Compile Data Set for Download or QSAR

Found 27 hits with Last Name = 'lachance' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50121305 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C40H53N7O4S/c41-40(42)44-23-10-17-33(38(50)47-34(25-29-13-6-2-7-14-29)37(49)43-24-22-28-11-4-1-5-12-28)46-39(51)35(27-52)45-36(48)26-30-18-20-32(21-19-30)31-15-8-3-9-16-31/h1,3-5,8-9,11-12,15-16,18-21,29,33-35,52H,2,6-7,10,13-14,17,22-27H2,(H,43,49)(H,45,48)(H,46,51)(H,47,50)(H4,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121291 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C50H58N8O5S/c1-64-34-44(55-45(59)33-38-24-26-40(27-25-38)39-21-12-5-13-22-39)49(63)56-41(23-14-29-54-50(51)52)47(61)58-43(32-37-19-10-4-11-20-37)48(62)57-42(31-36-17-8-3-9-18-36)46(60)53-30-28-35-15-6-2-7-16-35/h2-13,15-22,24-27,41-44H,14,23,28-34H2,1H3,(H,53,60)(H,55,59)(H,56,63)(H,57,62)(H,58,61)(H4,51,52,54)/t41-,42?,43?,44?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121299 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C49H56N8O5S/c50-49(51)53-28-13-22-40(55-48(62)43(33-63)54-44(58)32-37-23-25-39(26-24-37)38-20-11-4-12-21-38)46(60)57-42(31-36-18-9-3-10-19-36)47(61)56-41(30-35-16-7-2-8-17-35)45(59)52-29-27-34-14-5-1-6-15-34/h1-12,14-21,23-26,40-43,63H,13,22,27-33H2,(H,52,59)(H,54,58)(H,55,62)(H,56,61)(H,57,60)(H4,50,51,53)/t40-,41?,42?,43?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121290 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C40H47N7O5S/c41-40(42)44-22-7-12-33(46-39(52)35(26-53)45-36(49)25-29-13-17-31(18-14-29)30-10-5-2-6-11-30)38(51)47-34(24-28-15-19-32(48)20-16-28)37(50)43-23-21-27-8-3-1-4-9-27/h1-6,8-11,13-20,33-35,48,53H,7,12,21-26H2,(H,43,50)(H,45,49)(H,46,52)(H,47,51)(H4,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121286 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C42H48N8O4S/c43-42(44)46-22-9-16-35(49-41(54)37(27-55)48-38(51)24-29-17-19-31(20-18-29)30-12-5-2-6-13-30)40(53)50-36(25-32-26-47-34-15-8-7-14-33(32)34)39(52)45-23-21-28-10-3-1-4-11-28/h1-8,10-15,17-20,26,35-37,47,55H,9,16,21-25,27H2,(H,45,52)(H,48,51)(H,49,54)(H,50,53)(H4,43,44,46)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121298 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C44H49N7O4S/c45-44(46)48-24-9-16-37(50-43(55)39(29-56)49-40(52)28-31-17-20-35(21-18-31)33-12-5-2-6-13-33)42(54)51-38(41(53)47-25-23-30-10-3-1-4-11-30)27-32-19-22-34-14-7-8-15-36(34)26-32/h1-8,10-15,17-22,26,37-39,56H,9,16,23-25,27-29H2,(H,47,53)(H,49,52)(H,50,55)(H,51,54)(H4,45,46,48)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121300 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O Show InChI InChI=1S/C41H48N8O5S/c42-37(51)33(23-27-11-4-1-5-12-27)48-39(53)34(24-28-13-6-2-7-14-28)49-38(52)32(17-10-22-45-41(43)44)47-40(54)35(26-55)46-36(50)25-29-18-20-31(21-19-29)30-15-8-3-9-16-30/h1-9,11-16,18-21,32-35,55H,10,17,22-26H2,(H2,42,51)(H,46,50)(H,47,54)(H,48,53)(H,49,52)(H4,43,44,45)/t32-,33?,34?,35?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121300 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O Show InChI InChI=1S/C41H48N8O5S/c42-37(51)33(23-27-11-4-1-5-12-27)48-39(53)34(24-28-13-6-2-7-14-28)49-38(52)32(17-10-22-45-41(43)44)47-40(54)35(26-55)46-36(50)25-29-18-20-31(21-19-29)30-15-8-3-9-16-30/h1-9,11-16,18-21,32-35,55H,10,17,22-26H2,(H2,42,51)(H,46,50)(H,47,54)(H,48,53)(H,49,52)(H4,43,44,45)/t32-,33?,34?,35?