29.31,;10.27,-28.61,)| Show InChI InChI=1S/C99H156N34O26/c1-6-51(4)78-94(156)125-65(87(149)121-61(18-12-38-113-98(106)107)82(144)124-63(29-32-74(102)137)86(148)122-62(19-13-39-114-99(108)109)85(147)130-70(96(158)159)43-54-23-27-57(136)28-24-54)30-33-76(139)111-36-10-8-15-59(83(145)129-69(45-75(103)138)89(151)127-67(41-50(2)3)90(152)132-78)123-91(153)71-47-115-81(143)68(44-55-46-110-49-116-55)128-84(146)60(17-11-37-112-97(104)105)119-79(141)52(5)117-93(155)73-20-14-40-133(73)95(157)66(16-7-9-35-100)126-92(154)72(48-134)131-88(150)64(31-34-77(140)118-71)120-80(142)58(101)42-53-21-25-56(135)26-22-53/h21-28,46,49-52,58-73,78,134-136H,6-20,29-45,47-48,100-101H2,1-5H3,(H2,102,137)(H2,103,138)(H,110,116)(H,111,139)(H,115,143)(H,117,155)(H,118,140)(H,119,141)(H,120,142)(H,121,149)(H,122,148)(H,123,153)(H,124,144)(H,125,156)(H,126,154)(H,127,151)(H,128,146)(H,129,145)(H,130,147)(H,131,150)(H,132,152)(H,158,159)(H4,104,105,112)(H4,106,107,113)(H4,108,109,114)/t51-,52+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,78-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046559
(CHEMBL427974 | Tyr-c(Asp-Ser-Lys-Pro-(D-Ala)-Arg-H...)Show SMILES CC[C@@H](C)[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](NC(=O)[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@H](CCCCN)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2cnc[nH]2)C(=O)N1)[C@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C100H161N33O26/c1-9-51(5)77(93(154)127-69(45-75(104)139)88(149)125-67(41-50(3)4)90(151)131-78(52(6)10-2)94(155)132-79(54(8)135)95(156)122-64(23-17-39-115-100(109)110)82(143)121-65(33-34-74(103)138)85(146)119-63(22-16-38-114-99(107)108)84(145)128-71(97(158)159)43-56-27-31-59(137)32-28-56)130-86(147)61-19-12-14-36-112-76(140)46-70(124-81(142)60(102)42-55-25-29-58(136)30-26-55)89(150)129-72(48-134)91(152)123-66(20-11-13-35-101)96(157)133-40-18-24-73(133)92(153)117-53(7)80(141)118-62(21-15-37-113-98(105)106)83(144)126-68(87(148)120-61)44-57-47-111-49-116-57/h25-32,47,49-54,60-73,77-79,134-137H,9-24,33-46,48,101-102H2,1-8H3,(H2,103,138)(H2,104,139)(H,111,116)(H,112,140)(H,117,153)(H,118,141)(H,119,146)(H,120,148)(H,121,143)(H,122,156)(H,123,152)(H,124,142)(H,125,149)(H,126,144)(H,127,154)(H,128,145)(H,129,150)(H,130,147)(H,131,151)(H,132,155)(H,158,159)(H4,105,106,113)(H4,107,108,114)(H4,109,110,115)/t51-,52-,53+,54+,60+,61+,62+,63-,64-,65-,66-,67-,68-,69-,70+,71-,72+,73+,77-,78-,79-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046548
