Compile Data Set for Download or QSAR

Found 405 hits with Last Name = 'hernandez' and Initial = 'le'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152472 (CHEMBL182261 | N-[3-(2-Amino-quinolin-8-yloxy)-pro...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)c3cccc(Cl)c3)c2n1 Show InChI InChI=1S/C19H18ClN3O2/c20-15-6-1-5-14(12-15)19(24)22-10-3-11-25-16-7-2-4-13-8-9-17(21)23-18(13)16/h1-2,4-9,12H,3,10-11H2,(H2,21,23)(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152494 (8-[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-pyrrolid...) Show SMILES Nc1ccc2cccc(OC3CCN(C3)c3ccc4OC(F)(F)Oc4c3)c2n1 Show InChI InChI=1S/C20H17F2N3O3/c21-20(22)27-15-6-5-13(10-17(15)28-20)25-9-8-14(11-25)26-16-3-1-2-12-4-7-18(23)24-19(12)16/h1-7,10,14H,8-9,11H2,(H2,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152479 (1-[3-(2-Amino-quinolin-8-yloxy)-propyl]-3-(3-chlor...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)Nc3cccc(Cl)c3)c2n1 Show InChI InChI=1S/C19H19ClN4O2/c20-14-5-2-6-15(12-14)23-19(25)22-10-3-11-26-16-7-1-4-13-8-9-17(21)24-18(13)16/h1-2,4-9,12H,3,10-11H2,(H2,21,24)(H2,22,23,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152463 (8-[3-(2,2-Difluoro-benzo[1,3]dioxol-5-ylamino)-pro...) Show SMILES Nc1ccc2cccc(OCCCNc3ccc4OC(F)(F)Oc4c3)c2n1 Show InChI InChI=1S/C19H17F2N3O3/c20-19(21)26-14-7-6-13(11-16(14)27-19)23-9-2-10-25-15-4-1-3-12-5-8-17(22)24-18(12)15/h1,3-8,11,23H,2,9-10H2,(H2,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152495 (8-[(S)-1-(4-tert-Butyl-benzyl)-pyrrolidin-3-yloxy]...) Show SMILES CC(C)(C)c1ccc(CN2CC[C@@H](C2)Oc2cccc3ccc(N)nc23)cc1 Show InChI InChI=1S/C24H29N3O/c1-24(2,3)19-10-7-17(8-11-19)15-27-14-13-20(16-27)28-21-6-4-5-18-9-12-22(25)26-23(18)21/h4-12,20H,13-16H2,1-3H3,(H2,25,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152486 (3-Chloro-N-[3-(2-{[5-(2-chloro-phenyl)-furan-2-ylm...) Show SMILES Clc1cccc(c1)C(=O)NCCCOc1cccc2ccc(NCc3ccc(o3)-c3ccccc3Cl)nc12 Show InChI InChI=1S/C30H25Cl2N3O3/c31-22-8-3-7-21(18-22)30(36)33-16-5-17-37-27-11-4-6-20-12-15-28(35-29(20)27)34-19-23-13-14-26(38-23)24-9-1-2-10-25(24)32/h1-4,6-15,18H,5,16-17,19H2,(H,33,36)(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152481 (8-[2-(3-Methoxy-benzylamino)-1-methyl-ethoxy]-quin...) Show SMILES COc1cccc(CNCC(C)Oc2cccc3ccc(N)nc23)c1 Show InChI InChI=1S/C20H23N3O2/c1-14(12-22-13-15-5-3-7-17(11-15)24-2)25-18-8-4-6-16-9-10-19(21)23-20(16)18/h3-11,14,22H,12-13H2,1-2H3,(H2,21,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152497 (8-[1-(4-Isobutyl-phenyl)-pyrrolidin-3-yloxy]-quino...) Show SMILES CC(C)Cc1ccc(cc1)N1CCC(C1)Oc1cccc2ccc(N)nc12 Show InChI InChI=1S/C23H27N3O/c1-16(2)14-17-6-9-19(10-7-17)26-13-12-20(15-26)27-21-5-3-4-18-8-11-22(24)25-23(18)21/h3-11,16,20H,12-15H2,1-2H3,(H2,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50162116 (2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...) Show SMILES O=C(Cc1ccc(OCc2ccccc2)cc1)Nc1ccc2cnn(CCN3CCCC3)c2c1 Show InChI InChI=1S/C28H30N4O2/c33-28(18-22-8-12-26(13-9-22)34-21-23-6-2-1-3-7-23)30-25-11-10-24-20-29-32(27(24)19-25)17-16-31-14-4-5-15-31/h1-3,6-13,19-20H,4-5,14-18,21H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inihibition of melanin concentrating hormone receptor 1 from human neuronal IMR-32 cells				J Med Chem 48: 1318-21 (2005) Article DOI: 10.1021/jm0490890 BindingDB Entry DOI: 10.7270/Q2794459
