Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interstitial collagenase (Homo sapiens (Human)) | BDBM30344 (Cipemastat | Trocade) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloprotease-1 (MMP1) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50096646 (2-(4'-Chloro-biphenyl-4-yloxymethyl)-N-hydroxy-4-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-13 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50096646 (2-(4'-Chloro-biphenyl-4-yloxymethyl)-N-hydroxy-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-2 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-9 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50096651 (2-(4'-Cyano-biphenyl-4-yloxymethyl)-N-hydroxy-4-(4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-2 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50096649 (2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(4-oxo-4H-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-2 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-2 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50096651 (2-(4'-Cyano-biphenyl-4-yloxymethyl)-N-hydroxy-4-(4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-9 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50096646 (2-(4'-Chloro-biphenyl-4-yloxymethyl)-N-hydroxy-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-9 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50096651 (2-(4'-Cyano-biphenyl-4-yloxymethyl)-N-hydroxy-4-(4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-13 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50452012 (CHEMBL2110187) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of farnesyltransferase | Bioorg Med Chem Lett 14: 767-71 (2004) BindingDB Entry DOI: 10.7270/Q2348JSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50096649 (2-(Biphenyl-4-yloxymethyl)-N-hydroxy-4-(4-oxo-4H-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-9 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-3 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50096651 (2-(4'-Cyano-biphenyl-4-yloxymethyl)-N-hydroxy-4-(4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-3 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50131944 (2-(4-Oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-5-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-3 (MMP3) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50131941 (2-(4'-Chloro-biphenyl-4-ylsulfanylmethyl)-N-hydrox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50092365 ((R)-1-((1H-imidazol-5-yl)methyl)-3-benzyl-4-(thiop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | MMDB PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of farnesyltransferase | Bioorg Med Chem Lett 14: 767-71 (2004) BindingDB Entry DOI: 10.7270/Q2348JSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-1 (MMP1) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-13 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-1 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354621 (3-(6-{4-[(4-Hydroxyphenyl)(methyl)carbamoyl]-1,5-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-9 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-9 (MMP9) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161571 (US9108983, Example 386 | US9108983, Example 449) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50131964 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(3-oxo-6,7,8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-2 | Bioorg Med Chem Lett 11: 295-9 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-2 (MMP2) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354602 (4-[2-(Dimethylamino)ethoxy]phenyl 6-{4-[(4-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50131962 (2-(4'-Chloro-biphenyl-4-sulfonyl)-5-(4-oxo-4H-benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161636 (US9108983, Example 455) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50131953 (2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP13) | J Med Chem 46: 3840-52 (2003) Article DOI: 10.1021/jm0307638 BindingDB Entry DOI: 10.7270/Q2CC11FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354648 ((1r,4r)-4-{[(tert-Butoxy)carbonyl]amino}cyclohexyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM60412 (US9108983, 445) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161553 (US9108983, Example 102) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354597 (2-[2-(Dimethylamino)ethoxy]phenyl 6-{4-[(4-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161578 (US9108983, Example 393) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161536 (US9108983, Example 68) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354619 (3-(6-{4-[(4-Hydroxyphenyl)(methyl)carbamoyl]-1,5-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161610 (US9108983, Example 427) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354624 (3-[2-(Dimethylcarbamoyl)ethyl]phenyl 6-{4-[(4-hydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM352978 (3-{2-[2-(4-Cyanophenyl)acetyl]-7-[(3R)-3-methyl-1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354623 (2-[2-(Dimethylcarbamoyl)ethyl]phenyl 6-{4-[(4-hydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM354593 (Phenyl 6-{4-[(4-hydroxyphenyl)(methyl)carbamoyl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9809574 (2017) BindingDB Entry DOI: 10.7270/Q2MP55DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM161554 (US9108983, Example 108 | US9108983, Example 448) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond... | US Patent US9108983 (2015) BindingDB Entry DOI: 10.7270/Q2PC314Z | |||||||||||
More data for this Ligand-Target Pair |
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