(CHEMBL2370634 | Tyr-c(Asp-Ser-Lys-Pro-(D-Ala)-Arg-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](C)NC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:95.97,63.65,23.148,79.81,133.135,113.115,96.100,55.57,88.91,1.0,wD:29.62,87.89,71.73,34.35,102.104,122.124,148.152,17.18,8.9,44.46,64.67,(-9.58,-18.14,;-8.43,-16.67,;-9.98,-16.93,;-10.74,-15.55,;-9.65,-14.46,;-8.23,-15.15,;-7.65,-13.72,;-9.06,-12.97,;-6.76,-12.47,;-7.94,-11.42,;-9.46,-11.92,;-10.64,-10.86,;-12.13,-11.35,;-13.29,-10.3,;-5.6,-11.46,;-4.22,-10.73,;-4.82,-9.3,;-2.7,-10.33,;-2.94,-8.82,;-4.41,-8.22,;-1.12,-10.3,;.41,-10.63,;.89,-9.17,;1.85,-11.29,;3.08,-12.25,;4.07,-13.49,;4.75,-14.89,;6.24,-14.41,;5.08,-16.39,;5.05,-17.94,;4.65,-19.41,;3.9,-20.78,;2.88,-21.91,;3.94,-23.09,;1.59,-22.79,;2.35,-24.15,;3.93,-24.22,;4.88,-22.99,;6.37,-23.53,;6.33,-25.08,;4.83,-25.5,;.14,-23.35,;-1.42,-23.56,;-1.35,-25.11,;-2.99,-23.42,;-3.29,-24.91,;-2.1,-25.96,;-2.41,-27.45,;-1.22,-28.5,;-1.54,-30.01,;-3.02,-30.49,;-.35,-31.05,;-4.49,-22.92,;-5.83,-22.1,;-6.79,-23.3,;-6.96,-20.99,;-8.17,-21.94,;-7.81,-19.69,;-8.3,-18.22,;-9.83,-18.51,;6.61,-18.17,;7.29,-16.83,;7.8,-19.31,;9.2,-18.78,;9.47,-17.25,;10.86,-16.72,;8.34,-16.24,;8.59,-14.72,;10.33,-19.77,;10.06,-21.31,;11.72,-19.24,;12.84,-20.23,;12.58,-21.78,;13.7,-22.77,;15.12,-22.24,;13.44,-24.31,;14.25,-19.7,;14.51,-18.17,;15.38,-20.71,;16.77,-20.16,;17.03,-18.65,;18.42,-18.12,;18.7,-16.57,;19.54,-19.1,;17.89,-21.15,;17.62,-22.7,;19.3,-20.63,;20.43,-21.64,;20.15,-23.17,;21.29,-24.15,;18.75,-23.71,;18.48,-25.23,;21.81,-21.09,;22.1,-19.57,;22.93,-22.1,;24.35,-21.55,;24.61,-20.03,;23.48,-19.01,;25.99,-19.5,;25.47,-22.56,;25.2,-24.09,;26.86,-22.03,;28,-23.02,;27.72,-24.55,;28.84,-25.54,;28.57,-27.09,;29.72,-28.08,;29.45,-29.62,;30.59,-30.62,;28.05,-30.16,;29.39,-22.49,;29.66,-20.96,;30.52,-23.48,;31.91,-22.96,;32.17,-21.42,;33.58,-20.89,;33.85,-19.34,;32.72,-18.35,;35.24,-18.81,;33.05,-23.96,;32.79,-25.47,;34.45,-23.42,;35.57,-24.42,;35.3,-25.94,;36.41,-26.98,;36.16,-28.48,;37.28,-29.49,;37.02,-31.02,;38.16,-32,;35.63,-31.54,;36.95,-23.89,;37.24,-22.34,;38.1,-24.88,;39.49,-24.35,;39.76,-22.8,;41.14,-22.27,;42.28,-23.26,;43.68,-22.74,;43.94,-21.21,;45.35,-20.66,;42.81,-20.22,;41.4,-20.76,;40.61,-25.34,;42.02,-24.81,;40.35,-26.88,;2.67,-9.99,;4.23,-10.06,;4.99,-11.39,;5.05,-8.75,;6.61,-8.81,;4.29,-7.37,;4.35,-5.85,;5.18,-4.55,;4.42,-3.18,;2.81,-3.13,;2.29,-1.73,;2.01,-4.43,;2.77,-5.8,)| Show InChI InChI=1S/C98H157N33O26/c1-9-49(5)75(91(152)125-67(43-73(102)137)86(147)123-65(39-48(3)4)87(148)128-76(50(6)10-2)92(153)130-77(52(8)133)93(154)121-61(20-15-37-112-98(107)108)81(142)120-62(30-32-72(101)136)84(145)119-60(19-14-36-111-97(105)106)83(144)126-68(95(156)157)41-54-24-28-57(135)29-25-54)129-88(149)69-45-113-80(141)66(42-55-44-109-47-114-55)124-82(143)59(18-13-35-110-96(103)104)117-78(139)51(7)115-90(151)71-21-16-38-131(71)94(155)64(17