Compile Data Set for Download or QSAR

Found 450 hits with Last Name = 'haydar' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308167 ((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303164 (1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H23N3O3S/c1-16(27)19-11-12-20-23(24-19)22(15-26(20)14-13-25(2)3)30(28,29)21-10-6-8-17-7-4-5-9-18(17)21/h4-12,15H,13-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308181 ((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308183 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...) Show SMILES NC1CN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C20H18N4O2S/c21-14-11-24(12-14)15-8-9-18-17(10-15)20(23-22-18)27(25,26)19-7-3-5-13-4-1-2-6-16(13)19/h1-10,14H,11-12,21H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308177 (1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES Cc1ccc(c2ccccc12)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C23H24N4O2S/c1-15-6-9-22(19-5-3-2-4-18(15)19)30(28,29)23-20-14-17(7-8-21(20)25-26-23)27-12-10-16(24)11-13-27/h2-9,14,16H,10-13,24H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303163 (1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)e...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C19H20BrN3O3S/c1-13(24)16-8-9-17-19(21-16)18(12-23(17)11-10-22(2)3)27(25,26)15-6-4-14(20)5-7-15/h4-9,12H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308175 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c23-16-10-12-26(13-11-16)17-8-9-20-19(14-17)22(25-24-20)29(27,28)21-7-3-5-15-4-1-2-6-18(15)21/h1-9,14,16H,10-13,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308178 (1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2c(Cl)cccc12 Show InChI InChI=1S/C22H21ClN4O2S/c23-19-5-1-4-17-16(19)3-2-6-21(17)30(28,29)22-18-13-15(7-8-20(18)25-26-22)27-11-9-14(24)10-12-27/h1-8,13-14H,9-12,24H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300828 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308179 (1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H19ClN4O2S/c19-12-2-1-3-15(10-12)26(24,25)18-16-11-14(4-5-17(16)21-22-18)23-8-6-13(20)7-9-23/h1-5,10-11,13H,6-9,20H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303162 (1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsul...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C19H20FN3O3S/c1-13(24)16-7-8-17-19(21-16)18(12-23(17)10-9-22(2)3)27(25,26)15-6-4-5-14(20)11-15/h4-8,11-12H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308180 (1-{3-[(4-Isopropylphenyl)sulfonyl]-1H-indazol-5-yl...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C21H26N4O2S/c1-14(2)15-3-6-18(7-4-15)28(26,27)21-19-13-17(5-8-20(19)23-24-21)25-11-9-16(22)10-12-25/h3-8,13-14,16H,9-12,22H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308170 ((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-22-11-10-19(27-13-12-18(25)15-27)14-21(22)24(26-28)31(29,30)23-9-5-7-17-6-3-4-8-20(17)23/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308176 (1-[3-(2-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H22N4O2S/c23-17-9-11-26(12-10-17)18-6-8-21-20(14-18)22(25-24-21)29(27,28)19-7-5-15-3-1-2-4-16(15)13-19/h1-8,13-14,17H,9-12,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308181 ((3S)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308169 ((3R)-1-[1-Methyl-3-(naphthalen-1-ylsulfonyl)-1H-in...) Show SMILES Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-12-11-16(23)14-26)13-19(20)22(24-25)29(27,28)21-8-4-6-15-5-2-3-7-18(15)21/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300832 (CHEMBL578826 | N,N-Dimethyl-N-{2-[3-(phenylsulfony...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H19N3O2S/c1-19(2)11-12-20-13-16(15-9-6-10-18-17(15)20)23(21,22)14-7-4-3-5-8-14/h3-10,13H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308168 ((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303166 (2-(3-(3-chlorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H14ClN3O2S/c16-11-3-1-4-12(9-11)22(20,21)14-10-19(8-6-17)13-5-2-7-18-15(13)14/h1-5,7,9-10H,6,8,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308171 ((3R)-1-[1-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-23-11-10-20(28-13-12-19(26)16-28)14-22(23)25(27-29)32(30,31)24-9-5-7-18-6-3-4-8-21(18)24/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303168 (2-(3-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C14H12ClN5O2S2/c15-12-13(20-6-7-23-14(20)18-12)24(21,22)10-8-19(5-3-16)9-2-1-4-17-11(9)10/h1-2,4,6-8H,3,5,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50319673 (1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...) Show SMILES Fc1ccc(cc1)-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 Show InChI InChI=1S/C21H27FN4O/c22-18-8-6-17(7-9-18)20-11-10-19(16-24-20)25-21(27)23-12-2-5-15-26-13-3-1-4-14-26/h6-11,16H,1-5,12-15H2,(H2,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303167 (2-(3-(m-tolylsulfonyl)-1H-pyrrolo[3,2-b]pyridin-1-...) Show SMILES Cc1cccc(c1)S(=O)(=O)c1cn(CCN)c2cccnc12 Show InChI InChI=1S/C16H17N3O2S/c1-12-4-2-5-13(10-12)22(20,21)15-11-19(9-7-17)14-6-3-8-18-16(14)15/h2-6,8,10-11H,7,9,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308173 ((3R)-1-[2-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-24(31(29,30)23-9-5-7-17-6-3-4-8-20(17)23)21-14-19(10-11-22(21)26-28)27-13-12-18(25)15-27/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308172 ((3R)-1-[2-Methyl-3-(naphthalen-1-ylsulfonyl)-2H-in...) Show SMILES Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-22(29(27,28)21-8-4-6-15-5-2-3-7-18(15)21)19-13-17(9-10-20(19)24-25)26-12-11-16(23)14-26/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	54.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303161 (1-(1-(2-(dimethylamino)ethyl)-3-(phenylsulfonyl)-1...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H21N3O3S/c1-14(23)16-9-10-17-19(20-16)18(13-22(17)12-11-21(2)3)26(24,25)15-7-5-4-6-8-15/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50308174 ((3R)-1-[2-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-25(32(30,31)24-9-5-7-18-6-3-4-8-21(18)24)22-14-20(10-11-23(22)27-29)28-13-12-19(26)16-28/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303165 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES NCCn1cc(c2ncccc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C15H14FN3O2S/c16-11-3-1-4-12(9-11)22(20,21)14-10-19(8-6-17)13-5-2-7-18-15(13)14/h1-5,7,9-10H,6,8,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308178 (1-{3-[(5-Chloro-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2c(Cl)cccc12 Show InChI InChI=1S/C22H21ClN4O2S/c23-19-5-1-4-17-16(19)3-2-6-21(17)30(28,29)22-18-13-15(7-8-20(18)25-26-22)27-11-9-14(24)10-12-27/h1-8,13-14H,9-12,24H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308183 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...) Show SMILES NC1CN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C20H18N4O2S/c21-14-11-24(12-14)15-8-9-18-17(10-15)20(23-22-18)27(25,26)19-7-3-5-13-4-1-2-6-16(13)19/h1-10,14H,11-12,21H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308175 (1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c23-16-10-12-26(13-11-16)17-8-9-20-19(14-17)22(25-24-20)29(27,28)21-7-3-5-15-4-1-2-6-18(15)21/h1-9,14,16H,10-13,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308169 ((3R)-1-[1-Methyl-3-(naphthalen-1-ylsulfonyl)-1H-in...) Show SMILES Cn1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-12-11-16(23)14-26)13-19(20)22(24-25)29(27,28)21-8-4-6-15-5-2-3-7-18(15)21/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308170 ((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H26N4O2S/c1-16(2)28-22-11-10-19(27-13-12-18(25)15-27)14-21(22)24(26-28)31(29,30)23-9-5-7-17-6-3-4-8-20(17)23/h3-11,14,16,18H,12-13,15,25H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303159 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[3,2-b]pyr...) Show SMILES CN(C)CCn1cc(c2ncccc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(17-15(21)7-4-8-19-17)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303160 (2-(5-chloro-3-(phenylsulfonyl)-1H-pyrrolo[3,2-b]py...) Show SMILES CN(C)CCn1cc(c2nc(Cl)ccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18ClN3O2S/c1-20(2)10-11-21-12-15(17-14(21)8-9-16(18)19-17)24(22,23)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308174 ((3R)-1-[2-(2-Methylpropyl)-3-(naphthalen-1-ylsulfo...) Show SMILES CC(C)Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H28N4O2S/c1-17(2)15-29-25(32(30,31)24-9-5-7-18-6-3-4-8-21(18)24)22-14-20(10-11-23(22)27-29)28-13-12-19(26)16-28/h3-11,14,17,19H,12-13,15-16,26H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50300802 (5-Morpholin-4-ylpentanoic