Compile Data Set for Download or QSAR

Found 351 hits with Last Name = 'garvey' and Initial = 'ds'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50049750 ((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...) Show SMILES C(Oc1cccnc1)[C@@H]1CCN1 |r| Show InChI InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50049750 ((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...) Show SMILES C(Oc1cccnc1)[C@@H]1CCN1 |r| Show InChI InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50049750 ((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...) Show SMILES C(Oc1cccnc1)[C@@H]1CCN1 |r| Show InChI InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081496 (5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine | CHEMBL...) Show SMILES C(Oc1cncnc1)[C@@H]1CCN1 Show InChI InChI=1S/C8H11N3O/c1-2-11-7(1)5-12-8-3-9-6-10-4-8/h3-4,6-7,11H,1-2,5H2/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50049756 (3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine |...) Show SMILES CN1CCC[C@H]1COc1cccnc1 Show InChI InChI=1S/C11H16N2O/c1-13-7-3-4-10(13)9-14-11-5-2-6-12-8-11/h2,5-6,8,10H,3-4,7,9H2,1H3/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004108 ((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...) Show SMILES CN1CCCC1c1cccnc1 Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004108 ((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...) Show SMILES CN1CCCC1c1cccnc1 Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 270: 310-8 (1994) BindingDB Entry DOI: 10.7270/Q2HH6HKJ
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50004108 ((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...) Show SMILES CN1CCCC1c1cccnc1 Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081490 (5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrimidine...) Show SMILES CN1CCC[C@H]1COc1cncnc1 Show InChI InChI=1S/C10H15N3O/c1-13-4-2-3-9(13)7-14-10-5-11-8-12-6-10/h5-6,8-9H,2-4,7H2,1H3/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha (RAT)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081484 (3-((S)-1-Methyl-pyrrolidin-3-yloxy)-pyridine | CHE...) Show SMILES CN1CC[C@@H](C1)Oc1cccnc1 Show InChI InChI=1S/C10H14N2O/c1-12-6-4-10(8-12)13-9-3-2-5-11-7-9/h2-3,5,7,10H,4,6,8H2,1H3/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50035398 ((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...) Show SMILES CN1CCC[C@H]1c1cc(C)no1 |r| Show InChI InChI=1S/C9H14N2O/c1-7-6-9(12-10-7)8-4-3-5-11(8)2/h6,8H,3-5H2,1-2H3/t8-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 270: 310-8 (1994) BindingDB Entry DOI: 10.7270/Q2HH6HKJ
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287851 ((S)-2-(3-Fluoro-phenoxymethyl)-azetidine | CHEMBL3...) Show SMILES Fc1cccc(OC[C@@H]2CCN2)c1 Show InChI InChI=1S/C10H12FNO/c11-8-2-1-3-10(6-8)13-7-9-4-5-12-9/h1-3,6,9,12H,4-5,7H2/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081483 (3-((R)-1-Methyl-pyrrolidin-3-yloxy)-pyridine | CHE...) Show SMILES CN1CC[C@H](C1)Oc1cccnc1 Show InChI InChI=1S/C10H14N2O/c1-12-6-4-10(8-12)13-9-3-2-5-11-7-9/h2-3,5,7,10H,4,6,8H2,1H3/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287814 ((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...) Show SMILES CN1CCC[C@H]1COc1cccc(F)c1 Show InChI InChI=1S/C12H16FNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha (RAT)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081487 (5-((S)-1-Methyl-azetidin-2-ylmethoxy)-pyrimidine |...) Show SMILES CN1CC[C@H]1COc1cncnc1 Show InChI InChI=1S/C9H13N3O/c1-12-3-2-8(12)6-13-9-4-10-7-11-5-9/h4-5,7-8H,2-3,6H2,1H3/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081473 (5-(1-Methyl-pyrrolidin-3-yloxy)-pyrimidine | CHEMB...) Show SMILES CN1CCC(C1)Oc1cncnc1 Show InChI InChI=1S/C9H13N3O/c1-12-3-2-8(6-12)13-9-4-10-7-11-5-9/h4-5,7-8H,2-3,6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287829 ((R)-2-(3-Fluoro-phenoxymethyl)-pyrrolidine | CHEMB...) Show SMILES Fc1cccc(OC[C@H]2CCCN2)c1 Show InChI InChI=1S/C11H14FNO/c12-9-3-1-5-11(7-9)14-8-10-4-2-6-13-10/h1,3,5,7,10,13H,2,4,6,8H2/t10-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287812 ((S)-2-(3-Fluoro-phenoxymethyl)-pyrrolidine | CHEMB...) Show SMILES Fc1cccc(OC[C@@H]2CCCN2)c1 Show InChI InChI=1S/C11H14FNO/c12-9-3-1-5-11(7-9)14-8-10-4-2-6-13-10/h1,3,5,7,10,13H,2,4,6,8H2/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287821 ((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-azetidine ...) Show SMILES CN1CC[C@H]1COc1cccc(F)c1 Show InChI InChI=1S/C11H14FNO/c1-13-6-5-10(13)8-14-11-4-2-3-9(12)7-11/h2-4,7,10H,5-6,8H2,1H3/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081476 (3-((S)-1-Azetidin-2-ylmethoxy)-6-chloro-pyridazine...) Show SMILES Clc1ccc(OC[C@@H]2CCN2)nn1 Show InChI InChI=1S/C8H10ClN3O/c9-7-1-2-8(12-11-7)13-5-6-3-4-10-6/h1-2,6,10H,3-5H2/t6-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081475 (2-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrazine |...) Show SMILES CN1CCC[C@H]1COc1cnccn1 Show InChI InChI=1S/C10H15N3O/c1-13-6-2-3-9(13)8-14-10-7-11-4-5-12-10/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287838 ((S)-2-(3,4-Difluoro-phenoxymethyl)-pyrrolidine | C...) Show SMILES Fc1ccc(OC[C@@H]2CCCN2)cc1F Show InChI InChI=1S/C11H13F2NO/c12-10-4-3-9(6-11(10)13)15-7-8-2-1-5-14-8/h3-4,6,8,14H,1-2,5,7H2/t8-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287816 ((S)-2-(3,5-Difluoro-phenoxymethyl)-pyrrolidine | C...) Show SMILES Fc1cc(F)cc(OC[C@@H]2CCCN2)c1 Show InChI InChI=1S/C11H13F2NO/c12-8-4-9(13)6-11(5-8)15-7-10-2-1-3-14-10/h4-6,10,14H,1-3,7H2/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287848 ((S)-2-(3,4-Difluoro-phenoxymethyl)-1-methyl-pyrrol...) Show SMILES CN1CCC[C@H]1COc1ccc(F)c(F)c1 Show InChI InChI=1S/C12H15F2NO/c1-15-6-2-3-9(15)8-16-10-4-5-11(13)12(14)7-10/h4-5,7,9H,2-3,6,8H2,1H3/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287834 (3-((S)-1-Pyrrolidin-2-ylmethoxy)-benzonitrile | CH...) Show SMILES N#Cc1cccc(OC[C@@H]2CCCN2)c1 Show InChI InChI=1S/C12H14N2O/c13-8-10-3-1-5-12(7-10)15-9-11-4-2-6-14-11/h1,3,5,7,11,14H,2,4,6,9H2/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287849 ((S)-2-(3,5-Difluoro-phenoxymethyl)-1-methyl-pyrrol...) Show SMILES CN1CCC[C@H]1COc1cc(F)cc(F)c1 Show InChI InChI=1S/C12H15F2NO/c1-15-4-2-3-11(15)8-16-12-6-9(13)5-10(14)7-12/h5-7,11H,2-4,8H2,1H3/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50005854 (1-(4-Azetidin-1-yl-but-2-ynyl)-pyrrolidin-2-one | ...) Show SMILES O=C1CCCN1CC#CCN1CCC1 Show InChI InChI=1S/C11H16N2O/c14-11-5-3-10-13(11)9-2-1-6-12-7-4-8-12/h3-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor M2 in rat brainstem				J Med Chem 35: 1550-7 (1992) BindingDB Entry DOI: 10.7270/Q2MK6BT7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081478 (3-((S)-1-Methyl-azetidin-2-ylmethoxy)-pyridazine |...) Show SMILES CN1CC[C@H]1COc1cccnn1 Show InChI InChI=1S/C9H13N3O/c1-12-6-4-8(12)7-13-9-3-2-5-10-11-9/h2-3,5,8H,4,6-7H2,1H3/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081497 (3-Chloro-6-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-p...) Show SMILES CN1CCC[C@H]1COc1ccc(Cl)nn1 Show InChI InChI=1S/C10H14ClN3O/c1-14-6-2-3-8(14)7-15-10-5-4-9(11)12-13-10/h4-5,8H,2-3,6-7H2,1H3/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287852 ((S)-2-(3-Chloro-phenoxymethyl)-1-methyl-pyrrolidin...) Show SMILES CN1CCC[C@H]1COc1cccc(Cl)c1 Show InChI InChI=1S/C12H16ClNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287824 ((S)-1-Methyl-2-phenoxymethyl-pyrrolidine | CHEMBL7...) Show SMILES CN1CCC[C@H]1COc1ccccc1 Show InChI InChI=1S/C12H17NO/c1-13-9-5-6-11(13)10-14-12-7-3-2-4-8-12/h2-4,7-8,11H,5-6,9-10H2,1H3/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081479 (3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridazine...) Show SMILES CN1CCC[C@H]1COc1cccnn1 Show InChI InChI=1S/C10H15N3O/c1-13-7-3-4-9(13)8-14-10-5-2-6-11-12-10/h2,5-6,9H,3-4,7-8H2,1H3/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50035406 (3-Methyl-5-((R)-1-methyl-pyrrolidin-2-yl)-isoxazol...) Show SMILES CN1CCC[C@@H]1c1cc(C)no1 Show InChI InChI=1S/C9H14N2O/c1-7-6-9(12-10-7)8-4-3-5-11(8)2/h6,8H,3-5H2,1-2H3/t8-/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 270: 310-8 (1994) BindingDB Entry DOI: 10.7270/Q2HH6HKJ
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081477 (3-Chloro-6-(1-methyl-pyrrolidin-3-yloxy)-pyridazin...) Show SMILES CN1CCC(C1)Oc1ccc(Cl)nn1 Show InChI InChI=1S/C9H12ClN3O/c1-13-5-4-7(6-13)14-9-3-2-8(10)11-12-9/h2-3,7H,4-6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287820 (3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-benzonitri...) Show SMILES CN1CCC[C@H]1COc1cccc(c1)C#N Show InChI InChI=1S/C13H16N2O/c1-15-7-3-5-12(15)10-16-13-6-2-4-11(8-13)9-14/h2,4,6,8,12H,3,5,7,10H2,1H3/t12-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287843 ((S)-2-Phenoxymethyl-azetidine | CHEMBL72031) Show SMILES C(Oc1ccccc1)[C@@H]1CCN1 Show InChI InChI=1S/C10H13NO/c1-2-4-10(5-3-1)12-8-9-6-7-11-9/h1-5,9,11H,6-8H2/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081474 (3-Chloro-6-((S)-1-methyl-azetidin-2-ylmethoxy)-pyr...) Show SMILES CN1CC[C@H]1COc1ccc(Cl)nn1 Show InChI InChI=1S/C9H12ClN3O/c1-13-5-4-7(13)6-14-9-3-2-8(10)11-12-9/h2-3,7H,4-6H2,1H3/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287825 ((S)-2-(2,3-Difluoro-phenoxymethyl)-1-methyl-pyrrol...) Show SMILES CN1CCC[C@H]1COc1cccc(F)c1F Show InChI InChI=1S/C12H15F2NO/c1-15-7-3-4-9(15)8-16-11-6-2-5-10(13)12(11)14/h2,5-6,9H,3-4,7-8H2,1H3/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287846 ((S)-2-(2,3-Difluoro-phenoxymethyl)-pyrrolidine | C...) Show SMILES Fc1cccc(OC[C@@H]2CCCN2)c1F Show InChI InChI=1S/C11H13F2NO/c12-9-4-1-5-10(11(9)13)15-7-8-3-2-6-14-8/h1,4-5,8,14H,2-3,6-7H2/t8-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50287854 ((R)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...) Show SMILES CN1CCC[C@@H]1COc1cccc(F)c1 Show InChI InChI=1S/C12H16FNO/c1-14-7-3-5-11(14)9-15-12-6-2-4-10(13)8-12/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brain				Bioorg Med Chem Lett 6: 2283-2288 (1996) Article DOI: 10.1016/0960-894X(96)00416-7 BindingDB Entry DOI: 10.7270/Q2C82999
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50004665 ((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...) Show SMILES O=C1CCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor M2 in rat brainstem				J Med Chem 35: 1550-7 (1992) BindingDB Entry DOI: 10.7270/Q2MK6BT7
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081481 (3-Chloro-6-((R)-1-methyl-pyrrolidin-2-ylmethoxy)-p...) Show SMILES CN1CCC[C@@H]1COc1ccc(Cl)nn1 Show InChI InChI=1S/C10H14ClN3O/c1-14-6-2-3-8(14)7-15-10-5-4-9(11)12-13-10/h4-5,8H,2-3,6-7H2,1H3/t8-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair

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