Compile Data Set for Download or QSAR

Found 605 hits with Last Name = 'kitade' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM126083 (US8779142, 102) Show SMILES CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O Show InChI InChI=1S/C25H26N8O/c1-5-16-10-17(24(26)34)6-7-20(16)33-25-22(23(30-33)15(2)3)21(8-9-27-25)32-13-19(28-14-32)18-11-29-31(4)12-18/h6-15H,5H2,1-4H3,(H2,26,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human HSP90-beta by fluorescence polarization competitive binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM126083 (US8779142, 102) Show SMILES CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O Show InChI InChI=1S/C25H26N8O/c1-5-16-10-17(24(26)34)6-7-20(16)33-25-22(23(30-33)15(2)3)21(8-9-27-25)32-13-19(28-14-32)18-11-29-31(4)12-18/h6-15H,5H2,1-4H3,(H2,26,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs followed by FITC-GDA addition and measured after 5 hrs by fluorescence polari...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50582399 (CHEMBL5094983) Show SMILES NC(=O)c1ccc(cc1NC1CCC(O)CC1)-c1nccc2c(ccnc12)-n1cnc(c1)-c1ccccc1 |(-1.67,-8.76,;-.34,-7.99,;1,-8.76,;-.34,-6.45,;-1.67,-5.69,;-1.67,-4.14,;-.34,-3.37,;.99,-4.14,;.99,-5.68,;2.32,-6.45,;3.66,-5.68,;3.66,-4.14,;4.99,-3.37,;6.32,-4.14,;7.66,-3.37,;6.32,-5.68,;4.99,-6.45,;-.34,-1.83,;1,-1.06,;.99,.48,;-.34,1.25,;-1.67,.48,;-3.01,1.25,;-4.33,.47,;-4.33,-1.05,;-3,-1.82,;-1.67,-1.06,;-3.01,2.79,;-1.88,3.82,;-2.5,5.24,;-4,5.09,;-4.34,3.56,;-5.08,6.18,;-6.57,5.78,;-7.66,6.87,;-7.26,8.36,;-5.78,8.76,;-4.68,7.68,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs followed by FITC-GDA addition and measured after 5 hrs by fluorescence polari...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM50582399 (CHEMBL5094983) Show SMILES NC(=O)c1ccc(cc1NC1CCC(O)CC1)-c1nccc2c(ccnc12)-n1cnc(c1)-c1ccccc1 |(-1.67,-8.76,;-.34,-7.99,;1,-8.76,;-.34,-6.45,;-1.67,-5.69,;-1.67,-4.14,;-.34,-3.37,;.99,-4.14,;.99,-5.68,;2.32,-6.45,;3.66,-5.68,;3.66,-4.14,;4.99,-3.37,;6.32,-4.14,;7.66,-3.37,;6.32,-5.68,;4.99,-6.45,;-.34,-1.83,;1,-1.06,;.99,.48,;-.34,1.25,;-1.67,.48,;-3.01,1.25,;-4.33,.47,;-4.33,-1.05,;-3,-1.82,;-1.67,-1.06,;-3.01,2.79,;-1.88,3.82,;-2.5,5.24,;-4,5.09,;-4.34,3.56,;-5.08,6.18,;-6.57,5.78,;-7.66,6.87,;-7.26,8.36,;-5.78,8.76,;-4.68,7.68,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human HSP90-beta by fluorescence polarization competitive binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Endoplasmin (Homo sapiens (Human))	BDBM126083 (US8779142, 102) Show SMILES CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O Show InChI InChI=1S/C25H26N8O/c1-5-16-10-17(24(26)34)6-7-20(16)33-25-22(23(30-33)15(2)3)21(8-9-27-25)32-13-19(28-14-32)18-11-29-31(4)12-18/h6-15H,5H2,1-4H3,(H2,26,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to GRP94 (unknown origin) by fluorescence polarization competitive binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Heat shock protein 75 kDa, mitochondrial (Homo sapiens (Human))	BDBM126083 (US8779142, 102) Show