acid(4-pyridin-3-ylpheny...) Show SMILES O=C(CCCCN1CCOCC1)Nc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C20H25N3O2/c24-20(5-1-2-11-23-12-14-25-15-13-23)22-19-8-6-17(7-9-19)18-4-3-10-21-16-18/h3-4,6-10,16H,1-2,5,11-15H2,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat rat alpha7 nAChR expressed in rat GH4C1 cells				Bioorg Med Chem 17: 5247-58 (2009) Article DOI: 10.1016/j.bmc.2009.05.040 BindingDB Entry DOI: 10.7270/Q29K4B8H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	274	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303158 (CHEMBL576312 | N,N-dimethyl-2-(3-(phenylsulfonyl)-...) Show SMILES CN(C)CCn1cc(c2ncccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H19N3O2S/c1-19(2)11-12-20-13-16(17-15(20)9-6-10-18-17)23(21,22)14-7-4-3-5-8-14/h3-10,13H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399292 (CHEMBL2180842) Show SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1 Show InChI InChI=1S/C17H22FN5O/c18-14-9-13(11-19-12-14)15-10-16(22-21-15)20-17(24)5-4-8-23-6-2-1-3-7-23/h9-12H,1-8H2,(H2,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranes				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308167 ((3R)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	423	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308179 (1-(3-(3-chlorophenylsulfonyl)-1H-indazol-5-yl)pipe...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H19ClN4O2S/c19-12-2-1-3-15(10-12)26(24,25)18-16-11-14(4-5-17(16)21-22-18)23-8-6-13(20)7-9-23/h1-5,10-11,13H,6-9,20H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	442	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308172 ((3R)-1-[2-Methyl-3-(naphthalen-1-ylsulfonyl)-2H-in...) Show SMILES Cn1nc2ccc(cc2c1S(=O)(=O)c1cccc2ccccc12)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C22H22N4O2S/c1-25-22(29(27,28)21-8-4-6-15-5-2-3-7-18(15)21)19-13-17(9-10-20(19)24-25)26-12-11-16(23)14-26/h2-10,13,16H,11-12,14,23H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	455	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308177 (1-{3-[(4-Methyl-1-naphthyl)sulfonyl]-1H-indazol-5-...) Show SMILES Cc1ccc(c2ccccc12)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCC(N)CC1 Show InChI InChI=1S/C23H24N4O2S/c1-15-6-9-22(19-5-3-2-4-18(15)19)30(28,29)23-20-14-17(7-8-21(20)25-26-23)27-12-10-16(24)11-13-27/h2-9,14,16H,10-13,24H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	493	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308168 ((3S)-N,N-Dimethyl-1-[3-(1-naphthylsulfonyl)-1H-ind...) Show SMILES CN(C)[C@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H24N4O2S/c1-26(2)18-12-13-27(15-18)17-10-11-21-20(14-17)23(25-24-21)30(28,29)22-9-5-7-16-6-3-4-8-19(16)22/h3-11,14,18H,12-13,15H2,1-2H3,(H,24,25)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399293 (CHEMBL2086582) Show SMILES COc1ccc(cc1)-c1cc(NC(=O)CCCCN2CCCN(CC2)C(C)=O)[nH]n1 Show InChI InChI=1S/C22H31N5O3/c1-17(28)27-13-5-12-26(14-15-27)11-4-3-6-22(29)23-21-16-20(24-25-21)18-7-9-19(30-2)10-8-18/h7-10,16H,3-6,11-15H2,1-2H3,(H2,23,24,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in GH4C1 cells after 1 hr by TopCount method				J Med Chem 55: 4806-23 (2012) Article DOI: 10.1021/jm300247y BindingDB Entry DOI: 10.7270/Q2VM4DJ7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50308176 (1-[3-(2-Naphthylsulfonyl)-1H-indazol-5-yl]piperidi...) Show SMILES NC1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H22N4O2S/c23-17-9-11-26(12-10-17)18-6-8-21-20(14-18)22(25-24-21)29(27,28)19-7-5-15-3-1-2-4-16(15)13-19/h1-8,13-14,17H,9-12,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation counting				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to 5HT1D receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50308182 ((3R)-1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]pyr...) Show SMILES N[C@@H]1CCN(C1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C21H20N4O2S/c22-15-10-11-25(13-15)16-8-9-19-18(12-16)21(24-23-19)28(26,27)20-7-3-5-14-4-1-2-6-17(14)20/h1-9,12,15H,10-11,13,22H2,(H,23,24)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to dopamine D2 receptor				J Med Chem 53: 2521-7 (2010) Article DOI: 10.1021/jm901674f BindingDB Entry DOI: 10.7270/Q22B8Z43
					More data for this Ligand-Target Pair

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