Compile Data Set for Download or QSAR

Found 333 hits with Last Name = 'hertzog' and Initial = 'dl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199266 (6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-2-na...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4cc(CN5CCCCC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C28H24ClN3OS/c29-23-9-6-20(7-10-23)26-16-25-27(34-26)28(33)32(18-30-25)24-11-8-21-14-19(4-5-22(21)15-24)17-31-12-2-1-3-13-31/h4-11,14-16,18H,1-3,12-13,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50241083 (6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199205 (6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-6-...) Show SMILES CN(C)Cc1ccc2cc(ccc2n1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H19ClN4OS/c1-28(2)13-18-8-5-16-11-19(9-10-20(16)27-18)29-14-26-21-12-22(31-23(21)24(29)30)15-3-6-17(25)7-4-15/h3-12,14H,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199251 (6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-7,8-...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4C=C(CN5CCCCC5)CCc4c3)c(=O)c2s1 |t:18| Show InChI InChI=1S/C28H26ClN3OS/c29-23-9-6-20(7-10-23)26-16-25-27(34-26)28(33)32(18-30-25)24-11-8-21-14-19(4-5-22(21)15-24)17-31-12-2-1-3-13-31/h6-11,14-16,18H,1-5,12-13,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199249 (6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-7,8...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4C=C(CN5CCCC5)CCc4c3)c(=O)c2s1 |t:18| Show InChI InChI=1S/C27H24ClN3OS/c28-22-8-5-19(6-9-22)25-15-24-26(33-25)27(32)31(17-29-24)23-10-7-20-13-18(3-4-21(20)14-23)16-30-11-1-2-12-30/h5-10,13-15,17H,1-4,11-12,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199202 (6-(4-chlorophenyl)-3-[2-(1-piperidinylmethyl)-6-qu...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCCCC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C27H23ClN4OS/c28-20-7-4-18(5-8-20)25-15-24-26(34-25)27(33)32(17-29-24)22-10-11-23-19(14-22)6-9-21(30-23)16-31-12-2-1-3-13-31/h4-11,14-15,17H,1-3,12-13,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199254 (6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-1-b...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4sc(CN5CCCC5)cc4c3)c(=O)c2s1 Show InChI InChI=1S/C25H20ClN3OS2/c26-18-5-3-16(4-6-18)23-13-21-24(32-23)25(30)29(15-27-21)19-7-8-22-17(11-19)12-20(31-22)14-28-9-1-2-10-28/h3-8,11-13,15H,1-2,9-10,14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199219 (6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-6-q...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCCC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C26H21ClN4OS/c27-19-6-3-17(4-7-19)24-14-23-25(33-24)26(32)31(16-28-23)21-9-10-22-18(13-21)5-8-20(29-22)15-30-11-1-2-12-30/h3-10,13-14,16H,1-2,11-12,15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422940 (CHEMBL213008) Show SMILES COc1ccc(cc1)-c1cc2ncn(-c3ccc(OCCN4CCCC4)c(OC)c3)c(=O)c2s1 Show InChI InChI=1S/C26H27N3O4S/c1-31-20-8-5-18(6-9-20)24-16-21-25(34-24)26(30)29(17-27-21)19-7-10-22(23(15-19)32-2)33-14-13-28-11-3-4-12-28/h5-10,15-17H,3-4,11-14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199258 (6-(4-chlorophenyl)-3-[1-methyl-2-(pyrrolidin-1-ylm...) Show SMILES Cn1c(CN2CCCC2)cc2cc(ccc12)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H23ClN4OS/c1-29-21(15-30-10-2-3-11-30)13-18-12-20(8-9-23(18)29)31-16-28-22-14-24(33-25(22)26(31)32)17-4-6-19(27)7-5-17/h4-9,12-14,16H,2-3,10-11,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199248 (6-(4-methylphenyl)-3-[2-(pyrrolidin-1-ylmethyl)-1-...