Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071733 (CHEMBL413196 | Compound GRP) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071745 (CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 0.0680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM85484 (Bombesin) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human GRP(gastrin releasing peptide) receptors stably expressed in CHO cells | Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM85484 (Bombesin) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071735 ((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071739 ((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071750 ((S)-3-(1H-Indol-3-yl)-2-methyl-N-[1-(4-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071746 ((S)-2-[3-(4-Cyano-phenyl)-ureido]-3-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071748 ((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(4-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071736 ((S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071743 ((S)-3-(1H-Indol-3-yl)-N-[1-(4-methoxy-phenyl)-cycl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071741 ((S)-N-[1-(4-Dimethylamino-phenyl)-cyclohexylmethyl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50000091 ((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071742 ((S)-N-[1-(4-Ethoxy-phenyl)-cyclohexylmethyl]-3-(1H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071738 ((S)-N-[1-(4-Hydroxy-phenyl)-cyclohexylmethyl]-3-(1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071744 (AcBB(7-14) | CHEMBL314375) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50288252 (Bombesin analogue | CHEMBL269432) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human GRP(gastrin releasing peptide) receptors stably expressed in CHO cells | Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50367937 (CHEMBL1202931) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity against Opioid receptor kappa 1 | J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008858 (2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-... | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071737 ((S)-3-(1H-Indol-3-yl)-2-methyl-2-[3-(3-nitro-pheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071739 ((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonistic activity against cloned human Bombesin receptor bb2 labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells; 0.66-1.3 | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008852 (2-Methyl-acenaphthene-1-carboxylic acid (7-imidazo...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071749 ((S)-3-(1H-Indol-3-yl)-N-[1-(4-isopropyl-phenyl)-cy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50000091 ((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor mu 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity towards mu opioid receptor was determined | J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor (Mus musculus-MOUSE) | BDBM50002477 ((S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortex | J Med Chem 30: 729-32 (1987) BindingDB Entry DOI: 10.7270/Q2KK9F0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor mu 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor (Mus musculus-MOUSE) | BDBM50226755 (CHEMBL415630) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortex | J Med Chem 30: 729-32 (1987) BindingDB Entry DOI: 10.7270/Q2KK9F0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM85484 (Bombesin) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM85484 (Bombesin) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cells | Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50288252 (Bombesin analogue | CHEMBL269432) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cells | Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071734 ((S)-2-[3-(3,4-Dichloro-phenyl)-ureido]-3-(1H-indol...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071744 (AcBB(7-14) | CHEMBL314375) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071740 ((S)-2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071753 ((S)-3-(1H-Indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor (Mus musculus-MOUSE) | BDBM50024317 (3-{2-[2-Amino-3-(1H-indol-3-yl)-propionylamino]-4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]pentagastrin from Cholecystokinin receptor of mouse cerebral cortex | J Med Chem 30: 729-32 (1987) BindingDB Entry DOI: 10.7270/Q2KK9F0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50018786 (CHEMBL538309 | N-(2-Azocan-1-yl-cyclohexyl)-N-meth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071755 ((S)-3-(1H-Indol-3-yl)-N-[1-(2-methoxy-phenyl)-cycl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008857 (CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-... | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071743 ((S)-3-(1H-Indol-3-yl)-N-[1-(4-methoxy-phenyl)-cycl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin | J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity against Opioid receptor kappa 1 | J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity towards opioid receptor kappa was determined | J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50018768 (CHEMBL556957 | N-(2-Azepan-1-yl-cyclohexyl)-2-(4-c...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50018762 (2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cy...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50018767 (CHEMBL535581 | N-(2-Azocan-1-yl-cyclohexyl)-N-meth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gastrin-releasing peptide receptor (Homo sapiens (Human)) | BDBM50071742 ((S)-N-[1-(4-Ethoxy-phenyl)-cyclohexylmethyl]-3-(1H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin. | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071754 ((S)-2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-in...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against human NMB receptor was determined | Bioorg Med Chem Lett 6: 2617-2622 (1996) Article DOI: 10.1016/0960-894X(96)00481-7 BindingDB Entry DOI: 10.7270/Q2NC61QD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071754 ((S)-2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-in...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cambridge University Forvie Site Curated by ChEMBL | Assay Description Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | Bioorg Med Chem Lett 8: 2589-94 (1999) BindingDB Entry DOI: 10.7270/Q2DB82B4 | |||||||||||
More data for this Ligand-Target Pair |
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