Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193676 (US9670208, Example 295 4-(3-(cyclopropylmethyl)-[1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193385 (US9670208, Example 57) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193773 (US9670208, Example 402 4-(3-(4-fluorobenzyl)-[1,2,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350052 (US10208024, Example 51 | US10766881, Example 51) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350052 (US10208024, Example 51 | US10766881, Example 51) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193675 (US9670208, Example 279 N-(1-methyl-1H-pyrazol-5-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM350059 (US10208024, Example 58 | US10766881, Example 58) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 [397-806] (Homo sapiens (Human)) | BDBM350059 (US10208024, Example 58 | US10766881, Example 58) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Homo sapiens (Human)) | BDBM50105186 (4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of selectin E in human endothelial cells | J Med Chem 44: 3469-87 (2001) BindingDB Entry DOI: 10.7270/Q2KW5FBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193672 (US9670208, Example 278 4-(3-(pyridin-2-ylmethyl)-[...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193381 (US9670208, Example 49) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM191370 (US9670208, Example 35) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350042 (US10208024, Example 41 | US10766881, Example 41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350042 (US10208024, Example 41 | US10766881, Example 41) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193781 (US9670208, Example 493 4-(3-((6-ethoxypyridin-3-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350051 (US10208024, Example 50 | US10766881, Example 50) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193412 (US9670208, Example 276 N-(1-methyl-1H-pyrazol-5-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193410 (US9670208, Example 272 4-(3-((6-methoxypyridin-3-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350051 (US10208024, Example 50 | US10766881, Example 50) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193396 (US9670208, Example 121) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193776 (US9670208, Example 403 4-(3-(3-fluoro-4-methoxyben...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193756 (US9670208, Example 317 4-(3-((4,4-difluorocyclohex...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350049 (6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350049 (6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM350052 (US10208024, Example 51 | US10766881, Example 51) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50105186 (4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cells | J Med Chem 44: 3469-87 (2001) BindingDB Entry DOI: 10.7270/Q2KW5FBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Homo sapiens (Human)) | BDBM50105151 (4-(4-Vinyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of selectin E in human endothelial cells | J Med Chem 44: 3469-87 (2001) BindingDB Entry DOI: 10.7270/Q2KW5FBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 [397-806] (Homo sapiens (Human)) | BDBM350052 (US10208024, Example 51 | US10766881, Example 51) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350082 (US10208024, Example 81 | US10766881, Example 81) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350082 (US10208024, Example 81 | US10766881, Example 81) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350050 (6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350033 (US10208024, Example 32 | US10766881, Example 32) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350050 (6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350033 (US10208024, Example 32 | US10766881, Example 32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 [397-806] (Homo sapiens (Human)) | BDBM350049 (6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350045 (US10208024, Example 44 | US10766881, Example 44) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350043 (US10208024, Example 42 | US10766881, Example 42) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350043 (US10208024, Example 42 | US10766881, Example 42) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50105227 (4-[4-(Tetrahydro-pyran-2-yloxymethyl)-phenoxy]-thi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cells | J Med Chem 44: 3469-87 (2001) BindingDB Entry DOI: 10.7270/Q2KW5FBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350032 (US10208024, Example 31 | US10766881, Example 31) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM350049 (6-(3-amino-6-(1-methyl- 1H-pyrazol-4-yl)pyrazin- 2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350045 (US10208024, Example 44 | US10766881, Example 44) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM350032 (US10208024, Example 31 | US10766881, Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 [403-822] (Homo sapiens (Human)) | BDBM462139 (US10766881, Example 60) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM350048 (US10208024, Example 47 | US10766881, Example 47) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350061 (US10208024, Example 60) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 1 [8-360] (Homo sapiens (Human)) | BDBM193411 (US9670208, Example 275 N-(1-methyl-1H-pyrazol-5-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | 7.3 | n/a |
Array BioPharma Inc.; Genentech, Inc. US Patent | Assay Description Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro... | US Patent US9670208 (2017) BindingDB Entry DOI: 10.7270/Q2RJ4GMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 [397-806] (Homo sapiens (Human)) | BDBM350048 (US10208024, Example 47 | US10766881, Example 47) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array Biopharma Inc. US Patent | US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350048 (US10208024, Example 47 | US10766881, Example 47) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM350044 (US10208024, Example 43 | US10766881, Example 43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc. US Patent | Assay Description FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor... | US Patent US10208024 (2019) BindingDB Entry DOI: 10.7270/Q2CJ8GNW | |||||||||||
More data for this Ligand-Target Pair |
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