SMILES CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O Show InChI InChI=1S/C25H26N8O/c1-5-16-10-17(24(26)34)6-7-20(16)33-25-22(23(30-33)15(2)3)21(8-9-27-25)32-13-19(28-14-32)18-11-29-31(4)12-18/h6-15H,5H2,1-4H3,(H2,26,34)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to TRAP1 (unknown origin) by fluorescence polarization competitive binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Endoplasmin (Homo sapiens (Human))	BDBM50582399 (CHEMBL5094983) Show SMILES NC(=O)c1ccc(cc1NC1CCC(O)CC1)-c1nccc2c(ccnc12)-n1cnc(c1)-c1ccccc1 |(-1.67,-8.76,;-.34,-7.99,;1,-8.76,;-.34,-6.45,;-1.67,-5.69,;-1.67,-4.14,;-.34,-3.37,;.99,-4.14,;.99,-5.68,;2.32,-6.45,;3.66,-5.68,;3.66,-4.14,;4.99,-3.37,;6.32,-4.14,;7.66,-3.37,;6.32,-5.68,;4.99,-6.45,;-.34,-1.83,;1,-1.06,;.99,.48,;-.34,1.25,;-1.67,.48,;-3.01,1.25,;-4.33,.47,;-4.33,-1.05,;-3,-1.82,;-1.67,-1.06,;-3.01,2.79,;-1.88,3.82,;-2.5,5.24,;-4,5.09,;-4.34,3.56,;-5.08,6.18,;-6.57,5.78,;-7.66,6.87,;-7.26,8.36,;-5.78,8.76,;-4.68,7.68,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to GRP94 (unknown origin) by fluorescence polarization competitive binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
Heat shock protein 75 kDa, mitochondrial (Homo sapiens (Human))	BDBM50582399 (CHEMBL5094983) Show SMILES NC(=O)c1ccc(cc1NC1CCC(O)CC1)-c1nccc2c(ccnc12)-n1cnc(c1)-c1ccccc1 |(-1.67,-8.76,;-.34,-7.99,;1,-8.76,;-.34,-6.45,;-1.67,-5.69,;-1.67,-4.14,;-.34,-3.37,;.99,-4.14,;.99,-5.68,;2.32,-6.45,;3.66,-5.68,;3.66,-4.14,;4.99,-3.37,;6.32,-4.14,;7.66,-3.37,;6.32,-5.68,;4.99,-6.45,;-.34,-1.83,;1,-1.06,;.99,.48,;-.34,1.25,;-1.67,.48,;-3.01,1.25,;-4.33,.47,;-4.33,-1.05,;-3,-1.82,;-1.67,-1.06,;-3.01,2.79,;-1.88,3.82,;-2.5,5.24,;-4,5.09,;-4.34,3.56,;-5.08,6.18,;-6.57,5.78,;-7.66,6.87,;-7.26,8.36,;-5.78,8.76,;-4.68,7.68,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to TRAP1 (unknown origin) by fluorescence polarization competitive binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01715 BindingDB Entry DOI: 10.7270/Q2Z323H2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320967 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES CS(=O)(=O)c1ccccc1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 Show InChI InChI=1S/C20H22N6O7S2/c1-34(29,30)14-5-3-2-4-11(14)6-7-12-9-26(19-15(12)18(21)23-10-24-19)20-17(28)16(27)13(33-20)8-25-35(22,31)32/h2-5,9-10,13,16-17,20,25,27-28H,8H2,1H3,(H2,21,23,24)(H2,22,31,32)/t13-,16-,17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320956 (4-Amino-5-[2-(2,6-difluorophenyl)ethynyl]-7-[(2R,3...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cccc3F)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C19H18F2N6O5S/c20-11-2-1-3-12(21)10(11)5-4-9-7-27(18-14(9)17(22)24-8-25-18)19-16(29)15(28)13(32-19)6-26-33(23,30)31/h1-3,7-8,13,15-16,19,26,28-29H,6H2,(H2,22,24,25)(H2,23,30,31)/t13-,15-,16-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320969 (4-Amino-5-[2-(4-amino-2,6-difluoro-phenyl)ethynyl]...) Show SMILES Nc1cc(F)c(C#Cc2cn([C@@H]3O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)c(F)c1 Show InChI InChI=1S/C19H19F2N7O5S/c20-11-3-9(22)4-12(21)10(11)2-1-8-6-28(18-14(8)17(23)25-7-26-18)19-16(30)15(29)13(33-19)5-27-34(24,31)32/h3-4,6-7,13,15-16,19,27,29-30H,5,22H2,(H2,23,25,26)(H2,24,31,32)/t13-,15-,16-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320974 (4-Amino-5-[2-[2,6-difluoro-4-(2-oxopyrrolidin-1-yl...