Compile Data Set for Download or QSAR

Found 740 hits with Last Name = 'holzgrabe' and Initial = 'u'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86549 (CAS_213055 | NSC_213055 | TRK-820) Show SMILES CN(C1CCC2(O)C3Cc4ccc(O)c5OC1C2(CCN3CC1CC1)c45)C(=O)C=Cc1ccoc1 |w:28.33,TLB:4:5:8.9.25:18.19.20,6:5:8.9.25:18.19.20| Show InChI InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.0250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86549 (CAS_213055 | NSC_213055 | TRK-820) Show SMILES CN(C1CCC2(O)C3Cc4ccc(O)c5OC1C2(CCN3CC1CC1)c45)C(=O)C=Cc1ccoc1 |w:28.33,TLB:4:5:8.9.25:18.19.20,6:5:8.9.25:18.19.20| Show InChI InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.0750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50241132 (3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...) Show SMILES C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:9:8:4.5.6:1,9:10:4.5.6:1,THB:11:5:1:8.10| Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50241132 (3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...) Show SMILES C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:9:8:4.5.6:1,9:10:4.5.6:1,THB:11:5:1:8.10| Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50241132 (3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...) Show SMILES C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:9:8:4.5.6:1,9:10:4.5.6:1,THB:11:5:1:8.10| Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.437	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50241132 (3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...) Show SMILES C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:9:8:4.5.6:1,9:10:4.5.6:1,THB:11:5:1:8.10| Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50241132 (3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...) Show SMILES C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:9:8:4.5.6:1,9:10:4.5.6:1,THB:11:5:1:8.10| Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497843 (CHEMBL1197177) Show SMILES [H][C@@]12CC[C@]([H])(CC(C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)C |r,TLB:9:7:21:2.3| Show InChI InChI=1S/C18H26NO3/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13/h3-7,14-17,20H,8-12H2,1-2H3/q+1/t14-,15-,17?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50448377 (CHEMBL3121473) Show SMILES C[N+](C)(C)CC#CCOC1=NOCC1 |t:9| Show InChI InChI=1S/C10H17N2O2/c1-12(2,3)7-4-5-8-13-10-6-9-14-11-10/h6-9H2,1-3H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86547 (CAS_135349 | NSC_135349 | U50,488H) Show SMILES CN(C1CCCCC1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50448377 (CHEMBL3121473) Show SMILES C[N+](C)(C)CC#CCOC1=NOCC1 |t:9| Show InChI InChI=1S/C10H17N2O2/c1-12(2,3)7-4-5-8-13-10-6-9-14-11-10/h6-9H2,1-3H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497842 (CHEMBL3323281) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23 |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(21.93,-8.07,;23.41,-4.94,;22,-13.38,;21.94,-11.51,;20.57,-12.24,;20.27,-13.74,;21.3,-13.01,;21.9,-14.78,;22.76,-12.95,;23.79,-13.7,;23.41,-12.18,;23.79,-15.22,;25.09,-15.95,;25.09,-17.44,;26.38,-15.2,;26.38,-13.7,;27.7,-12.97,;27.7,-15.95,;29,-15.2,;30.29,-15.95,;30.29,-17.44,;29,-18.19,;27.7,-17.44,;20.8,-10.36,;20.1,-9.04,;19.25,-10.36,;18.48,-9.02,;16.94,-9.02,;16.16,-7.68,;14.62,-7.68,;13.85,-6.35,;12.29,-6.34,;11.89,-4.84,;13.39,-5.24,;11.53,-7.68,;9.99,-7.69,;8.64,-6.92,;9.98,-6.14,;9.22,-9.04,;7.68,-9.04,;6.91,-10.39,;7.68,-11.72,;5.36,-10.39,;4.6,-11.72,;3.06,-11.73,;2.28,-10.39,;3.05,-9.07,;2.27,-7.74,;3.04,-6.39,;4.58,-6.39,;5.35,-7.72,;6.89,-7.71,;6.88,-6.16,;4.59,-9.06,)| Show