Found 220 hits with Last Name = 'kapilashrami' and Initial = 'k' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93049
(TLM analog, 6)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(C(=O)C(F)(F)F)C1=O |r| Show InChI InChI=1S/C12H11F3O3S/c1-4-6(2)5-11(3)8(16)7(10(18)19-11)9(17)12(13,14)15/h4-5,7H,1H2,2-3H3/b6-5+/t7?,11-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 460 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93048
(TLM analog, 5)Show InChI InChI=1S/C12H14O3S/c1-5-7(2)6-12(4)10(14)9(8(3)13)11(15)16-12/h5-6,9H,1H2,2-4H3/b7-6+/t9?,12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM50241313
((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)Show InChI InChI=1S/C11H14O2S/c1-5-7(2)6-11(4)9(12)8(3)10(13)14-11/h5-6,8H,1H2,2-4H3/b7-6+/t8?,11-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93046
(TLM analog, 3)Show InChI InChI=1S/C12H16O2S/c1-5-8(3)7-12(4)10(13)9(6-2)11(14)15-12/h5,7,9H,1,6H2,2-4H3/b8-7+/t9?,12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93054
(TLM analog, 11)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(C(=O)CCCCc2ccc(cc2)-c2ccccc2)C1=O |r| Show InChI InChI=1S/C27H28O3S/c1-4-19(2)18-27(3)25(29)24(26(30)31-27)23(28)13-9-8-10-20-14-16-22(17-15-20)21-11-6-5-7-12-21/h4-7,11-12,14-18,24H,1,8-10,13H2,2-3H3/b19-18+/t24?,27-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93048
(TLM analog, 5)Show InChI InChI=1S/C12H14O3S/c1-5-7(2)6-12(4)10(14)9(8(3)13)11(15)16-12/h5-6,9H,1H2,2-4H3/b7-6+/t9?,12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93049
(TLM analog, 6)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(C(=O)C(F)(F)F)C1=O |r| Show InChI InChI=1S/C12H11F3O3S/c1-4-6(2)5-11(3)8(16)7(10(18)19-11)9(17)12(13,14)15/h4-5,7H,1H2,2-3H3/b6-5+/t7?,11-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93059
(TLM analog, 16)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCCCc2ccc(cc2)-c2ccccc2)C1=O |r| Show InChI InChI=1S/C26H28O2S/c1-4-19(2)18-26(3)24(27)23(25(28)29-26)13-9-8-10-20-14-16-22(17-15-20)21-11-6-5-7-12-21/h4-7,11-12,14-18,23H,1,8-10,13H2,2-3H3/b19-18+/t23?,26-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93047
(TLM analog, 4)Show InChI InChI=1S/C13H18O2S/c1-5-7-10-11(14)13(4,16-12(10)15)8-9(3)6-2/h6,8,10H,2,5,7H2,1,3-4H3/b9-8+/t10?,13-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93051
(TLM analog, 8)Show SMILES COC(=O)C1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O |r| Show InChI InChI=1S/C12H14O4S/c1-5-7(2)6-12(3)9(13)8(10(14)16-4)11(15)17-12/h5-6,8H,1H2,2-4H3/b7-6+/t8?,12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93060
(TLM analog, 17)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCCCn2cc(CNC(=O)c3ccc(NS(=O)(=O)c4ccc(F)cc4)cc3)nn2)C1=O |r| Show InChI InChI=1S/C30H32FN5O5S2/c1-4-20(2)17-30(3)27(37)26(29(39)42-30)7-5-6-16-36-19-24(33-35-36)18-32-28(38)21-8-12-23(13-9-21)34-43(40,41)25-14-10-22(31)11-15-25/h4,8-15,17,19,26,34H,1,5-7,16,18H2,2-3H3,(H,32,38)/b20-17+/t26?,30-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93045
(TLM analog, 2)Show InChI InChI=1S/C10H12O2S/c1-4-7(2)6-10(3)8(11)5-9(12)13-10/h4,6H,1,5H2,2-3H3/b7-6+/t10-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 4.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93050
(TLM analog, 7)Show SMILES CCCC(=O)C1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O |r| Show InChI InChI=1S/C14H18O3S/c1-5-7-10(15)11-12(16)14(4,18-13(11)17)8-9(3)6-2/h6,8,11H,2,5,7H2,1,3-4H3/b9-8+/t11?,14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 6.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93057
(TLM analog, 14)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCCCc2ccc(F)cc2)C1=O |r| Show InChI InChI=1S/C20H23FO2S/c1-4-14(2)13-20(3)18(22)17(19(23)24-20)8-6-5-7-15-9-11-16(21)12-10-15/h4,9-13,17H,1,5-8H2,2-3H3/b14-13+/t17?,20-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93058
(TLM analog, 15)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCCCc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C20H23ClO2S/c1-4-14(2)13-20(3)18(22)17(19(23)24-20)8-6-5-7-15-9-11-16(21)12-10-15/h4,9-13,17H,1,5-8H2,2-3H3/b14-13+/t17?,20-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 7.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93056