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCCC3=O)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C23H23F2N7O6S/c24-14-6-12(31-5-1-2-17(31)33)7-15(25)13(14)4-3-11-9-32(22-18(11)21(26)28-10-29-22)23-20(35)19(34)16(38-23)8-30-39(27,36)37/h6-7,9-10,16,19-20,23,30,34-35H,1-2,5,8H2,(H2,26,28,29)(H2,27,36,37)/t16-,19-,20-,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320968 (4-[4-[2-[4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCOCC3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C23H25F2N7O6S/c24-15-7-13(31-3-5-37-6-4-31)8-16(25)14(15)2-1-12-10-32(22-18(12)21(26)28-11-29-22)23-20(34)19(33)17(38-23)9-30-39(27,35)36/h7-8,10-11,17,19-20,23,30,33-34H,3-6,9H2,(H2,26,28,29)(H2,27,35,36)/t17-,19-,20-,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321049 (US10174040, Example 132 | [(2R,3S,4R,5R)-5-[4-Amin...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cccc3F)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |$_AV:;4;3;2;1;7a;7;6;5;1;2;1;6;;5;4;3;2;;4a;5;1;2;1;;;;;;3;;4;$| Show InChI InChI=1S/C19H17F2N5O6S/c20-11-2-1-3-12(21)10(11)5-4-9-6-26(18-14(9)17(22)24-8-25-18)19-16(28)15(27)13(32-19)7-31-33(23,29)30/h1-3,6,8,13,15-16,19,27-28H,7H2,(H2,22,24,25)(H2,23,29,30)/t13-,15-,16-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321048 (US10174040, Example 131 | [(2R,3S,4R,5R)-5-[4-amin...) Show SMILES Nc1ncnc2n(cc(C#Cc3ccccc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O |$_AV:;4;3;2;1;7a;7;6;5;1;2;1;2;3;4;5;6;4a;5;1;2;1;;;;;;3;;4;$| Show InChI InChI=1S/C19H19N5O6S/c20-17-14-12(7-6-11-4-2-1-3-5-11)8-24(18(14)23-10-22-17)19-16(26)15(25)13(30-19)9-29-31(21,27)28/h1-5,8,10,13,15-16,19,25-26H,9H2,(H2,20,22,23)(H2,21,27,28)/t13-,15-,16-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321046 (4-Amino-7-[(1R,4R,5S)-4,5-dihydroxy-3-[(sulfamoyla...) Show SMILES CCOc1cccc(F)c1C#Cc1cn([C@@H]2C=C(CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 |t:17| Show InChI InChI=1S/C22H23FN6O5S/c1-2-34-17-5-3-4-15(23)14(17)7-6-12-10-29(22-18(12)21(24)26-11-27-22)16-8-13(19(30)20(16)31)9-28-35(25,32)33/h3-5,8,10-11,16,19-20,28,30-31H,2,9H2,1H3,(H2,24,26,27)(H2,25,32,33)/t16-,19-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321034 (4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamo...) Show SMILES CCS(=O)(=O)c1cc(cc(F)c1C#Cc1cn([C@@H]2C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12)N1CCCC1 Show InChI InChI=1S/C26H32FN7O6S2/c1-2-41(37,38)21-11-17(33-7-3-4-8-33)10-19(27)18(21)6-5-15-13-34(26-22(15)25(28)30-14-31-26)20-9-16(23(35)24(20)36)12-32-42(29,39)40/h10-11,13-14,16,20,23-24,32,35-36H,2-4,7-9,12H2,1H3,(H2,28,30,31)(H2,29,39,40)/t16-,20-,23-,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320979 (4-Amino-5-[2-[2,6-difluoro-4-(3-hydroxyazetidin-1-...