InChI InChI=1S/C42H57N3O5.2BrH/c1-42(2,28-43-39(47)35-19-13-17-31-18-14-20-36(38(31)35)40(43)48)29-44(3,4)23-11-6-7-12-24-45(5)32-21-22-33(45)26-34(25-32)50-41(49)37(27-46)30-15-9-8-10-16-30;;/h8-10,13-20,32-34,37,46H,6-7,11-12,21-29H2,1-5H3;2*1H/q+2;;/p-2/t32-,33-,34-,37?,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497835 (ENDO-ATROPINE) Show SMILES CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497842 (CHEMBL3323281) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23 |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(21.93,-8.07,;23.41,-4.94,;22,-13.38,;21.94,-11.51,;20.57,-12.24,;20.27,-13.74,;21.3,-13.01,;21.9,-14.78,;22.76,-12.95,;23.79,-13.7,;23.41,-12.18,;23.79,-15.22,;25.09,-15.95,;25.09,-17.44,;26.38,-15.2,;26.38,-13.7,;27.7,-12.97,;27.7,-15.95,;29,-15.2,;30.29,-15.95,;30.29,-17.44,;29,-18.19,;27.7,-17.44,;20.8,-10.36,;20.1,-9.04,;19.25,-10.36,;18.48,-9.02,;16.94,-9.02,;16.16,-7.68,;14.62,-7.68,;13.85,-6.35,;12.29,-6.34,;11.89,-4.84,;13.39,-5.24,;11.53,-7.68,;9.99,-7.69,;8.64,-6.92,;9.98,-6.14,;9.22,-9.04,;7.68,-9.04,;6.91,-10.39,;7.68,-11.72,;5.36,-10.39,;4.6,-11.72,;3.06,-11.73,;2.28,-10.39,;3.05,-9.07,;2.27,-7.74,;3.04,-6.39,;4.58,-6.39,;5.35,-7.72,;6.89,-7.71,;6.88,-6.16,;4.59,-9.06,)| Show InChI InChI=1S/C42H57N3O5.2BrH/c1-42(2,28-43-39(47)35-19-13-17-31-18-14-20-36(38(31)35)40(43)48)29-44(3,4)23-11-6-7-12-24-45(5)32-21-22-33(45)26-34(25-32)50-41(49)37(27-46)30-15-9-8-10-16-30;;/h8-10,13-20,32-34,37,46H,6-7,11-12,21-29H2,1-5H3;2*1H/q+2;;/p-2/t32-,33-,34-,37?,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50497835 (ENDO-ATROPINE) Show SMILES CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86549 (CAS_213055 | NSC_213055 | TRK-820) Show SMILES CN(C1CCC2(O)C3Cc4ccc(O)c5OC1C2(CCN3CC1CC1)c45)C(=O)C=Cc1ccoc1 |w:28.33,TLB:4:5:8.9.25:18.19.20,6:5:8.9.25:18.19.20| Show InChI InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497834 (CHEMBL3323284) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C42H55N3O6.2BrH/c1-42(2,26-43-39(47)31-19-13-17-29-18-14-20-32(36(29)31)40(43)48)27-44(3,4)21-11-6-7-12-22-45(5)34-23-30(24-35(45)38-37(34)51-38)50-41(49)33(25-46)28-15-9-8-10-16-28;;/h8-10,13-20,30,33-35,37-38,46H,6-7,11-12,21-27H2,1-5H3;2*1H/q+2;;/p-2/t30-,33-,34+,35-,37+,38-,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM86546 (CAS_88373-73-3 | DPDPE | NSC_104787) Show SMILES CC1(C)SSC(C)(C)C(NC(=O)C(N)Cc2ccc(O)cc2)C(=O)NCC(=O)NC(Cc2ccccc2)C(=O)NC1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497835 (ENDO-ATROPINE) Show SMILES CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86548 (CAS_83729-01-5 | NSC_128563 | Salvinorin A) Show SMILES COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(CC21C)c1ccoc1 Show InChI InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497835 (ENDO-ATROPINE) Show SMILES CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497835 (ENDO-ATROPINE) Show SMILES CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50225707 (CHEBI:28973 | Strychnine) Show SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])CC(=O)N6c7ccccc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H] |c:5| Show InChI InChI=1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...				Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01030 BindingDB Entry DOI: 10.7270/Q2HH6PV6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497841 (CHEMBL3323280) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2ccccc2C1=O |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(32.13,-8.94,;23.31,-4.96,;24.54,-13.76,;24.48,-11.89,;23.12,-12.62,;22.82,-14.11,;23.84,-13.39,;24.45,-15.15,;25.3,-13.32,;26.34,-14.07,;25.95,-12.55,;26.34,-15.59,;27.63,-16.32,;27.63,-17.81,;28.92,-15.57,;28.92,-14.07,;30.24,-13.34,;30.24,-16.32,;31.53,-15.57,;32.83,-16.32,;32.83,-17.81,;31.53,-18.56,;30.24,-17.81,;23.34,-10.74,;22.64,-9.42,;21.8,-10.74,;21.03,-9.4,;19.49,-9.4,;18.72,-8.07,;17.17,-8.07,;16.4,-6.73,;14.85,-6.72,;14.45,-5.23,;15.94,-5.63,;14.09,-8.07,;12.54,-8.07,;11.2,-7.3,;12.54,-6.53,;11.78,-9.41,;10.24,-9.42,;9.32,-8.17,;9.79,-6.7,;7.86,-8.66,;6.53,-7.9,;5.2,-8.68,;5.21,-10.22,;6.55,-10.98,;7.87,-10.2,;9.34,-10.67,;9.82,-12.13,)| Show InChI InChI=1S/C38H55N3O5.2BrH/c1-38(2,26-39-35(43)32-17-11-12-18-33(32)36(39)44)27-40(3,4)21-13-6-7-14-22-41(5)29-19-20-30(41)24-31(23-29)46-37(45)34(25-42)28-15-9-8-10-16-28;;/h8-12,15-18,29-31,34,42H,6-7,13-14,19-27H2,1-5H3;2*1H/q+2;;/p-2/t29-,30-,31-,34?,41?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86549 (CAS_213055 | NSC_213055 | TRK-820) Show SMILES CN(C1CCC2(O)C3Cc4ccc(O)c5OC1C2(CCN3CC1CC1)c45)C(=O)C=Cc1ccoc1 |w:28.33,TLB:4:5:8.9.25:18.19.20,6:5:8.9.25:18.19.20| Show InChI InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497841 (CHEMBL3323280) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2ccccc2C1=O |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(32.13,-8.94,;23.31,-4.96,;24.54,-13.76,;24.48,-11.89,;23.12,-12.62,;22.82,-14.11,;23.84,-13.39,;24.45,-15.15,;25.3,-13.32,;26.34,-14.07,;25.95,-12.55,;26.34,-15.59,;27.63,-16.32,;27.63,-17.81,;28.92,-15.57,;28.92,-14.07,;30.24,-13.34,;30.24,-16.32,;31.53,-15.57,;32.83,-16.32,;32.83,-17.81,;31.53,-18.56,;30.24,-17.81,;23.34,-10.74,;22.64,-9.42,;21.8,-10.74,;21.03,-9.4,;19.49,-9.4,;18.72,-8.07,;17.17,-8.07,;16.4,-6.73,;14.85,-6.72,;14.45,-5.23,;15.94,-5.63,;14.09,-8.07,;12.54,-8.07,;11.2,-7.3,;12.54,-6.53,;11.78,-9.41,;10.24,-9.42,;9.32,-8.17,;9.79,-6.7,;7.86,-8.66,;6.53,-7.9,;5.2,-8.68,;5.21,-10.22,;6.55,-10.98,;7.87,-10.2,;9.34,-10.67,;9.82,-12.13,)| Show InChI InChI=1S/C38H55N3O5.2BrH/c1-38(2,26-39-35(43)32-17-11-12-18-33(32)36(39)44)27-40(3,4)21-13-6-7-14-22-41(5)29-19-20-30(41)24-31(23-29)46-37(45)34(25-42)28-15-9-8-10-16-28;;/h8-12,15-18,29-31,34,42H,6-7,13-14,19-27H2,1-5H3;2*1H/q+2;;/p-2/t29-,30-,31-,34?,41?