-11-12-34-99)122-89(150)70(46-132)127-85(146)63(31-33-74(138)116-69)118-79(140)58(100)40-53-22-26-56(134)27-23-53/h22-29,44,47-52,58-71,75-77,132-135H,9-21,30-43,45-46,99-100H2,1-8H3,(H2,101,136)(H2,102,137)(H,109,114)(H,113,141)(H,115,151)(H,116,138)(H,117,139)(H,118,140)(H,119,145)(H,120,142)(H,121,154)(H,122,150)(H,123,147)(H,124,143)(H,125,152)(H,126,144)(H,127,146)(H,128,148)(H,129,149)(H,130,153)(H,156,157)(H4,103,104,110)(H4,105,106,111)(H4,107,108,112)/t49-,50-,51+,52+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046556
(CHEMBL2370633 | Tyr-c(Glu-Ser-Lys-Pro-(D-Ala)-Arg-...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N[C@@H](CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC2=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |wU:94.96,29.61,62.64,78.80,132.134,34.35,112.114,147.151,17.18,95.99,8.9,44.46,87.90,wD:86.88,70.72,23.147,101.103,121.123,63.66,1.0,(-3.99,-11.35,;-2.23,-11.99,;-3.67,-12.59,;-3.55,-14.14,;-2.04,-14.49,;-1.22,-13.16,;.03,-14.06,;-.75,-15.42,;1.46,-14.65,;1.02,-16.14,;-.49,-16.53,;-.93,-18.03,;-2.45,-18.41,;-2.89,-19.91,;2.98,-14.89,;4.54,-14.77,;4.82,-16.3,;6.03,-14.29,;6.66,-15.71,;5.73,-16.97,;7.38,-13.5,;8.51,-12.41,;9.7,-13.39,;9.36,-11.09,;9.89,-9.62,;10.05,-8.08,;9.87,-6.55,;11.38,-6.16,;9.33,-5.1,;8.47,-3.82,;7.34,-2.77,;5.98,-2.02,;4.48,-1.61,;4.75,-.08,;2.94,-1.55,;2.84,,;4.14,.88,;5.59,.36,;6.57,1.59,;5.69,2.87,;4.2,2.43,;1.4,-1.84,;-.02,-2.49,;-.8,-1.15,;-1.26,-3.43,;-2.33,-2.32,;-1.89,-.83,;-2.97,.28,;-2.53,1.77,;-3.61,2.88,;-3.16,4.38,;-5.13,2.5,;-2.26,-4.64,;-2.95,-6.05,;-4.42,-5.54,;-3.31,-7.55,;-3.31,-9.11,;-2.93,-10.61,;-4.4,-11.16,;9.66,-2.79,;9.38,-1.28,;11.64,-2.7,;12.82,-2.16,;12.93,-.63,;14.12,-.1,;11.88,.37,;12.01,1.9,;13.87,-3.16,;13.76,-4.69,;15.06,-2.62,;16.11,-3.63,;15.99,-5.16,;16.81,-6.05,;18.4,-6.28,;16.34,-7.55,;17.3,-3.09,;17.42,-1.57,;18.35,-4.09,;19.54,-3.56,;19.66,-2.03,;20.84,-1.49,;21.9,-2.49,;20.97,.04,;20.59,-4.56,;20.47,-6.08,;21.78,-4.03,;22.83,-5.03,;22.71,-6.55,;23.77,-7.55,;21.53,-7.09,;21.4,-8.62,;24.02,-4.5,;24.15,-2.96,;25.07,-5.49,;26.26,-4.96,;26.38,-3.43,;25.33,-2.43,;27.57,-2.9,;27.32,-5.96,;27.2,-7.5,;28.5,-5.43,;29.56,-6.42,;29.44,-7.96,;30.49,-8.96,;30.37,-10.49,;31.43,-11.48,;31.3,-13.02,;32.37,-14.02,;30.13,-13.55,;30.73,-5.9,;30.87,-4.37,;31.8,-6.89,;32.97,-6.36,;33.11,-4.82,;34.29,-4.3,;34.4,-2.77,;33.35,-1.77,;35.59,-2.23,;34.04,-7.36,;33.91,-8.89,;35.23,-6.83,;36.28,-7.83,;36.15,-9.36,;37.21,-10.36,;37.09,-11.89,;38.15,-12.89,;38.03,-14.42,;39.08,-15.42,;36.84,-14.95,;37.46,-7.29,;37.58,-5.76,;38.52,-8.29,;39.7,-7.76,;39.82,-6.22,;41.01,-5.69,;41.13,-4.16,;42.31,-3.64,;43.37,-4.63,;44.55,-4.1,;43.25,-6.16,;42.06,-6.69,;40.76,-8.76,;41.93,-8.23,;40.63,-10.29,;10.75,-11.77,;12.05,-10.88,;11.95,-9.34,;13.44,-11.56,;14.74,-10.68,;13.54,-13.1,;14.8,-14.29,;14.7,-15.85,;15.96,-16.75,;17.33,-16.09,;18.59,-16.98,;17.43,-14.53,;16.17,-13.63,)| Show