Compile Data Set for Download or QSAR

Found 106 hits with Last Name = 'klaasse' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM89440 (4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...) Show SMILES CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C21H37ClN/c1-4-7-8-9-11-18-23(5-2,6-3)19-12-10-13-20-14-16-21(22)17-15-20/h14-17H,4-13,18-19H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12 |r| Show InChI InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description In vitro binding affinity towards human adenosine A1 receptor by [3H]DPCPX displacement.				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50095760 (CHEMBL3093959) Show SMILES CCCCCCCN(CC)CCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H32ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h12-15H,3-11,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494716 (CHEMBL3093986) Show SMILES CCCCCCCN(CC)C\C=C\Cc1ccc(Cl)cc1 Show InChI InChI=1S/C19H30ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h8,10,12-15H,3-7,9,11,16-17H2,1-2H3/b10-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [125 I]-IABMECA binding to human adenosine A3 receptor				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description In vitro binding affinity towards human adenosine A1 receptor by [3H]DPCPX displacement.				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50370303 (CHEMBL605486) Show SMILES Nc1nc(N=NNC(=O)Nc2cccc(Cl)c2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O |r,w:5.5| Show InChI InChI=1S/C17H18ClN9O5/c18-7-2-1-3-8(4-7)21-17(31)25-26-24-16-22-13(19)10-14(23-16)27(6-20-10)15-12(30)11(29)9(5-28)32-15/h1-4,6,9,11-12,15,28-30H,5H2,(H4,19,21,22,23,24,25,31)/t9-,11-,12-,15?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description In vitro binding affinity towards human adenosine A1 receptor by [3H]DPCPX displacement.				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50370303 (CHEMBL605486) Show SMILES Nc1nc(N=NNC(=O)Nc2cccc(Cl)c2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O |r,w:5.5| Show InChI InChI=1S/C17H18ClN9O5/c18-7-2-1-3-8(4-7)21-17(31)25-26-24-16-22-13(19)10-14(23-16)27(6-20-10)15-12(30)11(29)9(5-28)32-15/h1-4,6,9,11-12,15,28-30H,5H2,(H4,19,21,22,23,24,25,31)/t9-,11-,12-,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Binding affinity for human Adenosine A3 receptor using [125 I]-IABMECA				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM21220 ((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...) Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Tested for binding affinity towards human adenosine A2A receptor using [3H]ZM-241385 as radioligand				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494719 (CHEMBL3093976) Show SMILES CCCCCCCN(CC)CC#CCCc1ccc(Cl)cc1 Show InChI InChI=1S/C20H30ClN/c1-3-5-6-7-10-17-22(4-2)18-11-8-9-12-19-13-15-20(21)16-14-19/h13-16H,3-7,9-10,12,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494720 (CHEMBL3093969) Show SMILES CCCCCCCN(CC)CC#CCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H28ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h12-15H,3-7,9,11,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	167	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12 |r| Show InChI InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	281	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [125 I]-IABMECA binding to human adenosine A3 receptor				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494731 (CHEMBL3093982) Show SMILES CCCCCCCN(CC)CC#CCOc1ccc(Cl)cc1 Show InChI