Compile Data Set for Download or QSAR

Found 391 hits with Last Name = 'kozarich' and Initial = 'jw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171552 ((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidine...) Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 4				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50050517 (Boronic acid derivative | CHEMBL305170 | N-alkyl G...) Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H]1B(O)O Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP4 using Gly-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171546 ((S)-2,4-Diamino-N-((R)-1-boron-dihydroxide-pentyl)...) Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CCN)B(O)O Show InChI InChI=1S/C9H22BN3O3/c1-2-3-4-8(10(15)16)13-9(14)7(12)5-6-11/h7-8,15-16H,2-6,11-12H2,1H3,(H,13,14)/t7-,8+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 7				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362508 (CHEMBL1940976) Show SMILES C[C@H]1COc2c(NCCNc3ccccn3)c(F)c(N)c3c2n1cc(C#N)c3=O |r| Show InChI InChI=1S/C20H19FN6O2/c1-11-10-29-20-17(26-7-6-25-13-4-2-3-5-24-13)15(21)16(23)14-18(20)27(11)9-12(8-22)19(14)28/h2-5,9,11,26H,6-7,10,23H2,1H3,(H,24,25)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362522 (CHEMBL1940990) Show SMILES C[C@H]1COc2c(NCCCc3ccccn3)c(F)c(N)c3c2n1cc(C#N)c3=O |r| Show InChI InChI=1S/C21H20FN5O2/c1-12-11-29-21-18(26-8-4-6-14-5-2-3-7-25-14)16(22)17(24)15-19(21)27(12)10-13(9-23)20(15)28/h2-3,5,7,10,12,26H,4,6,8,11,24H2,1H3/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171555 ((S)-2,4-Diamino-1-(2-boron-dihydroxide-pyrrolidin-...) Show SMILES NCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C8H18BN3O3/c10-4-3-6(11)8(13)12-5-1-2-7(12)9(14)15/h6-7,14-15H,1-5,10-11H2/t6-,7+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 7				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171653 (CHEMBL196120 | N-alkyl Gly-boro-Pro derivative) Show SMILES C[C@@H](N)C(=O)N1CCC[C@H]1B(O)O Show InChI InChI=1S/C7H15BN2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6,12-13H,2-4,9H2,1H3/t5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP4 using Gly-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362513 (CHEMBL1940981) Show SMILES C[C@H]1COc2c(NCCCn3cccn3)c(F)c(N)c3c2n1cc(C#N)c3=O |r| Show InChI InChI=1S/C19H19FN6O2/c1-11-10-28-19-16(23-4-2-6-25-7-3-5-24-25)14(20)15(22)13-17(19)26(11)9-12(8-21)18(13)27/h3,5,7,9,11,23H,2,4,6,10,22H2,1H3/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171556 ((R)-1-((S)-2-amino-3-methylbutanamido)ethylboronic...) Show SMILES CC(C)[C@H](N)C(=O)N[C@@H](C)B(O)O |r| Show InChI InChI=1S/C7H17BN2O3/c1-4(2)6(9)7(11)10-5(3)8(12)13/h4-6,12-13H,9H2,1-3H3,(H,10,11)/t5-,6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 4				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362518 (CHEMBL1940986) Show SMILES C[C@H]1COc2c(NCCCn3ccnc3)c(F)c(N)c3c2n1cc(C#N)c3=O |r| Show InChI InChI=1S/C19H19FN6O2/c1-11-9-28-19-16(24-3-2-5-25-6-4-23-10-25)14(20)15(22)13-17(19)26(11)8-12(7-21)18(13)27/h4,6,8,10-11,24H,2-3,5,9,22H2,1H3/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171648 (CHEMBL372180 | N-alkyl Gly-boro-Pro derivative) Show SMILES CCCCCC12CCC(CC1)(CC2)NCC(=O)N1CCC[C@H]1B(O)O Show InChI InChI=1S/C19H35BN2O3/c1-2-3-4-7-18-8-11-19(12-9-18,13-10-18)21-15-17(23)22-14-5-6-16(22)20(24)25/h16,21,24-25H,2-15H2,1H3/t16-,18?,19?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362511 (CHEMBL1940979) Show SMILES C[C@H]1COc2c(NCCCc3ccccc3)c(F)c(N)c3c2n1cc(C#N)c3=O |r| Show InChI InChI=1S/C22H21FN4O2/c1-13-12-29-22-19(26-9-5-8-14-6-3-2-4-7-14)17(23)18(25)16-20(22)27(13)11-15(10-24)21(16)28/h2-4,6-7,11,13,26H,5,8-9,12,25H2,1H3/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171649 (CHEMBL196933 | N-alkyl Gly-boro-Pro derivative) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1 Show InChI InChI=1S/C13H25BN2O3/c17-13(16-9-5-8-12(16)14(18)19)10-15-11-6-3-1-2-4-7-11/h11-12,15,18-19H,1-10H2/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171548 ((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidin-...) Show SMILES CCCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C10H21BN2O3/c1-2-3-5-8(12)10(14)13-7-4-6-9(13)11(15)16/h8-9,15-16H,2-7,12H2,1H3/t8-,9+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 7				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50171552 ((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidine...) Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 min				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171645 (2-Cyclodecylamino-1-pyrrolidin-1-yl--2-borandihydr...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCCCCC1 Show InChI InChI=1S/C16H31BN2O3/c20-16(19-12-8-11-15(19)17(21)22)13-18-14-9-6-4-2-1-3-5-7-10-14/h14-15,18,21-22H,1-13H2/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362521 (CHEMBL1940989) Show SMILES C[C@H]1COc2c(NCCCc3ccccn3)c(F)c(N)c3c2n1cc(-c1nnn[nH]1)c3=O |r| Show InChI InChI=1S/C21H21FN8O2/c1-11-10-32-20-17(25-8-4-6-12-5-2-3-7-24-12)15(22)16(23)14-18(20)30(11)9-13(19(14)31)21-26-28-29-27-21/h2-3,5,7,9,11,25H,4,6,8,10,23H2,1H3,(H,26,27,28,29)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429098 (CHEMBL2335784) Show SMILES Cc1c(F)cccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-12(19)6-4-7-13(10)21-18(24)15-9-16(23)11-5-3-8-14(17(11)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171558 (2,6-Diamino-hexanoic acid ((R)-1-boron-dihydroxide...) Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CCCCN)B(O)O Show InChI InChI=1S/C11H26BN3O3/c1-2-3-7-10(12(17)18)15-11(16)9(14)6-4-5-8-13/h9-10,17-18H,2-8,13-14H2,1H3,(H,15,16)/t9-,10+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 7				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429101 (CHEMBL2335780) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-13-4-2-3-10-15(23)8-14(20-16(10)13)17(24)21-12-6-5-9(18)7-11(12)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171650 (2-Cyclooctonylamino-1-pyrrolidin-1-yl--2-borandihy...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCCC1 Show InChI InChI=1S/C14H27BN2O3/c18-14(17-10-6-9-13(17)15(19)20)11-16-12-7-4-2-1-3-5-8-12/h12-13,16,19-20H,1-11H2/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171656 (2-Cyclohexylamino-1-pyrrolidin-1-yl--2-borandihydr...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCC1 Show InChI InChI=1S/C12H23BN2O3/c16-12(9-14-10-5-2-1-3-6-10)15-8-4-7-11(15)13(17)18/h10-11,14,17-18H,1-9H2/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171548 ((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidin-...) Show SMILES CCCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C10H21BN2O3/c1-2-3-5-8(12)10(14)13-7-4-6-9(13)11(15)16/h8-9,15-16H,2-7,12H2,1H3/t8-,9+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 4				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50171647 (CHEMBL373269 | N-alkyl Gly-boro-Pro derivative) Show SMILES OB(O)[C@H]1CCCN1C(=O)CNC12CC3CC(CC(C3)C1)C2 |TLB:15:16:20:14.13.19,THB:17:18:13:16.21.15,17:16:13:18.20.19,15:14:20:16.21.17| Show InChI InChI=1S/C16H27BN2O3/c20-15(19-3-1-2-14(19)17(21)22)10-18-16-7-11-4-12(8-16)6-13(5-11)9-16/h11-14,18,21-22H,1-10H2/t11?,12?,13?,14-,16?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human FAP using Lys-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50171548 ((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidin-...) Show SMILES CCCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C10H21BN2O3/c1-2-3-5-8(12)10(14)13-7-4-6-9(13)11(15)16/h8-9,15-16H,2-7,12H2,1H3/t8-,9+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 min				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171553 (2,5-Diamino-pentanoic acid ((R)-1-boron-dihydroxid...) Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CCCN)B(O)O Show InChI InChI=1S/C10H24BN3O3/c1-2-3-6-9(11(16)17)14-10(15)8(13)5-4-7-12/h8-9,16-17H,2-7,12-13H2,1H3,(H,14,15)/t8-,9+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 7				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171653 (CHEMBL196120 | N-alkyl Gly-boro-Pro derivative) Show SMILES C[C@@H](N)C(=O)N1CCC[C@H]1B(O)O Show InChI InChI=1S/C7H15BN2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6,12-13H,2-4,9H2,1H3/t5-,6+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50171555 ((S)-2,4-Diamino-1-(2-boron-dihydroxide-pyrrolidin-...) Show SMILES NCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C8H18BN3O3/c10-4-3-6(11)8(13)12-5-1-2-7(12)9(14)15/h6-7,14-15H,1-5,10-11H2/t6-,7+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 min				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171649 (CHEMBL196933 | N-alkyl Gly-boro-Pro derivative) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1 Show InChI InChI=1S/C13H25BN2O3/c17-13(16-9-5-8-12(16)14(18)19)10-15-11-6-3-1-2-4-7-11/h11-12,15,18-19H,1-10H2/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP4 using Gly-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171657 (2-(Bicyclo[3.2.1]oct-6-ylamino)-1-((S)-2-dihydroxy...) Show SMILES OC(O)[C@@H]1CCCN1C(=O)CNC1CC2CC1CCC2 |TLB:11:12:15:17.18.19| Show InChI InChI=1S/C15H26N2O3/c18-14(17-6-2-5-13(17)15(19)20)9-16-12-8-10-3-1-4-11(12)7-10/h10-13,15-16,19-20H,1-9H2/t10?,11?,12?,13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171647 (CHEMBL373269 | N-alkyl Gly-boro-Pro derivative) Show SMILES OB(O)[C@H]1CCCN1C(=O)CNC12CC3CC(CC(C3)C1)C2 |TLB:15:16:20:14.13.19,THB:17:18:13:16.21.15,17:16:13:18.20.19,15:14:20:16.21.17| Show InChI InChI=1S/C16H27BN2O3/c20-15(19-3-1-2-14(19)17(21)22)10-18-16-7-11-4-12(8-16)6-13(5-11)9-16/h11-14,18,21-22H,1-10H2/t11?,12?,13?,14-,16?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP4 using Gly-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50296807 (5-ethyl-2-(2-(4-methylpiperazin-1-yl)pyridin-3-yl)...) Show SMILES CCc1cccc2nc(oc(=O)c12)-c1cccnc1N1CCN(C)CC1 Show InChI InChI=1S/C20H22N4O2/c1-3-14-6-4-8-16-17(14)20(25)26-19(22-16)15-7-5-9-21-18(15)24-12-10-23(2)11-13-24/h4-9H,3,10-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc Curated by ChEMBL					Assay Description Inhibition of human sputum neutrophil elastase by fluorescence based assay				Bioorg Med Chem Lett 19: 4743-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.053 BindingDB Entry DOI: 10.7270/Q2M32VT3
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171559 ((S)-2,3-Diamino-N-((R)-1-boron-dihydroxide-pentyl)...) Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CN)B(O)O Show InChI InChI=1S/C8H20BN3O3/c1-2-3-4-7(9(14)15)12-8(13)6(11)5-10/h6-7,14-15H,2-5,10-11H2,1H3,(H,12,13)/t6-,7+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidylpeptidase 7				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50296805 (5-ethyl-2-(2-(4-(1-methylpiperidin-4-yl)piperazin-...) Show SMILES CCc1cccc2nc(oc(=O)c12)-c1cccnc1N1CCN(CC1)C1CCN(C)CC1 Show InChI InChI=1S/C25H31N5O2/c1-3-18-6-4-8-21-22(18)25(31)32-24(27-21)20-7-5-11-26-23(20)30-16-14-29(15-17-30)19-9-12-28(2)13-10-19/h4-8,11,19H,3,9-10,12-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc Curated by ChEMBL					Assay Description Inhibition of human sputum neutrophil elastase by fluorescence based assay				Bioorg Med Chem Lett 19: 4743-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.053 BindingDB Entry DOI: 10.7270/Q2M32VT3
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50296806 (1-(3-(5-ethyl-4-oxo-4H-benzo[d][1,3]oxazin-2-yl)py...) Show SMILES CCc1cccc2nc(oc(=O)c12)-c1cccnc1N1CCC(CC1)C(O)=O Show InChI InChI=1S/C21H21N3O4/c1-2-13-5-3-7-16-17(13)21(27)28-19(23-16)15-6-4-10-22-18(15)24-11-8-14(9-12-24)20(25)26/h3-7,10,14H,2,8-9,11-12H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc Curated by ChEMBL					Assay Description Inhibition of human sputum neutrophil elastase by fluorescence based assay				Bioorg Med Chem Lett 19: 4743-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.053 BindingDB Entry DOI: 10.7270/Q2M32VT3
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429098 (CHEMBL2335784) Show SMILES Cc1c(F)cccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-12(19)6-4-7-13(10)21-18(24)15-9-16(23)11-5-3-8-14(17(11)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50362519 (CHEMBL1940987) Show SMILES C[C@H]1COc2c(NCCCc3ccccn3)c(F)c(N)c3c2n1cc(C(O)=O)c3=O |r| Show InChI InChI=1S/C21H21FN4O4/c1-11-10-30-20-17(25-8-4-6-12-5-2-3-7-24-12)15(22)16(23)14-18(20)26(11)9-13(19(14)27)21(28)29/h2-3,5,7,9,11,25H,4,6,8,10,23H2,1H3,(H,28,29)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Bioorg Med Chem Lett 22: 1005-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.006 BindingDB Entry DOI: 10.7270/Q2930TMF
