Compile Data Set for Download or QSAR

Found 183 hits with Last Name = 'lazer' and Initial = 'es'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50012780 ((3,5-Di-tert-butyl-4-hydroxy-phenyl)-thiophen-2-yl...) Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)c1cccs1 Show InChI InChI=1S/C19H24O2S/c1-18(2,3)13-10-12(16(20)15-8-7-9-22-15)11-14(17(13)21)19(4,5)6/h7-11,21H,1-6H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057000 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Br)cc2Br)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H11Br2ClN2O4S/c1-21-16(23)14(10-7-9(19)3-5-13(10)26(21,24)25)15(22)20-12-4-2-8(17)6-11(12)18/h2-7,14H,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057004 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccccc2Cl)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H12Cl2N2O4S/c1-20-16(22)14(15(21)19-12-5-3-2-4-11(12)18)10-8-9(17)6-7-13(10)25(20,23)24/h2-8,14H,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056994 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2Cl)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H11Cl3N2O4S/c1-21-16(23)14(10-6-8(17)3-5-13(10)26(21,24)25)15(22)20-12-4-2-9(18)7-11(12)19/h2-7,14H,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against cyclooxygenase of human platelets was determined				J Med Chem 30: 726-9 (1987) BindingDB Entry DOI: 10.7270/Q2Q81G93
					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (Homo sapiens)	BDBM50553598 (CHEMBL4776441) Show SMILES [H][C@@]1(O[C@@H]([C@H](NCCCC(=O)NCc2ccc(cc2)N2CCC(CC2)Oc2ccc(OC(F)(F)F)cc2)C(N)=O)[C@@]2([H])O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H](CN)[C@@H](O)[C@H]1O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DPAGT1 expressed in HEK293 (Expi293) cells incubated for 2 hrs using UDP-GlcN-Cg-FITC and alpha-dihydroundecap-renyl phosphate by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00545 BindingDB Entry DOI: 10.7270/Q2J38X6H
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50012811 (2,6-Di-tert-butyl-4-(2-thiophen-2-yl-vinyl)-phenol...) Show SMILES CC(C)(C)c1cc(\C=C\c2cccs2)cc(c1O)C(C)(C)C Show InChI InChI=1S/C20H26OS/c1-19(2,3)16-12-14(9-10-15-8-7-11-22-15)13-17(18(16)21)20(4,5)6/h7-13,21H,1-6H3/b10-9+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50057004 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccccc2Cl)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H12Cl2N2O4S/c1-20-16(22)14(15(21)19-12-5-3-2-4-11(12)18)10-8-9(17)6-7-13(10)25(20,23)24/h2-8,14H,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012772 (2,6-Dimethyl-4-(2-thiophen-3-yl-vinyl)-phenol | CH...) Show SMILES Cc1cc(\C=C\c2ccsc2)cc(C)c1O Show InChI InChI=1S/C14H14OS/c1-10-7-13(8-11(2)14(10)15)4-3-12-5-6-16-9-12/h3-9,15H,1-2H3/b4-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056997 (3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2)c2ccccc2C1=O Show InChI InChI=1S/C17H13ClN2O3/c1-20-16(22)13-5-3-2-4-12(13)14(17(20)23)15(21)19-11-8-6-10(18)7-9-11/h2-9,14H,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057001 (CHEMBL361563 | N-[6-(2,3-Difluoro-phenylsulfanyl)-...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1cccc(F)c1F Show InChI InChI=1S/C16H13F2NO3S2/c1-24(21,22)19-12-7-9-5-6-13(20)10(9)8-15(12)23-14-4-2-3-11(17)16(14)18/h2-4,7-8,19H,5-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 production				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012778 (2,6-Dimethyl-4-(2-thiophen-2-yl-vinyl)-phenol | CH...) Show SMILES Cc1cc(\C=C\c2cccs2)cc(C)c1O Show InChI InChI=1S/C14H14OS/c1-10-8-12(9-11(2)14(10)15)5-6-13-4-3-7-16-13/h3-9,15H,1-2H3/b6-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50070289 (2-Benzyl-6-chloro-3-hydroxy-4-(propane-2-sulfonyl)...