InChI=1S/C19H28ClNO/c1-3-5-6-7-8-15-21(4-2)16-9-10-17-22-19-13-11-18(20)12-14-19/h11-14H,3-8,15-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	478	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50370311 (CHEMBL603394) Show SMILES Nc1nc(NN=NC(=O)Oc2ccccc2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O |r,w:6.6| Show InChI InChI=1S/C17H18N8O6/c18-13-10-14(25(7-19-10)15-12(28)11(27)9(6-26)31-15)21-16(20-13)22-24-23-17(29)30-8-4-2-1-3-5-8/h1-5,7,9,11-12,15,26-28H,6H2,(H3,18,20,21,22,23,29)/t9-,11-,12-,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	577	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [125 I]-IABMECA binding to human adenosine A3 receptor				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12 |r| Show InChI InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	639	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Tested for binding affinity towards human adenosine A2A receptor using [3H]ZM-241385 as radioligand				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494724 (CHEMBL3093979) Show SMILES CCCCN(CC)CC#CC#Cc1ccc(Cl)cc1 Show InChI InChI=1S/C17H20ClN/c1-3-5-14-19(4-2)15-8-6-7-9-16-10-12-17(18)13-11-16/h10-13H,3-5,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)nc(Cl)nc12 |r| Show InChI InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of cAMP formation in CHO cells expressing adenosine A1 receptor				J Med Chem 46: 1492-503 (2003) Article DOI: 10.1021/jm021074j BindingDB Entry DOI: 10.7270/Q2MG7Q7H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494721 (CHEMBL3093957) Show SMILES [I-].CCCCCCC[N+](CC)(CC)C\C=C\Cc1ccc(Cl)cc1 Show InChI InChI=1S/C21H35ClN/c1-4-7-8-9-11-18-23(5-2,6-3)19-12-10-13-20-14-16-21(22)17-15-20/h10,12,14-17H,4-9,11,13,18-19H2,1-3H3/q+1/b12-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM89440 (4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...) Show SMILES CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C21H37ClN/c1-4-7-8-9-11-18-23(5-2,6-3)19-12-10-13-20-14-16-21(22)17-15-20/h14-17H,4-13,18-19H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50031720 ((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...) Show SMILES CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50095760 (CHEMBL3093959) Show SMILES CCCCCCCN(CC)CCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H32ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h12-15H,3-11,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp technique				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494720 (CHEMBL3093969) Show SMILES CCCCCCCN(CC)CC#CCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H28ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h12-15H,3-7,9,11,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp technique				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494716 (CHEMBL3093986) Show SMILES CCCCCCCN(CC)C\C=C\Cc1ccc(Cl)cc1 Show InChI InChI=1S/C19H30ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h8,10,12-15H,3-7,9,11,16-17H2,1-2H3/b10-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp technique				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427986 (CHEMBL2324254) Show SMILES CN(CCOc1ccc(C)cc1)CCc1ccc(C)cc1 Show InChI InChI=1S/C19H25NO/c1-16-4-8-18(9-5-16)12-13-20(3)14-15-21-19-10-6-17(2)7-11-19/h4-11H,12-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427984 (CHEMBL2324257) Show SMILES Clc1ccc(OCCCc2cccc(CCCOc3ccc(Cl)cc3)n2)cc1 Show InChI InChI=1S/C23H23Cl2NO2/c24-18-8-12-22(13-9-18)27-16-2-6-20-4-1-5-21(26-20)7-3-17-28-23-14-10-19(25)11-15-23/h1,4-5,8-15H,2-3,6-7,16-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427981 (CHEMBL2324260) Show SMILES