Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM50097393 (CHEMBL3586447) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, 10410 Science Center Drive, San Diego, California 92121, United States. Curated by ChEMBL | Assay Description Inhibition of human recombinant Btk | J Med Chem 58: 5437-44 (2015) Article DOI: 10.1021/acs.jmedchem.5b00734 BindingDB Entry DOI: 10.7270/Q25B047D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167916 (CHEMBL3798615) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167915 (CHEMBL3798727) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210977 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167926 (CHEMBL3798871) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167922 (CHEMBL3797286) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167929 (CHEMBL3798702) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167959 (CHEMBL3799242) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210971 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167274 (CHEMBL3797399) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167275 (CHEMBL3798249) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167960 (CHEMBL3799512) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210979 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167961 (CHEMBL3800596) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210992 ((R,E)-3-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167917 (CHEMBL3797663) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167280 (CHEMBL3797259) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167279 (CHEMBL3799090) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210992 ((R,E)-3-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cells | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 (Homo sapiens (Human)) | BDBM50097393 (CHEMBL3586447) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, 10410 Science Center Drive, San Diego, California 92121, United States. Curated by ChEMBL | Assay Description Inhibition of human recombinant ALK2 by LanthaScreen Binding assay | J Med Chem 58: 5437-44 (2015) Article DOI: 10.1021/acs.jmedchem.5b00734 BindingDB Entry DOI: 10.7270/Q25B047D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210977 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxis | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167276 (CHEMBL3798844) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167278 (CHEMBL3800236) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167919 (CHEMBL3799449) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210976 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167921 (CHEMBL3800534) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167920 (CHEMBL3800546) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167918 (CHEMBL3799467) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167923 (CHEMBL3797707) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210977 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cells | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167285 (CHEMBL3797780) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167281 (CHEMBL3799796) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167914 (CHEMBL3798034) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activated CDC42 kinase 1 (Homo sapiens (Human)) | BDBM50097393 (CHEMBL3586447) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, 10410 Science Center Drive, San Diego, California 92121, United States. Curated by ChEMBL | Assay Description Inhibition of human recombinant TNK2 by LanthaScreen Binding assay | J Med Chem 58: 5437-44 (2015) Article DOI: 10.1021/acs.jmedchem.5b00734 BindingDB Entry DOI: 10.7270/Q25B047D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167927 (CHEMBL3800090) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210972 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cells | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210972 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxis | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
LIM domain kinase 1 (Homo sapiens (Human)) | BDBM50097393 (CHEMBL3586447) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, 10410 Science Center Drive, San Diego, California 92121, United States. Curated by ChEMBL | Assay Description Inhibition of human recombinant LIMK1 by LanthaScreen Binding assay | J Med Chem 58: 5437-44 (2015) Article DOI: 10.1021/acs.jmedchem.5b00734 BindingDB Entry DOI: 10.7270/Q25B047D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210972 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167925 (CHEMBL3798047) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210982 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167277 (CHEMBL3797386) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo... | Bioorg Med Chem Lett 26: 2779-2783 (2016) Article DOI: 10.1016/j.bmcl.2016.04.072 BindingDB Entry DOI: 10.7270/Q29P33K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210983 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210973 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxis | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein 2 (Homo sapiens (Human)) | BDBM50167924 (CHEMBL3798381) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California Curated by ChEMBL | Assay Description Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo... | Bioorg Med Chem Lett 26: 2774-2778 (2016) Article DOI: 10.1016/j.bmcl.2016.04.073 BindingDB Entry DOI: 10.7270/Q2DF6T4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage inflammatory protein-1 alpha receptor (Rattus norvegicus) | BDBM50210979 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Binding affinity at rat CCR1 | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210970 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxis | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210970 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPR | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50208999 ((R)-1-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxis | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50210979 ((R)-3-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories, Inc. Curated by ChEMBL | Assay Description Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cells | Bioorg Med Chem Lett 17: 3367-72 (2007) Article DOI: 10.1016/j.bmcl.2007.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1KK9 | |||||||||||
More data for this Ligand-Target Pair |
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