Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using tyramine as substrate preincubated for 1 hr f... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50462966 (CHEMBL4239843) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50093407 ((R)2-{6-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-9-is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM19187 ((2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Mahidol University Curated by ChEMBL | Assay Description Inhibition of PDGFRbeta (unknown origin) | Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4811 ((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Mahidol University Curated by ChEMBL | Assay Description Inhibition of PDGFRbeta (unknown origin) | Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7584 (1-{6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-pu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7576 (1-(6-{[(4-chlorophenyl)methyl]amino}-9-(propan-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P... | Bioorg Med Chem Lett 16: 3144-6 (2006) Article DOI: 10.1016/j.bmcl.2006.03.060 BindingDB Entry DOI: 10.7270/Q2862DPV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7584 (1-{6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-pu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7576 (1-(6-{[(4-chlorophenyl)methyl]amino}-9-(propan-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7576 (1-(6-{[(4-chlorophenyl)methyl]amino}-9-(propan-2-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Mahidol University Curated by ChEMBL | Assay Description Inhibition of VEGFR2 (unknown origin) | Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Mahidol University Curated by ChEMBL | Assay Description Inhibition of human FGFR1 expressed in insect cells by HTRF method | Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7579 (1-(6-{[4-(dimethylamino)benzyl]amino}-9-isopropyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7579 (1-(6-{[4-(dimethylamino)benzyl]amino}-9-isopropyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against cyclin-dependent kinase 5 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50462966 (CHEMBL4239843) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using tyramine as substrate preincubated for 1 hr f... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7574 (1-(6-{[(4-ethoxyphenyl)methyl]amino}-9-(propan-2-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7553 (1-{2-[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7574 (1-(6-{[(4-ethoxyphenyl)methyl]amino}-9-(propan-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7577 (1-{6-[(1,3-benzodioxol-5-ylmethyl)amino]-9-isoprop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7555 (1-[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7554 (5-[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7582 (1-{6-[(4-ethoxyphenyl)amino]-9-(propan-2-yl)-9H-pu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7577 (1-{6-[(1,3-benzodioxol-5-ylmethyl)amino]-9-isoprop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7583 (1-{6-[(3,4-dichlorophenyl)amino]-9-(propan-2-yl)-9...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7582 (1-{6-[(4-ethoxyphenyl)amino]-9-(propan-2-yl)-9H-pu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7581 (1-{6-[(4-methoxyphenyl)amino]-9-(propan-2-yl)-9H-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7581 (1-{6-[(4-methoxyphenyl)amino]-9-(propan-2-yl)-9H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7555 (1-[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7583 (1-{6-[(3,4-dichlorophenyl)amino]-9-(propan-2-yl)-9...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50462946 (CHEMBL4249189) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 203 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50462954 (CHEMBL4246570) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50093414 ((R){1-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-pu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of cyclin-dependent kinase 1 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50462960 (CHEMBL4239660) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7573 (1-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P... | Bioorg Med Chem Lett 16: 3144-6 (2006) Article DOI: 10.1016/j.bmcl.2006.03.060 BindingDB Entry DOI: 10.7270/Q2862DPV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7573 (1-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of cyclin-dependent kinase 1 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7573 (1-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM7576 (1-(6-{[(4-chlorophenyl)methyl]amino}-9-(propan-2-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against cyclin-dependent kinase 5 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM7579 (1-(6-{[4-(dimethylamino)benzyl]amino}-9-isopropyl-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against cyclin-dependent kinase 5 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50462942 (CHEMBL4244643) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 264 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using benzylamine as substrate preincubated for 1 h... | J Med Chem 61: 7043-7064 (2018) Article DOI: 10.1021/acs.jmedchem.7b01588 BindingDB Entry DOI: 10.7270/Q2VT1VSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50093433 ((R){1-[9-Isopropyl-6-(3-methoxy-benzylamino)-9H-pu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of cyclin-dependent kinase 1 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50093425 ((R)[1-(9-Isopropyl-6-phenylamino-9H-purin-2-yl)-py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM7581 (1-{6-[(4-methoxyphenyl)amino]-9-(propan-2-yl)-9H-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against cyclin-dependent kinase 5 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM7580 (1-(6-anilino-9-isopropyl-9H-purin-2-yl)-3-methylpe...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against cyclin-dependent kinase 5 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50093424 ((R){1-[6-(4-Bromo-phenylamino)-9-isopropyl-9H-puri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM7577 (1-{6-[(1,3-benzodioxol-5-ylmethyl)amino]-9-isoprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity against cyclin-dependent kinase 5 | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7578 (1-(6-{[(3,4-dimethoxyphenyl)methyl]amino}-9-(propa...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Curie Curated by ChEMBL | Assay Description Inhibition of Cyclin-dependent kinase 1 (CDK1) | J Med Chem 43: 4098-108 (2000) BindingDB Entry DOI: 10.7270/Q24B321Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish)) | BDBM7578 (1-(6-{[(3,4-dimethoxyphenyl)methyl]amino}-9-(propa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Institut Curie | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... | J Med Chem 43: 1282-92 (2000) Article DOI: 10.1021/jm9911130 BindingDB Entry DOI: 10.7270/Q2K935R2 | |||||||||||
More data for this Ligand-Target Pair |
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