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50497834 (CHEMBL3323284) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C42H55N3O6.2BrH/c1-42(2,26-43-39(47)31-19-13-17-29-18-14-20-32(36(29)31)40(43)48)27-44(3,4)21-11-6-7-12-22-45(5)34-23-30(24-35(45)38-37(34)51-38)50-41(49)33(25-46)28-15-9-8-10-16-28;;/h8-10,13-20,30,33-35,37-38,46H,6-7,11-12,21-27H2,1-5H3;2*1H/q+2;;/p-2/t30-,33-,34+,35-,37+,38-,45?;;/m1../s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497834 (CHEMBL3323284) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C42H55N3O6.2BrH/c1-42(2,26-43-39(47)31-19-13-17-29-18-14-20-32(36(29)31)40(43)48)27-44(3,4)21-11-6-7-12-22-45(5)34-23-30(24-35(45)38-37(34)51-38)50-41(49)33(25-46)28-15-9-8-10-16-28;;/h8-10,13-20,30,33-35,37-38,46H,6-7,11-12,21-27H2,1-5H3;2*1H/q+2;;/p-2/t30-,33-,34+,35-,37+,38-,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497834 (CHEMBL3323284) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C42H55N3O6.2BrH/c1-42(2,26-43-39(47)31-19-13-17-29-18-14-20-32(36(29)31)40(43)48)27-44(3,4)21-11-6-7-12-22-45(5)34-23-30(24-35(45)38-37(34)51-38)50-41(49)33(25-46)28-15-9-8-10-16-28;;/h8-10,13-20,30,33-35,37-38,46H,6-7,11-12,21-27H2,1-5H3;2*1H/q+2;;/p-2/t30-,33-,34+,35-,37+,38-,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497837 (CHEMBL3323283) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C36H49N3O6.2BrH/c1-38(2,20-13-18-37-34(41)27-16-9-10-17-28(27)35(37)42)19-11-4-5-12-21-39(3)30-22-26(23-31(39)33-32(30)45-33)44-36(43)29(24-40)25-14-7-6-8-15-25;;/h6-10,14-17,26,29-33,40H,4-5,11-13,18-24H2,1-3H3;2*1H/q+2;;/p-2/t26-,29-,30+,31-,32+,33-,39?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497837 (CHEMBL3323283) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C36H49N3O6.2BrH/c1-38(2,20-13-18-37-34(41)27-16-9-10-17-28(27)35(37)42)19-11-4-5-12-21-39(3)30-22-26(23-31(39)33-32(30)45-33)44-36(43)29(24-40)25-14-7-6-8-15-25;;/h6-10,14-17,26,29-33,40H,4-5,11-13,18-24H2,1-3H3;2*1H/q+2;;/p-2/t26-,29-,30+,31-,32+,33-,39?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497837 (CHEMBL3323283) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C36H49N3O6.2BrH/c1-38(2,20-13-18-37-34(41)27-16-9-10-17-28(27)35(37)42)19-11-4-5-12-21-39(3)30-22-26(23-31(39)33-32(30)45-33)44-36(43)29(24-40)25-14-7-6-8-15-25;;/h6-10,14-17,26,29-33,40H,4-5,11-13,18-24H2,1-3H3;2*1H/q+2;;/p-2/t26-,29-,30+,31-,32+,33-,39?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86548 (CAS_83729-01-5 | NSC_128563 | Salvinorin A) Show SMILES COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(CC21C)c1ccoc1 Show InChI InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497837 (CHEMBL3323283) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C36H49N3O6.2BrH/c1-38(2,20-13-18-37-34(41)27-16-9-10-17-28(27)35(37)42)19-11-4-5-12-21-39(3)30-22-26(23-31(39)33-32(30)45-33)44-36(43)29(24-40)25-14-7-6-8-15-25;;/h6-10,14-17,26,29-33,40H,4-5,11-13,18-24H2,1-3H3;2*1H/q+2;;/p-2/t26-,29-,30+,31-,32+,33-,39?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497842 (CHEMBL3323281) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23 |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(21.93,-8.07,;23.41,-4.94,;22,-13.38,;21.94,-11.51,;20.57,-12.24,;20.27,-13.74,;21.3,-13.01,;21.9,-14.78,;22.76,-12.95,;23.79,-13.7,;23.41,-12.18,;23.79,-15.22,;25.09,-15.95,;25.09,-17.44,;26.38,-15.2,;26.38,-13.7,;27.7,-12.97,;27.7,-15.95,;29,-15.2,;30.29,-15.95,;30.29,-17.44,;29,-18.19,;27.7,-17.44,;20.8,-10.36,;20.1,-9.04,;19.25,-10.36,;18.48,-9.02,;16.94,-9.02,;16.16,-7.68,;14.62,-7.68,;13.85,-6.35,;12.29,-6.34,;11.89,-4.84,;13.39,-5.24,;11.53,-7.68,;9.99,-7.69,;8.64,-6.92,;9.98,-6.14,;9.22,-9.04,;7.68,-9.04,;6.91,-10.39,;7.68,-11.72,;5.36,-10.39,;4.6,-11.72,;3.06,-11.73,;2.28,-10.39,;3.05,-9.07,;2.27,-7.74,;3.04,-6.39,;4.58,-6.39,;5.35,-7.72,;6.89,-7.71,;6.88,-6.16,;4.59,-9.06,)| Show