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50162116 (2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...) Show SMILES O=C(Cc1ccc(OCc2ccccc2)cc1)Nc1ccc2cnn(CCN3CCCC3)c2c1 Show InChI InChI=1S/C28H30N4O2/c33-28(18-22-8-12-26(13-9-22)34-21-23-6-2-1-3-7-23)30-25-11-10-24-20-29-32(27(24)19-25)17-16-31-14-4-5-15-31/h1-3,6-13,19-20H,4-5,14-18,21H2,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against Melanin-concentrating hormone receptor 1 in diet-induced obese mice				Bioorg Med Chem Lett 15: 2752-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.114 BindingDB Entry DOI: 10.7270/Q2QJ7GSD
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50167565 (1-[1-(2-Isobutylamino-ethyl)-1H-indazol-5-yl]-3-(4...) Show SMILES CC(C)CNCCn1ncc2cc(NC(=O)Nc3ccc(Oc4ccccc4)cc3)ccc12 Show InChI InChI=1S/C26H29N5O2/c1-19(2)17-27-14-15-31-25-13-10-22(16-20(25)18-28-31)30-26(32)29-21-8-11-24(12-9-21)33-23-6-4-3-5-7-23/h3-13,16,18-19,27H,14-15,17H2,1-2H3,(H2,29,30,32)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				Bioorg Med Chem Lett 15: 2752-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.114 BindingDB Entry DOI: 10.7270/Q2QJ7GSD
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207679 (CHEMBL246258 | N-(1-(2-chloro-4-((2-(pyrrolidin-1-...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(cc2Cl)C(=O)NCCN2CCCC2)CC1 Show InChI InChI=1S/C29H32ClFN4O4/c30-24-15-19(28(37)32-9-14-34-10-1-2-11-34)3-4-20(24)18-35-12-7-22(8-13-35)33-29(38)27-17-25(36)23-6-5-21(31)16-26(23)39-27/h3-6,15-17,22H,1-2,7-14,18H2,(H,32,37)(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152469 (CHEMBL182575 | N-[3-(2-{[5-(4-Chloro-phenyl)-furan...) Show SMILES Clc1ccc(cc1)-c1ccc(CNc2ccc3cccc(OCCCNC(=O)c4cccc(c4)C#N)c3n2)o1 Show InChI InChI=1S/C31H25ClN4O3/c32-25-11-8-22(9-12-25)27-14-13-26(39-27)20-35-29-15-10-23-5-2-7-28(30(23)36-29)38-17-3-16-34-31(37)24-6-1-4-21(18-24)19-33/h1-2,4-15,18H,3,16-17,20H2,(H,34,37)(H,35,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152480 (CHEMBL184243 | N-[3-(2-Amino-quinolin-8-yloxy)-pro...) Show SMILES COc1cccc(c1)C(=O)NCCCOc1cccc2ccc(N)nc12 Show InChI InChI=1S/C20H21N3O3/c1-25-16-7-2-6-15(13-16)20(24)22-11-4-12-26-17-8-3-5-14-9-10-18(21)23-19(14)17/h2-3,5-10,13H,4,11-12H2,1H3,(H2,21,23)(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171590 (CHEMBL194697 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1ccc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C24H25ClN4O3S/c25-17-2-3-20(27-13-23-26-7-10-33-23)19(12-17)24(30)28-18-5-8-29(9-6-18)14-16-1-4-21-22(11-16)32-15-31-21/h1-4,7,10-12,18,27H,5-6,8-9,13-15H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152502 (8-[1-(2-Benzo[1,3]dioxol-5-yl-1-methyl-ethyl)-pyrr...) Show SMILES CC(Cc1ccc2OCOc2c1)N1CCC(C1)Oc1cccc2ccc(N)nc12 Show InChI InChI=1S/C23H25N3O3/c1-15(11-16-5-7-19-21(12-16)28-14-27-19)26-10-9-18(13-26)29-20-4-2-3-17-6-8-22(24)25-23(17)20/h2-8,12,15,18H,9-11,13-14H2,1H3,(H2,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50167552 (1-[1-(2-Cyclopentylamino-ethyl)-1H-indazol-5-yl]-3...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2n(CCNC3CCCC3)ncc2c1 Show InChI InChI=1S/C27H29N5O2/c33-27(30-22-10-13-25(14-11-22)34-24-8-2-1-3-9-24)31-23-12-15-26-20(18-23)19-29-32(26)17-16-28-21-6-4-5-7-21/h1-3,8-15,18-19,21,28H,4-7,16-17H2,(H2,30,31,33)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				Bioorg Med Chem Lett 15: 2752-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.114 BindingDB Entry DOI: 10.7270/Q2QJ7GSD
