Found 59 hits with Last Name = 'lane' and Initial = 'ac' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50227383
(CHEMBL556758)Show InChI InChI=1S/C12H14ClN3.ClH/c1-16-10-4-2-3-9(13)8(10)7-11(16)12-14-5-6-15-12;/h2-4,11H,5-7H2,1H3,(H,14,15);1H | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226939
(CHEMBL36616)Show InChI InChI=1S/C13H17N3/c1-2-16-11-6-4-3-5-10(11)9-12(16)13-14-7-8-15-13/h3-6,12H,2,7-9H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
KEGG
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MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50227384
(CHEMBL172132)Show InChI InChI=1S/C13H16ClN3/c1-2-17-11-5-3-4-10(14)9(11)8-12(17)13-15-6-7-16-13/h3-5,12H,2,6-8H2,1H3,(H,15,16) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226938
(CHEMBL38829)Show InChI InChI=1S/C12H15N3/c1-15-10-5-3-2-4-9(10)8-11(15)12-13-6-7-14-12/h2-5,11H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
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| PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
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| PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226961
(CHEMBL38788)Show InChI InChI=1S/C14H19N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h3-6,13H,2,7-10H2,1H3,(H,15,16) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50227384
(CHEMBL172132)Show InChI InChI=1S/C13H16ClN3/c1-2-17-11-5-3-4-10(14)9(11)8-12(17)13-15-6-7-16-13/h3-5,12H,2,6-8H2,1H3,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha1-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226937
(CHEMBL289153)Show InChI InChI=1S/C18H19N3/c1-2-6-14(7-3-1)13-21-16-9-5-4-8-15(16)12-17(21)18-19-10-11-20-18/h1-9,17H,10-13H2,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50226964
(CHEMBL41064)Show InChI InChI=1S/C17H17N3/c1-2-7-14(8-3-1)20-15-9-5-4-6-13(15)12-16(20)17-18-10-11-19-17/h1-9,16H,10-12H2,(H,18,19) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) | PDB
Reactome pathway
KEGG
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| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
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Similars
| Article
PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226961
(CHEMBL38788)Show InChI InChI=1S/C14H19N3/c1-2-9-17-12-6-4-3-5-11(12)10-13(17)14-15-7-8-16-14/h3-6,13H,2,7-10H2,1H3,(H,15,16) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha1-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226939
(CHEMBL36616)Show InChI InChI=1S/C13H17N3/c1-2-16-11-6-4-3-5-10(11)9-12(16)13-14-7-8-15-13/h3-6,12H,2,7-9H2,1H3,(H,14,15) | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha1-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226938
(CHEMBL38829)Show InChI InChI=1S/C12H15N3/c1-15-10-5-3-2-4-9(10)8-11(15)12-13-6-7-14-12/h2-5,11H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha-1 adrenergic receptor site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225888
(CHEMBL61325)Show InChI InChI=1S/C12H14N2O2/c1-12(11-13-6-7-14-11)8-15-9-4-2-3-5-10(9)16-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225888
(CHEMBL61325)Show InChI InChI=1S/C12H14N2O2/c1-12(11-13-6-7-14-11)8-15-9-4-2-3-5-10(9)16-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226964
(CHEMBL41064)Show InChI InChI=1S/C17H17N3/c1-2-7-14(8-3-1)20-15-9-5-4-6-13(15)12-16(20)17-18-10-11-19-17/h1-9,16H,10-12H2,(H,18,19) | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
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| PubMed
| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha1-site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50227383
(CHEMBL556758)Show InChI InChI=1S/C12H14ClN3.ClH/c1-16-10-4-2-3-9(13)8(10)7-11(16)12-14-5-6-15-12;/h2-4,11H,5-7H2,1H3,(H,14,15);1H | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha-1 adrenergic receptor site in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225887
(CHEMBL61234)Show InChI InChI=1S/C14H16N2O2/c1-10(2)14(13-15-7-8-16-13)9-17-11-5-3-4-6-12(11)18-14/h3-6H,1,7-9H2,2H3,(H,15,16) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| 16.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50226937
(CHEMBL289153)Show InChI InChI=1S/C18H19N3/c1-2-6-14(7-3-1)13-21-16-9-5-4-8-15(16)12-17(21)18-19-10-11-20-18/h1-9,17H,10-13H2,(H,19,20) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Reckitt and Colman plc
Curated by ChEMBL
| Assay Description
Inhibition of saturable binding of [3H]prazosin to alpha-1 adrenergic receptor in rat cerebral cortical membranes. |
J Med Chem 31: 944-8 (1988)
BindingDB Entry DOI: 10.7270/Q22F7QNK |
More data for this
Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
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| Article
PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
Reactome pathway
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| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
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| 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
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| 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50019848
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) | PDB
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| 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
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| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
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| 236 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
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| 256 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50225888
(CHEMBL61325)Show InChI InChI=1S/C12H14N2O2/c1-12(11-13-6-7-14-11)8-15-9-4-2-3-5-10(9)16-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
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| 449 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50225888