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CC(O)C3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C22H23F2N7O6S/c23-14-3-11(30-7-12(32)8-30)4-15(24)13(14)2-1-10-6-31(21-17(10)20(25)27-9-28-21)22-19(34)18(33)16(37-22)5-29-38(26,35)36/h3-4,6,9,12,16,18-19,22,29,32-34H,5,7-8H2,(H2,25,27,28)(H2,26,35,36)/t16-,18-,19-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320980 (4-Amino-5-[2-[2,6-difluoro-4-[(3R)-3-hydroxy-1-pip...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCC[C@@H](O)C3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H27F2N7O6S/c25-16-6-13(32-5-1-2-14(34)10-32)7-17(26)15(16)4-3-12-9-33(23-19(12)22(27)29-11-30-23)24-21(36)20(35)18(39-24)8-31-40(28,37)38/h6-7,9,11,14,18,20-21,24,31,34-36H,1-2,5,8,10H2,(H2,27,29,30)(H2,28,37,38)/t14-,18-,20-,21-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320981 (1-[4-[2-[4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCC(C3)C(O)=O)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O |$_AV:;4;3;2;1;7a;7;6;5;2;1;4;5;;6;1;2;3;;1;5;4;3;2;;;;4a;2;1;5;1;;;;;;4;;3;$| Show InChI InChI=1S/C24H25F2N7O7S/c25-15-5-13(32-4-3-12(8-32)24(36)37)6-16(26)14(15)2-1-11-9-33(22-18(11)21(27)29-10-30-22)23-20(35)19(34)17(40-23)7-31-41(28,38)39/h5-6,9-10,12,17,19-20,23,31,34-35H,3-4,7-8H2,(H,36,37)(H2,27,29,30)(H2,28,38,39)/t12?,17-,19-,20-,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320991 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 Show InChI InChI=1S/C21H23FN6O6S/c1-2-33-14-5-3-4-13(22)12(14)7-6-11-9-28(20-16(11)19(23)25-10-26-20)21-18(30)17(29)15(34-21)8-27-35(24,31)32/h3-5,9-10,15,17-18,21,27,29-30H,2,8H2,1H3,(H2,23,25,26)(H2,24,31,32)/t15-,17-,18-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320994 (Methyl 4-[2-[4-amino-7-[(2R,3R,4S,5R)-3,4-dihydrox...) Show SMILES COC(=O)c1cc(F)c(C#Cc2cn([C@@H]3O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)c(F)c1 |$_AV:;;;;1;6;5;;4;1;2;5;6;7;2;1;5;1;;;;;;4;;3;;7a;1;2;3;4;;4a;3;;2$| Show InChI InChI=1S/C21H20F2N6O7S/c1-35-21(32)10-4-12(22)11(13(23)5-10)3-2-9-7-29(19-15(9)18(24)26-8-27-19)20-17(31)16(30)14(36-20)6-28-37(25,33)34/h4-5,7-8,14,16-17,20,28,30-31H,6H2,1H3,(H2,24,26,27)(H2,25,33,34)/t14-,16-,17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321007 (4-[4-[2-[4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCS(=O)(=O)CC3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C23H25F2N7O7S2/c24-15-7-13(31-3-5-40(35,36)6-4-31)8-16(25)14(15)2-1-12-10-32(22-18(12)21(26)28-11-29-22)23-20(34)19(33)17(39-23)9-30-41(27,37)38/h7-8,10-11,17,19-20,23,30,33-34H,3-6,9H2,(H2,26,28,29)(H2,27,37,38)/t17-,19-,20-,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321008 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES CCS(=O)(=O)c1cc(cc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12)N1CC[C@@H](F)C1 Show InChI