Compile Data Set for Download or QSAR

Found 26 hits with Last Name = 'grosicki' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021553 (CHEMBL3290570) Show SMILES CN1CCN(CC1)c1ncnc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H16ClN5/c1-19-6-8-20(9-7-19)14-17-10-16-13(18-14)11-2-4-12(15)5-3-11/h2-5,10H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor after 45 mins by scintillation counting analysis				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021536 (CHEMBL3290576) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021531 (CHEMBL3290577) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H17FN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	378	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021549 (CHEMBL3290573) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C14H17ClN6/c1-20-5-7-21(8-6-20)14-18-12(17-13(16)19-14)10-3-2-4-11(15)9-10/h2-4,9H,5-8H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	408	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021555 (CHEMBL3290580) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(C)cc1 Show InChI InChI=1S/C15H20N6/c1-11-3-5-12(6-4-11)13-17-14(16)19-15(18-13)21-9-7-20(2)8-10-21/h3-6H,7-10H2,1-2H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	431	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021529 (CHEMBL3290578) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H17BrN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	524	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021562 (CHEMBL3290586) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H16Cl2N6/c1-21-4-6-22(7-5-21)14-19-12(18-13(17)20-14)9-2-3-10(15)11(16)8-9/h2-3,8H,4-7H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021567 (CHEMBL3290591) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(C)c(C)c1 Show InChI InChI=1S/C16H22N6/c1-11-4-5-13(10-12(11)2)14-18-15(17)20-16(19-14)22-8-6-21(3)7-9-22/h4-5,10H,6-9H2,1-3H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	834	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021552 (CHEMBL3290571) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccccc1 Show InChI InChI=1S/C14H18N6/c1-19-7-9-20(10-8-19)14-17-12(16-13(15)18-14)11-5-3-2-4-6-11/h2-6H,7-10H2,1H3,(H2,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021564 (CHEMBL3290588) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C14H16F2N6/c1-21-2-4-22(5-3-21)14-19-12(18-13(17)20-14)9-6-10(15)8-11(16)7-9/h6-8H,2-5H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021551 (CHEMBL3290572) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccccc1Cl Show InChI InChI=1S/C14H17ClN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-4-2-3-5-11(10)15/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021559 (CHEMBL3290584) Show SMILES COc1ccc(cc1Cl)-c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C15H19ClN6O/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)10-3-4-12(23-2)11(16)9-10/h3-4,9H,5-8H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021547 (CHEMBL3290574) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1cccc(C)c1 Show InChI InChI=1S/C15H20N6/c1-11-4-3-5-12(10-11)13-17-14(16)19-15(18-13)21-8-6-20(2)7-9-21/h3-5,10H,6-9H2,1-2H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021565 (CHEMBL3290589) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C14H15F3N6/c1-22-2-4-23(5-3-22)14-20-12(19-13(18)21-14)8-6-9(15)11(17)10(16)7-8/h6-7H,2-5H2,1H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021557 (CHEMBL3290582) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C15H17N7/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)12-4-2-11(10-16)3-5-12/h2-5H,6-9H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021554 (CHEMBL3290579) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(I)cc1 Show InChI InChI=1S/C14H17IN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021556 (CHEMBL3290581) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H17F3N6/c1-23-6-8-24(9-7-23)14-21-12(20-13(19)22-14)10-2-4-11(5-3-10)15(16,17)18/h2-5H,6-9H2,1H3,(H2,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021563 (CHEMBL3290587) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1c(F)cccc1F Show InChI InChI=1S/C14H16F2N6/c1-21-5-7-22(8-6-21)14-19-12(18-13(17)20-14)11-9(15)3-2-4-10(11)16/h2-4H,5-8H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021544 (CHEMBL3290575) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1cccc(c1)C#N Show InChI InChI=1S/C15H17N7/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)12-4-2-3-11(9-12)10-16/h2-4,9H,5-8H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021561 (CHEMBL3290585) Show SMILES COc1ccc(Cl)cc1-c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C15H19ClN6O/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)11-9-10(16)3-4-12(11)23-2/h3-4,9H,5-8H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021566 (CHEMBL3290590) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C16H22N6/c1-11-8-12(2)10-13(9-11)14-18-15(17)20-16(19-14)22-6-4-21(3)5-7-22/h8-10H,4-7H2,1-3H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50021536 (CHEMBL3290576) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membrane after 90 mins				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50021529 (CHEMBL3290578) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H17BrN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cell membrane after 90 mins				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021558 (CHEMBL3290583) Show SMILES CN(C)c1ccc(cc1)-c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C16H23N7/c1-21(2)13-6-4-12(5-7-13)14-18-15(17)20-16(19-14)23-10-8-22(3)9-11-23/h4-7H,8-11H2,1-3H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021536 (CHEMBL3290576) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at human histamine H4 receptor expressed in gamma-irradiated recombinant CHO cells assessed as inhibition of forskolin/histamine-...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021529 (CHEMBL3290578) Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H17BrN6/c1-20-6-8-21(9-7-20)14-18-12(17-13(16)19-14)10-2-4-11(15)5-3-10/h2-5H,6-9H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at human histamine H4 receptor expressed in gamma-irradiated recombinant CHO cells assessed as inhibition of forskolin/histamine-...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair