Compile Data Set for Download or QSAR

Found 412 hits with Last Name = 'hunter' and Initial = 'jc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23 Show InChI InChI=1S/C28H36N2O2/c1-19-21-10-5-8-20-9-6-11-22(26(20)21)25(19)27(31)29(2)23-12-14-28(13-7-17-32-28)18-24(23)30-15-3-4-16-30/h5-6,8-11,19,23-25H,3-4,7,12-18H2,1-2H3/t19?,23-,24-,25?,28?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50367937 (CHEMBL1202931) Show SMILES CN([C@@H]1CC[C@]2(CCCO2)C[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 |r| Show InChI InChI=1S/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1				J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008858 (2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008852 (2-Methyl-acenaphthene-1-carboxylic acid (7-imidazo...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCNC2)c2cccc3cccc1c23 Show InChI InChI=1S/C27H35N3O2/c1-18-20-8-3-6-19-7-4-9-21(25(19)20)24(18)26(31)29(2)22-10-12-27(11-5-15-32-27)16-23(22)30-14-13-28-17-30/h3-4,6-9,18,22-24,28H,5,10-17H2,1-2H3/t18?,22-,23-,24?,27?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards mu opioid receptor was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008857 (CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C26H34N2O2/c1-27(25(29)18-21-10-6-9-20-8-2-3-11-22(20)21)23-12-14-26(13-7-17-30-26)19-24(23)28-15-4-5-16-28/h2-3,6,8-11,23-24H,4-5,7,12-19H2,1H3/t23-,24-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1				J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017495 (2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2O2S/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017500 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2OS/c1-23(19-9-3-2-4-10-20(19)24-13-5-6-14-24)22(25)16-17-8-7-11-21-18(17)12-15-26-21/h7-8,11-12,15,19-20H,2-6,9-10,13-14,16H2,1H3/t19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017488 (2-Benzofuran-4-yl-N-(4,5-dimethoxy-2-pyrrolidin-1-...) Show SMILES CO[C@H]1C[C@@H]([C@H](C[C@H]1OC)N1CCCC1)N(C)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C23H32N2O4/c1-24(23(26)13-16-7-6-8-20-17(16)9-12-29-20)18-14-21(27-2)22(28-3)15-19(18)25-10-4-5-11-25/h6-9,12,18-19,21-22H,4-5,10-11,13-15H2,1-3H3/t18-,19-,21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50013147 (2-Benzo[b]thiophen-4-yl-N-(4,5-dimethoxy-2-pyrroli...) Show SMILES CO[C@H]1CC([C@H](C[C@H]1OC)N1CCCC1)N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C23H32N2O3S/c1-24(23(26)13-16-7-6-8-22-17(16)9-12-29-22)18-14-20(27-2)21(28-3)15-19(18)25-10-4-5-11-25/h6-9,12,18-21H,4-5,10-11,13-15H2,1-3H3/t18?,19-,20-,21+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1				J Med Chem 33: 286-91 (1990) BindingDB Entry DOI: 10.7270/Q2DJ5G7P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017498 (2-Benzofuran-4-yl-N-[2-(3-hydroxymethyl-pyrrolidin...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C22H30N2O3/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017494 (2-Benzo[b]thiophen-7-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2ccsc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-9-2-3-10-19(18)23-12-4-5-13-23)20(24)15-17-8-6-7-16-11-14-25-21(16)17/h6-8,11,14,18-19H,2-5,9-10,12-13,15H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50013147 (2-Benzo[b]thiophen-4-yl-N-(4,5-dimethoxy-2-pyrroli...) Show SMILES CO[C@H]1CC([C@H](C[C@H]1OC)N1CCCC1)N(C)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C23H32N2O3S/c1-24(23(26)13-16-7-6-8-22-17(16)9-12-29-22)18-14-20(27-2)21(28-3)15-19(18)25-10-4-5-11-25/h6-9,12,18-21H,4-5,10-11,13-15H2,1-3H3/t18?,19-,20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017504 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=S)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2S2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008855 (4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxyl...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 Show InChI InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017499 (2-Benzo[b]thiophen-3-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1csc2ccccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-9-3-4-10-19(18)23-12-6-7-13-23)21(24)14-16-15-25-20-11-5-2-8-17(16)20/h2,5,8,11,15,18-19H,3-4,6-7,9-10,12-14H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017489 (2-Benzo[b]thiophen-5-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc2sccc2c1 Show InChI InChI=1S/C21H28N2OS/c1-22(18-6-2-3-7-19(18)23-11-4-5-12-23)21(24)15-16-8-9-20-17(14-16)10-13-25-20/h8-10,13-14,18-19H,2-7,11-12,15H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50452622 (CHEMBL2093981) Show SMILES Cl.CN([C@@H]1CCCC[C@H]1N1CCC[C@H]1CO)C(=O)Cc1cccc2sccc12 |r| Show InChI InChI=1S/C22H30N2O2S.ClH/c1-23(22(26)14-16-6-4-10-21-18(16)11-13-27-21)19-8-2-3-9-20(19)24-12-5-7-17(24)15-25;/h4,6,10-11,13,17,19-20,25H,2-3,5,7-9,12,14-15H2,1H3;1H/t17-,19+,20+;/m0./s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017501 (2-Benzo[b]thiophen-6-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc2ccsc2c1 Show InChI InChI=1S/C21H28N2OS/c1-22(18-6-2-3-7-19(18)23-11-4-5-12-23)21(24)15-16-8-9-17-10-13-25-20(17)14-16/h8-10,13-14,18-19H,2-7,11-12,15H2,1H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017497 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCC[C@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C20H26N2OS/c1-21(17-7-5-8-18(17)22-11-2-3-12-22)20(23)14-15-6-4-9-19-16(15)10-13-24-19/h4,6,9-10,13,17-18H,2-3,5,7-8,11-12,14H2,1H3/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	154	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 (Homo sapiens (Human))	BDBM50209651 (CHEMBL3883384) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3NC(=O)C=C)n2)cc1 Show InChI InChI=1S/C24H26ClN7O/c1-3-22(33)28-20-6-4-5-7-21(20)29-23-19(25)16-26-24(30-23)27-17-8-10-18(11-9-17)32-14-12-31(2)13-15-32/h3-11,16H,1,12-15H2,2H3,(H,28,33)(H2,26,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Time-dependent inhibition of TAB1 fused TAK1 (unknown origin) using FAM-LRRKtide as substrate by mobility shift assay				Bioorg Med Chem 25: 838-846 (2017) Article DOI: 10.1016/j.bmc.2016.11.035 BindingDB Entry DOI: 10.7270/Q2Z89FD7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008853 (2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23 Show InChI InChI=1S/C26H33BrN2O2S/c1-28(20-10-12-26(11-5-15-31-26)16-21(20)29-13-2-3-14-29)25(30)18-8-9-19-23-17(18)6-4-7-22(23)32-24(19)27/h4,6-7,18,20-21H,2-3,5,8-16H2,1H3/t18?,20-,21-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008853 (2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23 Show InChI InChI=1S/C26H33BrN2O2S/c1-28(20-10-12-26(11-5-15-31-26)16-21(20)29-13-2-3-14-29)25(30)18-8-9-19-23-17(18)6-4-7-22(23)32-24(19)27/h4,6-7,18,20-21H,2-3,5,8-16H2,1H3/t18?,20-,21-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008851 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CC(C(=O)N(C)[C@H]1CCCC[C@@H]1N1CCCC1)c1cccc2sccc12 Show InChI InChI=1S/C22H30N2OS/c1-16(17-8-7-11-21-18(17)12-15-26-21)22(25)23(2)19-9-3-4-10-20(19)24-13-5-6-14-24/h7-8,11-12,15-16,19-20H,3-6,9-10,13-14H2,1-2H3/t16?,19-,20-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the Opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008851 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CC(C(=O)N(C)[C@H]1CCCC[C@@H]1N1CCCC1)c1cccc2sccc12 Show InChI InChI=1S/C22H30N2OS/c1-16(17-8-7-11-21-18(17)12-15-26-21)22(25)23(2)19-9-3-4-10-20(19)24-13-5-6-14-24/h7-8,11-12,15-16,19-20H,3-6,9-10,13-14H2,1-2H3/t16?,19-,20-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008851 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CC(C(=O)N(C)[C@H]1CCCC[C@@H]1N1CCCC1)c1cccc2sccc12 Show InChI InChI=1S/C22H30N2OS/c1-16(17-8-7-11-21-18(17)12-15-26-21)22(25)23(2)19-9-3-4-10-20(19)24-13-5-6-14-24/h7-8,11-12,15-16,19-20H,3-6,9-10,13-14H2,1-2H3/t16?,19-,20-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017510 (CHEMBL540277 | Succinic acid bis-(1-{2-[(2-benzofu...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCC(COC(=O)CCC(=O)OCC2CCN(C2)[C@@H]2CCCC[C@H]2N(C)C(=O)Cc2cccc3occc23)C1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C48H62N4O8/c1-49(45(53)27-35-9-7-15-43-37(35)21-25-57-43)39-11-3-5-13-41(39)51-23-19-33(29-51)31-59-47(55)17-18-48(56)60-32-34-20-24-52(30-34)42-14-6-4-12-40(42)50(2)46(54)28-36-10-8-16-44-38(36)22-26-58-44/h7-10,15-16,21-22,25-26,33-34,39-42H,3-6,11-14,17-20,23-24,27-32H2,1-2H3/t33?,34?,39-,40+,41-,42+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017507 (CHEMBL553665 | Pentanedioic acid bis-(1-{2-[(2-ben...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCC(COC(=O)CCCC(=O)OCC2CCN(C2)[C@@H]2CCCC[C@H]2N(C)C(=O)Cc2cccc3occc23)C1)C(=O)Cc1cccc2occc12 Show InChI InChI=1S/C49H64N4O8/c1-50(46(54)28-36-10-7-16-44-38(36)22-26-58-44)40-12-3-5-14-42(40)52-24-20-34(30-52)32-60-48(56)18-9-19-49(57)61-33-35-21-25-53(31-35)43-15-6-4-13-41(43)51(2)47(55)29-37-11-8-17-45-39(37)23-27-59-45/h7-8,10-11,16-17,22-23,26-27,34-35,40-43H,3-6,9,12-15,18-21,24-25,28-33H2,1-2H3/t34?,35?,40-,41+,42-,43+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23 Show InChI InChI=1S/C28H36N2O2/c1-19-21-10-5-8-20-9-6-11-22(26(20)21)25(19)27(31)29(2)23-12-14-28(13-7-17-32-28)18-24(23)30-15-3-4-16-30/h5-6,8-11,19,23-25H,3-4,7,12-18H2,1-2H3/t19?,23-,24-,25?,28?