InChI=1S/C25H29F2N7O7S2/c1-2-42(37,38)19-8-15(33-6-5-14(26)11-33)7-17(27)16(19)4-3-13-10-34(24-20(13)23(28)30-12-31-24)25-22(36)21(35)18(41-25)9-32-43(29,39)40/h7-8,10,12,14,18,21-22,25,32,35-36H,2,5-6,9,11H2,1H3,(H2,28,30,31)(H2,29,39,40)/t14-,18-,21-,22-,25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321033 (4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamo...) Show SMILES COc1ccc(C#Cc2cn([C@@H]3C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)c(c1)S(C)(=O)=O Show InChI InChI=1S/C22H26N6O7S2/c1-35-15-6-5-12(17(8-15)36(2,31)32)3-4-13-10-28(22-18(13)21(23)25-11-26-22)16-7-14(19(29)20(16)30)9-27-37(24,33)34/h5-6,8,10-11,14,16,19-20,27,29-30H,7,9H2,1-2H3,(H2,23,25,26)(H2,24,33,34)/t14-,16-,19-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321010 (2-[2-[4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(s...) Show SMILES NC(=O)c1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 |$_AV:;;;1;6;5;4;3;;2;1;2;5;6;7;2;1;5;1;;;;;;4;;3;;7a;1;2;3;4;;4a$| Show InChI InChI=1S/C20H20FN7O6S/c21-12-3-1-2-11(18(23)31)10(12)5-4-9-7-28(19-14(9)17(22)25-8-26-19)20-16(30)15(29)13(34-20)6-27-35(24,32)33/h1-3,7-8,13,15-16,20,27,29-30H,6H2,(H2,23,31)(H2,22,25,26)(H2,24,32,33)/t13-,15-,16-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321045 (4-Amino-5-[2-(2,6-difluorophenyl)ethynyl]-7-[(1R,4...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cccc3F)c12)[C@@H]1C=C(CNS(N)(=O)=O)[C@@H](O)[C@H]1O |t:24| Show InChI InChI=1S/C20H18F2N6O4S/c21-13-2-1-3-14(22)12(13)5-4-10-8-28(20-16(10)19(23)25-9-26-20)15-6-11(17(29)18(15)30)7-27-33(24,31)32/h1-3,6,8-9,15,17-18,27,29-30H,7H2,(H2,23,25,26)(H2,24,31,32)/t15-,17-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320988 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES COc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 Show InChI InChI=1S/C20H21FN6O6S/c1-32-13-4-2-3-12(21)11(13)6-5-10-8-27(19-15(10)18(22)24-9-25-19)20-17(29)16(28)14(33-20)7-26-34(23,30)31/h2-4,8-9,14,16-17,20,26,28-29H,7H2,1H3,(H2,22,24,25)(H2,23,30,31)/t14-,16-,17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320978 (4-Amino-5-[2-[2,6-difluoro-4-(3-hydroxy-1-piperidy...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCCC(O)C3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H27F2N7O6S/c25-16-6-13(32-5-1-2-14(34)10-32)7-17(26)15(16)4-3-12-9-33(23-19(12)22(27)29-11-30-23)24-21(36)20(35)18(39-24)8-31-40(28,37)38/h6-7,9,11,14,18,20-21,24,31,34-36H,1-2,5,8,10H2,(H2,27,29,30)(H2,28,37,38)/t14?,18-,20-,21-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320997 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cccc3OCC(F)(F)F)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C21H20F4N6O6S/c22-12-2-1-3-13(36-8-21(23,24)25)11(12)5-4-10-7-31(19-15(10)18(26)28-9-29-19)20-17(33)16(32)14(37-20)6-30-38(27,34)35/h1-3,7,9,14,16-17,20,30,32-33H,6,8H2,(H2,26,28,29)(H2,27,34,35)/t14-,16-,17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321035 (4-Amino-5-[2-[2,6-difluoro-4-[(3R)-3-fluoropyrroli...