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429101 (CHEMBL2335780) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-13-4-2-3-10-15(23)8-14(20-16(10)13)17(24)21-12-6-5-9(18)7-11(12)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50050517 (Boronic acid derivative | CHEMBL305170 | N-alkyl G...) Show SMILES CC(C)[C@@H](N)C(=O)N1CCC[C@H]1B(O)O Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human FAP using Lys-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50171552 ((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidine...) Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@@H]1B(O)O Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences Curated by ChEMBL					Assay Description Inhibitory concentration against human fibroblast activation protein alpha				Bioorg Med Chem Lett 15: 4256-60 (2005) Article DOI: 10.1016/j.bmcl.2005.06.076 BindingDB Entry DOI: 10.7270/Q2RR1XSW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50171644 (CHEMBL427012 | N-alkyl Gly-boro-Pro derivative) Show SMILES OB(O)[C@H]1CCCN1C(=O)CNC1C2CC3CC(C2)CC1C3 |wU:3.2,TLB:11:12:19:15.21.16,14:15:19:13.12.18,THB:16:17:12:15.14.21,16:15:12:17.19.18,14:13:19:15.21.16,(14.33,-8.43,;13.44,-7.16,;14.08,-5.74,;11.88,-7.31,;11.1,-8.65,;9.61,-8.32,;9.44,-6.8,;10.85,-6.16,;11.13,-4.63,;12.58,-4.12,;9.96,-3.64,;8.51,-4.15,;7.17,-4.92,;7.17,-6.47,;6.14,-7.73,;4.74,-7.17,;3.24,-7.59,;4.43,-6.32,;5.77,-6.81,;4.43,-4.83,;5.77,-4.35,;4.74,-5.58,)| Show InChI InChI=1S/C16H27BN2O3/c20-15(19-3-1-2-14(19)17(21)22)9-18-16-12-5-10-4-11(7-12)8-13(16)6-10/h10-14,16,18,21-22H,1-9H2/t10?,11?,12?,13?,14-,16?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP4 using Gly-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50354779 (CHEMBL1834330) Show SMILES Nc1c(F)c(NCCNc2ccccn2)c2OCC3(CCCC3)n3cc(C(O)=O)c(=O)c1c23 Show InChI InChI=1S/C23H24FN5O4/c24-16-17(25)15-19-21(18(16)28-10-9-27-14-5-1-4-8-26-14)33-12-23(6-2-3-7-23)29(19)11-13(20(15)30)22(31)32/h1,4-5,8,11,28H,2-3,6-7,9-10,12,25H2,(H,26,27)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assay				Bioorg Med Chem Lett 21: 5948-51 (2011) Article DOI: 10.1016/j.bmcl.2011.07.073 BindingDB Entry DOI: 10.7270/Q23T9HMH
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50354765 (CHEMBL1834315) Show SMILES Nc1c(F)c(NCCNc2ccccn2)cc2n(cc(C(O)=O)c(=O)c12)C1CC1 Show InChI InChI=1S/C20H20FN5O3/c21-17-13(23-7-8-25-15-3-1-2-6-24-15)9-14-16(18(17)22)19(27)12(20(28)29)10-26(14)11-4-5-11/h1-3,6,9-11,23H,4-5,7-8,22H2,(H,24,25)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assay				Bioorg Med Chem Lett 21: 5948-51 (2011) Article DOI: 10.1016/j.bmcl.2011.07.073 BindingDB Entry DOI: 10.7270/Q23T9HMH
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429114 (CHEMBL2335769) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1F Show InChI InChI=1S/C17H14FN3O4S/c1-26(24,25)21-13-8-4-5-10-15(22)9-14(19-16(10)13)17(23)20-12-7-3-2-6-11(12)18/h2-9,21H,1H3,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429113 (CHEMBL2335770) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1C#N Show InChI InChI=1S/C18H14N4O4S/c1-27(25,26)22-14-8-4-6-12-16(23)9-15(20-17(12)14)18(24)21-13-7-3-2-5-11(13)10-19/h2-9,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50171651 (2-Cyclopentylamino-1-pyrrolidin-1-yl--2-borandihyd...) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCC1 Show InChI InChI=1S/C11H21BN2O3/c15-11(8-13-9-4-1-2-5-9)14-7-3-6-10(14)12(16)17/h9-10,13,16-17H,1-8H2/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay				Bioorg Med Chem Lett 15: 4239-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.075 BindingDB Entry DOI: 10.7270/Q2CJ8D2F
					More data for this Ligand-Target Pair

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