Compile Data Set for Download or QSAR

Found 329 hits with Last Name = 'kelley' and Initial = 'ja'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50017890 (CHEMBL3289012) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3n(C)ccc3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-18(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-17-8-9-21-19(12-17)10-11-25(21)3/h8-13,18,26H,4-7,14-16H2,1-3H3/b20-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017890 (CHEMBL3289012) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3n(C)ccc3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-18(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-17-8-9-21-19(12-17)10-11-25(21)3/h8-13,18,26H,4-7,14-16H2,1-3H3/b20-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017892 (CHEMBL3289014) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccc3ccn(C)c23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-7-18(8-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-19-10-6-9-17-11-12-25(3)21(17)19/h6,9-13,18,26H,4-5,7-8,14-16H2,1-3H3/b20-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017891 (CHEMBL3289013) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccn(C)c3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-19(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)12-17-8-9-18-10-11-25(3)21(18)13-17/h8-13,19,26H,4-7,14-16H2,1-3H3/b20-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50017892 (CHEMBL3289014) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccc3ccn(C)c23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-7-18(8-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-19-10-6-9-17-11-12-25(3)21(17)19/h6,9-13,18,26H,4-5,7-8,14-16H2,1-3H3/b20-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50017891 (CHEMBL3289013) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccn(C)c3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-19(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)12-17-8-9-18-10-11-25(3)21(18)13-17/h8-13,19,26H,4-7,14-16H2,1-3H3/b20-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017889 (CHEMBL3289011) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccc3n(C)ccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-7-17(8-5-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-18-9-6-10-21-20(18)11-12-25(21)3/h6,9-13,17,26H,4-5,7-8,14-16H2,1-3H3/b19-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50017889 (CHEMBL3289011) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccc3n(C)ccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-7-17(8-5-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-18-9-6-10-21-20(18)11-12-25(21)3/h6,9-13,17,26H,4-5,7-8,14-16H2,1-3H3/b19-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244866 (CHEMBL511820 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...) Show SMILES CN(C)c1ccccc1C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)19-6-4-3-5-18(19)21(27)30-14-22(13-25)12-16(20(26)31-22)11-15-7-9-17(10-8-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244416 (CHEMBL527875 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)c(Br)c2)C(=O)O1 Show InChI InChI=1S/C21H26BrFO5/c1-3-5-6-15(4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-18(23)17(22)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244416 (CHEMBL527875 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)c(Br)c2)C(=O)O1 Show InChI InChI=1S/C21H26BrFO5/c1-3-5-6-15(4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-18(23)17(22)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50017890 (CHEMBL3289012) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3n(C)ccc3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-18(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-17-8-9-21-19(12-17)10-11-25(21)3/h8-13,18,26H,4-7,14-16H2,1-3H3/b20-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserine				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50245091 (CHEMBL519398 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...) Show SMILES