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CC[C@@H](F)C3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H26F3N7O4S/c25-14-3-4-33(10-14)15-6-17(26)16(18(27)7-15)2-1-12-9-34(24-20(12)23(28)30-11-31-24)19-5-13(21(35)22(19)36)8-32-39(29,37)38/h6-7,9,11,13-14,19,21-22,32,35-36H,3-5,8,10H2,(H2,28,30,31)(H2,29,37,38)/t13-,14-,19-,21-,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321047 (4-Amino-7-[(1R,4R,5S)-4,5-dihydroxy-3-[(sulfamoyla...) Show SMILES CSc1cccc(F)c1C#Cc1cn([C@@H]2C=C(CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 |t:16| Show InChI InChI=1S/C21H21FN6O4S2/c1-33-16-4-2-3-14(22)13(16)6-5-11-9-28(21-17(11)20(23)25-10-26-21)15-7-12(18(29)19(15)30)8-27-34(24,31)32/h2-4,7,9-10,15,18-19,27,29-30H,8H2,1H3,(H2,23,25,26)(H2,24,31,32)/t15-,18-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320976 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES CCOc1cc(F)cc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 Show InChI InChI=1S/C21H22F2N6O6S/c1-2-34-14-6-11(22)5-13(23)12(14)4-3-10-8-29(20-16(10)19(24)26-9-27-20)21-18(31)17(30)15(35-21)7-28-36(25,32)33/h5-6,8-9,15,17-18,21,28,30-31H,2,7H2,1H3,(H2,24,26,27)(H2,25,32,33)/t15-,17-,18-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321039 (4-Amino-5-[2-[2,6-difluoro-4-(4-hydroxy-1-piperidy...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCC(O)CC3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C25H29F2N7O5S/c26-18-8-15(33-5-3-16(35)4-6-33)9-19(27)17(18)2-1-13-11-34(25-21(13)24(28)30-12-31-25)20-7-14(22(36)23(20)37)10-32-40(29,38)39/h8-9,11-12,14,16,20,22-23,32,35-37H,3-7,10H2,(H2,28,30,31)(H2,29,38,39)/t14-,20-,22-,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320982 (4-Amino-5-[2-[2,6-difluoro-4-(4-oxo-1-piperidyl)ph...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCC(=O)CC3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H25F2N7O6S/c25-16-7-13(32-5-3-14(34)4-6-32)8-17(26)15(16)2-1-12-10-33(23-19(12)22(27)29-11-30-23)24-21(36)20(35)18(39-24)9-31-40(28,37)38/h7-8,10-11,18,20-21,24,31,35-36H,3-6,9H2,(H2,27,29,30)(H2,28,37,38)/t18-,20-,21-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321037 (4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamo...) Show SMILES Nc1ncnc2n(cc(C#Cc3cccc4CCS(=O)(=O)c34)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C22H24N6O6S2/c23-21-17-14(5-4-12-2-1-3-13-6-7-35(31,32)20(12)13)10-28(22(17)26-11-25-21)16-8-15(18(29)19(16)30)9-27-36(24,33)34/h1-3,10-11,15-16,18-19,27,29-30H,6-9H2,(H2,23,25,26)(H2,24,33,34)/t15-,16-,18-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321040 (4-Amino-5-[2-[2,6-difluoro-4-[(3R)-3-hydroxypyrrol...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CC[C@@H](O)C3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H27F2N7O5S/c25-17-6-14(32-4-3-15(34)10-32)7-18(26)16(17)2-1-12-9-33(24-20(12)23(27)29-11-30-24)19-5-13(21(35)22(19)36)8-31-39(28,37)38/h6-7,9,11,13,15,19,21-22,31,34-36H,3-5,8,10H2,(H2,27,29,30)(H2,28,37,38)/t13-,15-,19-,21-,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321006 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES CCS(=O)(=O)c1cc(cc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12)N1CC[C@@H](O)C1 Show InChI InChI=1S/C25H30FN7O8S2/c1-2-42(37,38)19-8-14(32-6-5-15(34)11-32)7-17(26)16(19)4-3-13-10-33(24-20(13)23(27)29-12-30-24)25-22(36)21(35)18(41-25)9-31-43(28,39)40/h7-8,10,12,15,18,21-22,25,31,34-36H,2,5-6,9,11H2,1H3,(H2,27,29,30)(H2,28,39,40)/t15-,18-,21-,22-,25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320990 (4-Amino-5-[2-(2,6-difluoro-4-hydroxy-phenyl)ethyny...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(O)cc3F)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C19H18F2N6O6S/c20-11-3-9(28)4-12(21)10(11)2-1-8-6-27(18-14(8)17(22)24-7-25-18)19-16(30)15(29)13(33-19)5-26-34(23,31)32/h3-4,6-7,13,15-16,19,26,28-30H,5H2,(H2,22,24,25)(H2,23,31,32)/t13-,15-,16-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320970 (4-Amino-5-[2-[2,6-difluoro-4-(methylamino)phenyl]e...) Show SMILES CNc1cc(F)c(C#Cc2cn([C@@H]3O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)c(F)c1 Show InChI InChI=1S/C20H21F2N7O5S/c1-25-10-4-12(21)11(13(22)5-10)3-2-9-7-29(19-15(9)18(23)26-8-27-19)20-17(31)16(30)14(34-20)6-28-35(24,32)33/h4-5,7-8,14,16-17,20,25,28,30-31H,6H2,1H3,(H2,23,26,27)(H2,24,32,33)/t14-,16-,17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321009 (4-Amino-5-[2-(5-benzyloxypyrimidin-2-yl)ethynyl]-7...) Show SMILES Nc1ncnc2n(cc(C#Cc3ncc(OCc4ccccc4)cn3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H24N8O6S/c25-22-19-15(6-7-18-27-8-16(9-28-18)37-12-14-4-2-1-3-5-14)11-32(23(19)30-13-29-22)24-21(34)20(33)17(38-24)10-31-39(26,35)36/h1-5,8-9,11,13,17,20-21,24,31,33-34H,10,12H2,(H2,25,29,30)(H2,26,35,36)/t17-,20-,21-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321036 (4-Amino-5-[2-[2,6-difluoro-4-[(3S)-3-fluoropyrroli...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CC[C@H](F)C3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H26F3N7O4S/c25-14-3-4-33(10-14)15-6-17(26)16(18(27)7-15)2-1-12-9-34(24-20(12)23(28)30-11-31-24)19-5-13(21(35)22(19)36)8-32-39(29,37)38/h6-7,9,11,13-14,19,21-22,32,35-36H,3-5,8,10H2,(H2,28,30,31)(H2,29,37,38)/t13-,14+,19-,21-,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320992 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES CC(C)Oc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 Show InChI InChI=1S/C22H25FN6O6S/c1-11(2)34-15-5-3-4-14(23)13(15)7-6-12-9-29(21-17(12)20(24)26-10-27-21)22-19(31)18(30)16(35-22)8-28-36(25,32)33/h3-5,9-11,16,18-19,22,28,30-31H,8H2,1-2H3,(H2,24,26,27)(H2,25,32,33)/t16-,18-,19-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321016 (4-Amino-5-[2-[2-(cyclopropylmethoxy)-6-fluoro-phen...