Compile Data Set for Download or QSAR

Found 9 hits with Last Name = 'löwe' and Initial = 'w'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5446 (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC Show InChI InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR (unknown origin)				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5447 (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR (unknown origin)				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50247550 (4-(5-Bromoindole-3-yl)-6,7-dimethoxyquinazoline | ...) Show SMILES COc1cc2ncnc(-c3c[nH]c4ccc(Br)cc34)c2cc1OC Show InChI InChI=1S/C18H14BrN3O2/c1-23-16-6-12-15(7-17(16)24-2)21-9-22-18(12)13-8-20-14-4-3-10(19)5-11(13)14/h3-9,20H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50247551 (4-(5-Chloro-6-fluoroindole-3-yl)-6,7-dimethoxyquin...) Show SMILES COc1cc2ncnc(-c3c[nH]c4cc(F)c(Cl)cc34)c2cc1OC Show InChI InChI=1S/C18H13ClFN3O2/c1-24-16-4-10-15(6-17(16)25-2)22-8-23-18(10)11-7-21-14-5-13(20)12(19)3-9(11)14/h3-8,21H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50247161 (4-(5-Chloro-6-fluoroindole-3-yl)-7-methoxy-6-(3-mo...) Show SMILES COc1cc2ncnc(-c3c[nH]c4cc(F)c(Cl)cc34)c2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C24H24ClFN4O3/c1-31-22-12-21-16(10-23(22)33-6-2-3-30-4-7-32-8-5-30)24(29-14-28-21)17-13-27-20-11-19(26)18(25)9-15(17)20/h9-14,27H,2-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	333	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50247160 (4-(5-Chloro-6-fluoro-indole-3-yl)-6,7-di-(2-methox...) Show SMILES COCCOc1cc2ncnc(-c3c[nH]c4cc(F)c(Cl)cc34)c2cc1OCCOC Show InChI InChI=1S/C22H21ClFN3O4/c1-28-3-5-30-20-8-14-19(10-21(20)31-6-4-29-2)26-12-27-22(14)15-11-25-18-9-17(24)16(23)7-13(15)18/h7-12,25H,3-6H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	472	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50247159 (4-(6-Fluoro-5-methylindole-3-yl)-6,7-dimethoxyquin...) Show SMILES COc1cc2ncnc(-c3c[nH]c4cc(F)c(C)cc34)c2cc1OC Show InChI InChI=1S/C19H16FN3O2/c1-10-4-11-13(8-21-15(11)6-14(10)20)19-12-5-17(24-2)18(25-3)7-16(12)22-9-23-19/h4-9,21H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	533	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4363 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethio...) Show SMILES NC(=S)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human EGFR tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM4363 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethio...) Show SMILES NC(=S)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of human HER2 tyrosine kinase activity				Eur J Med Chem 43: 1478-88 (2008) Article DOI: 10.1016/j.ejmech.2007.09.018 BindingDB Entry DOI: 10.7270/Q2D50MRC
					More data for this Ligand-Target Pair