Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor 3 (RAT) | BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 0.00220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | 0.00270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | 0.00390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 0.00520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM50088453 (1-(6-Bromo-5-ethoxy-pyridin-3-yl)-[1,4]diazepane |...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.0670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 0.0810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.0970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50088453 (1-(6-Bromo-5-ethoxy-pyridin-3-yl)-[1,4]diazepane |...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50088454 (1-(6-Bromo-pyridin-3-yl)-[1,4]diazepane | 1-(6-bro...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM92377 (NS3573, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50088438 (1-(pyridin-3-yl)-1,4-diazepane | 1-Pyridin-3-yl-[1...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50088437 (1-(5-Phenyl-pyridin-3-yl)-[1,4]diazepane | CHEMBL3...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM86311 (CAS_485-35-8 | Cytisine | Cytisine-(-) | NSC_22407...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM50088454 (1-(6-Bromo-pyridin-3-yl)-[1,4]diazepane | 1-(6-bro...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50126763 ((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 2.13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM92377 (NS3573, 2) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50126764 ((S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid UniChem Similars | Article PubMed | 2.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM50088438 (1-(pyridin-3-yl)-1,4-diazepane | 1-Pyridin-3-yl-[1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50426285 (CHEMBL2312403) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50295042 ((S)-2-Amino-3-((RS)-3-hydroxy-8-methyl-7,8-dihydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.08 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50004108 ((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM86311 (CAS_485-35-8 | Cytisine | Cytisine-(-) | NSC_22407...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine-binding protein (Lymnaea stagnalis) | BDBM50088437 (1-(5-Phenyl-pyridin-3-yl)-[1,4]diazepane | CHEMBL3...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50426289 (CHEMBL2312683) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50426290 (CHEMBL2312682) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen | Assay Description Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti... | J Biol Chem 287: 4248-59 (2012) Article DOI: 10.1074/jbc.M111.292243 BindingDB Entry DOI: 10.7270/Q2J964Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Displayed 1 to 50 (of 473 total ) | Next | Last >> |