Compile Data Set for Download or QSAR

Found 68 hits with Last Name = 'keeton' and Initial = 'ek'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387299 (CHEMBL2048873) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccncc1 |r,w:9.9,c:14| Show InChI InChI=1S/C20H20N4O2S/c21-15-4-2-10-24(12-15)18-14(11-17-19(25)23-20(26)27-17)3-1-5-16(18)13-6-8-22-9-7-13/h1,3,5-9,11,15H,2,4,10,12,21H2,(H,23,25,26)/t15-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387299 (CHEMBL2048873) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccncc1 |r,w:9.9,c:14| Show InChI InChI=1S/C20H20N4O2S/c21-15-4-2-10-24(12-15)18-14(11-17-19(25)23-20(26)27-17)3-1-5-16(18)13-6-8-22-9-7-13/h1,3,5-9,11,15H,2,4,10,12,21H2,(H,23,25,26)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387305 (CHEMBL2046468) Show SMILES N[C@H]1CCN(C1)c1cc(Cl)ccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C14H14ClN3O2S/c15-9-2-1-8(5-12-13(19)17-14(20)21-12)11(6-9)18-4-3-10(16)7-18/h1-2,5-6,10H,3-4,7,16H2,(H,17,19,20)/t10-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387298 (CHEMBL2048872) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccccc1 |r,w:9.9,c:14| Show InChI InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387295 (CHEMBL2048868) Show SMILES COc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:7.6,c:11| Show InChI InChI=1S/C16H19N3O3S/c1-22-12-6-2-4-10(8-13-15(20)18-16(21)23-13)14(12)19-7-3-5-11(17)9-19/h2,4,6,8,11H,3,5,7,9,17H2,1H3,(H,18,20,21)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387308 (CHEMBL2048866) Show SMILES N[C@@H]1CCCN(C1)c1c(Cl)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16ClN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387294 (CHEMBL2048869) Show SMILES CCOc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:8.7,c:12| Show InChI InChI=1S/C17H21N3O3S/c1-2-23-13-7-3-5-11(9-14-16(21)19-17(22)24-14)15(13)20-8-4-6-12(18)10-20/h3,5,7,9,12H,2,4,6,8,10,18H2,1H3,(H,19,21,22)/t12-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387296 (CHEMBL2048870) Show SMILES CC(C)COc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:10.9,c:14| Show InChI InChI=1S/C19H25N3O3S/c1-12(2)11-25-15-7-3-5-13(9-16-18(23)21-19(24)26-16)17(15)22-8-4-6-14(20)10-22/h3,5,7,9,12,14H,4,6,8,10-11,20H2,1-2H3,(H,21,23,24)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387298 (CHEMBL2048872) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccccc1 |r,w:9.9,c:14| Show InChI InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/t16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387309 (CHEMBL2048865) Show SMILES N[C@@H]1CCCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C15H17N3O2S/c16-11-5-3-7-18(9-11)12-6-2-1-4-10(12)8-13-14(19)17-15(20)21-13/h1-2,4,6,8,11H,3,5,7,9,16H2,(H,17,19,20)/t11-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387309 (CHEMBL2048865) Show SMILES N[C@@H]1CCCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C15H17N3O2S/c16-11-5-3-7-18(9-11)12-6-2-1-4-10(12)8-13-14(19)17-15(20)21-13/h1-2,4,6,8,11H,3,5,7,9,16H2,(H,17,19,20)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387310 (CHEMBL2048867) Show SMILES N[C@@H]1CCCN(C1)c1c(Br)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16BrN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387310 (CHEMBL2048867) Show SMILES N[C@@H]1CCCN(C1)c1c(Br)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16BrN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387294 (CHEMBL2048869) Show SMILES CCOc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:8.7,c:12| Show InChI InChI=1S/C17H21N3O3S/c1-2-23-13-7-3-5-11(9-14-16(21)19-17(22)24-14)15(13)20-8-4-6-12(18)10-20/h3,5,7,9,12H,2,4,6,8,10,18H2,1H3,(H,19,21,22)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387295 (CHEMBL2048868) Show SMILES COc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:7.6,c:11| Show InChI InChI=1S/C16H19N3O3S/c1-22-12-6-2-4-10(8-13-15(20)18-16(21)23-13)14(12)19-7-3-5-11(17)9-19/h2,4,6,8,11H,3,5,7,9,17H2,1H3,(H,18,20,21)/t11-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387305 (CHEMBL2046468) Show SMILES N[C@H]1CCN(C1)c1cc(Cl)ccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C14H14ClN3O2S/c15-9-2-1-8(5-12-13(19)17-14(20)21-12)11(6-9)18-4-3-10(16)7-18/h1-2,5-6,10H,3-4,7,16H2,(H,17,19,20)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387309 (CHEMBL2048865) Show SMILES N[C@@H]1CCCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C15H17N3O2S/c16-11-5-3-7-18(9-11)12-6-2-1-4-10(12)8-13-14(19)17-15(20)21-13/h1-2,4,6,8,11H,3,5,7,9,16H2,(H,17,19,20)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387306 (CHEMBL2048864) Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(Cl)c1N1CCNCC1 |w:7.8,t:1| Show InChI InChI=1S/C14H14ClN3O2S/c15-10-3-1-2-9(8-11-13(19)17-14(20)21-11)12(10)18-6-4-16-5-7-18/h1-3,8,16H,4-7H2,(H,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387299 (CHEMBL2048873) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccncc1 |r,w:9.9,c:14| Show InChI InChI=1S/C20H20N4O2S/c21-15-4-2-10-24(12-15)18-14(11-17-19(25)23-20(26)27-17)3-1-5-16(18)13-6-8-22-9-7-13/h1,3,5-9,11,15H,2,4,10,12,21H2,(H,23,25,26)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387308 (CHEMBL2048866) Show SMILES N[C@@H]1CCCN(C1)c1c(Cl)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16ClN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387295 (CHEMBL2048868) Show SMILES COc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:7.6,c:11| Show InChI InChI=1S/C16H19N3O3S/c1-22-12-6-2-4-10(8-13-15(20)18-16(21)23-13)14(12)19-7-3-5-11(17)9-19/h2,4,6,8,11H,3,5,7,9,17H2,1H3,(H,18,20,21)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387308 (CHEMBL2048866) Show SMILES N[C@@H]1CCCN(C1)c1c(Cl)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16ClN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387307 (CHEMBL2048863) Show SMILES N[C@H]1CCN(C1)c1c(Cl)cccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C14H14ClN3O2S/c15-10-3-1-2-8(6-11-13(19)17-14(20)21-11)12(10)18-5-4-9(16)7-18/h1-3,6,9H,4-5,7,16H2,(H,17,19,20)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387306 (CHEMBL2048864) Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(Cl)c1N1CCNCC1 |w:7.8,t:1| Show InChI InChI=1S/C14H14ClN3O2S/c15-10-3-1-2-9(8-11-13(19)17-14(20)21-11)12(10)18-6-4-16-5-7-18/h1-3,8,16H,4-7H2,(H,17,19,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387303 (CHEMBL2048861) Show SMILES OC1=NC(=O)C(S1)=Cc1ccccc1N1CCNCC1 |w:7.8,t:1| Show InChI InChI=1S/C14H15N3O2S/c18-13-12(20-14(19)16-13)9-10-3-1-2-4-11(10)17-7-5-15-6-8-17/h1-4,9,15H,5-8H2,(H,16,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387304 (CHEMBL2048862) Show SMILES N[C@H]1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:12.13,c:18| Show InChI