Compile Data Set for Download or QSAR

Found 1486 hits with Last Name = 'hoenke' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127296 (US8791272, 17.1) Show SMILES CCc1nn(C(C)c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C25H26F3N3O3/c1-4-21-20(14-23(32)33)22(5-2)31(30-21)15(3)16-8-12-19(13-9-16)29-24(34)17-6-10-18(11-7-17)25(26,27)28/h6-13,15H,4-5,14H2,1-3H3,(H,29,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197024 (US9206164, 88 | US9206164, 98) Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3cc(ccc3[nH]2)C(C)(C)C)c(CC)c1CC(O)=O Show InChI InChI=1S/C27H31FN4O2/c1-6-21-19(14-25(33)34)24(7-2)32(31-21)15-17-9-8-16(12-20(17)28)26-29-22-11-10-18(27(3,4)5)13-23(22)30-26/h8-13H,6-7,14-15H2,1-5H3,(H,29,30)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50397639 (CHEMBL2181751 | US8791272, 2.47) Show SMILES CCc1c(CC(O)=O)c(nn1Cc1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1)C1CC1 Show InChI InChI=1S/C25H24F3N3O3/c1-2-21-20(13-22(32)33)23(16-5-6-16)30-31(21)14-15-3-11-19(12-4-15)29-24(34)17-7-9-18(10-8-17)25(26,27)28/h3-4,7-12,16H,2,5-6,13-14H2,1H3,(H,29,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127166 (US8791272, 2.42) Show SMILES CCCc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(C(C)C)c1CC(O)=O Show InChI InChI=1S/C29H31N3O3/c1-4-7-26-25(17-27(33)34)28(19(2)3)32(31-26)18-20-10-14-24(15-11-20)30-29(35)23-13-12-21-8-5-6-9-22(21)16-23/h5-6,8-16,19H,4,7,17-18H2,1-3H3,(H,30,35)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127194 (US8791272, 3.12) Show SMILES CCc1nn(Cc2ccc(NC(=O)OCc3ccc4ccccc4c3)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C28H29N3O4/c1-3-25-24(16-27(32)33)26(4-2)31(30-25)17-19-10-13-23(14-11-19)29-28(34)35-18-20-9-12-21-7-5-6-8-22(21)15-20/h5-15H,3-4,16-18H2,1-2H3,(H,29,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127173 (US8791272, 2.50) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(C2CC2)c1CC(O)=O Show InChI InChI=1S/C25H24F3N3O3/c1-2-21-20(13-22(32)33)23(16-5-6-16)31(30-21)14-15-3-11-19(12-4-15)29-24(34)17-7-9-18(10-8-17)25(26,27)28/h3-4,7-12,16H,2,5-6,13-14H2,1H3,(H,29,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196955 (US9206164, 19) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc4ccccc4cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C27H26N4O2/c1-3-22-21(15-26(32)33)25(4-2)31(30-22)16-17-9-11-18(12-10-17)27-28-23-13-19-7-5-6-8-20(19)14-24(23)29-27/h5-14H,3-4,15-16H2,1-2H3,(H,28,29)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127191 (US8791272, 3.9) Show SMILES CCc1nn(Cc2ccc(NC(=O)OCc3ccc(Cl)c(Cl)c3)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H25Cl2N3O4/c1-3-21-18(12-23(30)31)22(4-2)29(28-21)13-15-5-8-17(9-6-15)27-24(32)33-14-16-7-10-19(25)20(26)11-16/h5-11H,3-4,12-14H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127104 (US8791272, 1.15) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)c(C)c1CC(O)=O Show InChI InChI=1S/C25H29N3O3/c1-16-22(14-23(29)30)17(2)28(27-16)15-18-6-12-21(13-7-18)26-24(31)19-8-10-20(11-9-19)25(3,4)5/h6-13H,14-15H2,1-5H3,(H,26,31)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127125 (US8791272, 