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121301 (5-Amino-2-[2-(2-biphenyl-4-yl-acetylamino)-3-methy...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCN)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C49H56N6O5S/c1-61-34-44(52-45(56)33-38-24-26-40(27-25-38)39-21-12-5-13-22-39)49(60)53-41(23-14-29-50)47(58)55-43(32-37-19-10-4-11-20-37)48(59)54-42(31-36-17-8-3-9-18-36)46(57)51-30-28-35-15-6-2-7-16-35/h2-13,15-22,24-27,41-44H,14,23,28-34,50H2,1H3,(H,51,57)(H,52,56)(H,53,60)(H,54,59)(H,55,58)/t41-,42?,43?,44?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121292 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C51H60N8O5S/c1-65-35-45(56-46(60)34-39-26-28-41(29-27-39)40-23-12-5-13-24-40)50(64)57-42(25-15-31-55-51(52)53)48(62)59-44(33-38-20-10-4-11-21-38)49(63)58-43(32-37-18-8-3-9-19-37)47(61)54-30-14-22-36-16-6-2-7-17-36/h2-13,16-21,23-24,26-29,42-45H,14-15,22,25,30-35H2,1H3,(H,54,61)(H,56,60)(H,57,64)(H,58,63)(H,59,62)(H4,52,53,55)/t42-,43?,44?,45?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121288 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES CCC(NC(=O)C(CCCNC(N)=N)NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C35H45N7O4S/c1-2-28(32(44)38-21-19-24-10-5-3-6-11-24)41-33(45)29(14-9-20-39-35(36)37)42-34(46)30(23-47)40-31(43)22-25-15-17-27(18-16-25)26-12-7-4-8-13-26/h3-8,10-13,15-18,28-30,47H,2,9,14,19-23H2,1H3,(H,38,44)(H,40,43)(H,41,45)(H,42,46)(H4,36,37,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121295 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCCC(NC(=O)C(CCCNC(N)=N)NC(=O)C(CSC)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C37H49N7O4S2/c1-49-23-20-31(34(46)40-22-19-26-10-5-3-6-11-26)44-35(47)30(14-9-21-41-37(38)39)43-36(48)32(25-50-2)42-33(45)24-27-15-17-29(18-16-27)28-12-7-4-8-13-28/h3-8,10-13,15-18,30-32H,9,14,19-25H2,1-2H3,(H,40,46)(H,42,45)(H,43,48)(H,44,47)(H4,38,39,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121289 (2-{2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulf...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(C)C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C38H51N7O4S/c1-26(2)23-32(35(47)41-22-20-27-11-6-4-7-12-27)45-36(48)31(15-10-21-42-38(39)40)44-37(49)33(25-50-3)43-34(46)24-28-16-18-30(19-17-28)29-13-8-5-9-14-29/h4-9,11-14,16-19,26,31-33H,10,15,20-25H2,1-3H3,(H,41,47)(H,43,46)(H,44,49)(H,45,48)(H4,39,40,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121293 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccc(cc1)-c1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C46H51N7O4S/c47-46(48)50-27-10-17-39(52-45(57)41(31-58)51-42(54)30-34-20-24-38(25-21-34)36-15-8-3-9-16-36)44(56)53-40(43(55)49-28-26-32-11-4-1-5-12-32)29-33-18-22-37(23-19-33)35-13-6-2-7-14-35/h1-9,11-16,18-25,39-41,58H,10,17,26-31H2,(H,49,55)(H,51,54)(H,52,57)(H,53,56)(H4,47,48,50)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121287 (2-[2-(2-Biphenyl-4-yl-acetylamino)-pentanoylamino]...) Show SMILES CCCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C51H60N8O5/c1-2-16-42(56-46(60)35-39-26-28-41(29-27-39)40-23-13-6-14-24-40)48(62)57-43(25-15-31-55-51(52)53)49(63)59-45(34-38-21-11-5-12-22-38)50(64)58-44(33-37-19-9-4-10-20-37)47(61)54-32-30-36-17-7-3-8-18-36/h3-14,17-24,26-29,42-45H,2,15-16,25,30-35H2,1H3,(H,54,61)(H,56,60)(H,57,62)(H,58,64)(H,59,63)(H4,52,53,55)/t42?,43-,44?,45?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50121286 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C42H48N8O4S/c43-42(44)46-22-9-16-35(49-41(54)37(27-55)48-38(51)24-29-17-19-31(20-18-29)30-12-5-2-6-13-30)40(53)50-36(25-32-26-47-34-15-8-7-14-33(32)34)39(52)45-23-21-28-10-3-1-4-11-28/h1-8,10-15,17-20,26,35-37,47,55H,9,16,21-25,27H2,(H,45,52)(H,48,51)(H,49,54)(H,50,53)(H4,43,44,46)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Specificity of Cathepsin B inhibition by the compound				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121302 (2-(2-{2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methyls...) Show SMILES CSC[C@H](NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5S/c1-49-25-33(42-34(44)23-28-17-19-30(20-18-28)29-15-9-4-10-16-29)37(47)40-24-35(45)41-32(22-27-13-7-3-8-14-27)38(48)43-31(36(39)46)21-26-11-5-2-6-12-26/h2-20,31-33H,21-25H2,1H3,(H2,39,46)(H,40,47)(H,41,45)(H,42,44)(H,43,48)/t31-,32-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50121286 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C42H48N8O4S/c43-42(44)46-22-9-16-35(49-41(54)37(27-55)48-38(51)24-29-17-19-31(20-18-29)30-12-5-2-6-13-30)40(53)50-36(25-32-26-47-34-15-8-7-14-33(32)34)39(52)45-23-21-28-10-3-1-4-11-28/h1-8,10-15,17-20,26,35-37,47,55H,9,16,21-25,27H2,(H,45,52)(H,48,51)(H,49,54)(H,50,53)(H4,43,44,46)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Specificity of Cathepsin K inhibition by the compound				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50121290 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C40H47N7O5S/c41-40(42)44-22-7-12-33(46-39(52)35(26-53)45-36(49)25-29-13-17-31(18-14-29)30-10-5-2-6-11-30)38(51)47-34(24-28-15-19-32(48)20-16-28)37(50)43-23-21-27-8-3-1-4-9-27/h1-6,8-11,13-20,33-35,48,53H,7,12,21-26H2,(H,43,50)(H,45,49)(H,46,52)(H,47,51)(H4,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Specificity of Cathepsin K inhibition by the compound				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121297 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CCCNC(N)=N)NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C37H50N10O4S/c38-36(39)43-20-7-13-29(33(49)42-22-19-25-9-3-1-4-10-25)46-34(50)30(14-8-21-44-37(40)41)47-35(51)31(24-52)45-32(48)23-26-15-17-28(18-16-26)27-11-5-2-6-12-27/h1-6,9-12,15-18,29-31,52H,7-8,13-14,19-24H2,(H,42,49)(H,45,48)(H,46,50)(H,47,51)(H4,38,39,43)(H4,40,41,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50121291 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C50H58N8O5S/c1-64-34-44(55-45(59)33-38-24-26-40(27-25-38)39-21-12-5-13-22-39)49(63)56-41(23-14-29-54-50(51)52)47(61)58-43(32-37-19-10-4-11-20-37)48(62)57-42(31-36-17-8-3-9-18-36)46(60)53-30-28-35-15-6-2-7-16-35/h2-13,15-22,24-27,41-44H,14,23,28-34H2,1H3,(H,53,60)(H,55,59)(H,56,63)(H,57,62)(H,58,61)(H4,51,52,54)/t41-,42?,43?,44?