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152488 (8-[1-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-pyrrolidi...) Show SMILES Nc1ccc2cccc(OC3CCN(C3)c3ccc4OCCOc4c3)c2n1 Show InChI InChI=1S/C21H21N3O3/c22-20-7-4-14-2-1-3-18(21(14)23-20)27-16-8-9-24(13-16)15-5-6-17-19(12-15)26-11-10-25-17/h1-7,12,16H,8-11,13H2,(H2,22,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50197139 (CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H21FN2O5/c24-15-2-3-17-18(27)11-22(31-20(17)10-15)23(28)25-16-5-7-26(8-6-16)12-14-1-4-19-21(9-14)30-13-29-19/h1-4,9-11,16H,5-8,12-13H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50201274 (CHEMBL215661 | N-(1-(6-acetamido-2,3-dihydro-1H-in...) Show SMILES CC(=O)Nc1ccc2CCC(N3CCC(CC3)NC(=O)c3cc(=O)c4ccc(F)cc4o3)c2c1 Show InChI InChI=1S/C26H26FN3O4/c1-15(31)28-19-5-2-16-3-7-22(21(16)13-19)30-10-8-18(9-11-30)29-26(33)25-14-23(32)20-6-4-17(27)12-24(20)34-25/h2,4-6,12-14,18,22H,3,7-11H2,1H3,(H,28,31)(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 884-9 (2007) Article DOI: 10.1016/j.bmcl.2006.11.061 BindingDB Entry DOI: 10.7270/Q2J38S6V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207681 (CHEMBL248297 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(OCCCN3CCCCC3)c(F)c2)CC1 Show InChI InChI=1S/C30H35F2N3O4/c31-22-6-7-24-26(36)19-29(39-28(24)18-22)30(37)33-23-9-14-35(15-10-23)20-21-5-8-27(25(32)17-21)38-16-4-13-34-11-2-1-3-12-34/h5-8,17-19,23H,1-4,9-16,20H2,(H,33,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152472 (CHEMBL182261 | N-[3-(2-Amino-quinolin-8-yloxy)-pro...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)c3cccc(Cl)c3)c2n1 Show InChI InChI=1S/C19H18ClN3O2/c20-15-6-1-5-14(12-15)19(24)22-10-3-11-25-16-7-2-4-13-8-9-17(21)23-18(13)16/h1-2,4-9,12H,3,10-11H2,(H2,21,23)(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50201274 (CHEMBL215661 | N-(1-(6-acetamido-2,3-dihydro-1H-in...) Show SMILES CC(=O)Nc1ccc2CCC(N3CCC(CC3)NC(=O)c3cc(=O)c4ccc(F)cc4o3)c2c1 Show InChI InChI=1S/C26H26FN3O4/c1-15(31)28-19-5-2-16-3-7-22(21(16)13-19)30-10-8-18(9-11-30)29-26(33)25-14-23(32)20-6-4-17(27)12-24(20)34-25/h2,4-6,12-14,18,22H,3,7-11H2,1H3,(H,28,31)(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 884-9 (2007) Article DOI: 10.1016/j.bmcl.2006.11.061 BindingDB Entry DOI: 10.7270/Q2J38S6V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152456 ((S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]...) Show SMILES COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC |t:3| Show InChI InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152478 (CHEMBL184581 | N-[3-(2-Amino-quinolin-8-yloxy)-pro...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)c3cccc(c3)C#N)c2n1 Show InChI InChI=1S/C20H18N4O2/c21-13-14-4-1-6-16(12-14)20(25)23-10-3-11-26-17-7-2-5-15-8-9-18(22)24-19(15)17/h1-2,4-9,12H,3,10-11H2,(H2,22,24)(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50168509 (CHEMBL188937 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1cc(cc(OC)c1C)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1 Show InChI InChI=1S/C23H28N2O5/c1-15-20(27-2)10-17(11-21(15)28-3)23(26)24-18-5-4-8-25(13-18)12-16-6-7-19-22(9-16)30-14-29-19/h6-7,9-11,18H,4-5,8,12-14H2,1-3H3,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration required for binding affinity against mouse MCHr1 competing human neuronal IMR32 cells receptor in a radiometric binding ass...				Bioorg Med Chem Lett 15: 3412-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.023 BindingDB Entry DOI: 10.7270/Q26D5SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50197113 (CHEMBL214731 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Fc1ccc2oc(cc(=O)c2c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H21FN2O5/c24-15-2-4-19-17(10-15)18(27)11-22(31-19)23(28)25-16-5-7-26(8-6-16)12-14-1-3-20-21(9-14)30-13-29-20/h1-4,9-11,16H,5-8,12-13H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 884-9 (2007) Article DOI: 10.1016/j.bmcl.2006.11.061 BindingDB Entry DOI: 10.7270/Q2J38S6V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171580 (CHEMBL196277 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2cscn2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H24ClN5O3S/c24-16-8-19(22(25-9-16)26-10-18-12-33-13-27-18)23(30)28-17-3-5-29(6-4-17)11-15-1-2-20-21(7-15)32-14-31-20/h1-2,7-9,12-13,17H,3-6,10-11,14H2,(H,25,26)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207674 (CHEMBL245844 | N-(1-(4-(3-(2,4-dioxothiazolidin-3-...) Show SMILES Oc1csc(=O)n1CCCOc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1F Show InChI InChI=1S/C28H27F2N3O6S/c29-18-3-4-20-22(34)14-25(39-24(20)13-18)27(36)31-19-6-9-32(10-7-19)15-17-2-5-23(21(30)12-17)38-11-1-8-33-26(35)16-40-28(33)37/h2-5,12-14,16,19,35H,1,6-11,15H2,(H,31,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50201273 (CHEMBL214585 | N-(1-(6,7-dihydro-5H-indeno[5,6-d][...) Show SMILES Fc1ccc2oc(cc(=O)c2c1)C(=O)NC1CCN(CC1)C1CCc2cc3OCOc3cc12 Show InChI InChI=1S/C25H23FN2O5/c26-15-2-4-21-18(10-15)20(29)12-24(33-21)25(30)27-16-5-7-28(8-6-16)19-3-1-14-9-22-23(11-17(14)19)32-13-31-22/h2,4,9-12,16,19H,1,3,5-8,13H2,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 884-9 (2007) Article DOI: 10.1016/j.bmcl.2006.11.061 BindingDB Entry DOI: 10.7270/Q2J38S6V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174908 (CHEMBL427367 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES [O-][N+](=O)c1ccc2n(Cc3ccccc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C27H27N5O4/c33-32(34)22-7-8-24-23(15-22)27(29-31(24)17-19-4-2-1-3-5-19)28-21-10-12-30(13-11-21)16-20-6-9-25-26(14-20)36-18-35-25/h1-9,14-15,21H,10-13,16-18H2,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50201273 (CHEMBL214585 | N-(1-(6,7-dihydro-5H-indeno[5,6-d][...) Show SMILES Fc1ccc2oc(cc(=O)c2c1)C(=O)NC1CCN(CC1)C1CCc2cc3OCOc3cc12 Show InChI InChI=1S/C25H23FN2O5/c26-15-2-4-21-18(10-15)20(29)12-24(33-21)25(30)27-16-5-7-28(8-6-16)19-3-1-14-9-22-23(11-17(14)19)32-13-31-22/h2,4,9-12,16,19H,1,3,5-8,13H2,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 884-9 (2007) Article DOI: 10.1016/j.bmcl.2006.11.061 BindingDB Entry DOI: 10.7270/Q2J38S6V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152455 (8-[3-(4-Chloro-3-trifluoromethyl-benzylamino)-prop...) Show SMILES Nc1ccc2cccc(OCCCNCc3ccc(Cl)c(c3)C(F)(F)F)c2n1 Show InChI InChI=1S/C20H19ClF3N3O/c21-16-7-5-13(11-15(16)20(22,23)24)12-26-9-2-10-28-17-4-1-3-14-6-8-18(25)27-19(14)17/h1,3-8,11,26H,2,9-10,12H2,(H2,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152458 (1-[3-(2-Amino-quinolin-8-yloxy)-propyl]-3-benzo[1,...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)Nc3ccc4OCOc4c3)c2n1 Show InChI InChI=1S/C20H20N4O4/c21-18-8-5-13-3-1-4-16(19(13)24-18)26-10-2-9-22-20(25)23-14-6-7-15-17(11-14)28-12-27-15/h1,3-8,11H,2,9-10,12H2,(H2,21,24)(H2,22,23,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152471 (CHEMBL363464 | N-[3-(2-{[5-(3-Chloro-phenyl)-furan...) Show SMILES Clc1cccc(c1)-c1ccc(CNc2ccc3cccc(OCCCNC(=O)c4cccc(c4)C#N)c3n2)o1 Show InChI InChI=1S/C31H25ClN4O3/c32-25-9-2-7-23(18-25)27-13-12-26(39-27)20-35-29-14-11-22-6-3-10-28(30(22)36-29)38-16-4-15-34-31(37)24-8-1-5-21(17-24)19-33/h1-3,5-14,17-18H,4,15-16,20H2,(H,34,37)(H,35,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152455 (8-[3-(4-Chloro-3-trifluoromethyl-benzylamino)-prop...) Show SMILES Nc1ccc2cccc(OCCCNCc3ccc(Cl)c(c3)C(F)(F)F)c2n1 Show InChI InChI=1S/C20H19ClF3N3O/c21-16-7-5-13(11-15(16)20(22,23)24)12-26-9-2-10-28-17-4-1-3-14-6-8-18(25)27-19(14)17/h1,3-8,11,26H,2,9-10,12H2,(H2,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4883-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.035 BindingDB Entry DOI: 10.7270/Q2GB23H4
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50167554 (1-(4-Phenoxy-phenyl)-3-[1-(2-pyrrolidin-1-yl-ethyl...) Show SMILES O=c1n(ccn1-c1ccc2n(CCN3CCCC3)ncc2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H27N5O2/c34-28-31(23-8-11-26(12-9-23)35-25-6-2-1-3-7-25)17-18-32(28)24-10-13-27-22(20-24)21-29-33(27)19-16-30-14-4-5-15-30/h1-3,6-13,17-18,20-21H,4-5,14-16,19H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				Bioorg Med Chem Lett 15: 2752-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.114 BindingDB Entry DOI: 10.7270/Q2QJ7GSD
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171577 (CHEMBL196681 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H24ClN5O3S/c24-16-10-18(22(26-11-16)27-12-21-25-5-8-33-21)23(30)28-17-3-6-29(7-4-17)13-15-1-2-19-20(9-15)32-14-31-19/h1-2,5,8-11,17H,3-4,6-7,12-14H2,(H,26,27)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152470 (CHEMBL364210 | N-[3-(2-Amino-quinolin-8-yloxy)-pro...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)c3cccc(OC(F)(F)F)c3)c2n1 Show InChI InChI=1S/C20H18F3N3O3/c21-20(22,23)29-15-6-1-5-14(12-15)19(27)25-10-3-11-28-16-7-2-4-13-8-9-17(24)26-18(13)16/h1-2,4-9,12H,3,10-11H2,(H2,24,26)(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171597 (5-Chloro-N-(1-naphthalen-2-ylmethyl-piperidin-4-yl...) Show SMILES Clc1ccc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H27ClN4OS/c28-22-7-8-25(30-17-26-29-11-14-34-26)24(16-22)27(33)31-23-9-12-32(13-10-23)18-19-5-6-20-3-1-2-4-21(20)15-19/h1-8,11,14-16,23,30H,9-10,12-13,17-18H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174921 (CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C20H21N5O4/c26-25(27)15-2-3-17-16(10-15)20(23-22-17)21-14-5-7-24(8-6-14)11-13-1-4-18-19(9-13)29-12-28-18/h1-4,9-10,14H,5-8,11-12H2,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171594 (CHEMBL196223 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES CC(C)OCCCNc1ncc(Cl)cc1C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C25H33ClN4O4/c1-17(2)32-11-3-8-27-24-21(13-19(26)14-28-24)25(31)29-20-6-9-30(10-7-20)15-18-4-5-22-23(12-18)34-16-33-22/h4-5,12-14,17,20H,3,6-11,15-16H2,1-2H3,(H,27,28)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152454 (Benzo[1,3]dioxole-5-carboxylic acid [3-(2-amino-qu...