Found 85 hits with Last Name = 'lee' and Initial = 'mc' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50007538
(8-(2-Azetidin-1-yl-ethyl)-3-chloro-6-methyl-7,8-di...)Show InChI InChI=1S/C14H18ClN3OS/c1-17-9-11(3-6-18-4-2-5-18)19-13-12(14(17)20)7-10(15)8-16-13/h7-8,11H,2-6,9H2,1H3/t11-/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the histamine receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50007542
(3-Chloro-8-(2-dimethylamino-ethyl)-6-methyl-7,8-di...)Show InChI InChI=1S/C13H18ClN3OS/c1-16(2)5-4-10-8-17(3)13(19)11-6-9(14)7-15-12(11)18-10/h6-7,10H,4-5,8H2,1-3H3/t10-/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the histamine receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM35938
(1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...)Show InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 | UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the Histamine H1 receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50007536
(CHEMBL24517 | [3-(5-Chloro-pyridin-2-yl)-3-pyridin...)Show InChI InChI=1S/C15H18ClN3/c1-19(2)10-8-13(14-5-3-4-9-17-14)15-7-6-12(16)11-18-15/h3-7,9,11,13H,8,10H2,1-2H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the Histamine H1 receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50007539
(8-(2-Dimethylamino-ethyl)-6-methyl-7,8-dihydro-6H-...)Show InChI InChI=1S/C13H19N3OS/c1-15(2)8-6-10-9-16(3)13(18)11-5-4-7-14-12(11)17-10/h4-5,7,10H,6,8-9H2,1-3H3/t10-/m1/s1 | UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the histamine receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(Bos taurus) | BDBM50225112
(43-715 | Arthrex | Proquazone)Show InChI InChI=1S/C18H18N2O/c1-12(2)20-16-11-13(3)9-10-15(16)17(19-18(20)21)14-7-5-4-6-8-14/h4-12H,1-3H3 | PDB
UniProtKB/SwissProt
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PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description -Log (Ki) value for butyrylcholinesterase by inhibiting DFP |
J Med Chem 27: 1317-21 (1984)
BindingDB Entry DOI: 10.7270/Q25T3NPD |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(Bos taurus) | BDBM50225110
(Amfenac | CHEBI:75915)Show InChI InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18) | PDB
UniProtKB/SwissProt
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MCE PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description -Log (Ki) value for butyrylcholinesterase by inhibiting DFP |
J Med Chem 27: 1317-21 (1984)
BindingDB Entry DOI: 10.7270/Q25T3NPD |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50007540
(CHEMBL279907 | [3-(4-Chloro-phenyl)-3-(5-chloro-py...)Show InChI InChI=1S/C16H18Cl2N2/c1-20(2)10-9-15(12-3-5-13(17)6-4-12)16-8-7-14(18)11-19-16/h3-8,11,15H,9-10H2,1-2H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the Histamine H1 receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50007535
(8-(2-Azetidin-1-yl-ethyl)-3-chloro-6-methyl-7,8-di...)Show InChI InChI=1S/C14H18ClN3OS/c1-17-9-11(3-6-18-4-2-5-18)19-13-12(14(17)20)7-10(15)8-16-13/h7-8,11H,2-6,9H2,1H3/t11-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
A. H. Robins Company, Inc.
Curated by ChEMBL
| Assay Description Inhibition of [3H]-mepyramine binding to the Histamine H1 receptor in guinea pig cortex |
J Med Chem 34: 1314-28 (1991)
BindingDB Entry DOI: 10.7270/Q23F4NMG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(Bos taurus) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
UniProtKB/SwissProt
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Patents
Similars
| PDB PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Antiparasitic activity of the compound against thiamine transporter of Eimeria tenella |
J Med Chem 27: 1317-21 (1984)
BindingDB Entry DOI: 10.7270/Q25T3NPD |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50099957
(CHEMBL3321871)Show InChI InChI=1S/C17H19BrN6/c1-23-6-8-24(9-7-23)13-3-4-14-15(10-13)21-17(20-14)22-16-5-2-12(18)11-19-16/h2-5,10-11H,6-9H2,1H3,(H2,19,20,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
J Med Chem 57: 6642-52 (2014)
Article DOI: 10.1021/jm500715u BindingDB Entry DOI: 10.7270/Q2377BG1 |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50100083
(CHEMBL3321972)Show SMILES CN1CCC(CC1)c1ccc2nc(Nc3ccc(cn3)C(F)(F)F)[nH]c2c1 Show InChI InChI=1S/C19H20F3N5/c1-27-8-6-12(7-9-27)13-2-4-15-16(10-13)25-18(24-15)26-17-5-3-14(11-23-17)19(20,21)22/h2-5,10-12H,6-9H2,1H3,(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
J Med Chem 57: 6642-52 (2014)
Article DOI: 10.1021/jm500715u BindingDB Entry DOI: 10.7270/Q2377BG1 |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50100015
(CHEMBL3321968)Show SMILES CN1CCN(CC1)c1cc(Cl)c2nc(Nc3ccc(Br)cn3)[nH]c2c1 Show InChI InChI=1S/C17H18BrClN6/c1-24-4-6-25(7-5-24)12-8-13(19)16-14(9-12)21-17(23-16)22-15-3-2-11(18)10-20-15/h2-3,8-10H,4-7H2,1H3,(H2,20,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
J Med Chem 57: 6642-52 (2014)
Article DOI: 10.1021/jm500715u BindingDB Entry DOI: 10.7270/Q2377BG1 |
More data for this Ligand-Target Pair | |
Adenosine receptor A3
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant adenosine 3 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50100085
(CHEMBL3321980)Show SMILES CN1CCN(CC1)c1cc2[nH]c(Nc3cc(C4CC4)c(F)c(C)n3)nc2cn1 Show InChI InChI=1S/C20H24FN7/c1-12-19(21)14(13-3-4-13)9-17(23-12)26-20-24-15-10-18(22-11-16(15)25-20)28-7-5-27(2)6-8-28/h9-11,13H,3-8H2,1-2H3,(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
J Med Chem 57: 6642-52 (2014)
Article DOI: 10.1021/jm500715u BindingDB Entry DOI: 10.7270/Q2377BG1 |
More data for this Ligand-Target Pair | |
Vasopressin V1a receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant vasopressin V1a receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant adrenergic beta2 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant opiate delta receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Alpha-2B adrenergic receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant alpha2b receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant adrenergic beta-1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant alpha 1a receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant alpha-2a receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant alpha2c receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant cannabinoid 1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant dopamine D1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant dopamine D2 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant dopamine D3 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant dopamine transporter |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant histamine H1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant histamine H2 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant histamine H3 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant MAOM |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Motilin receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant motilin receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant muscarinic M1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant muscarinic M2 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant muscarinic M3 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Substance-P receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant neurokinin NK1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant neuropeptide Y1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant neuropeptide Y2 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Neurotensin receptor type 1
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant neurotensin NT1 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant niacin receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant norepinephrine transporter |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant opiate kappa receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant opiate mu receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant PDE4D |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant serotonin 5-HT1A receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant serotonin 5-HT2A receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant serotonin 5-HT2B receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant serotonin 5HT2C receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50318666
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21 |r| Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Tropical and Public Health Institute
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant serotonin 5HT3 receptor |
Science 329: 1175-80 (2010)
Article DOI: 10.1126/science.1193225 BindingDB Entry DOI: 10.7270/Q2SB45ZB |
More data for this Ligand-Target Pair | |