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Specificity of Cathepsin B inhibition by the compound				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50121291 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C50H58N8O5S/c1-64-34-44(55-45(59)33-38-24-26-40(27-25-38)39-21-12-5-13-22-39)49(63)56-41(23-14-29-54-50(51)52)47(61)58-43(32-37-19-10-4-11-20-37)48(62)57-42(31-36-17-8-3-9-18-36)46(60)53-30-28-35-15-6-2-7-16-35/h2-13,15-22,24-27,41-44H,14,23,28-34H2,1H3,(H,53,60)(H,55,59)(H,56,63)(H,57,62)(H,58,61)(H4,51,52,54)/t41-,42?,43?,44?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Specificity of Cathepsin K inhibition by the compound				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121303 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C49H56N8O5S/c1-63-33-43(54-44(58)31-36-24-26-39(27-25-36)38-21-12-5-13-22-38)48(62)55-40(23-14-28-52-49(50)51)46(60)57-42(30-35-17-8-3-9-18-35)47(61)56-41(29-34-15-6-2-7-16-34)45(59)53-32-37-19-10-4-11-20-37/h2-13,15-22,24-27,40-43H,14,23,28-33H2,1H3,(H,53,59)(H,54,58)(H,55,62)(H,56,61)(H,57,60)(H4,50,51,52)/t40-,41?,42?,43?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50121290 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...) Show SMILES NC(=N)NCCCC(NC(=O)C(CS)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C40H47N7O5S/c41-40(42)44-22-7-12-33(46-39(52)35(26-53)45-36(49)25-29-13-17-31(18-14-29)30-10-5-2-6-11-30)38(51)47-34(24-28-15-19-32(48)20-16-28)37(50)43-23-21-27-8-3-1-4-9-27/h1-6,8-11,13-20,33-35,48,53H,7,12,21-26H2,(H,43,50)(H,45,49)(H,46,52)(H,47,51)(H4,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Specificity of Cathepsin B inhibition by the compound				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121294 (2-(2-Biphenyl-4-yl-acetylamino)-N*1*-{1-[1-(1-carb...) Show SMILES NC(=O)CC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O Show InChI InChI=1S/C42H49N9O6/c43-36(52)26-35(48-37(53)25-29-18-20-31(21-19-29)30-15-8-3-9-16-30)41(57)49-32(17-10-22-47-42(45)46)39(55)51-34(24-28-13-6-2-7-14-28)40(56)50-33(38(44)54)23-27-11-4-1-5-12-27/h1-9,11-16,18-21,32-35H,10,17,22-26H2,(H2,43,52)(H2,44,54)(H,48,53)(H,49,57)(H,50,56)(H,51,55)(H4,45,46,47)/t32-,33?,34?,35?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121304 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-hydroxy-propi...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)C(CO)NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O Show InChI InChI=1S/C41H48N8O6/c42-37(52)33(23-27-11-4-1-5-12-27)48-39(54)34(24-28-13-6-2-7-14-28)49-38(53)32(17-10-22-45-41(43)44)47-40(55)35(26-50)46-36(51)25-29-18-20-31(21-19-29)30-15-8-3-9-16-30/h1-9,11-16,18-21,32-35,50H,10,17,22-26H2,(H2,42,52)(H,46,51)(H,47,55)(H,48,54)(H,49,53)(H4,43,44,45)/t32-,33?,34?,35?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50121296 (2-(2-{2-[2-(2-Acetylamino-4-methylsulfanyl-butyryl...) Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(N)=O Show InChI InChI=1S/C27H40N8O8S/c1-15(36)32-18(10-11-44-2)26(42)35-20(13-22(29)38)25(41)31-14-23(39)33-19(12-16-6-4-3-5-7-16)27(43)34-17(24(30)40)8-9-21(28)37/h3-7,17-20H,8-14H2,1-2H3,(H2,28,37)(H2,29,38)(H2,30,40)(H,31,41)(H,32,36)(H,33,39)(H,34,43)(H,35,42)/t17-,18-,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair