Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285708 (US10077289, Compound 16 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50052882 (AGN-193080 | CHEMBL298936 | Imidazolidin-2-ylidene...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM50022815 ((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285706 (US10077289, Compound 14 | [(2S,3R,4R)-7-(5-Fluoro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50055832 ((1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells | J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50052880 (CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells | J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50052880 (CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285715 (US10077289, Compound 23 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285710 (US10077289, Compound 18 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285701 (US10077289, Compound 9 | [(2S,3R,4R)-1-(1H-Benzimi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285707 (US10077289, Compound 15 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM34572 (BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells | J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50021812 (2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285725 (US10077289, Compound 33 | [2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285726 (US10077289, Compound 34 | [2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285714 (US10077289, Compound 22 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285705 (US10077289, Compound 13 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285713 (US10077289, Compound 21 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285716 (US10077289, Compound 24 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285704 (US10077289, Compound 12 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285717 (US10077289, Compound 25 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for human Alpha-2A adrenergic receptor | J Med Chem 39: 1193-5 (1996) Article DOI: 10.1021/jm960012o BindingDB Entry DOI: 10.7270/Q2NZ889J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285709 (US10077289, Compound 17 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285720 (US10077289, Compound 28 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285697 (US10077289, Compound 5 | [(2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285727 (US10077289, Compound 35 | [2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285693 (US10077289, Compound 2 | [(2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (NEONATAL RAT) | BDBM50021812 (2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2B adrenergic receptor from cloned rat RNG receptor transfected into Chinese hamster ... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50055835 ((4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells | J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285695 (US10077289, Compound 4 | [(2S,3R,4R)-5-(1-(N,N-Dim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285698 (US10077289, Compound 6 | [(2S,3R,4R)-3-Hydroxy-5-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285711 (US10077289, Compound 19 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285729 (US10077289, Compound 37 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285699 (US10077289, Compound 7 | [(2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285703 (US10077289, Compound 11 | [(2S,3R,4S)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285712 (US10077289, Compound 20 | [(2S,3R,4R)-3-Hydroxy-7-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50055830 ((1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells | J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285719 (US10077289, Compound 27 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285702 (US10077289, Compound 10 | [(2S,3R,4R)-1-(1H-Benzim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285700 (US10077289, Compound 8 | [(2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285728 (US10077289, Compound 36 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285724 (US10077289, Compound 32 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (NEONATAL RAT) | BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity for rat Alpha-2B adrenergic receptor | J Med Chem 39: 1193-5 (1996) Article DOI: 10.1021/jm960012o BindingDB Entry DOI: 10.7270/Q2NZ889J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2B adrenergic receptor (NEONATAL RAT) | BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2B adrenergic receptor from cloned rat RNG receptor transfected into Chinese hamster ... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285694 (US10077289, Compound 3 | [(2S,3R,4R)-3-Hydroxy-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nischarin (Homo sapiens (Human)) | BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [3H]-clonidine from bovine imidazoline receptor I-1 | J Med Chem 39: 1193-5 (1996) Article DOI: 10.1021/jm960012o BindingDB Entry DOI: 10.7270/Q2NZ889J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50052882 (AGN-193080 | CHEMBL298936 | Imidazolidin-2-ylidene...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2C adrenergic receptor from cloned human C-2 receptor transfected into Chinese hamste... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM285723 (US10077289, Compound 31 | [(2S,3R,4R)-3-Hydroxy-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
Allergan, Inc. US Patent | Assay Description The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of... | US Patent US10077289 (2018) BindingDB Entry DOI: 10.7270/Q25B04JF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50052881 (AGN-192172 | CHEMBL49284 | Imidazolidin-2-ylidene-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst... | J Med Chem 39: 3533-8 (1996) Article DOI: 10.1021/jm960359r BindingDB Entry DOI: 10.7270/Q2PC31GF | |||||||||||
More data for this Ligand-Target Pair |
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