(TLM analog, 13)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCc2ccc(C)cc2)C1=O |r| Show InChI InChI=1S/C19H22O2S/c1-5-13(2)12-19(4)17(20)16(18(21)22-19)11-10-15-8-6-14(3)7-9-15/h5-9,12,16H,1,10-11H2,2-4H3/b13-12+/t16?,19-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 9.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93053
(TLM analog, 10)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(C(=O)c2ccccc2C(O)=O)C1=O |r| Show InChI InChI=1S/C18H16O5S/c1-4-10(2)9-18(3)15(20)13(17(23)24-18)14(19)11-7-5-6-8-12(11)16(21)22/h4-9,13H,1H2,2-3H3,(H,21,22)/b10-9+/t13?,18-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93052
(TLM analog, 9)Show SMILES CCCCCCCCCCCCCCCC(=O)C1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O |r| Show InChI InChI=1S/C26H42O3S/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-22(27)23-24(28)26(4,30-25(23)29)20-21(3)6-2/h6,20,23H,2,5,7-19H2,1,3-4H3/b21-20+/t23?,26-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM50241313
((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)Show InChI InChI=1S/C11H14O2S/c1-5-7(2)6-11(4)9(12)8(3)10(13)14-11/h5-6,8H,1H2,2-4H3/b7-6+/t8?,11-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 1.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93047
(TLM analog, 4)Show InChI InChI=1S/C13H18O2S/c1-5-7-10-11(14)13(4,16-12(10)15)8-9(3)6-2/h6,8,10H,2,5,7H2,1,3-4H3/b9-8+/t10?,13-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 3.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93046
(TLM analog, 3)Show InChI InChI=1S/C12H16O2S/c1-5-8(3)7-12(4)10(13)9(6-2)11(14)15-12/h5,7,9H,1,6H2,2-4H3/b8-7+/t9?,12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 3.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
3-oxoacyl-[acyl-carrier-protein] synthase 1 [C171Q]
(Mycobacterium tuberculosis) | BDBM214777
(TLM18)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCCCN=[N+]=[N-])=C1O |r,c:17| Show InChI InChI=1S/C14H19N3O2S/c1-4-10(2)9-14(3)12(18)11(13(19)20-14)7-5-6-8-16-17-15/h4,9,18H,1,5-8H2,2-3H3/b10-9+/t14-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| 3.84E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
University of Wuerzburg
| Assay Description Binding of TLM18 to wild-type and mutant KasA was quantified by monitoring changes in the intrinsic tryptophan fluorescence of the enzyme at waveleng... |
J Biol Chem 288: 34190-204 (2013)
Article DOI: 10.1074/jbc.M113.511436 BindingDB Entry DOI: 10.7270/Q22F7M8D |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
3-oxoacyl-[acyl-carrier-protein] synthase 1
(Mycobacterium tuberculosis) | BDBM93055
(TLM analog, 12)Show SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(CCc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C18H19ClO2S/c1-4-12(2)11-18(3)16(20)15(17(21)22-18)10-7-13-5-8-14(19)9-6-13/h4-6,8-9,11,15H,1,7,10H2,2-3H3/b12-11+/t15?,18-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
Institute for Chemical Biology & Drug Discovery
| Assay Description Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e... |
J Biol Chem 288: 6045-52 (2013)
Article DOI: 10.1074/jbc.M112.414516 BindingDB Entry DOI: 10.7270/Q2KP80S4 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518186
(US11111247, Example 17)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518192
(US11111247, Example 22)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(cc3)N3CCN(C)CC3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM102619
(K02288a | US10688093, Compound 382_0087_0284 | US1...)Show InChI InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518173
(US11111247, Example 9)Show SMILES C[C@@H]1CN(CCN1)c1ccc(cn1)-c1n[nH]c2cnc(nc12)N1[C@@H](C)CN(C[C@H]1C)C(=O)N1CCCC1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518193
(US11111247, Example 23)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(N4CCN(C)CC4)c(F)c3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518194
(US11111247, Example 24)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN(C)CC3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human)) | BDBM102619
(K02288a | US10688093, Compound 382_0087_0284 | US1...)Show InChI InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518135