OCC1(COC(=O)c2ccc(cc2)[N+]([O-])=O)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C20H16N2O9/c23-11-20(12-30-18(24)14-3-7-17(8-4-14)22(28)29)10-15(19(25)31-20)9-13-1-5-16(6-2-13)21(26)27/h1-9,23H,10-12H2/b15-9+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244865 (CHEMBL471153 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...) Show SMILES CN(C)c1cccc(c1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)19-5-3-4-16(11-19)20(26)30-14-22(13-25)12-17(21(27)31-22)10-15-6-8-18(9-7-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b17-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244693 (CHEMBL516638 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)c(Cl)c2)C(=O)O1 Show InChI InChI=1S/C21H26ClFO5/c1-3-5-15(6-4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-18(23)17(22)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244693 (CHEMBL516638 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)c(Cl)c2)C(=O)O1 Show InChI InChI=1S/C21H26ClFO5/c1-3-5-15(6-4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-18(23)17(22)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244961 (CHEMBL472520 | rac-(E/Z)-(4-heptylidene-2-(hydroxy...) Show SMILES CCCCCC\C=C1\CC(CO)(COC(=O)c2c(cc(cc2C(C)C)C(C)C)C(C)C)OC1=O Show InChI InChI=1S/C29H44O5/c1-8-9-10-11-12-13-22-16-29(17-30,34-27(22)31)18-33-28(32)26-24(20(4)5)14-23(19(2)3)15-25(26)21(6)7/h13-15,19-21,30H,8-12,16-18H2,1-7H3/b22-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244961 (CHEMBL472520 | rac-(E/Z)-(4-heptylidene-2-(hydroxy...) Show SMILES CCCCCC\C=C1\CC(CO)(COC(=O)c2c(cc(cc2C(C)C)C(C)C)C(C)C)OC1=O Show InChI InChI=1S/C29H44O5/c1-8-9-10-11-12-13-22-16-29(17-30,34-27(22)31)18-33-28(32)26-24(20(4)5)14-23(19(2)3)15-25(26)21(6)7/h13-15,19-21,30H,8-12,16-18H2,1-7H3/b22-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244413 (CHEMBL488498 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)c(Br)c2)C(=O)O1 Show InChI InChI=1S/C21H26BrFO5/c1-3-5-15(6-4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-18(23)17(22)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244413 (CHEMBL488498 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)c(Br)c2)C(=O)O1 Show InChI InChI=1S/C21H26BrFO5/c1-3-5-15(6-4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-18(23)17(22)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244414 (CHEMBL488500 | rac-(E)-{4-[(4-Chlorophenyl)methyle...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C/c2ccc(Cl)cc2)C(=O)O1 Show InChI InChI=1S/C21H27ClO5/c1-3-5-6-16(4-2)19(24)26-14-21(13-23)12-17(20(25)27-21)11-15-7-9-18(22)10-8-15/h7-11,16,23H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244414 (CHEMBL488500 | rac-(E)-{4-[(4-Chlorophenyl)methyle...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C/c2ccc(Cl)cc2)C(=O)O1 Show InChI InChI=1S/C21H27ClO5/c1-3-5-6-16(4-2)19(24)26-14-21(13-23)12-17(20(25)27-21)11-15-7-9-18(22)10-8-15/h7-11,16,23H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244648 (CHEMBL453598 | rac-(E)-(2-(Hydroxymethyl)-5-oxo-4-...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)C(F)(F)F)C(=O)O1 Show InChI InChI=1S/C22H27F3O5/c1-3-5-16(6-4-2)19(27)29-14-21(13-26)12-17(20(28)30-21)11-15-7-9-18(10-8-15)22(23,24)25/h7-11,16,26H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244648 (CHEMBL453598 | rac-(E)-(2-(Hydroxymethyl)-5-oxo-4-...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)C(F)(F)F)C(=O)O1 Show InChI InChI=1S/C22H27F3O5/c1-3-5-16(6-4-2)19(27)29-14-21(13-26)12-17(20(28)30-21)11-15-7-9-18(10-8-15)22(23,24)25/h7-11,16,26H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50245049 (CHEMBL488706 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C21H27NO7/c1-3-5-6-16(4-2)19(24)28-14-21(13-23)12-17(20(25)29-21)11-15-7-9-18(10-8-15)22(26)27/h7-11,16,23H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244740 (CHEMBL461372 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(Cl)c(F)c2)C(=O)O1 Show InChI InChI=1S/C21H26ClFO5/c1-3-5-15(6-4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-17(22)18(23)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244740 (CHEMBL461372 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(Cl)c(F)c2)C(=O)O1 Show InChI InChI=1S/C21H26ClFO5/c1-3-5-15(6-4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-17(22)18(23)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244908 (CHEMBL511301 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...) Show SMILES COc1ccc(\C=C2/CC(CO)(COC(=O)c3c(C)cc(C)cc3C)OC2=O)cc1 Show InChI InChI=1S/C24H26O6/c1-15-9-16(2)21(17(3)10-15)23(27)29-14-24(13-25)12-19(22(26)30-24)11-18-5-7-20(28-4)8-6-18/h5-11,25H,12-14H2,1-4H3/b19-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244908 (CHEMBL511301 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...) Show SMILES COc1ccc(\C=C2/CC(CO)(COC(=O)c3c(C)cc(C)cc3C)OC2=O)cc1 Show InChI InChI=1S/C24H26O6/c1-15-9-16(2)21(17(3)10-15)23(27)29-14-24(13-25)12-19(22(26)30-24)11-18-5-7-20(28-4)8-6-18/h5-11,25H,12-14H2,1-4H3/b19-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244482 ((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)18-9-5-16(6-10-18)20(26)30-14-22(13-25)12-17(21(27)31-22)11-15-3-7-19(8-4-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b17-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244915 (CHEMBL472002 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...) Show SMILES CN(C)c1ccccc1C(=O)OCC1(CO)C\C(=C/c2cccc(c2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)19-9-4-3-8-18(19)21(27)30-14-22(13-25)12-16(20(26)31-22)10-15-6-5-7-17(11-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b16-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244643 (CHEMBL452307 | rac-(E)-(4-{[4-(Dimethylamino)pheny...) Show SMILES CN(C)c1ccc(\C=C2/CC(CO)(COC(=O)c3ccc(cc3)N(C)C)OC2=O)cc1 Show InChI InChI=1S/C24H28N2O5/c1-25(2)20-9-5-17(6-10-20)13-19-14-24(15-27,31-23(19)29)16-30-22(28)18-7-11-21(12-8-18)26(3)4/h5-13,27H,14-16H2,1-4H3/b19-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244863 (CHEMBL472362 | rac-(E)-{4-[(4-Chloro-3-fluoropheny...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C/c2ccc(Cl)c(F)c2)C(=O)O1 Show InChI InChI=1S/C21H26ClFO5/c1-3-5-6-15(4-2)19(25)27-13-21(12-24)11-16(20(26)28-21)9-14-7-8-17(22)18(23)10-14/h7-10,15,24H,3-6,11-13H2,1-2H3/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50204623 (CHEMBL223747 | [2-(hydroxymethyl)-4-(methylethylid...) Show SMILES [#6]\[#6](-[#6])=[#6]-1/[#6]C([#6]-[#8])([#6]-[#8]-[#6](=O)-c2ccc(cc2)C#Cc2ccc(cc2)C#C)[#8]-[#6]-1=O Show InChI InChI=1S/C26H22O5/c1-4-19-5-7-20(8-6-19)9-10-21-11-13-22(14-12-21)24(28)30-17-26(16-27)15-23(18(2)3)25(29)31-26/h1,5-8,11-14,27H,15-17H2,2-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCalpha				J Med Chem 50: 962-78 (2007) Article DOI: 10.1021/jm061289j BindingDB Entry DOI: 10.7270/Q22R3SGR
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244914 (CHEMBL472001 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...) Show SMILES CN(C)c1cccc(c1)C(=O)OCC1(CO)C\C(=C/c2cccc(c2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)18-7-4-6-16(11-18)20(26)30-14-22(13-25)12-17(21(27)31-22)9-15-5-3-8-19(10-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b17-9+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244690 (CHEMBL358095 | rac-(E)-{4-[(4-Fluorophenyl)methyle...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)cc2)C(=O)O1 Show InChI InChI=1S/C21H27FO5/c1-3-5-16(6-4-2)19(24)26-14-21(13-23)12-17(20(25)27-21)11-15-7-9-18(22)10-8-15/h7-11,16,23H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244690 (CHEMBL358095 | rac-(E)-{4-[(4-Fluorophenyl)methyle...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc(F)cc2)C(=O)O1 Show InChI InChI=1S/C21H27FO5/c1-3-5-16(6-4-2)19(24)26-14-21(13-23)12-17(20(25)27-21)11-15-7-9-18(22)10-8-15/h7-11,16,23H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50204626 ((2-(hydroxymethyl)-5-oxo-4-(propan-2-ylidene)-tetr...) Show SMILES [#6]-[#8]-c1ccc(cc1)C#Cc1ccc(cc1)C#Cc1ccc(cc1)-[#6](=O)-[#8]-[#6]C1([#6]-[#8])[#6]\[#6](=[#6](/[#6])-[#6])-[#6](=O)-[#8]1 Show InChI InChI=1S/C33H28O6/c1-23(2)30-20-33(21-34,39-32(30)36)22-38-31(35)28-16-12-26(13-17-28)10-8-24-4-6-25(7-5-24)9-11-27-14-18-29(37-3)19-15-27/h4-7,12-19,34H,20-22H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCalpha				J Med Chem 50: 962-78 (2007) Article DOI: 10.1021/jm061289j BindingDB Entry DOI: 10.7270/Q22R3SGR