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017492 (Benzo[b]thiophen-4-yl-acetic acid 2-pyrrolidin-1-y...) Show SMILES O=C(Cc1cccc2sccc12)O[C@@H]1CCCC[C@H]1N1CCCC1 Show InChI InChI=1S/C20H25NO2S/c22-20(14-15-6-5-9-19-16(15)10-13-24-19)23-18-8-2-1-7-17(18)21-11-3-4-12-21/h5-6,9-10,13,17-18H,1-4,7-8,11-12,14H2/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	261	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008853 (2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23 Show InChI InChI=1S/C26H33BrN2O2S/c1-28(20-10-12-26(11-5-15-31-26)16-21(20)29-13-2-3-14-29)25(30)18-8-9-19-23-17(18)6-4-7-22(23)32-24(19)27/h4,6-7,18,20-21H,2-3,5,8-16H2,1H3/t18?,20-,21-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	272	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008853 (2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-...) Show SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23 Show InChI InChI=1S/C26H33BrN2O2S/c1-28(20-10-12-26(11-5-15-31-26)16-21(20)29-13-2-3-14-29)25(30)18-8-9-19-23-17(18)6-4-7-22(23)32-24(19)27/h4,6-7,18,20-21H,2-3,5,8-16H2,1H3/t18?,20-,21-,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	272	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalin				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008852 (2-Methyl-acenaphthene-1-carboxylic acid (7-imidazo...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCNC2)c2cccc3cccc1c23 Show InChI InChI=1S/C27H35N3O2/c1-18-20-8-3-6-19-7-4-9-21(25(19)20)24(18)26(31)29(2)22-10-12-27(11-5-15-32-27)16-23(22)30-14-13-28-17-30/h3-4,6-9,18,22-24,28H,5,10-17H2,1-2H3/t18?,22-,23-,24?,27?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	273	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017505 (2-Benzo[b]thiophen-4-yl-N-(2-pyrrolidin-1-yl-cyclo...) Show SMILES O=C(Cc1cccc2sccc12)N[C@@H]1CCCC[C@H]1N1CCCC1 Show InChI InChI=1S/C20H26N2OS/c23-20(14-15-6-5-9-19-16(15)10-13-24-19)21-17-7-1-2-8-18(17)22-11-3-4-12-22/h5-6,9-10,13,17-18H,1-4,7-8,11-12,14H2,(H,21,23)/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	333	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards Opioid receptor kappa 1 was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008854 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the Opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50017501 (2-Benzo[b]thiophen-6-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc2ccsc2c1 Show InChI InChI=1S/C21H28N2OS/c1-22(18-6-2-3-7-19(18)23-11-4-5-12-23)21(24)15-16-8-9-17-10-13-25-20(17)14-16/h8-10,13-14,18-19H,2-7,11-12,15H2,1H3/t18-,19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	425	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50017489 (2-Benzo[b]thiophen-5-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc2sccc2c1 Show InChI InChI=1S/C21H28N2OS/c1-22(18-6-2-3-7-19(18)23-11-4-5-12-23)21(24)15-16-8-9-20-17(14-16)10-13-25-20/h8-10,13-14,18-19H,2-7,11-12,15H2,1H3/t18-,19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	475	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50017495 (2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2O2S/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50008856 (2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-...) Show SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23 Show InChI InChI=1S/C28H36N2O2/c1-19-21-10-5-8-20-9-6-11-22(26(20)21)25(19)27(31)29(2)23-12-14-28(13-7-17-32-28)18-24(23)30-15-3-4-16-30/h5-6,8-11,19,23-25H,3-4,7,12-18H2,1-2H3/t19?,23-,24-,25?,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	578	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Compound was evaluated for the opioid receptor delta affinity				J Med Chem 34: 190-4 (1991) BindingDB Entry DOI: 10.7270/Q2J103SG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50017494 (2-Benzo[b]thiophen-7-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2ccsc12 Show InChI InChI=1S/C21H28N2OS/c1-22(18-9-2-3-10-19(18)23-12-4-5-13-23)20(24)15-17-8-6-7-16-11-14-25-21(16)17/h6-8,11,14,18-19H,2-5,9-10,12-13,15H2,1H3/t18-,19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50017504 (2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=S)Cc1cccc2sccc12 Show InChI InChI=1S/C21H28N2S2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards mu opioid receptor was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair

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