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccccc2)c(=O)c2ccc(Cl)cc12 Show InChI InChI=1S/C19H18ClNO4S/c1-12(2)26(24,25)17-16-10-14(20)8-9-15(16)18(22)21(19(17)23)11-13-6-4-3-5-7-13/h3-10,12,23H,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056995 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H12Cl2N2O4S/c1-20-16(22)14(15(21)19-11-5-2-9(17)3-6-11)12-8-10(18)4-7-13(12)25(20,23)24/h2-8,14H,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012783 (2-Allyl-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol ...) Show SMILES Cc1cc(\C=C\c2cccs2)cc(CC=C)c1O Show InChI InChI=1S/C16H16OS/c1-3-5-14-11-13(10-12(2)16(14)17)7-8-15-6-4-9-18-15/h3-4,6-11,17H,1,5H2,2H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50056994 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2Cl)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H11Cl3N2O4S/c1-21-16(23)14(10-6-8(17)3-5-13(10)26(21,24)25)15(22)20-12-4-2-9(18)7-11(12)19/h2-7,14H,1H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 production				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012779 (2-Methoxy-6-propyl-4-(2-thiophen-2-yl-vinyl)-pheno...) Show SMILES CCCc1cc(\C=C\c2cccs2)cc(OC)c1O Show InChI InChI=1S/C16H18O2S/c1-3-5-13-10-12(11-15(18-2)16(13)17)7-8-14-6-4-9-19-14/h4,6-11,17H,3,5H2,1-2H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012805 (2-Methoxy-6-methyl-4-(2-thiophen-2-yl-vinyl)-pheno...) Show SMILES COc1cc(\C=C\c2cccs2)cc(C)c1O Show InChI InChI=1S/C14H14O2S/c1-10-8-11(9-13(16-2)14(10)15)5-6-12-4-3-7-17-12/h3-9,15H,1-2H3/b6-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50029616 (5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 production				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50070287 (2-(4-Fluoro-benzyl)-3-hydroxy-4-(propane-2-sulfony...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccc(F)cc2)c(=O)c2ccccc12 Show InChI InChI=1S/C19H18FNO4S/c1-12(2)26(24,25)17-15-5-3-4-6-16(15)18(22)21(19(17)23)11-13-7-9-14(20)10-8-13/h3-10,12,23H,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production; Imax=84%				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012773 (2-Ethyl-6-methoxy-4-(2-thiophen-2-yl-vinyl)-phenol...) Show SMILES CCc1cc(\C=C\c2cccs2)cc(OC)c1O Show InChI InChI=1S/C15H16O2S/c1-3-12-9-11(10-14(17-2)15(12)16)6-7-13-5-4-8-18-13/h4-10,16H,3H2,1-2H3/b7-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012768 (4-[2-(4-Methoxy-phenyl)-vinyl]-2,6-dimethyl-phenol...) Show SMILES COc1ccc(\C=C\c2cc(C)c(O)c(C)c2)cc1 Show InChI InChI=1S/C17H18O2/c1-12-10-15(11-13(2)17(12)18)5-4-14-6-8-16(19-3)9-7-14/h4-11,18H,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012798 ((E)-2,6-dimethyl-4-styrylphenol | 2,6-Dimethyl-4-s...) Show SMILES Cc1cc(\C=C\c2ccccc2)cc(C)c1O Show InChI InChI=1S/C16H16O/c1-12-10-15(11-13(2)16(12)17)9-8-14-6-4-3-5-7-14/h3-11,17H,1-2H3/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012785 (4-[2-(2-Methoxy-phenyl)-vinyl]-2,6-dimethyl-phenol...) Show SMILES COc1ccccc1\C=C\c1cc(C)c(O)c(C)c1 Show InChI InChI=1S/C17H18O2/c1-12-10-14(11-13(2)17(12)18)8-9-15-6-4-5-7-16(15)19-3/h4-11,18H,1-3H3/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50070291 (6-Chloro-2-(3,4-difluoro-benzyl)-3-hydroxy-4-(prop...