Found 4060 hits with Last Name = 'lawson' and Initial = 'jd' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Son of sevenless homolog 1 [564-1049]
() | BDBM609420
(US11702418, Example 6-10)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCn2nccc2C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | <0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609446
(US11702418, Example 10-5)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCNCC(F)(F)C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | <0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609525
(US11702418, Example 11-4)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(CC1)C(=O)[C@@H]1CCOC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609526
(US11702418, Example 11-5)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(CC1)C(=O)[C@H]1CCOC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609451
(US11702418, Example 10-10)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(CC1)c1cnn(C)c1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609522
((R)-(4-(1-methyl-4-((1-(2-methyl-3-(trifluoromethy...)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(CC1)C(=O)C1COC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609523
(US11702418, Example 11-2)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(CC1)C(=O)C1CCOCC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | <0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609524
(US11702418, Example 11-3)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(CC1)C(=O)C1(CC1)C(F)(F)F)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | <0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609452
(US11702418, Example 10-11)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCn2c(C)nc(C)c2C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609413
(US11702418, Example 6-3)Show SMILES CNCc1ccccc1-c1ccc(s1)[C@@H](C)Nc1nnc(C)c2ccc(cc12)N1CCOCC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609450
(US11702418, Example 10-9)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC(C)(N)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609448
(US11702418, Example 10-7)Show SMILES CNC1CCN(CC1)c1ccc2c(C)nnc(N[C@H](C)c3cccc(c3C)C(F)(F)F)c2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609445
(US11702418, Example 10-4)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCNCC1)c1cccc(C(F)F)c1C |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609449
(US11702418, Example 10-8)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC(CC1)N(C)C)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609416
(US11702418, Example 6-6)Show SMILES CNCc1c(F)cccc1-c1ccc(s1)[C@@H](C)Nc1nnc(C)c2ccc(cc12)N1CCOCC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609411
((R)-4-methyl-N-(1-(2-methyl-3-(trifluoromethyl)phe...)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(C)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| MCE PC cid PC sid UniChem
| | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM50601067
(CHEMBL5208088 | US11702418, Example 6-4)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB
| 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Son of sevenless homolog 1 [564-1049]
() | BDBM609415
(US11702418, Example 6-5)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCOCC1)c1cc(N)cc(c1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609387
(US11702418, Example 1-28)Show SMILES C[C@@H](Nc1nncc2ccc(cc12)N1CCn2c(C1)nc(C)c2C)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609528
((R)-4-methyl-7-(4-(1-methyl-1H-pyrazol-4-yl)pipera...)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCN(CC1)c1cnn(C)c1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609468
(US11702418, Example 10-32)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1C[C@H]2CC[C@@H]1CN2C)c1cccc(c1C)C(F)(F)F |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609472
(US11702418, Example 10-36)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC2(CCNC2)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM50601075
(CHEMBL5202472 | US11702418, Example 6-9)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609473
(US11702418, Example 10-37)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC2(CCN(C)C2)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609540
(US11702418, Example 12-15)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCC(CC1)N(C)C)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609585
(US11702418, Example 12-60)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1C[C@H]2CC[C@@H]1CN2C)c1cccc(c1F)C(F)(F)F |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609394
(US11702418, Example 1-37)Show SMILES C[C@@H](Nc1nncc2ccc(cc12)N1CCn2c(C)ncc2C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609618
(US11702418, Example 12-102)Show SMILES CCN1CCN(CC1)c1cc2c(N[C@H](C)c3cccc(C(F)F)c3F)nnc(C)c2cn1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609613
(US11702418, Example 12-89)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1C[C@H]2CC[C@@H]1CN2CCO)c1cccc(C#N)c1C |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609397
(US11702418, Example 1-40)Show SMILES C[C@@H](Nc1nncc2ccc(cc12)N1CCn2cc(C)nc2C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609457
(US11702418, Example 10-19)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC2(CCCN2C)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM50601069
(CHEMBL5191446 | US11702418, Example 6-7)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(C)C(=O)C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609424
(US11702418, Example 6-13)Show SMILES CNCc1c(F)cccc1-c1ccc(s1)[C@@H](C)Nc1nnc(C)c2cnc(cc12)N1CCOCC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609558
(US11702418, Example 12-33)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCC(CC1)N1CCC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609478
(US11702418, Example 10-42)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC(C)(CC1)N(C)C)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609456
(US11702418, Example 10-18 | US11702418, Example 10...)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC2(CCCN2)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609433
(US11702418, Example 7-3)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(O[C@H]3CCNC3)cc12)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609432
(US11702418, Example 7-2)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(OC3CCNCC3)cc12)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1
(Homo sapiens (Human)) | BDBM50601067
(CHEMBL5208088 | US11702418, Example 6-4)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Son of sevenless homolog 1 [564-1049]
() | BDBM609467
(US11702418, Example 10-31)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1C[C@@H]2CC[C@H]1CN2C)c1cccc(c1C)C(F)(F)F |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609591
(US11702418, Example 12-67)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCN(C)CC1)c1cccc(c1F)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1
(Homo sapiens (Human)) | BDBM50601075
(CHEMBL5202472 | US11702418, Example 6-9)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609592
(US11702418, Example 12-68)Show SMILES CCN1CCN(CC1)c1cc2c(N[C@H](C)c3cccc(c3F)C(F)(F)F)nnc(C)c2cn1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609465
(US11702418, Example 10-29)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CC2CCC(C1)N2C)c1cccc(c1C)C(F)(F)F |r,TLB:11:14:21:17.18| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609506
(US11702418, Example 10-71)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1C[C@H]2CC[C@@H]1CN2C)c1cccc(C#N)c1C |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609431
(4-methyl-N((R)-1-(5-(2-((methylamino)methyl(...)Show SMILES CNCc1ccccc1-c1ccc(s1)[C@@H](C)Nc1nnc(C)c2ccc(O[C@H]3CCOC3)cc12 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609453
(US11702418, Example 10-12)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN2[C@H](CCC2=O)C1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609532
(US11702418, Example 12-7)Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCC(C)(O)CC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609683
(US11702418, Example 20-5)Show SMILES C[C@H](Nc1nnc(C)c2cnc(cc12)N1CC2CC(C1)O2)c1cccc(c1F)C(F)(F)C(C)(C)O |r,THB:11:14:20:17| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |
Son of sevenless homolog 1 [564-1049]
() | BDBM609466
(US11702418, Example 10-30)Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCC(CC1)N1CCC1)c1cccc(c1C)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251J6 |
More data for this Ligand-Target Pair | |