InChI InChI=1S/C42H57N3O5.2BrH/c1-42(2,28-43-39(47)35-19-13-17-31-18-14-20-36(38(31)35)40(43)48)29-44(3,4)23-11-6-7-12-24-45(5)32-21-22-33(45)26-34(25-32)50-41(49)37(27-46)30-15-9-8-10-16-30;;/h8-10,13-20,32-34,37,46H,6-7,11-12,21-29H2,1-5H3;2*1H/q+2;;/p-2/t32-,33-,34-,37?,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50448377 (CHEMBL3121473) Show SMILES C[N+](C)(C)CC#CCOC1=NOCC1 |t:9| Show InChI InChI=1S/C10H17N2O2/c1-12(2,3)7-4-5-8-13-10-6-9-14-11-10/h6-9H2,1-3H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM86253 (CAS_100929-53-1 | DAMGO | NSC_104742 | US10836728,...) Show SMILES CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)C(Cc1ccccc1)C(=O)NCCO Show InChI InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Temple University Curated by PDSP Ki Database									J Pharmacol Exp Ther 312: 220-30 (2005) Article DOI: 10.1124/jpet.104.073668 BindingDB Entry DOI: 10.7270/Q26T0K6G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497834 (CHEMBL3323284) Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9| Show InChI InChI=1S/C42H55N3O6.2BrH/c1-42(2,26-43-39(47)31-19-13-17-29-18-14-20-32(36(29)31)40(43)48)27-44(3,4)21-11-6-7-12-22-45(5)34-23-30(24-35(45)38-37(34)51-38)50-41(49)33(25-46)28-15-9-8-10-16-28;;/h8-10,13-20,30,33-35,37-38,46H,6-7,11-12,21-27H2,1-5H3;2*1H/q+2;;/p-2/t30-,33-,34+,35-,37+,38-,45?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497841 (CHEMBL3323280) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2ccccc2C1=O |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(32.13,-8.94,;23.31,-4.96,;24.54,-13.76,;24.48,-11.89,;23.12,-12.62,;22.82,-14.11,;23.84,-13.39,;24.45,-15.15,;25.3,-13.32,;26.34,-14.07,;25.95,-12.55,;26.34,-15.59,;27.63,-16.32,;27.63,-17.81,;28.92,-15.57,;28.92,-14.07,;30.24,-13.34,;30.24,-16.32,;31.53,-15.57,;32.83,-16.32,;32.83,-17.81,;31.53,-18.56,;30.24,-17.81,;23.34,-10.74,;22.64,-9.42,;21.8,-10.74,;21.03,-9.4,;19.49,-9.4,;18.72,-8.07,;17.17,-8.07,;16.4,-6.73,;14.85,-6.72,;14.45,-5.23,;15.94,-5.63,;14.09,-8.07,;12.54,-8.07,;11.2,-7.3,;12.54,-6.53,;11.78,-9.41,;10.24,-9.42,;9.32,-8.17,;9.79,-6.7,;7.86,-8.66,;6.53,-7.9,;5.2,-8.68,;5.21,-10.22,;6.55,-10.98,;7.87,-10.2,;9.34,-10.67,;9.82,-12.13,)| Show InChI InChI=1S/C38H55N3O5.2BrH/c1-38(2,26-39-35(43)32-17-11-12-18-33(32)36(39)44)27-40(3,4)21-13-6-7-14-22-41(5)29-19-20-30(41)24-31(23-29)46-37(45)34(25-42)28-15-9-8-10-16-28;;/h8-12,15-18,29-31,34,42H,6-7,13-14,19-27H2,1-5H3;2*1H/q+2;;/p-2/t29-,30-,31-,34?,41?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50497841 (CHEMBL3323280) Show SMILES [Br-].[Br-].