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccc(F)c(F)c2)c(=O)c2ccc(Cl)cc12 Show InChI InChI=1S/C19H16ClF2NO4S/c1-10(2)28(26,27)17-14-8-12(20)4-5-13(14)18(24)23(19(17)25)9-11-3-6-15(21)16(22)7-11/h3-8,10,25H,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50008950 (3-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-dihydr...) Show SMILES CC(C)(C)c1cc(\C=C2/CCOC2=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C19H26O3/c1-18(2,3)14-10-12(9-13-7-8-22-17(13)21)11-15(16(14)20)19(4,5)6/h9-11,20H,7-8H2,1-6H3/b13-9+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50000399 (CHEMBL292136) Show SMILES Cc1cc(CCc2cccs2)cc(C)c1O Show InChI InChI=1S/C14H16OS/c1-10-8-12(9-11(2)14(10)15)5-6-13-4-3-7-16-13/h3-4,7-9,15H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012806 (4-[2-(4-Fluoro-phenyl)-vinyl]-2,6-dimethyl-phenol ...) Show SMILES Cc1cc(\C=C\c2ccc(F)cc2)cc(C)c1O Show InChI InChI=1S/C16H15FO/c1-11-9-14(10-12(2)16(11)18)4-3-13-5-7-15(17)8-6-13/h3-10,18H,1-2H3/b4-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50056997 (3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2)c2ccccc2C1=O Show InChI InChI=1S/C17H13ClN2O3/c1-20-16(22)13-5-3-2-4-12(13)14(17(20)23)15(21)19-11-8-6-10(18)7-9-11/h2-9,14H,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012793 (2,6-Dimethyl-4-(2-m-tolyl-vinyl)-phenol | CHEMBL56...) Show SMILES Cc1cccc(\C=C\c2cc(C)c(O)c(C)c2)c1 Show InChI InChI=1S/C17H18O/c1-12-5-4-6-15(9-12)7-8-16-10-13(2)17(18)14(3)11-16/h4-11,18H,1-3H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50057000 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Br)cc2Br)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H11Br2ClN2O4S/c1-21-16(23)14(10-7-9(19)3-5-13(10)26(21,24)25)15(22)20-12-4-2-8(17)6-11(12)18/h2-7,14H,1H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50070286 (4-Benzenesulfonyl-2-benzyl-3-hydroxy-2H-isoquinoli...) Show SMILES Oc1c(c2ccccc2c(=O)n1Cc1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C22H17NO4S/c24-21-19-14-8-7-13-18(19)20(28(26,27)17-11-5-2-6-12-17)22(25)23(21)15-16-9-3-1-4-10-16/h1-14,25H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056998 (4-Hydroxy-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e...) Show SMILES CN1C(C(=O)Nc2ncc(C)s2)=C(O)c2ccccc2S1(=O)=O |t:12| Show InChI InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057006 (3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccccc2)c2ccccc2C1=O Show InChI InChI=1S/C17H14N2O3/c1-19-16(21)13-10-6-5-9-12(13)14(17(19)22)15(20)18-11-7-3-2-4-8-11/h2-10,14H,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012786 (4-[2-(4-Chloro-phenyl)-vinyl]-2,6-dimethyl-phenol ...) Show SMILES Cc1cc(\C=C\c2ccc(Cl)cc2)cc(C)c1O Show InChI InChI=1S/C16H15ClO/c1-11-9-14(10-12(2)16(11)18)4-3-13-5-7-15(17)8-6-13/h3-10,18H,1-2H3/b4-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50000360 (CHEMBL55680) Show SMILES CCCOc1ccc(\C=C\c2cc(C)c(O)c(C)c2)cc1 Show InChI InChI=1S/C19H22O2/c1-4-11-21-18-9-7-16(8-10-18)5-6-17-12-14(2)19(20)15(3)13-17/h5-10,12-13,20H,4,11H2,1-3H3/b6-5+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012792 (2,6-Diisopropyl-4-(2-pyridin-3-yl-vinyl)-phenol | ...) Show SMILES CC(C)c1cc(\C=C\c2cccnc2)cc(C(C)C)c1O Show InChI InChI=1S/C19H23NO/c1-13(2)17-10-16(11-18(14(3)4)19(17)21)8-7-15-6-5-9-20-12-15/h5-14,21H,1-4H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (Homo sapiens)	BDBM50553592 (CHEMBL4753142) Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@@]1([H])OC(=C[C@H](O)[C@@H]1O)C(=O)NCc1ccc(cc1)N1CCC(CC1)Oc1ccc(OC(F)(F)F)cc1)C(N)=O |r,c:24| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DPAGT1 expressed in HEK293 (Expi293) cells incubated for 2 hrs using UDP-GlcN-Cg-FITC and alpha-dihydroundecap-renyl phosphate by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00545 BindingDB Entry DOI: 10.7270/Q2J38X6H
