Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50256911 (CHEMBL4095621) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo Gansu Province, China. Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting method | Bioorg Med Chem Lett 27: 2119-2123 (2017) Article DOI: 10.1016/j.bmcl.2017.03.067 BindingDB Entry DOI: 10.7270/Q2668GMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50256914 (CHEMBL4061665) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo Gansu Province, China. Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting method | Bioorg Med Chem Lett 27: 2119-2123 (2017) Article DOI: 10.1016/j.bmcl.2017.03.067 BindingDB Entry DOI: 10.7270/Q2668GMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148155 (US8962612, 26) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | 0.680 | -54.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148163 (US8962612, 66) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.75 | -54.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148169 (US8962612, 80) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.850 | -53.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148165 (US8962612, 74) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.880 | -53.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148171 (US8962612, 86) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.950 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148156 (US8962612, 28) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.10 | -53.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148154 (US8962612, 23) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.10 | -53.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50256915 (CHEMBL4068851) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo Gansu Province, China. Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting method | Bioorg Med Chem Lett 27: 2119-2123 (2017) Article DOI: 10.1016/j.bmcl.2017.03.067 BindingDB Entry DOI: 10.7270/Q2668GMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135790 (US8853242, 162) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.20 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148167 (US8962612, 78) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.30 | -52.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135785 (US8853242, 152) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.30 | -50.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135780 (US8853242, 60) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.30 | -50.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135783 (US8853242, 148) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.40 | -50.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135782 (US8853242, 147) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.60 | -50.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148164 (US8962612, 69) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.60 | -52.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453766 (CHEMBL4210361) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Hospital of Lanzhou University Curated by ChEMBL | Assay Description Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes preincubated for 1 hr measured after 1hr by scintillation counting m... | Bioorg Med Chem Lett 27: 1557-1560 (2017) Article DOI: 10.1016/j.bmcl.2017.02.034 BindingDB Entry DOI: 10.7270/Q2DN47NT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135795 (US8853242, 192) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.80 | -49.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148162 (US8962612, 62) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.90 | -51.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135792 (US8853242, 170) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.90 | -49.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50222499 (CHEMBL401153 | N-(3-chlorophenyl)-2-(pyridin-4-ylm...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Inhibition of phosphorylated-Kdr after 30 mins | Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50222500 (CHEMBL250482 | N-(4-cyclohexylphenyl)-2-(pyridin-4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Inhibition of phosphorylated-Kdr after 30 mins | Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM21123 ((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo Gansu Province, China. Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting method | Bioorg Med Chem Lett 27: 2119-2123 (2017) Article DOI: 10.1016/j.bmcl.2017.03.067 BindingDB Entry DOI: 10.7270/Q2668GMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135796 (US8853242, 211) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.30 | -49.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148161 (US8962612, 61) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.5 | -51.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148157 (US8962612, 44) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.70 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148166 (US8962612, 76) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.70 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453765 (CHEMBL4215224) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Hospital of Lanzhou University Curated by ChEMBL | Assay Description Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes preincubated for 1 hr measured after 1hr by scintillation counting m... | Bioorg Med Chem Lett 27: 1557-1560 (2017) Article DOI: 10.1016/j.bmcl.2017.02.034 BindingDB Entry DOI: 10.7270/Q2DN47NT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135788 (US8853242, 160) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135789 (US8853242, 161) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.40 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148153 (US8962612, 8) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.60 | -50.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135781 (US8853242, 114) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.70 | -48.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148168 (US8962612, 79) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.70 | -50.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148160 (US8962612, 60) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.90 | -49.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50222501 (CHEMBL250684 | N-(4-chloro-3-(trifluoromethyl)phen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Inhibition of phosphorylated-Kdr after 30 mins | Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135784 (US8853242, 151) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.10 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148170 (US8962612, 81) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.20 | -49.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148152 (US8962612, 4) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.30 | -49.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50095155 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Hospital of Lanzhou University Curated by ChEMBL | Assay Description Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes preincubated for 1 hr measured after 1hr by scintillation counting m... | Bioorg Med Chem Lett 27: 1557-1560 (2017) Article DOI: 10.1016/j.bmcl.2017.02.034 BindingDB Entry DOI: 10.7270/Q2DN47NT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135794 (US8853242, 187) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.60 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135791 (US8853242, 164) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.70 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135786 (US8853242, 157) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | 5.30 | -47.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50095155 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Reproductive Medicine Special Hospital of the First Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo Gansu Province, China. Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting method | Bioorg Med Chem Lett 27: 2119-2123 (2017) Article DOI: 10.1016/j.bmcl.2017.03.067 BindingDB Entry DOI: 10.7270/Q2668GMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135793 (US8853242, 171) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.20 | -46.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148159 (US8962612, 49) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.60 | -48.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148158 (US8962612, 46) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.90 | -48.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM135787 (US8853242, 159) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.10 | -46.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astellas Pharma Inc. US Patent | Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen... | US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453764 (CHEMBL4211768) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Hospital of Lanzhou University Curated by ChEMBL | Assay Description Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes preincubated for 1 hr measured after 1hr by scintillation counting m... | Bioorg Med Chem Lett 27: 1557-1560 (2017) Article DOI: 10.1016/j.bmcl.2017.02.034 BindingDB Entry DOI: 10.7270/Q2DN47NT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50222509 (CHEMBL250228 | N-(4-chlorophenyl)-2-(pyridin-4-ylm...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Inhibition of unphosphorylated-Kdr after 30 mins | Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N | |||||||||||
More data for this Ligand-Target Pair |
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