2.1) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H24F3N3O3/c1-3-20-19(13-22(31)32)21(4-2)30(29-20)14-15-5-11-18(12-6-15)28-23(33)16-7-9-17(10-8-16)24(25,26)27/h5-12H,3-4,13-14H2,1-2H3,(H,28,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127131 (US8791272, 2.14) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C27H27N3O3/c1-3-24-23(16-26(31)32)25(4-2)30(29-24)17-18-9-13-22(14-10-18)28-27(33)21-12-11-19-7-5-6-8-20(19)15-21/h5-15H,3-4,16-17H2,1-2H3,(H,28,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197004 (US9206164, 68) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(C)(C)C)c(CC)c1CC(O)=O Show InChI InChI=1S/C27H32N4O2/c1-6-21-20(15-25(32)33)24(7-2)31(30-21)16-17-8-10-18(11-9-17)26-28-22-13-12-19(27(3,4)5)14-23(22)29-26/h8-14H,6-7,15-16H2,1-5H3,(H,28,29)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127165 (US8791272, 2.41) Show SMILES CCCc1nn(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(C(C)C)c1CC(O)=O Show InChI InChI=1S/C26H28F3N3O3/c1-4-5-22-21(14-23(33)34)24(16(2)3)32(31-22)15-17-6-12-20(13-7-17)30-25(35)18-8-10-19(11-9-18)26(27,28)29/h6-13,16H,4-5,14-15H2,1-3H3,(H,30,35)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127164 (US8791272, 2.40) Show SMILES CCCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C(C)C)c1CC(O)=O Show InChI InChI=1S/C25H27Cl2N3O3/c1-4-5-22-19(13-23(31)32)24(15(2)3)30(29-22)14-16-6-9-18(10-7-16)28-25(33)17-8-11-20(26)21(27)12-17/h6-12,15H,4-5,13-14H2,1-3H3,(H,28,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196956 (US9206164, 20) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(F)(F)F)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H23F3N4O2/c1-3-18-17(12-22(32)33)21(4-2)31(30-18)13-14-5-7-15(8-6-14)23-28-19-10-9-16(24(25,26)27)11-20(19)29-23/h5-11H,3-4,12-13H2,1-2H3,(H,28,29)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127176 (US8791272, 2.53) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(C)c1CC(O)=O Show InChI InChI=1S/C23H22F3N3O3/c1-3-20-19(12-21(30)31)14(2)29(28-20)13-15-4-10-18(11-5-15)27-22(32)16-6-8-17(9-7-16)23(24,25)26/h4-11H,3,12-13H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196952 (US9206164, 16) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc(Cl)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H22Cl2N4O2/c1-3-18-15(9-22(30)31)21(4-2)29(28-18)12-13-5-7-14(8-6-13)23-26-19-10-16(24)17(25)11-20(19)27-23/h5-8,10-11H,3-4,9,12H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127130 (US8791272, 2.6) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H23Cl2N3O3/c1-3-20-17(12-22(29)30)21(4-2)28(27-20)13-14-5-8-16(9-6-14)26-23(31)15-7-10-18(24)19(25)11-15/h5-11H,3-4,12-13H2,1-2H3,(H,26,31)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.25	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127185 (US8791272, 3.3) Show SMILES CCc1nn(Cc2ccc(NC(=O)OCc3ccccc3)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H27N3O4/c1-3-21-20(14-23(28)29)22(4-2)27(26-21)15-17-10-12-19(13-11-17)25-24(30)31-16-18-8-6-5-7-9-18/h5-13H,3-4,14-16H2,1-2H3,(H,25,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196964 (US9206164, 28) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc(Br)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H22BrClN4O2/c1-3-18-15(9-22(30)31)21(4-2)29(28-18)12-13-5-7-14(8-6-13)23-26-19-10-16(24)17(25)11-20(19)27-23/h5-8,10-11H,3-4,9,12H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197042 (US9206164, 106) Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3cc(C)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H24ClFN4O2/c1-4-19-16(10-23(31)32)22(5-2)30(29-19)12-15-7-6-14(9-18(15)26)24-27-20-8-13(3)17(25)11-21(20)28-24/h6-9,11H,4-5,10,12H2,1-3H3,(H,27,28)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196981 (US9206164, 45) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc(Cl)ccc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H23ClN4O2/c1-3-18-17(12-22(29)30)21(4-2)28(27-18)13-14-5-7-15(8-6-14)23-25-19-10-9-16(24)11-20(19)26-23/h5-11H,3-4,12-13H2,1-2H3,(H,25,26)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196943 (US9206164, 4) Show SMILES Cc1nn(Cc2ccc(cc2)-c2cc3ccc(cc3[nH]2)C(F)(F)F)c(C)c1CC(O)=O Show InChI InChI=1S/C23H20F3N3O2/c1-13-19(11-22(30)31)14(2)29(28-13)12-15-3-5-16(6-4-15)20-9-17-7-8-18(23(24,25)26)10-21(17)27-20/h3-10,27H,11-12H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127209 (US8791272, 7.5) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2C)c(C)c1CC(O)=O Show InChI InChI=1S/C26H25N3O3/c1-16-12-23(27-26(32)21-9-8-19-6-4-5-7-20(19)13-21)11-10-22(16)15-29-18(3)24(14-25(30)31)17(2)28-29/h4-13H,14-15H2,1-3H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196963 (US9206164, 27) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc(F)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H22ClFN4O2/c1-3-18-15(9-22(30)31)21(4-2)29(28-18)12-13-5-7-14(8-6-13)23-26-19-10-16(24)17(25)11-20(19)27-23/h5-8,10-11H,3-4,9,12H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127161 (US8791272, 2.37) Show SMILES CCCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)c(C(C)C)c1CC(O)=O Show InChI InChI=1S/C25H28ClN3O3/c1-4-5-22-21(14-23(30)31)24(16(2)3)29(28-22)15-17-6-12-20(13-7-17)27-25(32)18-8-10-19(26)11-9-18/h6-13,16H,4-5,14-15H2,1-3H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197023 (US9206164, 87) Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3cc(Br)ccc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H22BrFN4O2/c1-3-18-16(11-22(30)31)21(4-2)29(28-18)12-14-6-5-13(9-17(14)25)23-26-19-8-7-15(24)10-20(19)27-23/h5-10H,3-4,11-12H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197001 (US9206164, 65) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3c(Cl)cc(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H22Cl2N4O2/c1-3-18-16(11-21(30)31)20(4-2)29(28-18)12-13-5-7-14(8-6-13)23-26-19-10-15(24)9-17(25)22(19)27-23/h5-10H,3-4,11-12H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196969 (US9206164, 33) Show SMILES Cc1nn(Cc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(C)(C)C)c(C)c1CC(O)=O Show InChI InChI=1S/C25H28N4O2/c1-15-20(13-23(30)31)16(2)29(28-15)14-17-6-8-18(9-7-17)24-26-21-11-10-19(25(3,4)5)12-22(21)27-24/h6-12H,13-14H2,1-5H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196944 (US9206164, 5) Show SMILES Cc1nn(Cc2ccc(cc2F)-c2cc3ccc(cc3[nH]2)C(F)(F)F)c(C)c1CC(O)=O Show InChI InChI=1S/C23H19F4N3O2/c1-12-18(10-22(31)32)13(2)30(29-12)11-16-4-3-14(7-19(16)24)20-8-15-5-6-17(23(25,26)27)9-21(15)28-20/h3-9,28H,10-11H2,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197016 (US9206164, 80) Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3cc(Cl)ccc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H22ClFN4O2/c1-3-18-16(11-22(30)31)21(4-2)29(28-18)12-14-6-5-13(9-17(14)25)23-26-19-8-7-15(24)10-20(19)27-23/h5-10H,3-4,11-12H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196991 (US9206164, 55) Show SMILES CCc1nn(Cc2ccc(cc2)-c2nc3cc(C)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H25ClN4O2/c1-4-19-17(11-23(30)31)22(5-2)29(28-19)13-15-6-8-16(9-7-15)24-26-20-10-14(3)18(25)12-21(20)27-24/h6-10,12H,4-5,11,13H2,1-3H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127259 (US8791272, 9.27) Show SMILES CCc1nn(Cc2ccc(cc2F)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H22ClF4N3O3/c1-3-20-16(11-22(33)34)21(4-2)32(31-20)12-14-6-5-13(9-19(14)26)23(35)30-15-7-8-18(25)17(10-15)24(27,28)29/h5-10H,3-4,11-12H2,1-2H3,(H,30,35)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127138 (US8791272, 2.21) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3cccc4CCCCc34)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C27H31N3O3/c1-3-24-23(16-26(31)32)25(4-2)30(29-24)17-18-12-14-20(15-13-18)28-27(33)22-11-7-9-19-8-5-6-10-21(19)22/h7,9,11-15H,3-6,8,10,16-17H2,1-2H3,(H,28,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127186 (US8791272, 3.4) Show SMILES Cc1nn(Cc2ccc(NC(=O)OCc3ccc(Cl)c(Cl)c3)cc2)c(C)c1CC(O)=O Show InChI InChI=1S/C22H21Cl2N3O4/c1-13-18(10-21(28)29)14(2)27(26-13)11-15-3-6-17(7-4-15)25-22(30)31-12-16-5-8-19(23)20(24)9-16/h3-9H,10-12H2,1-2H3,(H,25,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127175 (US8791272, 2.52) Show SMILES CCc1c(CC(O)=O)c(C)nn1Cc1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C23H22F3N3O3/c1-3-20-19(12-21(30)31)14(2)28-29(20)13-15-4-10-18(11-5-15)27-22(32)16-6-8-17(9-7-16)23(24,25)26/h4-11H,3,12-13H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127172 (US8791272, 2.49) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3C)cc2)c(C2CC2)c1CC(O)=O Show InChI InChI=1S/C25H26ClN3O3/c1-3-22-21(13-23(30)31)24(17-6-7-17)29(28-22)14-16-4-9-19(10-5-16)27-25(32)20-11-8-18(26)12-15(20)2/h4-5,8-12,17H,3,6-7,13-14H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127170 (US8791272, 2.46) Show SMILES CCc1c(CC(O)=O)c(nn1Cc1ccc(NC(=O)c2ccc(Cl)cc2C)cc1)C1CC1 Show InChI InChI=1S/C25H26ClN3O3/c1-3-22-21(13-23(30)31)24(17-6-7-17)28-29(22)14-16-4-9-19(10-5-16)27-25(32)20-11-8-18(26)12-15(20)2/h4-5,8-12,17H,3,6-7,13-14H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127219 (US8791272, 7.15) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2Cl)c(C)c1CC(O)=O Show InChI InChI=1S/C21H18Cl3N3O3/c1-11-16(9-20(28)29)12(2)27(26-11)10-14-3-5-15(8-18(14)23)25-21(30)13-4-6-17(22)19(24)7-13/h3-8H,9-10H2,1-2H3,(H,25,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197012 (US9206164, 76) Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3cc(F)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H21ClF2N4O2/c1-3-18-14(8-22(31)32)21(4-2)30(29-18)11-13-6-5-12(7-16(13)25)23-27-19-9-15(24)17(26)10-20(19)28-23/h5-7,9-10H,3-4,8,11H2,1-2H3,(H,27,28)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127189 (US8791272, 3.7) Show SMILES Cc1nn(Cc2ccc(NC(=O)OCc3ccc4ccccc4c3)cc2)c(C)c1CC(O)=O Show InChI InChI=1S/C26H25N3O4/c1-17-24(14-25(30)31)18(2)29(28-17)15-19-8-11-23(12-9-19)27-26(32)33-16-20-7-10-21-5-3-4-6-22(21)13-20/h3-13H,14-16H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127134 (US8791272, 2.17) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(Br)cc3C)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H26BrN3O3/c1-4-21-20(13-23(29)30)22(5-2)28(27-21)14-16-6-9-18(10-7-16)26-24(31)19-11-8-17(25)12-15(19)3/h6-12H,4-5,13-14H2,1-3H3,(H,26,31)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196947 (US9206164, 11) Show SMILES Cc1nn(Cc2ccc(cc2C(F)(F)F)-c2cc3ccc(cc3[nH]2)C(F)(F)F)c(C)c1CC(O)=O Show InChI InChI=1S/C24H19F6N3O2/c1-12-18(10-22(34)35)13(2)33(32-12)11-16-4-3-14(7-19(16)24(28,29)30)20-8-15-5-6-17(23(25,26)27)9-21(15)31-20/h3-9,31H,10-11H2,1-2H3,(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197040 (US9206164, 104) Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3c(Cl)cc(Cl)cc3[nH]2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H21Cl2FN4O2/c1-3-18-15(10-21(31)32)20(4-2)30(29-18)11-13-6-5-12(7-17(13)26)23-27-19-9-14(24)8-16(25)22(19)28-23/h5-9H,3-4,10-11H2,1-2H3,(H,27,28)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM197028 (US9206164, 92) Show SMILES COc1ccc2[nH]c(nc2n1)-c1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1 Show InChI InChI=1S/C21H20FN5O3/c1-11-15(9-19(28)29)12(2)27(26-11)10-14-5-4-13(8-16(14)22)20-23-17-6-7-18(30-3)24-21(17)25-20/h4-8H,9-10H2,1-3H3,(H,28,29)(H,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127160 (US8791272, 2.36) Show SMILES CCCc1nn(Cc2ccc(NC(=O)c3ccc(cc3C)C(F)(F)F)cc2)c(C(C)C)c1CC(O)=O Show InChI InChI=1S/C27H30F3N3O3/c1-5-6-23-22(14-24(34)35)25(16(2)3)33(32-23)15-18-7-10-20(11-8-18)31-26(36)21-12-9-19(13-17(21)4)27(28,29)30/h7-13,16H,5-6,14-15H2,1-4H3,(H,31,36)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127129 (US8791272, 2.5) Show SMILES CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)c(CC)c1CC(O)=O Show InChI InChI=1S/C23H24ClN3O3/c1-3-20-19(13-22(28)29)21(4-2)27(26-20)14-15-5-11-18(12-6-15)25-23(30)16-7-9-17(24)10-8-16/h5-12H,3-4,13-14H2,1-2H3,(H,25,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.75	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM127212 (US8791272, 7.8) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2Cl)c(C)c1CC(O)=O Show InChI InChI=1S/C22H19ClF3N3O3/c1-12-18(10-20(30)31)13(2)29(28-12)11-15-5-8-17(9-19(15)23)27-21(32)14-3-6-16(7-4-14)22(24,25)26/h3-9H,10-11H2,1-2H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196954 (US9206164, 18) Show SMILES Cc1nn(Cc2ccc(cc2)-c2nc3cc4ccccc4cc3[nH]2)c(C)c1CC(O)=O Show InChI InChI=1S/C25H22N4O2/c1-15-21(13-24(30)31)16(2)29(28-15)14-17-7-9-18(10-8-17)25-26-22-11-19-5-3-4-6-20(19)12-23(22)27-25/h3-12H,13-14H2,1-2H3,(H,26,27)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM196945 (US9206164, 6) Show SMILES Cc1nn(Cc2ccc(cc2F)-c2cc3ccc(Cl)cc3[nH]2)c(C)c1CC(O)=O Show InChI InChI=1S/C22H19ClFN3O2/c1-12-18(10-22(28)29)13(2)27(26-12)11-16-4-3-14(7-19(16)24)20-8-15-5-6-17(23)9-21(15)25-20/h3-9,25H,10-11H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US9206164 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TS9
					More data for this Ligand-Target Pair

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