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50017891 (CHEMBL3289013) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccn(C)c3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-19(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)12-17-8-9-18-10-11-25(3)21(18)13-17/h8-13,19,26H,4-7,14-16H2,1-3H3/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human PKC-alpha after 5 mins by scintillation counting analysis in presence of phosphatidylserine				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244554 (CHEMBL508402 | rac-(E)-{4-[(4-Chloro-3-fluoropheny...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/c2ccc(Cl)c(F)c2)C(=O)O1 Show InChI InChI=1S/C18H20ClFO5/c1-17(2,3)16(23)24-10-18(9-21)8-12(15(22)25-18)6-11-4-5-13(19)14(20)7-11/h4-7,21H,8-10H2,1-3H3/b12-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244909 (CHEMBL471137 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...) Show SMILES COc1ccc(\C=C2/CC(CO)(COC(=O)c3c(cc(cc3C(C)C)C(C)C)C(C)C)OC2=O)cc1 Show InChI InChI=1S/C30H38O6/c1-18(2)22-13-25(19(3)4)27(26(14-22)20(5)6)29(33)35-17-30(16-31)15-23(28(32)36-30)12-21-8-10-24(34-7)11-9-21/h8-14,18-20,31H,15-17H2,1-7H3/b23-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244909 (CHEMBL471137 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...) Show SMILES COc1ccc(\C=C2/CC(CO)(COC(=O)c3c(cc(cc3C(C)C)C(C)C)C(C)C)OC2=O)cc1 Show InChI InChI=1S/C30H38O6/c1-18(2)22-13-25(19(3)4)27(26(14-22)20(5)6)29(33)35-17-30(16-31)15-23(28(32)36-30)12-21-8-10-24(34-7)11-9-21/h8-14,18-20,31H,15-17H2,1-7H3/b23-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244867 (CHEMBL472171 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cccc(c2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)18-8-6-16(7-9-18)20(26)30-14-22(13-25)12-17(21(27)31-22)10-15-4-3-5-19(11-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b17-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50017891 (CHEMBL3289013) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccn(C)c3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-19(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)12-17-8-9-18-10-11-25(3)21(18)13-17/h8-13,19,26H,4-7,14-16H2,1-3H3/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserine				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50017890 (CHEMBL3289012) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3n(C)ccc3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-18(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-17-8-9-21-19(12-17)10-11-25(21)3/h8-13,18,26H,4-7,14-16H2,1-3H3/b20-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant human PKC-alpha after 5 mins by scintillation counting analysis in presence of phosphatidylserine				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
Protein kinase C alpha type (MOUSE)	BDBM50244861 (CHEMBL512019 | rac-(E/Z)-(4-(4-bromobenzylidene)-2...) Show SMILES CCCCC(CC)C(=O)OCC1(CO)C\C(=C\c2ccc(Br)cc2)C(=O)O1 Show InChI InChI=1S/C21H27BrO5/c1-3-5-6-16(4-2)19(24)26-14-21(13-23)12-17(20(25)27-21)11-15-7-9-18(22)10-8-15/h7-11,16,23H,3-6,12-14H2,1-2H3/b17-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244971 (CHEMBL471317 | rac-(E)-{2-(Hydroxymethyl)-4-[(2-ni...) Show SMILES CN(C)c1ccccc1C(=O)OCC1(CO)C\C(=C/c2ccccc2[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)19-10-6-4-8-17(19)21(27)30-14-22(13-25)12-16(20(26)31-22)11-15-7-3-5-9-18(15)24(28)29/h3-11,25H,12-14H2,1-2H3/b16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Binding affinity to RasGRP3 (unknown origin)				J Med Chem 51: 5198-220 (2008) Article DOI: 10.1021/jm8001907 BindingDB Entry DOI: 10.7270/Q2G44Q4B
					More data for this Ligand-Target Pair

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