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4oc(CN5CCCC5)cc4c3)c(=O)c2s1 Show InChI InChI=1S/C25H20ClN3O2S/c26-18-5-3-16(4-6-18)23-13-21-24(32-23)25(30)29(15-27-21)19-7-8-22-17(11-19)12-20(31-22)14-28-9-1-2-10-28/h3-8,11-13,15H,1-2,9-10,14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199256 (6-(4-chlorophenyl)-3-{6-[(dimethylamino)methyl]-5,...) Show SMILES CN(C)CC1CCc2cc(ccc2C1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN3OS/c1-28(2)14-16-3-4-19-12-21(10-7-18(19)11-16)29-15-27-22-13-23(31-24(22)25(29)30)17-5-8-20(26)9-6-17/h5-10,12-13,15-16H,3-4,11,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199253 (6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-5,6...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4CC(CN5CCCC5)CCc4c3)c(=O)c2s1 Show InChI InChI=1S/C27H26ClN3OS/c28-22-8-5-19(6-9-22)25-15-24-26(33-25)27(32)31(17-29-24)23-10-7-20-13-18(3-4-21(20)14-23)16-30-11-1-2-12-30/h5-10,14-15,17-18H,1-4,11-13,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199229 (6-(4-chlorophenyl)-3-{2-[(4-phenyl-1-piperidinyl)m...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCC(CC5)c5ccccc5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C33H27ClN4OS/c34-26-9-6-24(7-10-26)31-19-30-32(40-31)33(39)38(21-35-30)28-12-13-29-25(18-28)8-11-27(36-29)20-37-16-14-23(15-17-37)22-4-2-1-3-5-22/h1-13,18-19,21,23H,14-17,20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199260 (6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-1-...) Show SMILES CN(C)Cc1cc2cc(ccc2s1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H18ClN3OS2/c1-26(2)12-18-10-15-9-17(7-8-20(15)29-18)27-13-25-19-11-21(30-22(19)23(27)28)14-3-5-16(24)6-4-14/h3-11,13H,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422936 (CHEMBL212657) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C25H24FN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199265 (6-(4-chlorophenyl)-3-(2-{[(2R)-2-(methoxymethyl)py...) Show SMILES COC[C@H]1CCCN1Cc1cc2cc(ccc2n1C)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H27ClN4O2S/c1-31-23(15-32-11-3-4-22(32)16-35-2)13-19-12-21(9-10-25(19)31)33-17-30-24-14-26(36-27(24)28(33)34)18-5-7-20(29)8-6-18/h5-10,12-14,17,22H,3-4,11,15-16H2,1-2H3/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199223 (6-(4-chlorophenyl)-3-[2-({4-[2-(1-pyrrolidinyl)eth...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCC(CCN6CCCC6)CC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C33H34ClN5OS/c34-26-6-3-24(4-7-26)31-20-30-32(41-31)33(40)39(22-35-30)28-9-10-29-25(19-28)5-8-27(36-29)21-38-17-12-23(13-18-38)11-16-37-14-1-2-15-37/h3-10,19-20,22-23H,1-2,11-18,21H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422916 (CHEMBL215643) Show SMILES CN(C)c1nc2ccc(cc2n1C)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H18ClN5OS/c1-26(2)22-25-16-9-8-15(10-18(16)27(22)3)28-12-24-17-11-19(30-20(17)21(28)29)13-4-6-14(23)7-5-13/h4-12H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422927 (CHEMBL441368) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H23Cl2N3O3S/c1-32-22-13-17(5-7-21(22)33-11-10-29-8-2-3-9-29)30-15-28-20-14-23(34-24(20)25(30)31)16-4-6-18(26)19(27)12-16/h4-7,12-15H,2-3,8-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422890 (CHEMBL213813) Show SMILES Cc1nc2cc(ccc2n1CCCO)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H19ClN4O2S/c1-14-26-18-11-17(7-8-20(18)27(14)9-2-10-29)28-13-25-19-12-21(31-22(19)23(28)30)15-3-5-16(24)6-4-15/h3-8,11-13,29H,2,9-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422930 (CHEMBL214276) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccccc1 Show InChI InChI=1S/C25H25N3O3S/c1-30-22-15-19(9-10-21(22)31-14-13-27-11-5-6-12-27)28-17-26-20-16-23(32-24(20)25(28)29)18-7-3-2-4-8-18/h2-4,7-10,15-17H,5-6,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199252 (6-(4-chlorophenyl)-3-[2-(piperidin-1-ylmethyl)-1-b...