InChI=1S/C14H15N3O2S/c15-10-5-6-17(8-10)11-4-2-1-3-9(11)7-12-13(18)16-14(19)20-12/h1-4,7,10H,5-6,8,15H2,(H,16,18,19)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387303 (CHEMBL2048861) Show SMILES OC1=NC(=O)C(S1)=Cc1ccccc1N1CCNCC1 |w:7.8,t:1| Show InChI InChI=1S/C14H15N3O2S/c18-13-12(20-14(19)16-13)9-10-3-1-2-4-11(10)17-7-5-15-6-8-17/h1-4,9,15H,5-8H2,(H,16,18,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387299 (CHEMBL2048873) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccncc1 |r,w:9.9,c:14| Show InChI InChI=1S/C20H20N4O2S/c21-15-4-2-10-24(12-15)18-14(11-17-19(25)23-20(26)27-17)3-1-5-16(18)13-6-8-22-9-7-13/h1,3,5-9,11,15H,2,4,10,12,21H2,(H,23,25,26)/t15-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387304 (CHEMBL2048862) Show SMILES N[C@H]1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:12.13,c:18| Show InChI InChI=1S/C14H15N3O2S/c15-10-5-6-17(8-10)11-4-2-1-3-9(11)7-12-13(18)16-14(19)20-12/h1-4,7,10H,5-6,8,15H2,(H,16,18,19)/t10-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387297 (CHEMBL2048871) Show SMILES CC(C)Oc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:9.8,c:13| Show InChI InChI=1S/C18H23N3O3S/c1-11(2)24-14-7-3-5-12(9-15-17(22)20-18(23)25-15)16(14)21-8-4-6-13(19)10-21/h3,5,7,9,11,13H,4,6,8,10,19H2,1-2H3,(H,20,22,23)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387301 (CHEMBL2048859) Show SMILES CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |w:14.15,c:20| Show InChI InChI=1S/C16H19N3O2S/c1-18(2)12-7-8-19(10-12)13-6-4-3-5-11(13)9-14-15(20)17-16(21)22-14/h3-6,9,12H,7-8,10H2,1-2H3,(H,17,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387305 (CHEMBL2046468) Show SMILES N[C@H]1CCN(C1)c1cc(Cl)ccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C14H14ClN3O2S/c15-9-2-1-8(5-12-13(19)17-14(20)21-12)11(6-9)18-4-3-10(16)7-18/h1-2,5-6,10H,3-4,7,16H2,(H,17,19,20)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387306 (CHEMBL2048864) Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(Cl)c1N1CCNCC1 |w:7.8,t:1| Show InChI InChI=1S/C14H14ClN3O2S/c15-10-3-1-2-9(8-11-13(19)17-14(20)21-11)12(10)18-6-4-16-5-7-18/h1-3,8,16H,4-7H2,(H,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387309 (CHEMBL2048865) Show SMILES N[C@@H]1CCCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C15H17N3O2S/c16-11-5-3-7-18(9-11)12-6-2-1-4-10(12)8-13-14(19)17-15(20)21-13/h1-2,4,6,8,11H,3,5,7,9,16H2,(H,17,19,20)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387301 (CHEMBL2048859) Show SMILES CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |w:14.15,c:20| Show InChI InChI=1S/C16H19N3O2S/c1-18(2)12-7-8-19(10-12)13-6-4-3-5-11(13)9-14-15(20)17-16(21)22-14/h3-6,9,12H,7-8,10H2,1-2H3,(H,17,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387296 (CHEMBL2048870) Show SMILES CC(C)COc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:10.9,c:14| Show InChI InChI=1S/C19H25N3O3S/c1-12(2)11-25-15-7-3-5-13(9-16-18(23)21-19(24)26-16)17(15)22-8-4-6-14(20)10-22/h3,5,7,9,12,14H,4,6,8,10-11,20H2,1-2H3,(H,21,23,24)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387298 (CHEMBL2048872) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccccc1 |r,w:9.9,c:14| Show InChI InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387310 (CHEMBL2048867) Show SMILES N[C@@H]1CCCN(C1)c1c(Br)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16BrN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387300 (CHEMBL2047864) Show SMILES CCOc1cc(C=C2SC(O)=NC2=O)ccc1O |w:6.5,c:10| Show InChI InChI=1S/C12H11NO4S/c1-2-17-9-5-7(3-4-8(9)14)6-10-11(15)13-12(16)18-10/h3-6,14H,2H2,1H3,(H,13,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387294 (CHEMBL2048869) Show SMILES CCOc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:8.7,c:12| Show InChI InChI=1S/C17H21N3O3S/c1-2-23-13-7-3-5-11(9-14-16(21)19-17(22)24-14)15(13)20-8-4-6-12(18)10-20/h3,5,7,9,12H,2,4,6,8,10,18H2,1H3,(H,19,21,22)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387300 (CHEMBL2047864) Show SMILES CCOc1cc(C=C2SC(O)=NC2=O)ccc1O |w:6.5,c:10| Show InChI InChI=1S/C12H11NO4S/c1-2-17-9-5-7(3-4-8(9)14)6-10-11(15)13-12(16)18-10/h3-6,14H,2H2,1H3,(H,13,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387303 (CHEMBL2048861) Show SMILES OC1=NC(=O)C(S1)=Cc1ccccc1N1CCNCC1 |w:7.8,t:1| Show InChI InChI=1S/C14H15N3O2S/c18-13-12(20-14(19)16-13)9-10-3-1-2-4-11(10)17-7-5-15-6-8-17/h1-4,9,15H,5-8H2,(H,16,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387309 (CHEMBL2048865) Show SMILES N[C@@H]1CCCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:13.14,c:19| Show InChI InChI=1S/C15H17N3O2S/c16-11-5-3-7-18(9-11)12-6-2-1-4-10(12)8-13-14(19)17-15(20)21-13/h1-2,4,6,8,11H,3,5,7,9,16H2,(H,17,19,20)/t11-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387304 (CHEMBL2048862) Show SMILES N[C@H]1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |r,w:12.13,c:18| Show InChI InChI=1S/C14H15N3O2S/c15-10-5-6-17(8-10)11-4-2-1-3-9(11)7-12-13(18)16-14(19)20-12/h1-4,7,10H,5-6,8,15H2,(H,16,18,19)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50372909 (CHEMBL255421) Show SMILES COc1ccc(C=C2SC(O)=NC2=O)cc1OC |w:6.5,c:10| Show InChI InChI=1S/C12H11NO4S/c1-16-8-4-3-7(5-9(8)17-2)6-10-11(14)13-12(15)18-10/h3-6H,1-2H3,(H,13,14,15)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387308 (CHEMBL2048866) Show SMILES N[C@@H]1CCCN(C1)c1c(Cl)cccc1C=C1SC(O)=NC1=O |r,w:14.15,c:20| Show InChI InChI=1S/C15H16ClN3O2S/c16-11-5-1-3-9(7-12-14(20)18-15(21)22-12)13(11)19-6-2-4-10(17)8-19/h1,3,5,7,10H,2,4,6,8,17H2,(H,18,20,21)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387295 (CHEMBL2048868) Show SMILES COc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1 |r,w:7.6,c:11| Show InChI InChI=1S/C16H19N3O3S/c1-22-12-6-2-4-10(8-13-15(20)18-16(21)23-13)14(12)19-7-3-5-11(17)9-19/h2,4,6,8,11H,3,5,7,9,17H2,1H3,(H,18,20,21)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387300 (CHEMBL2047864) Show SMILES CCOc1cc(C=C2SC(O)=NC2=O)ccc1O |w:6.5,c:10| Show InChI InChI=1S/C12H11NO4S/c1-2-17-9-5-7(3-4-8(9)14)6-10-11(15)13-12(16)18-10/h3-6,14H,2H2,1H3,(H,13,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387301 (CHEMBL2048859) Show SMILES CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |w:14.15,c:20| Show InChI InChI=1S/C16H19N3O2S/c1-18(2)12-7-8-19(10-12)13-6-4-3-5-11(13)9-14-15(20)17-16(21)22-14/h3-6,9,12H,7-8,10H2,1-2H3,(H,17,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387299 (CHEMBL2048873) Show SMILES N[C@@H]1CCCN(C1)c1c(C=C2SC(O)=NC2=O)cccc1-c1ccncc1 |r,w:9.9,c:14| Show InChI InChI=1S/C20H20N4O2S/c21-15-4-2-10-24(12-15)18-14(11-17-19(25)23-20(26)27-17)3-1-5-16(18)13-6-8-22-9-7-13/h1,3,5-9,11,15H,2,4,10,12,21H2,(H,23,25,26)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair

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