[H][C@@]12CC[C@]([H])(C[C@H](C1)OC(=O)C(CO)c1ccccc1)[N+]2(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2ccccc2C1=O |r,wD:9.9,3.0,6.4,TLB:25:23:9.10.8:4.5,11:9:23:4.5,(32.13,-8.94,;23.31,-4.96,;24.54,-13.76,;24.48,-11.89,;23.12,-12.62,;22.82,-14.11,;23.84,-13.39,;24.45,-15.15,;25.3,-13.32,;26.34,-14.07,;25.95,-12.55,;26.34,-15.59,;27.63,-16.32,;27.63,-17.81,;28.92,-15.57,;28.92,-14.07,;30.24,-13.34,;30.24,-16.32,;31.53,-15.57,;32.83,-16.32,;32.83,-17.81,;31.53,-18.56,;30.24,-17.81,;23.34,-10.74,;22.64,-9.42,;21.8,-10.74,;21.03,-9.4,;19.49,-9.4,;18.72,-8.07,;17.17,-8.07,;16.4,-6.73,;14.85,-6.72,;14.45,-5.23,;15.94,-5.63,;14.09,-8.07,;12.54,-8.07,;11.2,-7.3,;12.54,-6.53,;11.78,-9.41,;10.24,-9.42,;9.32,-8.17,;9.79,-6.7,;7.86,-8.66,;6.53,-7.9,;5.2,-8.68,;5.21,-10.22,;6.55,-10.98,;7.87,-10.2,;9.34,-10.67,;9.82,-12.13,)| Show InChI InChI=1S/C38H55N3O5.2BrH/c1-38(2,26-39-35(43)32-17-11-12-18-33(32)36(39)44)27-40(3,4)21-13-6-7-14-22-41(5)29-19-20-30(41)24-31(23-29)46-37(45)34(25-42)28-15-9-8-10-16-28;;/h8-12,15-18,29-31,34,42H,6-7,13-14,19-27H2,1-5H3;2*1H/q+2;;/p-2/t29-,30-,31-,34?,41?;;/m1../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y104A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50121975 ((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...) Show SMILES COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 |r,THB:20:19:12.13:16.15,10:12:18.19:16.15| Show InChI InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Würzburg Curated by ChEMBL					Assay Description Inhibition of human CYP2D6 by Lineweaver-Burk plot				J Med Chem 52: 626-36 (2009) Article DOI: 10.1021/jm801084u BindingDB Entry DOI: 10.7270/Q29C6X9P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50448377 (CHEMBL3121473) Show SMILES C[N+](C)(C)CC#CCOC1=NOCC1 |t:9| Show InChI InChI=1S/C10H17N2O2/c1-12(2,3)7-4-5-8-13-10-6-9-14-11-10/h6-9H2,1-3H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50067004 ((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...) Show SMILES CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H35NO4/c1-4-28(2,3)25(30)26(31)29-20-12-11-17-23(29)27(32)33-24(22-15-9-6-10-16-22)19-18-21-13-7-5-8-14-21/h5-10,13-16,23-24H,4,11-12,17-20H2,1-3H3/t23-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wu£rzburg Curated by ChEMBL					Assay Description Inhibition of FKBP12				J Med Chem 54: 277-83 (2011) Article DOI: 10.1021/jm101156y BindingDB Entry DOI: 10.7270/Q2GF0VG2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50241132 (3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...) Show SMILES C[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:9:8:4.5.6:1,9:10:4.5.6:1,THB:11:5:1:8.10| Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Displacement of [3H]-NMS from human muscarinic M2 Y104A mutant expressed in Flp-In-CHO cells by liquid scintillation counting				J Med Chem 57: 6739-50 (2014) Article DOI: 10.1021/jm500790x BindingDB Entry DOI: 10.7270/Q2RJ4NGM
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50067004 ((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...) Show SMILES CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H35NO4/c1-4-28(2,3)25(30)26(31)29-20-12-11-17-23(29)27(32)33-24(22-15-9-6-10-16-22)19-18-21-13-7-5-8-14-21/h5-10,13-16,23-24H,4,11-12,17-20H2,1-3H3/t23-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human FKBP12 expressed in Escherichia coli using succinyl-Ala-Phe-Pro-Phe-4-nitroanilide as substrate				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00911 BindingDB Entry DOI: 10.7270/Q22V2KW9
					More data for this Ligand-Target Pair				3D Structure (crystal)

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