Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393794 (CHEMBL2159537) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393798 (CHEMBL2159525) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393793 (CHEMBL2159527) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393797 (CHEMBL2159535) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 4.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393799 (CHEMBL2159526) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 5.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393800 (CHEMBL2159536) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 6.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393796 (CHEMBL2159513) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 8.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine--tRNA ligase, cytoplasmic (Homo sapiens (Human)) | BDBM50393795 (CHEMBL2159512) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of human mitochondrial MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-... | J Med Chem 55: 6342-51 (2012) Article DOI: 10.1021/jm300303e BindingDB Entry DOI: 10.7270/Q2SJ1MQH | |||||||||||
More data for this Ligand-Target Pair |