(CHEMBL61325)Show InChI InChI=1S/C12H14N2O2/c1-12(11-13-6-7-14-11)8-15-9-4-2-3-5-10(9)16-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
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| 449 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225888
(CHEMBL61325)Show InChI InChI=1S/C12H14N2O2/c1-12(11-13-6-7-14-11)8-15-9-4-2-3-5-10(9)16-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
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| 487 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50225887
(CHEMBL61234)Show InChI InChI=1S/C14H16N2O2/c1-10(2)14(13-15-7-8-16-13)9-17-11-5-3-4-6-12(11)18-14/h3-6H,1,7-9H2,2H3,(H,15,16) | PDB
Reactome pathway
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| 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | PDB
Reactome pathway
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| 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)Show InChI InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
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| 6.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | PDB
Reactome pathway
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| Article
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| 7.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984)
Article DOI: 10.1007/bf00506193
BindingDB Entry DOI: 10.7270/Q25B00Z5 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225887
(CHEMBL61234)Show InChI InChI=1S/C14H16N2O2/c1-10(2)14(13-15-7-8-16-13)9-17-11-5-3-4-6-12(11)18-14/h3-6H,1,7-9H2,2H3,(H,15,16) | PDB
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| 8.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50225887
(CHEMBL61234)Show InChI InChI=1S/C14H16N2O2/c1-10(2)14(13-15-7-8-16-13)9-17-11-5-3-4-6-12(11)18-14/h3-6H,1,7-9H2,2H3,(H,15,16) | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
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UniChem
Similars
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| 8.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]idazoxan from alpha-2 adrenergic receptor from rat brain cerebral cortex. |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50225888
(CHEMBL61325)Show InChI InChI=1S/C12H14N2O2/c1-12(11-13-6-7-14-11)8-15-9-4-2-3-5-10(9)16-12/h2-5H,6-8H2,1H3,(H,13,14) | PDB
Reactome pathway
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| 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50225887
(CHEMBL61234)Show InChI InChI=1S/C14H16N2O2/c1-10(2)14(13-15-7-8-16-13)9-17-11-5-3-4-6-12(11)18-14/h3-6H,1,7-9H2,2H3,(H,15,16) | PDB
Reactome pathway
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| 4.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50225887
(CHEMBL61234)Show InChI InChI=1S/C14H16N2O2/c1-10(2)14(13-15-7-8-16-13)9-17-11-5-3-4-6-12(11)18-14/h3-6H,1,7-9H2,2H3,(H,15,16) | PDB
Reactome pathway
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| 4.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from alpha-1 adrenergic receptor from rat brain cerebral cortex |
J Med Chem 29: 2000-3 (1986)
BindingDB Entry DOI: 10.7270/Q20V8G02 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50224275
(CHEMBL278717)Show SMILES [H][C@@]12Oc3c4c(CC5N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)OCC)ccc3O |THB:9:8:16:4.5.6| Show InChI InChI=1S/C22H27NO4/c1-2-26-22-8-7-16(25)20-21(22)9-10-23(12-13-3-4-13)17(22)11-14-5-6-15(24)19(27-20)18(14)21/h5-6,13,17,20,24H,2-4,7-12H2,1H3/t17?,20-,21-,22+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
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UniChem
| PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50224275
(CHEMBL278717)Show SMILES [H][C@@]12Oc3c4c(CC5N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)OCC)ccc3O |THB:9:8:16:4.5.6| Show InChI InChI=1S/C22H27NO4/c1-2-26-22-8-7-16(25)20-21(22)9-10-23(12-13-3-4-13)17(22)11-14-5-6-15(24)19(27-20)18(14)21/h5-6,13,17,20,24H,2-4,7-12H2,1H3/t17?,20-,21-,22+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM60212
((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 | PDB
MMDB
Reactome pathway
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PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50224274
(CHEMBL2304423)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)OC)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C21H25NO4/c1-25-21-7-6-15(24)19-20(21)8-9-22(11-12-2-3-12)16(21)10-13-4-5-14(23)18(26-19)17(13)20/h4-5,12,16,19,23H,2-3,6-11H2,1H3/t16-,19+,20+,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50224274
(CHEMBL2304423)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]5(CCC2=O)OC)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C21H25NO4/c1-25-21-7-6-15(24)19-20(21)8-9-22(11-12-2-3-12)16(21)10-13-4-5-14(23)18(26-19)17(13)20/h4-5,12,16,19,23H,2-3,6-11H2,1H3/t16-,19+,20+,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50224277
(CHEMBL280309)Show SMILES [H][C@@]12Oc3c4c(CC5N(CC=C)CC[C@@]14[C@]5(CCC2=O)OCC)ccc3O |THB:9:8:15:4.5.6| Show InChI InChI=1S/C21H25NO4/c1-3-10-22-11-9-20-17-13-5-6-14(23)18(17)26-19(20)15(24)7-8-21(20,25-4-2)16(22)12-13/h3,5-6,16,19,23H,1,4,7-12H2,2H3/t16?,19-,20-,21+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM60212
((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50224277
(CHEMBL280309)Show SMILES [H][C@@]12Oc3c4c(CC5N(CC=C)CC[C@@]14[C@]5(CCC2=O)OCC)ccc3O |THB:9:8:15:4.5.6| Show InChI InChI=1S/C21H25NO4/c1-3-10-22-11-9-20-17-13-5-6-14(23)18(17)26-19(20)15(24)7-8-21(20,25-4-2)16(22)12-13/h3,5-6,16,19,23H,1,4,7-12H2,2H3/t16?,19-,20-,21+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat)-RAT) | BDBM50000788
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of Na |
J Med Chem 25: 116-20 (1982)
BindingDB Entry DOI: 10.7270/Q2NZ89V4 |
More data for this
Ligand-Target Pair | |
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