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4sc(CN5CCCCC5)cc4c3)c(=O)c2s1 Show InChI InChI=1S/C26H22ClN3OS2/c27-19-6-4-17(5-7-19)24-14-22-25(33-24)26(31)30(16-28-22)20-8-9-23-18(12-20)13-21(32-23)15-29-10-2-1-3-11-29/h4-9,12-14,16H,1-3,10-11,15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422893 (CHEMBL384724) Show SMILES Cc1nc2cc(ccc2n1CCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H24ClN5OS/c1-17-29-21-14-20(8-9-23(21)31(17)13-12-30-10-2-3-11-30)32-16-28-22-15-24(34-25(22)26(32)33)18-4-6-19(27)7-5-18/h4-9,14-16H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199214 (6-(4-chlorophenyl)-3-[2-(1H-imidazol-1-ylmethyl)-6...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(Cn5ccnc5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C25H16ClN5OS/c26-18-4-1-16(2-5-18)23-12-22-24(33-23)25(32)31(15-28-22)20-7-8-21-17(11-20)3-6-19(29-21)13-30-10-9-27-14-30/h1-12,14-15H,13H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199206 (6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-3,4...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4OC(CN5CCCC5)CNc4c3)c(=O)c2s1 Show InChI InChI=1S/C25H23ClN4O2S/c26-17-5-3-16(4-6-17)23-12-21-24(33-23)25(31)30(15-28-21)18-7-8-22-20(11-18)27-13-19(32-22)14-29-9-1-2-10-29/h3-8,11-12,15,19,27H,1-2,9-10,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422924 (CHEMBL214416) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H24F3N3O3S/c1-34-22-14-19(8-9-21(22)35-13-12-31-10-2-3-11-31)32-16-30-20-15-23(36-24(20)25(32)33)17-4-6-18(7-5-17)26(27,28)29/h4-9,14-16H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199261 (6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxypyrrolidin...) Show SMILES O[C@@H]1CCN(Cc2cc3cc(ccc3s2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)C1 Show InChI InChI=1S/C25H20ClN3O2S2/c26-17-3-1-15(2-4-17)23-11-21-24(33-23)25(31)29(14-27-21)18-5-6-22-16(9-18)10-20(32-22)13-28-8-7-19(30)12-28/h1-6,9-11,14,19,30H,7-8,12-13H2/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422903 (CHEMBL214716) Show SMILES CN(C)c1nc2ccc(cc2[nH]1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H16ClN5OS/c1-26(2)21-24-15-8-7-14(9-16(15)25-21)27-11-23-17-10-18(29-19(17)20(27)28)12-3-5-13(22)6-4-12/h3-11H,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199262 (6-(4-chlorophenyl)-3-{6-[(dimethylamino)methyl]-7,...) Show SMILES CN(C)CC1=Cc2ccc(cc2CC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 |t:4| Show InChI InChI=1S/C25H22ClN3OS/c1-28(2)14-16-3-4-19-12-21(10-7-18(19)11-16)29-15-27-22-13-23(31-24(22)25(29)30)17-5-8-20(26)9-6-17/h5-13,15H,3-4,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199236 (6-(4-chlorophenyl)-3-{2-[(4-methyl-1-piperazinyl)m...) Show SMILES CN1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H24ClN5OS/c1-31-10-12-32(13-11-31)16-21-7-4-19-14-22(8-9-23(19)30-21)33-17-29-24-15-25(35-26(24)27(33)34)18-2-5-20(28)6-3-18/h2-9,14-15,17H,10-13,16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199257 (6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-5,6,...