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cccc3OCC3CC3)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C23H25FN6O6S/c24-15-2-1-3-16(35-10-12-4-5-12)14(15)7-6-13-9-30(22-18(13)21(25)27-11-28-22)23-20(32)19(31)17(36-23)8-29-37(26,33)34/h1-3,9,11-12,17,19-20,23,29,31-32H,4-5,8,10H2,(H2,25,27,28)(H2,26,33,34)/t17-,19-,20-,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320962 (8-[2-[4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(s...) Show SMILES Nc1ncnc2n(cc(C#Cc3cccc4cccnc34)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C22H21N7O5S/c23-20-16-14(7-6-13-4-1-3-12-5-2-8-25-17(12)13)10-29(21(16)27-11-26-20)22-19(31)18(30)15(34-22)9-28-35(24,32)33/h1-5,8,10-11,15,18-19,22,28,30-31H,9H2,(H2,23,26,27)(H2,24,32,33)/t15-,18-,19-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321019 (2-[2-[4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(s...) Show SMILES Nc1ncnc2n(cc(C#Cc3ccccc3S(N)(=O)=O)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O |$_AV:;4;3;2;1;7a;7;6;5;2;1;2;3;4;5;6;1;;;;;4a;2;1;5;1;;;;;;4;;3;$| Show InChI InChI=1S/C19H21N7O7S2/c20-17-14-11(6-5-10-3-1-2-4-13(10)34(21,29)30)8-26(18(14)24-9-23-17)19-16(28)15(27)12(33-19)7-25-35(22,31)32/h1-4,8-9,12,15-16,19,25,27-28H,7H2,(H2,20,23,24)(H2,21,29,30)(H2,22,31,32)/t12-,15-,16-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321012 (4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...) Show SMILES COc1cnc(OC)c(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 Show InChI InChI=1S/C20H22FN7O7S/c1-33-11-5-24-19(34-2)14(21)10(11)4-3-9-7-28(18-13(9)17(22)25-8-26-18)20-16(30)15(29)12(35-20)6-27-36(23,31)32/h5,7-8,12,15-16,20,27,29-30H,6H2,1-2H3,(H2,22,25,26)(H2,23,31,32)/t12-,15-,16-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM320993 (4-Amino-5-[2-(4-cyano-2,6-difluoro-phenyl)ethynyl]...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)C#N)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C20H17F2N7O5S/c21-12-3-9(5-23)4-13(22)11(12)2-1-10-7-29(19-15(10)18(24)26-8-27-19)20-17(31)16(30)14(34-20)6-28-35(25,32)33/h3-4,7-8,14,16-17,20,28,30-31H,6H2,(H2,24,26,27)(H2,25,32,33)/t14-,16-,17-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321041 (4-Amino-5-[2-[2,6-difluoro-4-[(3S)-3-hydroxypyrrol...) Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CC[C@H](O)C3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C24H27F2N7O5S/c25-17-6-14(32-4-3-15(34)10-32)7-18(26)16(17)2-1-12-9-33(24-20(12)23(27)29-11-30-24)19-5-13(21(35)22(19)36)8-31-39(28,37)38/h6-7,9,11,13,15,19,21-22,31,34-36H,3-5,8,10H2,(H2,27,29,30)(H2,28,37,38)/t13-,15+,19-,21-,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair
NEDD8-conjugating enzyme UBE2F (Homo sapiens (Human))	BDBM321054 (US10174040, Example 138 | US9963456, Example 138 |...) Show SMILES Cc1ccc(Cn2cc(cn2)-c2cn([C@H]3C[C@H](O)[C@@H](COS(N)(=O)=O)C3)c3ncnc(N)c23)cc1C |$_AV:;4;5;6;1;;1;5;4;3;2;5;6;7;4;3;2;;1;1;;;;;;5;7a;1;2;3;4;;4a;2;3;$| Show InChI InChI=1S/C24H29N7O4S/c1-14-3-4-16(5-15(14)2)9-30-10-18(8-29-30)20-11-31(24-22(20)23(25)27-13-28-24)19-6-17(21(32)7-19)12-35-36(26,33)34/h3-5,8,10-11,13,17,19,21,32H,6-7,9,12H2,1-2H3,(H2,25,27,28)(H2,26,33,34)/t17-,19-,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...				US Patent US10174040 (2019) BindingDB Entry DOI: 10.7270/Q25T3NK2
					More data for this Ligand-Target Pair

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