Compile Data Set for Download or QSAR

Found 954 hits with Last Name = 'hamon' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50063266 (6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...) Show SMILES [O-][N+](=O)c1ccc2nc(ccc2c1)N1CCNCC1 Show InChI InChI=1S/C13H14N4O2/c18-17(19)11-2-3-12-10(9-11)1-4-13(15-12)16-7-5-14-6-8-16/h1-4,9,14H,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]paroxetine bound to Serotonin transporter receptor in rat forebrain				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50063266 (6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...) Show SMILES [O-][N+](=O)c1ccc2nc(ccc2c1)N1CCNCC1 Show InChI InChI=1S/C13H14N4O2/c18-17(19)11-2-3-12-10(9-11)1-4-13(15-12)16-7-5-14-6-8-16/h1-4,9,14H,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity towards Serotonin transporter was determined in rat forebrain membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM81789 (5-CT,DP | CAS_156314 | DP-5-CT | NN-DIPROP-5-CT | ...) Show SMILES CCCN(CCC)CCc1c[nH]c2ccc(cc12)C(N)=O Show InChI InChI=1S/C17H25N3O/c1-3-8-20(9-4-2)10-7-14-12-19-16-6-5-13(17(18)21)11-15(14)16/h5-6,11-12,19H,3-4,7-10H2,1-2H3,(H2,18,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) Show SMILES NCCc1c[nH]c2ccc(cc12)C(N)=O Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM82368 (CAS_121851 | CHEMBL11592 | CHEMBL301060 | NSC_1218...) Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1 Show InChI InChI=1S/C26H38N2O4/c1-3-13-27(20-16-21-22(31-2)9-8-10-23(21)32-19-20)14-6-7-15-28-24(29)17-26(18-25(28)30)11-4-5-12-26/h8-10,20H,3-7,11-19H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50063263 (6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c2CCCCc12 Show InChI InChI=1S/C18H23N3/c1-20-10-12-21(13-11-20)18-16-8-3-2-6-14(16)15-7-4-5-9-17(15)19-18/h4-5,7,9H,2-3,6,8,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50063263 (6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c2CCCCc12 Show InChI InChI=1S/C18H23N3/c1-20-10-12-21(13-11-20)18-16-8-3-2-6-14(16)15-7-4-5-9-17(15)19-18/h4-5,7,9H,2-3,6,8,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50035508 (4-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(I)cc2)c2ccccn2)CC1 Show InChI InChI=1S/C25H27IN4O2/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20/h2-13H,14-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50033112 (6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyla...) Show SMILES COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1 Show InChI InChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50449636 (BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...) Show SMILES [H][C@]12CCC[C@]([H])(C[C@H](C1)NC(=O)c1nn(C)c3ccccc13)N2C |r,TLB:24:23:8.9.7:2.4.3| Show InChI InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)/t12-,13-,14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076415 (2-[2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinolin-3...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(-c2ccccc2)c1CCO Show InChI InChI=1S/C22H25N3O/c1-24-12-14-25(15-13-24)22-19(11-16-26)21(17-7-3-2-4-8-17)18-9-5-6-10-20(18)23-22/h2-10,26H,11-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50060685 (9-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...) Show SMILES CN1CCN(CC1)c1nc2cccc(F)c2n2cccc12 Show InChI InChI=1S/C16H17FN4/c1-19-8-10-20(11-9-19)16-14-6-3-7-21(14)15-12(17)4-2-5-13(15)18-16/h2-7H,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50299661 (9-methyl-4-(4-((3H-imidazol-4-yl)methyl)piperazin-...) Show SMILES Cc1cccc2nc(N3CCN(Cc4cnc[nH]4)CC3)c3cccn3c12 Show InChI InChI=1S/C20H22N6/c1-15-4-2-5-17-19(15)26-7-3-6-18(26)20(23-17)25-10-8-24(9-11-25)13-16-12-21-14-22-16/h2-7,12,14H,8-11,13H2,1H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076401 (CHEMBL41511 | [2-(4-Methyl-piperazin-1-yl)-4-pheny...) Show SMILES CCOC(=O)Cc1c(nc2ccccc2c1-c1ccccc1)N1CCN(C)CC1 Show InChI InChI=1S/C24H27N3O2/c1-3-29-22(28)17-20-23(18-9-5-4-6-10-18)19-11-7-8-12-21(19)25-24(20)27-15-13-26(2)14-16-27/h4-12H,3,13-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076416 (2-[4-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(c1CCO)-c1ccccc1F |(19.39,-9.64,;18.06,-8.87,;18.06,-7.32,;16.71,-6.51,;15.38,-7.32,;15.38,-8.87,;16.72,-9.64,;14.04,-6.56,;12.7,-7.35,;11.36,-6.56,;10.01,-7.35,;8.68,-6.58,;8.68,-5.02,;10.01,-4.25,;11.36,-5.02,;12.69,-4.24,;14.02,-5,;15.35,-4.23,;16.7,-4.98,;18.03,-4.21,;12.67,-2.71,;14,-1.94,;14,-.4,;12.66,.37,;11.32,-.43,;11.34,-1.96,;10.01,-2.75,)| Show InChI InChI=1S/C22H24FN3O/c1-25-11-13-26(14-12-25)22-18(10-15-27)21(16-6-2-4-8-19(16)23)17-7-3-5-9-20(17)24-22/h2-9,27H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50299660 (7-fluoro-4-(4-((3H-imidazol-4-yl)methyl)piperazin-...) Show SMILES Fc1ccc2c(c1)nc(N1CCN(Cc3cnc[nH]3)CC1)c1cccn21 Show InChI InChI=1S/C19H19FN6/c20-14-3-4-17-16(10-14)23-19(18-2-1-5-26(17)18)25-8-6-24(7-9-25)12-15-11-21-13-22-15/h1-5,10-11,13H,6-9,12H2,(H,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50081973 (4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinoxal...) Show SMILES CN1CCN(CC1)c1nc2cc(O)ccc2n2cccc12 Show InChI InChI=1S/C16H18N4O/c1-18-7-9-19(10-8-18)16-15-3-2-6-20(15)14-5-4-12(21)11-13(14)17-16/h2-6,11,21H,7-10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]zacopride from 5HT3 receptor in rat cortex				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM82367 (CAS_141533-35-9 | SDZ 216,525 | SDZ 216-525) Show SMILES COC(=O)c1cc2c(cccc2[nH]1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C25H28N4O5S/c1-34-25(31)21-17-19-20(26-21)8-6-9-22(19)28-15-13-27(14-16-28)11-4-5-12-29-24(30)18-7-2-3-10-23(18)35(29,32)33/h2-3,6-10,17,26H,4-5,11-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076408 (4-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-3-...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(c1CCOC1CCCO1)-c1ccccc1F |(19.39,-9.64,;18.06,-8.87,;18.06,-7.32,;16.71,-6.51,;15.38,-7.32,;15.38,-8.87,;16.72,-9.64,;14.04,-6.56,;12.7,-7.35,;11.36,-6.56,;10.01,-7.35,;8.68,-6.58,;8.68,-5.02,;10.01,-4.25,;11.36,-5.02,;12.69,-4.24,;14.02,-5,;15.35,-4.23,;16.7,-4.98,;18.03,-4.21,;19.36,-4.95,;19.54,-6.48,;21.04,-6.79,;21.81,-5.44,;20.76,-4.31,;12.67,-2.71,;14,-1.94,;14,-.4,;12.66,.37,;11.32,-.43,;11.34,-1.96,;10.01,-2.75,)| Show InChI InChI=1S/C26H30FN3O2/c1-29-13-15-30(16-14-29)26-21(12-18-32-24-11-6-17-31-24)25(19-7-2-4-9-22(19)27)20-8-3-5-10-23(20)28-26/h2-5,7-10,24H,6,11-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50451023 (MESULERGINE) Show SMILES [H][C@@]12Cc3cn(C)c4cccc(c34)[C@@]1([H])C[C@H](CNS(=O)(=O)N(C)C)CN2C |r| Show InChI InChI=1S/C19H28N4O2S/c1-21(2)26(24,25)20-10-13-8-16-15-6-5-7-17-19(15)14(12-23(17)4)9-18(16)22(3)11-13/h5-7,12-13,16,18,20H,8-11H2,1-4H3/t13-,16-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]mesulergine bound to 5-hydroxytryptamine 2C receptor in rat cortex				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50081969 (9-Methyl-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...) Show SMILES CN1CCN(CC1)c1nc2cccc(C)c2n2cccc12 Show InChI InChI=1S/C17H20N4/c1-13-5-3-6-14-16(13)21-8-4-7-15(21)17(18-14)20-11-9-19(2)10-12-20/h3-8H,9-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50081969 (9-Methyl-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...) Show SMILES CN1CCN(CC1)c1nc2cccc(C)c2n2cccc12 Show InChI InChI=1S/C17H20N4/c1-13-5-3-6-14-16(13)21-8-4-7-15(21)17(18-14)20-11-9-19(2)10-12-20/h3-8H,9-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]zacopride from 5HT3 receptor in rat cortex				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50060688 (7-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...) Show SMILES CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C16H17FN4/c1-19-7-9-20(10-8-19)16-15-3-2-6-21(15)14-5-4-12(17)11-13(14)18-16/h2-6,11H,7-10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50258431 (CHEMBL523716 | [4-(7-Fluoropyrrolo[1,2-a]quinoxali...) Show SMILES ONC(=N)CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C17H19FN6O/c18-12-3-4-14-13(10-12)20-17(15-2-1-5-24(14)15)23-8-6-22(7-9-23)11-16(19)21-25/h1-5,10,25H,6-9,11H2,(H2,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076427 (2-(4-Methyl-piperazin-1-yl)-4-phenyl-3-[2-(tetrahy...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(c1CCOC1CCCO1)-c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-28-14-16-29(17-15-28)26-22(13-19-31-24-12-7-18-30-24)25(20-8-3-2-4-9-20)21-10-5-6-11-23(21)27-26/h2-6,8-11,24H,7,12-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50060688 (7-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...) Show SMILES CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C16H17FN4/c1-19-7-9-20(10-8-19)16-15-3-2-6-21(15)14-5-4-12(17)11-13(14)18-16/h2-6,11H,7-10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50063260 (10-(4-methylhexahydro-1-pyrazinyl)-9-azatetracyclo...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c2C3CCC(C3)Cc12 Show InChI InChI=1S/C20H25N3/c1-22-8-10-23(11-9-22)20-17-13-14-6-7-15(12-14)19(17)16-4-2-3-5-18(16)21-20/h2-5,14-15H,6-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076410 (2-[2-(4-Methyl-piperazin-1-yl)-3-vinyl-quinolin-4-...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(c1C=C)-c1ccccc1O |(19.39,-9.64,;18.06,-8.87,;16.72,-9.64,;15.38,-8.87,;15.38,-7.32,;16.71,-6.51,;18.06,-7.32,;14.04,-6.56,;12.7,-7.35,;11.36,-6.56,;10.01,-7.35,;8.68,-6.58,;8.68,-5.02,;10.01,-4.25,;11.36,-5.02,;12.69,-4.24,;14.02,-5,;15.35,-4.23,;16.7,-4.98,;12.67,-2.71,;14,-1.94,;14,-.4,;12.66,.37,;11.32,-.43,;11.34,-1.96,;10.01,-2.75,)| Show InChI InChI=1S/C22H23N3O/c1-3-16-21(18-9-5-7-11-20(18)26)17-8-4-6-10-19(17)23-22(16)25-14-12-24(2)13-15-25/h3-11,26H,1,12-15H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076421 (CHEMBL42912 | [2-(4-Methyl-piperazin-1-yl)-4-pheny...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(-c2ccccc2)c1CO Show InChI InChI=1S/C21H23N3O/c1-23-11-13-24(14-12-23)21-18(15-25)20(16-7-3-2-4-8-16)17-9-5-6-10-19(17)22-21/h2-10,25H,11-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM82366 (5-OME-3-ADTN) Show SMILES COc1c(O)c(O)cc2CCC(N)Cc12 Show InChI InChI=1S/C11H15NO3/c1-15-11-8-5-7(12)3-2-6(8)4-9(13)10(11)14/h4,7,13-14H,2-3,5,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U.288 Curated by PDSP Ki Database									Neuropsychopharmacology 3: 349-60 (1990) BindingDB Entry DOI: 10.7270/Q2N29VFS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1B receptor of rat striatum.				