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4CC(CN5CCCCC5)CCc4c3)c(=O)c2s1 Show InChI InChI=1S/C28H28ClN3OS/c29-23-9-6-20(7-10-23)26-16-25-27(34-26)28(33)32(18-30-25)24-11-8-21-14-19(4-5-22(21)15-24)17-31-12-2-1-3-13-31/h6-11,15-16,18-19H,1-5,12-14,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199240 (6-(4-chlorophenyl)-3-(2-{[4-(4-fluorophenyl)-1-pip...) Show SMILES Fc1ccc(cc1)C1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C33H26ClFN4OS/c34-25-6-1-23(2-7-25)31-18-30-32(41-31)33(40)39(20-36-30)28-11-12-29-24(17-28)5-10-27(37-29)19-38-15-13-22(14-16-38)21-3-8-26(35)9-4-21/h1-12,17-18,20,22H,13-16,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422887 (CHEMBL215868) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc([nH]c4c3)N3CCCC3)c(=O)c2s1 Show InChI InChI=1S/C23H18ClN5OS/c24-15-5-3-14(4-6-15)20-12-19-21(31-20)22(30)29(13-25-19)16-7-8-17-18(11-16)27-23(26-17)28-9-1-2-10-28/h3-8,11-13H,1-2,9-10H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199228 (6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-3,...) Show SMILES CN(C)CC1CNc2cc(ccc2O1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN4O2S/c1-27(2)12-17-11-25-18-9-16(7-8-20(18)30-17)28-13-26-19-10-21(31-22(19)23(28)29)14-3-5-15(24)6-4-14/h3-10,13,17,25H,11-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422896 (CHEMBL214705) Show SMILES CCOc1ccc(cc1)-n1c(C)nc2cc(ccc12)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H21ClN4O2S/c1-3-35-22-11-8-20(9-12-22)33-17(2)31-23-14-21(10-13-25(23)33)32-16-30-24-15-26(36-27(24)28(32)34)18-4-6-19(29)7-5-18/h4-16H,3H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199204 (6-(4-chlorophenyl)-3-{(2R)-2-[(dimethylamino)methy...) Show SMILES CN(C)C[C@@H]1COc2cc(ccc2O1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClN3O3S/c1-26(2)11-17-12-29-20-9-16(7-8-19(20)30-17)27-13-25-18-10-21(31-22(18)23(27)28)14-3-5-15(24)6-4-14/h3-10,13,17H,11-12H2,1-2H3/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422926 (CHEMBL215565) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2nc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN4O3S/c1-31-20-14-18(8-9-19(20)32-13-12-28-10-2-3-11-28)29-15-26-22-21(24(29)30)33-23(27-22)16-4-6-17(25)7-5-16/h4-9,14-15H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199203 (6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxy-1-pyrroli...) Show SMILES O[C@@H]1CCN(CC2CNc3cc(ccc3O2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)C1 Show InChI InChI=1S/C25H23ClN4O3S/c26-16-3-1-15(2-4-16)23-10-21-24(34-23)25(32)30(14-28-21)17-5-6-22-20(9-17)27-11-19(33-22)13-29-8-7-18(31)12-29/h1-6,9-10,14,18-19,27,31H,7-8,11-13H2/t18-,19?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199212 (6-(4-chlorophenyl)-3-[2-(hydroxymethyl)-6-quinolin...) Show SMILES OCc1ccc2cc(ccc2n1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H14ClN3O2S/c23-15-4-1-13(2-5-15)20-10-19-21(29-20)22(28)26(12-24-19)17-7-8-18-14(9-17)3-6-16(11-27)25-18/h1-10,12,27H,11H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199217 (6-(4-chlorophenyl)-3-{2-[(4-methyl-1-piperazinyl)m...) Show SMILES CN1CCN(CC2CNc3cc(ccc3O2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H26ClN5O2S/c1-30-8-10-31(11-9-30)15-20-14-28-21-12-19(6-7-23(21)34-20)32-16-29-22-13-24(35-25(22)26(32)33)17-2-4-18(27)5-3-17/h2-7,12-13,16,20,28H,8-11,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199215 (6-(4-chlorophenyl)-3-{2-[(4-phenyl-1-piperazinyl)m...