InChI InChI=1S/C97H155N33O26/c1-8-49(5)75(90(151)124-66(42-72(101)136)85(146)122-64(38-48(3)4)86(147)127-76(50(6)9-2)91(152)129-77(51(7)132)92(153)120-60(19-14-36-111-97(106)107)81(142)119-61(29-31-71(100)135)83(144)118-59(18-13-35-110-96(104)105)82(143)125-67(94(155)156)40-53-23-27-56(134)28-24-53)128-87(148)68-44-112-79(140)65(41-54-43-108-47-114-54)123-80(141)58(17-12-34-109-95(102)103)115-74(138)45-113-89(150)70-20-15-37-130(70)93(154)63(16-10-11-33-98)121-88(149)69(46-131)126-84(145)62(30-32-73(137)116-68)117-78(139)57(99)39-52-21-25-55(133)26-22-52/h21-28,43,47-51,57-70,75-77,131-134H,8-20,29-42,44-46,98-99H2,1-7H3,(H2,100,135)(H2,101,136)(H,108,114)(H,112,140)(H,113,150)(H,115,138)(H,116,137)(H,117,139)(H,118,144)(H,119,142)(H,120,153)(H,121,149)(H,122,146)(H,123,141)(H,124,151)(H,125,143)(H,126,145)(H,127,147)(H,128,148)(H,129,152)(H,155,156)(H4,102,103,109)(H4,104,105,110)(H4,106,107,111)/t49-,50-,51+,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,75-,76-,77-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50046553
(CHEMBL437421 | Tyr-Pro-Ser-Lys-Pro-(D-Ala)-Arg-His...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCNC(=O)CC[C@H](NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C105H161N33O26/c1-6-56(4)84-99(160)128-71(91(152)124-68(19-12-42-119-104(112)113)86(147)127-70(35-37-81(108)143)90(151)125-69(20-13-43-120-105(114)115)89(150)134-77(102(163)164)49-60-27-33-64(142)34-28-60)36-38-83(145)117-40-10-8-16-66(87(148)133-76(51-82(109)144)94(155)130-73(46-55(2)3)95(156)136-84)126-92(153)74(48-59-25-31-63(141)32-26-59)131-93(154)75(50-61-52-116-54-121-61)132-88(149)67(18-11-41-118-103(110)111)123-85(146)57(5)122-97(158)79-21-15-45-138(79)101(162)72(17-7-9-39-106)129-96(157)78(53-139)135-98(159)80-22-14-44-137(80)100(161)65(107)47-58-23-29-62(140)30-24-58/h23-34,52,54-57,65-80,84,139-142H,6-22,35-51,53,106-107H2,1-5H3,(H2,108,143)(H2,109,144)(H,116,121)(H,117,145)(H,122,158)(H,123,146)(H,124,152)(H,125,151)(H,126,153)(H,127,147)(H,128,160)(H,129,157)(H,130,155)(H,131,154)(H,132,149)(H,133,148)(H,134,150)(H,135,159)(H,136,156)(H,163,164)(H4,110,111,118)(H4,112,113,119)(H4,114,115,120)/t56-,57+,65+,66-,67-,68-,69-,70-,71-,72-,73+,74-,75-,76-,77-,78-,79+,80-,84-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cells |
J Med Chem 36: 385-93 (1993)
BindingDB Entry DOI: 10.7270/Q2WS8S96 |
More data for this
Ligand-Target Pair | |
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