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)c3ccc4OCOc4c3)c2n1 Show InChI InChI=1S/C20H19N3O4/c21-18-8-6-13-3-1-4-16(19(13)23-18)25-10-2-9-22-20(24)14-5-7-15-17(11-14)27-12-26-15/h1,3-8,11H,2,9-10,12H2,(H2,21,23)(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174920 (CHEMBL199025 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Clc1ccc2n(Cc3ccncc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C26H26ClN5O2/c27-20-2-3-23-22(14-20)26(30-32(23)16-18-5-9-28-10-6-18)29-21-7-11-31(12-8-21)15-19-1-4-24-25(13-19)34-17-33-24/h1-6,9-10,13-14,21H,7-8,11-12,15-17H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174919 (CHEMBL371222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES COc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C21H24N4O3/c1-26-16-3-4-18-17(11-16)21(24-23-18)22-15-6-8-25(9-7-15)12-14-2-5-19-20(10-14)28-13-27-19/h2-5,10-11,15H,6-9,12-13H2,1H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171580 (CHEMBL196277 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2cscn2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H24ClN5O3S/c24-16-8-19(22(25-9-16)26-10-18-12-33-13-27-18)23(30)28-17-3-5-29(6-4-17)11-15-1-2-20-21(7-15)32-14-31-20/h1-2,7-9,12-13,17H,3-6,10-11,14H2,(H,25,26)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50167561 (1-[1-(3-Cyclopentylamino-propyl)-1H-indazol-5-yl]-...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2n(CCCNC3CCCC3)ncc2c1 Show InChI InChI=1S/C28H31N5O2/c34-28(31-23-11-14-26(15-12-23)35-25-9-2-1-3-10-25)32-24-13-16-27-21(19-24)20-30-33(27)18-6-17-29-22-7-4-5-8-22/h1-3,9-16,19-20,22,29H,4-8,17-18H2,(H2,31,32,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				Bioorg Med Chem Lett 15: 2752-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.114 BindingDB Entry DOI: 10.7270/Q2QJ7GSD
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171587 (CHEMBL373266 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1ccc(NCc2cncnc2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C26H29N5O4/c1-33-21-3-4-23(29-14-19-12-27-16-28-13-19)22(11-21)26(32)30-20-6-8-31(9-7-20)15-18-2-5-24-25(10-18)35-17-34-24/h2-5,10-13,16,20,29H,6-9,14-15,17H2,1H3,(H,30,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171600 (CHEMBL371700 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H25ClN6O3/c24-16-8-19(22(26-9-16)27-11-18-10-25-13-28-18)23(31)29-17-3-5-30(6-4-17)12-15-1-2-20-21(7-15)33-14-32-20/h1-2,7-10,13,17H,3-6,11-12,14H2,(H,25,28)(H,26,27)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171577 (CHEMBL196681 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES Clc1cnc(NCc2nccs2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H24ClN5O3S/c24-16-10-18(22(26-11-16)27-12-21-25-5-8-33-21)23(30)28-17-3-6-29(7-4-17)13-15-1-2-19-20(9-15)32-14-31-19/h1-2,5,8-11,17H,3-4,6-7,12-14H2,(H,26,27)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair

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