Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurotensin receptor type 1 (MOUSE) | BDBM50281791 (Ac-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50240845 ((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 0.0180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281781 (Ac-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL2645...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071733 (CHEMBL413196 | Compound GRP) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071745 (CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 0.0680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50290967 (1-{(5R,7S,8S)-8-[(2-Benzofuran-4-yl-acetyl)-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell line | Bioorg Med Chem Lett 7: 291-296 (1997) Article DOI: 10.1016/S0960-894X(96)00615-4 BindingDB Entry DOI: 10.7270/Q2G160VS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281785 ((S)-2-{2-[(S)-2-{[(S)-1-((S)-2-{(S)-2-[((S)-1-Acet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281793 (Ac-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281795 (Ac-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50240844 ((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-2-((S)-2-aceta...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM85484 (Bombesin) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071735 ((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071739 ((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50130880 (CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration producing half maximal inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptor in neonatal mouse whole brain (minus cereb... | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281784 (Ac-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281787 ((1S,4R)-2-{2-[2-({(S)-1-[(S)-2-((S)-2-Amino-propio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human)) | BDBM21147 ((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Cholecystokinin type B receptor | Bioorg Med Chem Lett 3: 799-802 (1993) Article DOI: 10.1016/S0960-894X(00)80669-1 BindingDB Entry DOI: 10.7270/Q29S1QZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071750 ((S)-3-(1H-Indol-3-yl)-2-methyl-N-[1-(4-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071746 ((S)-2-[3-(4-Cyano-phenyl)-ureido]-3-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071748 ((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071736 ((S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071743 ((S)-3-(1H-Indol-3-yl)-N-[1-(4-methoxy-phenyl)-cycl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071741 ((S)-N-[1-(4-Dimethylamino-phenyl)-cyclohexylmethyl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000091 ((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071742 ((S)-N-[1-(4-Ethoxy-phenyl)-cyclohexylmethyl]-3-(1H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071738 ((S)-N-[1-(4-Hydroxy-phenyl)-cyclohexylmethyl]-3-(1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50088375 (1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of binding of [3H]-U-69,593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell line | Bioorg Med Chem Lett 7: 291-296 (1997) Article DOI: 10.1016/S0960-894X(96)00615-4 BindingDB Entry DOI: 10.7270/Q2G160VS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071744 (AcBB(7-14) | CHEMBL314375) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50367937 (CHEMBL1202931) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity against Opioid receptor kappa 1 | J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008858 (2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-... | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281794 ((S)-2-{(2S,3R)-2-[(S)-2-{2-[2-((S)-2-(S)-Amino-5-g...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071737 ((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(3-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071739 ((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonistic activity against cloned human Bombesin receptor bb2 labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells; 0.66-1.3 | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008852 (2-Methyl-acenaphthene-1-carboxylic acid (7-imidazo...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071749 ((S)-3-(1H-Indol-3-yl)-N-[1-(4-isopropyl-phenyl)-cy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50281632 ((2S)-1-{(2S)-2-[(lambda~4~-sulfanylmethyl)amino]pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Angiotensin I converting enzyme | Bioorg Med Chem Lett 3: 799-802 (1993) Article DOI: 10.1016/S0960-894X(00)80669-1 BindingDB Entry DOI: 10.7270/Q29S1QZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50000091 ((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor mu 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human)) | BDBM50281634 (3-{(R)-2-Amino-2-[(R)-2-(3-carboxy-propionylamino)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Cholecystokinin type B receptor | Bioorg Med Chem Lett 3: 799-802 (1993) Article DOI: 10.1016/S0960-894X(00)80669-1 BindingDB Entry DOI: 10.7270/Q29S1QZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity towards mu opioid receptor was determined | J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor mu 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor (Mus musculus-MOUSE) | BDBM50002477 ((S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortex | J Med Chem 30: 729-32 (1987) BindingDB Entry DOI: 10.7270/Q2KK9F0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM85484 (Bombesin) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor (Mus musculus-MOUSE) | BDBM50226755 (CHEMBL415630) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortex | J Med Chem 30: 729-32 (1987) BindingDB Entry DOI: 10.7270/Q2KK9F0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (MOUSE) | BDBM50281782 ((1S,4R)-2-{2-[2-[((S)-{(S)-1-[2-((S)-2-Amino-5-gua...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum) | Bioorg Med Chem Lett 3: 949-952 (1993) Article DOI: 10.1016/S0960-894X(00)80698-8 BindingDB Entry DOI: 10.7270/Q2CJ8DDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071734 ((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071744 (AcBB(7-14) | CHEMBL314375) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071740 ((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071753 ((S)-3-(1H-Indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor type A (Homo sapiens (Human)) | BDBM50281633 (3-[(R)-2-Amino-2-((S)-1-benzyl-2-carboxy-ethylcarb...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against CCK-A receptor | Bioorg Med Chem Lett 3: 799-802 (1993) Article DOI: 10.1016/S0960-894X(00)80669-1 BindingDB Entry DOI: 10.7270/Q29S1QZZ | |||||||||||
More data for this Ligand-Target Pair |
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