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCN(CC5)c5ccccc5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C32H26ClN5OS/c33-24-9-6-22(7-10-24)30-19-29-31(40-30)32(39)38(21-34-29)27-12-13-28-23(18-27)8-11-25(35-28)20-36-14-16-37(17-15-36)26-4-2-1-3-5-26/h1-13,18-19,21H,14-17,20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422912 (CHEMBL214476) Show SMILES CNc1nc2ccc(cc2[nH]1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H14ClN5OS/c1-22-20-24-14-7-6-13(8-15(14)25-20)26-10-23-16-9-17(28-18(16)19(26)27)11-2-4-12(21)5-3-11/h2-10H,1H3,(H2,22,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199216 (6-(4-chlorophenyl)-3-[2-(4-morpholinylmethyl)-6-qu...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4nc(CN5CCOCC5)ccc4c3)c(=O)c2s1 Show InChI InChI=1S/C26H21ClN4O2S/c27-19-4-1-17(2-5-19)24-14-23-25(34-24)26(32)31(16-28-23)21-7-8-22-18(13-21)3-6-20(29-22)15-30-9-11-33-12-10-30/h1-8,13-14,16H,9-12,15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7095-107 (2006) Article DOI: 10.1021/jm060572f BindingDB Entry DOI: 10.7270/Q2P26XS8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422900 (CHEMBL215008) Show SMILES COc1ccc(cc1)-n1c(C)nc2cc(ccc12)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H19ClN4O2S/c1-16-30-22-13-20(9-12-24(22)32(16)19-7-10-21(34-2)11-8-19)31-15-29-23-14-25(35-26(23)27(31)33)17-3-5-18(28)6-4-17/h3-15H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422932 (CHEMBL212958) Show SMILES COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C25H24N4O5S/c1-33-22-14-19(8-9-21(22)34-13-12-27-10-2-3-11-27)28-16-26-20-15-23(35-24(20)25(28)30)17-4-6-18(7-5-17)29(31)32/h4-9,14-16H,2-3,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 16: 4723-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.008 BindingDB Entry DOI: 10.7270/Q24B32MB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422918 (CHEMBL384132) Show SMILES CN(CCN1CCCC1)c1nc2ccc(cc2[nH]1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H25ClN6OS/c1-31(12-13-32-10-2-3-11-32)26-29-20-9-8-19(14-21(20)30-26)33-16-28-22-15-23(35-24(22)25(33)34)17-4-6-18(27)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50199263 (6-[6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-...) Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4cc(ccc4c3)C(=O)NCCN3CCCC3)c(=O)c2s1 Show InChI InChI=1S/C29H25ClN4O2S/c30-23-8-5-19(6-9-23)26-17-25-27(37-26)29(36)34(18-32-25)24-10-7-20-15-22(4-3-21(20)16-24)28(35)31-11-14-33-12-1-2-13-33/h3-10,15-18H,1-2,11-14H2,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay				J Med Chem 49: 7108-18 (2006) Article DOI: 10.1021/jm060814b BindingDB Entry DOI: 10.7270/Q2JD4WFT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422886 (CHEMBL385410) Show SMILES CCCn1c(nc2cc(ccc12)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1)N(C)C Show InChI InChI=1S/C24H22ClN5OS/c1-4-11-29-20-10-9-17(12-18(20)27-24(29)28(2)3)30-14-26-19-13-21(32-22(19)23(30)31)15-5-7-16(25)8-6-15/h5-10,12-14H,4,11H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50422892 (CHEMBL214908) Show SMILES CN(C)c1ccc(cc1)-n1c(C)nc2cc(ccc12)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H22ClN5OS/c1-17-31-23-14-22(12-13-25(23)34(17)21-10-8-20(9-11-21)32(2)3)33-16-30-24-15-26(36-27(24)28(33)35)18-4-6-19(29)7-5-18/h4-16H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against MCH1R expressed in CHO cells assessed as inhibition of MCH-induced EC80 thrombin response by luciferase reporter gene ass...				Bioorg Med Chem Lett 16: 4994-5000 (2006) Article DOI: 10.1016/j.bmcl.2006.07.054 BindingDB Entry DOI: 10.7270/Q2833T97
					More data for this Ligand-Target Pair

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