(US11111247, Example 1)Show SMILES C[C@@H]1CN(CCN1)c1ccc(cn1)-c1n[nH]c2cnc(nc12)N1[C@@H](C)CCC[C@H]1C |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596223
(CHEMBL5200241)Show SMILES CN1CCC(CC1)n1cc(cn1)-c1cnc(N)c2C(=O)N(CCc12)C1CCCCC1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596221
(CHEMBL5186575)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2CCN(C3CCCCC3)C(=O)c12 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596220
(CHEMBL5205781)Show SMILES Nc1ncc(-c2cnn(c2)C2CCCNC2)c2CCN(C3CCCCC3)C(=O)c12 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM451816
(US10710980, Example 46 | US10947218, Example 46)Show SMILES C[C@@H]1CCCN1Cc1ccc(cc1F)-c1cnc(N)c(c1)C(=O)N[C@H]1CC[C@](C)(O)CC1 |r,wU:24.26,27.30,1.0,wD:27.31,(4.77,-2.71,;6.24,-3.19,;6.71,-4.65,;8.25,-4.65,;8.73,-3.19,;7.48,-2.28,;7.48,-.74,;6.15,.03,;4.81,-.74,;3.48,.03,;3.48,1.57,;4.81,2.34,;6.15,1.57,;7.48,2.34,;2.15,2.34,;2.15,3.88,;.81,4.65,;-.52,3.88,;-1.85,4.65,;-.52,2.34,;.81,1.57,;-1.85,1.57,;-1.85,.03,;-3.19,2.34,;-4.52,1.57,;-4.52,.03,;-5.85,-.74,;-7.19,.03,;-7.96,-1.3,;-8.73,.03,;-7.19,1.57,;-5.85,2.34,)| Show InChI InChI=1S/C25H33FN4O2/c1-16-4-3-11-30(16)15-18-6-5-17(13-22(18)26)19-12-21(23(27)28-14-19)24(31)29-20-7-9-25(2,32)10-8-20/h5-6,12-14,16,20,32H,3-4,7-11,15H2,1-2H3,(H2,27,28)(H,29,31)/t16-,20-,25-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596219
(CHEMBL5189461)Show SMILES Nc1ncc(-c2cnn(CC3CCNCC3)c2)c2CCN(C3CCCCC3)C(=O)c12 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518180
(US11111247, Example 11)Show SMILES CCOC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596225
(CHEMBL5175201)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2CCN(C3C4CC5CC(C4)CC3C5)C(=O)c12 |TLB:29:28:26:22.23.24,THB:24:23:20:27.25.26,24:25:20:22.29.23,19:20:26:22.23.24,29:23:20.28.27:26,(-1.87,-4.78,;-.53,-4.01,;.8,-4.77,;2.13,-4,;2.13,-2.46,;3.46,-1.69,;4.92,-2.15,;5.84,-.9,;4.96,.32,;3.46,-.15,;5.36,1.8,;6.85,2.2,;7.25,3.69,;6.16,4.78,;4.67,4.38,;4.27,2.89,;.8,-1.69,;.8,-.15,;-.53,.62,;-1.87,-.15,;-3.2,.62,;-4.87,1.23,;-4.93,2.67,;-5.81,3.84,;-7.25,3.25,;-7.24,1.71,;-6.26,.64,;-5.67,1.23,;-4.19,1.86,;-4.21,3.4,;-1.87,-1.69,;-3.2,-2.46,;-.53,-2.46,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human)) | BDBM518186
(US11111247, Example 17)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518172
(US11111247, Example 8)Show SMILES C[C@@H]1CN(CCN1)c1ccc(cn1)-c1n[nH]c2cnc(nc12)N1[C@@H](C)CN(C[C@H]1C)C(=O)N(C)C |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596218
(CHEMBL5195236)Show SMILES Nc1ncc(-c2cnn(CC3CCCNC3)c2)c2CCN(C3CCCCC3)C(=O)c12 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Hepcidin
(Homo sapiens) | BDBM518186
(US11111247, Example 17)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1 |r| | PDB
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518170
(US11111247, Example 6)Show SMILES COCC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM518169
(US11111247, Example 5)Show SMILES CC(C)C(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN[C@H](C)C3)c2n1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50594431
(CHEMBL5178082)Show SMILES C[C@@H]1CN(CCN1)c1ccc(cn1)-c1n[nH]c2cnc(nc12)N1CCCCC1C |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human)) | BDBM518194
(US11111247, Example 24)Show SMILES COC(=O)N1C[C@H](C)N([C@H](C)C1)c1ncc2[nH]nc(-c3ccc(nc3)N3CCN(C)CC3)c2n1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human)) | BDBM518173
(US11111247, Example 9)Show SMILES C[C@@H]1CN(CCN1)c1ccc(cn1)-c1n[nH]c2cnc(nc12)N1[C@@H](C)CN(C[C@H]1C)C(=O)N1CCCC1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00206 BindingDB Entry DOI: 10.7270/Q2R78K72 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human)) | BDBM50596220
(CHEMBL5205781)Show SMILES Nc1ncc(-c2cnn(c2)C2CCCNC2)c2CCN(C3CCCCC3)C(=O)c12 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596228
(CHEMBL5197985)Show SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2CCN(C3CCC3)C(=O)c12 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50596208
(CHEMBL5172921)Show SMILES C[C@@H]1CCCN1Cc1ccc(cc1)-c1cnc(N)c2C(=O)N(CCc12)C1CCCCC1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128452 BindingDB Entry DOI: 10.7270/Q2JS9VGJ |
More data for this Ligand-Target Pair | |