Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464108 (CHEMBL4241824) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to human integrin alphaVbeta6 assessed as dissociation constant up to 48 hrs by liquid scintillation counting | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464104 (CHEMBL4244784) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464110 (CHEMBL4238909) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to human integrin alphaVbeta6 assessed as dissociation constant up to 48 hrs by liquid scintillation counting | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464123 (CHEMBL4242263) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464124 (CHEMBL4249629) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464119 (CHEMBL4241584) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464108 (CHEMBL4241824) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 0.0398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464118 (CHEMBL4249172) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464120 (CHEMBL4237919) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464100 (CHEMBL4243367) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464110 (CHEMBL4238909) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464097 (CHEMBL4237868) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464113 (CHEMBL4239085) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464098 (CHEMBL4242635) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464112 (CHEMBL4248589) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50464115 (CHEMBL4247149) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assay | J Med Chem 61: 8417-8443 (2018) Article DOI: 10.1021/acs.jmedchem.8b00959 BindingDB Entry DOI: 10.7270/Q24T6N25 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277429 (US10072026, Example 1-23 | US10947254, Example 1-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277399 (N5-((1R,3s,5S)-9-(ethylsulfonyl)-9-azabicyclo[3.3....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277399 (N5-((1R,3s,5S)-9-(ethylsulfonyl)-9-azabicyclo[3.3....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277400 (1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)am...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277400 (1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)am...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM277400 (1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)am...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277402 (1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)am...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277402 (1-(((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)am...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277403 (N5-((1R,3s,5S)-9-((5-fluoropyridin-3-yl)sulfonyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277403 (N5-((1R,3s,5S)-9-((5-fluoropyridin-3-yl)sulfonyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277404 (N7-(5-methyl-1H-pyrazol-3-yl)-2-(morpholinomethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277599 (US10072026, Example 6-18 | US10947254, Example 6-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277599 (US10072026, Example 6-18 | US10947254, Example 6-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277604 (US10072026, Example 6-23 | US10947254, Example 6-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277406 (N-methyl-2-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277585 (US10072026, Example 6-4 | US10947254, Example 6-4 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277586 (US10072026, Example 6-5 | US10947254, Example 6-5 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277587 (US10072026, Example 6-6 | US10947254, Example 6-6 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277395 (N5-((1R,3s,5S)-8-((2-methoxyethyl)sulfonyl)-8-azab...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277590 (US10072026, Example 6-9 | US10947254, Example 6-9 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277390 (3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)ami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277390 (3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)ami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277396 (N5-((1R,3s,5S)-8-(ethylsulfonyl)-8-azabicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277397 (N7-(5-methyl-1H-pyrazol-3-yl)-N5-((1R,3s,5S)-9-(py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277397 (N7-(5-methyl-1H-pyrazol-3-yl)-N5-((1R,3s,5S)-9-(py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277559 (US10072026, Example 5-21 | US10947254, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277560 (US10072026, Example 5-22 | US10947254, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277561 (US10072026, Example 5-23 | US10947254, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277561 (US10072026, Example 5-23 | US10947254, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM277564 (US10072026, Example 5-26 | US11780852, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277564 (US10072026, Example 5-26 | US11780852, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM277564 (US10072026, Example 5-26 | US11780852, Example 5-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277567 (US10072026, Example 5-29) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM277568 (US10072026, Example 5-30 | US10947254, Example 5-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10072026 (2018) BindingDB Entry DOI: 10.7270/Q2G162VM | |||||||||||
More data for this Ligand-Target Pair |
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