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]5-HT bound to 5-hydroxytryptamine 1B receptor in rat striatum				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligand				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM85330 (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C Show InChI InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligand				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A (RAT)	BDBM50258495 ((R)-2-Amino-3-[4-(7-fluoropyrrolo[1,2-a]quinoxalin...) Show SMILES N[C@H](CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12)C(O)=O |r| Show InChI InChI=1S/C18H20FN5O2/c19-12-3-4-15-14(10-12)21-17(16-2-1-5-24(15)16)23-8-6-22(7-9-23)11-13(20)18(25)26/h1-5,10,13H,6-9,11,20H2,(H,25,26)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011247 (7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampus tissue.				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OHDPAT from 5HT1A receptor in rat hippocampus				J Med Chem 52: 6946-50 (2009) Article DOI: 10.1021/jm901126m BindingDB Entry DOI: 10.7270/Q2H9963M
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OHDPAT from 5HT1A receptor in rat hippocampus				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50031932 (7-(4-Methyl-piperazin-1-yl)-6H-5-oxa-8-aza-benzo[c...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c-2c1COc1ccccc-21 Show InChI InChI=1S/C21H21N3O/c1-23-10-12-24(13-11-23)21-17-14-25-19-9-5-3-7-16(19)20(17)15-6-2-4-8-18(15)22-21/h2-9H,10-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligand				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50031942 ((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...) Show SMILES CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34 |r,c:24| Show InChI InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50063264 (6-Piperazin-1-yl-7,8,9,10-tetrahydro-phenanthridin...) Show SMILES C1CCc2c(C1)c(nc1ccccc21)N1CCNCC1 Show InChI InChI=1S/C17H21N3/c1-2-7-15-13(5-1)14-6-3-4-8-16(14)19-17(15)20-11-9-18-10-12-20/h3-4,6,8,18H,1-2,5,7,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membrane				J Med Chem 41: 728-41 (1998) Article DOI: 10.1021/jm970645i BindingDB Entry DOI: 10.7270/Q2QV3N6F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50014407 (2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...) Show SMILES C1CN(CCN1)c1ccc2ccccc2n1 Show InChI InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076396 (2-(4-Methyl-piperazin-1-yl)-indeno[1,2,3-de]quinol...) Show SMILES CN1CCN(CC1)c1cc2-c3ccccc3-c3cccc(n1)c23 Show InChI InChI=1S/C20H19N3/c1-22-9-11-23(12-10-22)19-13-17-15-6-3-2-5-14(15)16-7-4-8-18(21-19)20(16)17/h2-8,13H,9-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50076422 (4-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-3-...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c(c1CCOC1CCCCO1)-c1ccccc1F |(19.39,-9.64,;18.06,-8.87,;18.06,-7.32,;16.71,-6.51,;15.38,-7.32,;15.38,-8.87,;16.72,-9.64,;14.04,-6.56,;12.7,-7.35,;11.36,-6.56,;10.01,-7.35,;8.68,-6.58,;8.68,-5.02,;10.01,-4.25,;11.36,-5.02,;12.69,-4.24,;14.02,-5,;15.35,-4.23,;16.7,-4.98,;18.03,-4.21,;19.36,-4.95,;20.67,-4.16,;22.02,-4.92,;22.05,-6.46,;20.71,-7.25,;19.36,-6.49,;12.67,-2.71,;14,-1.94,;14,-.4,;12.66,.37,;11.32,-.43,;11.34,-1.96,;10.01,-2.75,)| Show InChI InChI=1S/C27H32FN3O2/c1-30-14-16-31(17-15-30)27-22(13-19-33-25-12-6-7-18-32-25)26(20-8-2-4-10-23(20)28)21-9-3-5-11-24(21)29-27/h2-5,8-11,25H,6-7,12-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair

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