Cc1ccc(Cc2cccc(COc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C22H24NO/c1-17-7-11-19(12-8-17)15-20-5-4-6-21(23(20)3)16-24-22-13-9-18(2)10-14-22/h4-14H,15-16H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427983 (CHEMBL2324258) Show SMILES Cc1ccc(Cc2cccc(COc3ccc(C)cc3)n2)cc1 Show InChI InChI=1S/C21H21NO/c1-16-6-10-18(11-7-16)14-19-4-3-5-20(22-19)15-23-21-12-8-17(2)9-13-21/h3-13H,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427982 (CHEMBL2324259) Show SMILES Cc1ccc(Cc2ccnc(COc3ccc(C)cc3)c2)cc1 Show InChI InChI=1S/C21H21NO/c1-16-3-7-18(8-4-16)13-19-11-12-22-20(14-19)15-23-21-9-5-17(2)6-10-21/h3-12,14H,13,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427960 (CHEMBL2324244) Show SMILES C[n+]1c(CCCOc2ccc(Cl)cc2)cccc1CCCOc1ccc(Cl)cc1 Show InChI InChI=1S/C24H26Cl2NO2/c1-27-21(7-3-17-28-23-13-9-19(25)10-14-23)5-2-6-22(27)8-4-18-29-24-15-11-20(26)12-16-24/h2,5-6,9-16H,3-4,7-8,17-18H2,1H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427971 (CHEMBL2325208) Show SMILES CCCCCCCCc1cccc(CCCCCCCC)[n+]1C Show InChI InChI=1S/C22H40N/c1-4-6-8-10-12-14-17-21-19-16-20-22(23(21)3)18-15-13-11-9-7-5-2/h16,19-20H,4-15,17-18H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427952 (CHEMBL2325199) Show SMILES Cc1ccc(CCCOCc2cccc(COCCCc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C28H36NO2/c1-23-11-15-25(16-12-23)7-5-19-30-21-27-9-4-10-28(29(27)3)22-31-20-6-8-26-17-13-24(2)14-18-26/h4,9-18H,5-8,19-22H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427974 (CHEMBL2325204) Show SMILES Cc1ccc(CCc2cccc(CCc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C24H28N/c1-19-7-11-21(12-8-19)15-17-23-5-4-6-24(25(23)3)18-16-22-13-9-20(2)10-14-22/h4-14H,15-18H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427951 (CHEMBL2325200) Show SMILES Cc1ccc(cc1)C#CCOCc1cccc(COCC#Cc2ccc(C)cc2)[n+]1C Show InChI InChI=1S/C28H28NO2/c1-23-11-15-25(16-12-23)7-5-19-30-21-27-9-4-10-28(29(27)3)22-31-20-6-8-26-17-13-24(2)14-18-26/h4,9-18H,19-22H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50095764 (CHEMBL3140084) Show SMILES CCCCCCC[N+](CC)(CC)CC#Cc1ccc(Cl)cc1 Show InChI InChI=1S/C14H15N3O/c1-10-4-3-5-11(2)13(10)17-14(18)16-12-6-8-15-9-7-12/h3-9H,1-2H3,(H2,15,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50095760 (CHEMBL3093959) Show SMILES CCCCCCCN(CC)CCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H32ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h12-15H,3-11,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494716 (CHEMBL3093986) Show SMILES CCCCCCCN(CC)C\C=C\Cc1ccc(Cl)cc1 Show InChI InChI=1S/C19H30ClN/c1-3-5-6-7-9-16-21(4-2)17-10-8-11-18-12-14-19(20)15-13-18/h8,10,12-15H,3-7,9,11,16-17H2,1-2H3/b10-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM89440 (4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...) Show SMILES CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C21H37ClN/c1-4-7-8-9-11-18-23(5-2,6-3)19-12-10-13-20-14-16-21(22)17-15-20/h14-17H,4-13,18-19H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp technique				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494719 (CHEMBL3093976) Show SMILES CCCCCCCN(CC)CC#CCCc1ccc(Cl)cc1 Show InChI InChI=1S/C20H30ClN/c1-3-5-6-7-10-17-22(4-2)18-11-8-9-12-19-13-15-20(21)16-14-19/h13-16H,3-7,9-10,12,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp technique				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427979 (CHEMBL2324262) Show SMILES Cc1ccc(OCc2cccc(COc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C22H24NO2/c1-17-7-11-21(12-8-17)24-15-19-5-4-6-20(23(19)3)16-25-22-13-9-18(2)10-14-22/h4-14H,15-16H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494731 (CHEMBL3093982) Show SMILES CCCCCCCN(CC)CC#CCOc1ccc(Cl)cc1 Show InChI InChI=1S/C19H28ClNO/c1-3-5-6-7-8-15-21(4-2)16-9-10-17-22-19-13-11-18(20)12-14-19/h11-14H,3-8,15-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp technique				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494733 (CHEMBL3093962) Show SMILES CCCCCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H31N/c1-2-3-4-5-9-14-20-15-12-19(13-16-20)17-18-10-7-6-8-11-18/h6-8,10-11,19H,2-5,9,12-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427959 (CHEMBL2324245) Show SMILES C[n+]1c(CCCOc2cccc(Cl)c2)cccc1CCCOc1cccc(Cl)c1 Show InChI InChI=1S/C24H26Cl2NO2/c1-27-21(11-5-15-28-23-13-2-7-19(25)17-23)9-4-10-22(27)12-6-16-29-24-14-3-8-20(26)18-24/h2-4,7-10,13-14,17-18H,5-6,11-12,15-16H2,1H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427957 (2,6-Bis(Phenoxymethyl)Pyridine | CHEMBL2324247) Show SMILES C(Oc1ccccc1)c1cccc(COc2ccccc2)n1 Show InChI InChI=1S/C19H17NO2/c1-3-10-18(11-4-1)21-14-16-8-7-9-17(20-16)15-22-19-12-5-2-6-13-19/h1-13H,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427958 (CHEMBL2324246) Show SMILES C[n+]1c(CCCOc2ccccc2Cl)cccc1CCCOc1ccccc1Cl Show InChI InChI=1S/C24H26Cl2NO2/c1-27-19(11-7-17-28-23-15-4-2-13-21(23)25)9-6-10-20(27)12-8-18-29-24-16-5-3-14-22(24)26/h2-6,9-10,13-16H,7-8,11-12,17-18H2,1H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427950 (CHEMBL2325205) Show SMILES Cc1ccc(OCCCc2cccc(CCCOc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C26H32NO2/c1-21-11-15-25(16-12-21)28-19-5-9-23-7-4-8-24(27(23)3)10-6-20-29-26-17-13-22(2)14-18-26/h4,7-8,11-18H,5-6,9-10,19-20H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427978 (CHEMBL2324263) Show SMILES Cc1ccc(COCc2cccc(COCc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C24H28NO2/c1-19-7-11-21(12-8-19)15-26-17-23-5-4-6-24(25(23)3)18-27-16-22-13-9-20(2)10-14-22/h4-14H,15-18H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494747 (CHEMBL3093961) Show SMILES CCCCCCCN(CC)CCCCCc1ccc(Cl)cc1 Show InChI InChI=1S/C20H34ClN/c1-3-5-6-7-10-17-22(4-2)18-11-8-9-12-19-13-15-20(21)16-14-19/h13-16H,3-12,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50494732 (CHEMBL3093963) Show SMILES CCCCCCCN1CCC(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C19H29NO/c1-2-3-4-5-9-14-20-15-12-18(13-16-20)19(21)17-10-7-6-8-11-17/h6-8,10-11,18H,2-5,9,12-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysis				J Med Chem 56: 9427-40 (2013) Article DOI: 10.1021/jm4010434 BindingDB Entry DOI: 10.7270/Q21C20T7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427977 (CHEMBL2324264) Show SMILES Cc1ccc(CCOCc2cccc(COCCc3ccc(C)cc3)[n+]2C)cc1 Show InChI InChI=1S/C26H32NO2/c1-21-7-11-23(12-8-21)15-17-28-19-25-5-4-6-26(27(25)3)20-29-18-16-24-13-9-22(2)10-14-24/h4-14H,15-20H2,1-3H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]astemizole from human ERG K+ channel expressed in HEK293 cells by scintillation spectrophotometric analysis				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50427953 (CHEMBL2324256) Show SMILES Cc1ccc(OCCCc2cc(N)cc(CCCOc3ccc(C)cc3)n2)cc1 Show InChI InChI=1S/C25H30N2O2/c1-19-7-11-24(12-8-19)28-15-3-5-22-17-21(26)18-23(27-22)6-4-16-29-25-13-9-20(2)10-14-25/h7-14,17-18H,3-6,15-16H2,1-2H3,(H2,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of human ERG K+ channel expressed in HEK293 cells after 15 mins by patch clamp assay				J Med Chem 56: 2828-40 (2013) Article DOI: 10.1021/jm301564f BindingDB Entry DOI: 10.7270/Q22V2HG3
					More data for this Ligand-Target Pair

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