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50070288 (2-(3,4-Difluoro-benzyl)-3-hydroxy-4-(propane-2-sul...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccc(F)c(F)c2)c(=O)c2ccccc12 Show InChI InChI=1S/C19H17F2NO4S/c1-11(2)27(25,26)17-13-5-3-4-6-14(13)18(23)22(19(17)24)10-12-7-8-15(20)16(21)9-12/h3-9,11,24H,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production; Imax=84%				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50057005 (6-Chloro-3-hydroxy-2-methyl-1-oxo-1,2-dihydro-isoq...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2Cl)c2cc(Cl)ccc2C1=O Show InChI InChI=1S/C17H11Cl3N2O3/c1-22-16(24)10-4-2-8(18)6-11(10)14(17(22)25)15(23)21-13-5-3-9(19)7-12(13)20/h2-7,14H,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50000390 (CHEMBL58990) Show SMILES Cc1cc(\C=C\c2cccs2)cc(Cl)c1O Show InChI InChI=1S/C13H11ClOS/c1-9-7-10(8-12(14)13(9)15)4-5-11-3-2-6-16-11/h2-8,15H,1H3/b5-4+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50056996 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(F)cc2F)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H11ClF2N2O4S/c1-21-16(23)14(10-6-8(17)2-5-13(10)26(21,24)25)15(22)20-12-4-3-9(18)7-11(12)19/h2-7,14H,1H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012790 (4-[2-(2,5-Dimethyl-phenyl)-vinyl]-2,6-dimethyl-phe...) Show SMILES Cc1ccc(C)c(\C=C\c2cc(C)c(O)c(C)c2)c1 Show InChI InChI=1S/C18H20O/c1-12-5-6-13(2)17(9-12)8-7-16-10-14(3)18(19)15(4)11-16/h5-11,19H,1-4H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50070287 (2-(4-Fluoro-benzyl)-3-hydroxy-4-(propane-2-sulfony...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccc(F)cc2)c(=O)c2ccccc12 Show InChI InChI=1S/C19H18FNO4S/c1-12(2)26(24,25)17-15-5-3-4-6-16(15)18(22)21(19(17)23)11-13-7-9-14(20)10-8-13/h3-10,12,23H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50012789 (2,6-Di-tert-butyl-4-(2-pyridin-3-yl-vinyl)-phenol ...) Show SMILES CC(C)(C)c1cc(\C=C\c2cccnc2)cc(c1O)C(C)(C)C Show InChI InChI=1S/C21H27NO/c1-20(2,3)17-12-16(10-9-15-8-7-11-22-14-15)13-18(19(17)23)21(4,5)6/h7-14,23H,1-6H3/b10-9+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012813 (2,6-Dimethyl-4-(2-p-tolyl-vinyl)-phenol | CHEMBL29...) Show SMILES Cc1ccc(\C=C\c2cc(C)c(O)c(C)c2)cc1 Show InChI InChI=1S/C17H18O/c1-12-4-6-15(7-5-12)8-9-16-10-13(2)17(18)14(3)11-16/h4-11,18H,1-3H3/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil 5-lipoxygenase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50070290 (2-Benzyl-3-hydroxy-4-(propane-2-sulfonyl)-2H-isoqu...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccccc2)c(=O)c2ccccc12 Show InChI InChI=1S/C19H19NO4S/c1-13(2)25(23,24)17-15-10-6-7-11-16(15)18(21)20(19(17)22)12-14-8-4-3-5-9-14/h3-11,13,22H,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50012794 (4-[2-(4-Fluoro-phenyl)-ethyl]-2,6-dimethyl-phenol ...) Show SMILES Cc1cc(CCc2ccc(F)cc2)cc(C)c1O Show InChI InChI=1S/C16H17FO/c1-11-9-14(10-12(2)16(11)18)4-3-13-5-7-15(17)8-6-13/h5-10,18H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human platelet Prostaglandin G/H synthase				J Med Chem 33: 1892-8 (1990) BindingDB Entry DOI: 10.7270/Q2W95857
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056996 (6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...) Show SMILES CN1C(=O)C(C(=O)Nc2ccc(F)cc2F)c2cc(Cl)ccc2S1(=O)=O Show InChI InChI=1S/C16H11ClF2N2O4S/c1-21-16(23)14(10-6-8(17)2-5-13(10)26(21,24)25)15(22)20-12-4-3-9(18)7-11(12)19/h2-7,14H,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...				J Med Chem 40: 980-9 (1997) Article DOI: 10.1021/jm9607010 BindingDB Entry DOI: 10.7270/Q2WH2P37
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50070290 (2-Benzyl-3-hydroxy-4-(propane-2-sulfonyl)-2H-isoqu...) Show SMILES CC(C)S(=O)(=O)c1c(O)n(Cc2ccccc2)c(=O)c2ccccc12 Show InChI InChI=1S/C19H19NO4S/c1-13(2)25(23,24)17-15-10-6-7-11-16(15)18(21)20(19(17)22)12-14-8-4-3-5-9-14/h3-11,13,22H,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 production.				Bioorg Med Chem Lett 8: 1181-6 (1999) BindingDB Entry DOI: 10.7270/Q2TQ60PJ
					More data for this Ligand-Target Pair

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